In vitro and ex vivo green fluorescent protein expression in alveolar mammary epithelial cells and mammary glands driven by the distal 5′-regulative sequence and intron 1 of the goat β-casein gene

Reproduction, Fertility and Development

Volumn 15, Issue 3-4, 2003, Pages 231-239

  Wu, Hsi Tien ^a,b   Lin, Chich Sheng ^c   Huang, Mu Chiou ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b NATIONAL APPLIED RESEARCH LABORATORIES   (Taiwan)

^c NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CASEIN; DEXAMETHASONE; GREEN FