Pulmonary fibrosis of sarcoidosis: New approaches, old ideas

American Journal of Respiratory Cell and Molecular Biology

Volumn 29, Issue 3 II, 2003, Pages

  Moller, David R ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFIBROTIC AGENT; BLEOMYCIN; COLCHICINE; CORTICOSTEROID; CYTOKINE; GAMMA INTERFERON; GLUCOCORTICOID; HLA ANTIGEN CLASS 2; HLA DQB1 ANTIGEN; HLA DR ANTIGEN; IMMUNOGLOBULIN G; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; MAJOR HISTOCOMPATIBILITY ANTIGEN; PERFENIDONE; T LYMPHOCYTE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTIGEN PRESENTATION; B LYMPHOCYTE; BACTERIAL INFECTION; CONFERENCE PAPER; CORTICOSTEROID THERAPY; HUMAN; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; LUNG ALVEOLUS MACROPHAGE; LUNG DISEASE; LUNG FIBROSIS; LUNG SARCOIDOSIS; MAJOR HISTOCOMPATIBILITY COMPLEX; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; NONHUMAN; PEPTIDE ANALYSIS; SARCOIDOSIS; T LYMPHOCYTE; THORAX RADIOGRAPHY;

ANTIGENS; CYTOKINES; HUMANS; PULMONARY FIBROSIS; SARCOIDOSIS; TH1 CELLS;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 0041326783     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (43)

1. Kitaichi, M. 1986. Pathology of pulmonary sarcoidosis. Clin. Dermatol. 4:108-115.
2. American Thoracic Society. Statement on sarcoidosis. 1999. Am. J. Respir. Crit. Care Med. 160:736-55.
3. Hillerdal, G., E. Nou, K. Osterman, and B. Schmekel. 1984. Sarcoidosis: epidemiology and prognosis. A 15-year European study. Am. Rev. Respir. Dis. 130:29-32.
4. Rybicki, B. A., M. Major, J. Popovich, Jr, M. J. Maliarik, and M. C. Iannuzzi. 1997. Racial differences in sarcoidosis incidence: a 5-year study in a health maintenance organization.. Am. J. Epidemiol. 145:234-241.
5. Siltzbach, L. E., D. G. James, E. Neville, J. Turiaf, J. P. Battesti, O. P. Sharma, Y. Hosoda, R. Mikami, and M. Odaka. 1974. Course and prognosis of sarcoidosis around the world. Am. J. Med. 57:847-852.
6. Baughman, R. P., A. S. Teirstein, M. A. Judson, M. D. Rossman, H. Yeager, Jr., E. A. Bresnitz, L. DePalo, G. Hunninghake, M. C. Iannuzzi, C. J. Johns, G. McLennan, D. R. Moller, L. S. Newman, D. L. Rabin, C. Rose, B. Rybicki, S. E. Weinberger, M. L. Terrin, G. L. Knatterud, and R. Cherniak. A Case Control Etiologic Study of Sarcoidosis (ACCESS) research group. 2001. Clinical characteristics of patients in a case control study of sarcoidosis. Am. J. Respir. Crit. Care Med. 164:1885-1889.
7. Gideon, N. M., and D. M. Mannino. 1996. Sarcoidosis mortality in the United States 1979-1991: an analysis of multiple-cause mortality data. Am. J. Med. 100:423-427.
8. Wang, J. H., and E. L. Reinherz. 2002. Structural basis of T cell recognition of peptides bound to MHC molecules. Mol. Immunol. 38:1039-1049.
9. Kunkel, S. L., N. W. Lukacs, R. M. Strieter, and S. W. Chensue. 1996. Th1 and Th2 responses regulate experimental lung granuloma development. Sarcoidosis Vasc. Diffuse Lung Dis. 13:120-128.
10. Orme, I. M., and A. M. Cooper. 1999. Cytokine/chemokine cascades in immunity to tuberculosis. Immunol. Today 20:307-312.
11. Moller, D. R. 1999. Cells and cytokines involved in the pathogenesis of sarcoidosis. Sarcoidosis Vasc. Diffuse Lung Dis. 16:24-31.
12. Moller, D. R., J. D. Forman, M. C. Liu, P. W. Noble, B. M. Greenlee, P. Vyas, D. A. Holden, J. M. Forrester, A. Lazarus, M. Wysocka, G. Trinchieri, and C. Karp. 1996. Enhanced expression of IL-12 associated with Th1 cytokine profiles in active pulmonary sarcoidosis. J. Immunol. 156:4952-4960.
13. Greene, C. M., G. Meachery, C. C. Taggart, C. P. Rooney, R. Coakley, S. J. O'Neill, and N. G. McElvaney. 2000. Role of IL-18 in CD4+ T lymphocyte activation in sarcoidosis. J. Immunol. 165:4718-4724.
14. Agostini, C., L. Trentin, M. Facco, R. Sancetta, A. Cerutti, C. Tassinari, L. Cimarosto, F. Adami, A. Cipriani, R. Zambello, et al. 1996. Role of IL-15, IL-2, and their receptors in the development of T cell alveolitis in pulmonary sarcoidosis. J. Immunol. 157:910-918.
15. Rogge, L., A. Papi, D. H. Presky, M. Biffi, L. J. Minetti, D. Miotto, C. Agostini, G. Semenzato, L. M. Fabbri, and F. Sinigaglia. 1999. Antibodies to the IL-12 receptor beta 2 chain mark human Th1 but not Th2 cells in vitro and in vivo. J. Immunol. 162:3926-3932.
16. Baughman, R. P., S. A. Strohofer, J. Buchsbaum, and E. E. Lower. 1990. Release of tumor necrosis factor by alveolar macrophages of patients with sarcoidosis. J. Lab. Clin. Med. 115:36-42.
17. Moller, D. R. 1998. Involvement of T cells and alterations in T cell receptors in sarcoidosis. Semin. Respir. Infect. 13:174-183.
18. Grunewald, J., C. H. Janson, A. Eklund, M. Ohm, O. Olerup, U. Persson, and H. Wigzell. 1992. Restricted V alpha 2.3 gene usage by CD4+ T lymphocytes in bronchoalveolar lavage fluid from sarcoidosis patients correlates with HLA-DR3. Eur. J. Immunol. 22:129-135.
19. Forman, J. D., J. T. Klein, R. F. Silver, M. C. Liu, B. M. Greenlee, and D. R. Moller. 1994. Selective activation and accumulation of oligoclonal V beta-specific T cells in active pulmonary sarcoidosis. J. Clin. Invest. 94:1533-1542.
20. Klein, J. T., T. D. Horn, J. D. Forman, R. F. Silver, A. S. Teirstein, and D. R. Moller. 1995. Selection of oligoclonal V beta-specific T cells in the intradermal response to Kveim-Siltzbach reagent in individuals with sarcoidosis. J. Immunol. 154:1450-1460.
21. Selroos, O., M. Klockars, R. Kekomaki, K. Pentinen, P. Lindstrom, and O. Wager. 1980. Circulating immune complexes in sarcoidosis. J. Clin. Lab. Immunol. 3:129-132.
22. Moller, D. R., and E. S. Chen. 2002. Genetic basis of remitting sarcoidosis: triumph of the trimolecular complex? Am. J. Respir. Cell Mol. Biol. 27:391-395.
23. Rosen, Y. 1994. Sarcoidosis. In D. H. Dail and S. P. Hammer, editors. Pulmonary Pathology, 2nd ed. Springer-Verlag, New York. 13-64.
24. Serpier, H., P. Gillery, V. Salmon-Ehr, R. Garnotel, N. Georges, B. Kalis, and F. X. Maquart. 1997. Antagonistic effects of interferon-gamma and interleukin-4 on fibroblast cultures. J. Invest. Dermatol. 109:158-162.
25. Crystal, R. G., P. B. Bitterman, S. I. Rennard, A. J. Hance, and B. A. Keogh. 1984. Interstitial lung diseases of unknown cause: disorders characterized by chronic inflammation of the lower respiratory tract. N. Engl. J. Med. 310:235-244.
26. Sher, A., and R. L. Coffman. 1992. Regulation of immunity to parasites by T cells and T cell-derived cytokines. Annu. Rev. Immunol. 10:385-409.
27. Chen, E. S., B. M. Greenlee, M. Wills-Karp, and D. R. Moller. 2001. Attenuation of lung inflammation and fibrosis in interferon-γ-deficient mice following intratracheal bleomycin. Am. J. Respir. Cell Mol. Biol. 24:545-555.
28. Gurujeyalakshmi, G., and S. N. Giri. 1995. Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: downregulation of TGF-beta and procollagen I and III gene expression. Exp. Lung Res. 21:791-808.
29. Zuo, F. N. Kaminski, E. Eugui, J. Allard, Z. Yakhini, A. Ben-Dor, L. Lollini, D. Morris, Y. Kim, B. DeLustro, D. Sheppard, A. Pardo, M. Selman, and R. A. Heller. 2002. Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. Proc. Natl. Acad. Sci. USA 399:6292-6297.
30. Chilosi, M., V. Poletti, A. Zamo, M. Lestani, L. Montagna, P. Piccoli, S. Pedron, M. Bertaso, A. Scarpa, B. Murer, A. Cancellieri, R. Maestro, G. Semenzato, and C. Doglioni. 2003. Aberrant Wnt/β-catenin pathway activation in idiopathic pulmonary fibrosis. Am. J. Pathol. 162:1495-1502.
31. Chilosi, M., V. Poletti, B. Murer, M. Lestani, A. Cancellieri, L. Montagna, P. Piccoli, G. Cangi, G. Semenzato, and C. Doglioni. 2002. Abnormal reepithelialization and lung remodeling in idiopathic pulmonary fibrosis: the role of deltaN-p63. Lab. Invest. 82:1335-1345.
32. Liu, J. Y., P. J. Sime, T. Wu, G. S. Warshamana, D. Pociask, S. Y. Tsai, and A. R. Brody. 2001. Transforming growth factor-β(1) overexpression in tumor necrosis factor-α receptor knockout mice induces fibroproliferative lung disease. Am. J. Respir. Cell Mol. Biol. 25:3-7.
33. Teder, P., R. W. Vandivier, D. Jiang, J. Liang, L. Cohn, E. Pure, P. M. Henson, and P. W. Noble. 2002. Resolution of lung inflammation by CD44. Science 296:155-158.
34. Baughman, R. P., E. E. Lower, and R. M. du Bois. 2003. Sarcoidosis. Lancet. 361:1111-1118.
35. Baughman, R. P., M. A. Judson, A. S. Teirstein, D. R. Moller, and E. E. Lower. 2002. Thalidomide for chronic sarcoidosis. Chest 122:227-232.
36. Martinetti, M., M. Luisetti, and M. Cuccia. 2002. HLA and sarcoidosis: new pathogenetic insights. Sarcoidosis Vasc. Diffuse Lung Dis. 19:83-95.
37. Sato, H., J. C. Grutters, P. Pantelidis, A. N. Mizzon, T. Ahmad, A. J. Van Houte, J. W. Lammers, J. M. Van Den Bosch, K. I. Welsh, and R. M. Du Bois. 2002. HLA-DQBI*0201: a marker for good prognosis in British and Dutch patients with sarcoidosis. Am. J. Respir. Cell Mol. Biol. 27:406-412.
38. Zissel, G., J. Homolka, J. Schlaak, M. Schlaak, and J. Muller-Quernheim. 1996. Anti-inflammatory cytokine release by alveolar macrophages in pulmonary sarcoidosis. Am. J. Respir. Crit. Care Med. 154:713-719.
39. Grunewald, J., M. Berlin, O. Olerup, and A. Eklund. 2000. Lung T-helper cells expressing T-cell receptor AV2S3 associate with clinical features of pulmonary sarcoidosis. Am. J. Respir. Crit. Care Med. 161:814-818.
40. Munro, C. S., and D. N. Mitchell. 1987. The Kveim response: still useful, still a puzzle. Thorax 42:321-331.
41. Richter, E., Y. P. Kataria, G. Zissel, J. Homolka, M. Schlaak, and J. Muller-Quernheim. 1999. Analysis of the Kveim-Siltzbach test reagent for bacterial DNA. Am. J. Respir. Crit. Care Med. 159:1981-1984.
42. Lyons, D. J., S. Donald, D. N. Mitchell, and G. L. Asherson. 1992. Chemical inactivation of the Kveim reagent. Respiration 59:22-26.
43. Moller, D. R., B. Greenlee, L. Marzilli, Z. Song, A. Teirstein, F. Askin, and R. Cotter. 2001. Identification of potential etiologic antigens in sarcoidosis using protein immunoblot and MALDI-TOF mass spectroscopy. Am. J. Respir. Crit. Care Med. 163:A215. (Abstr.)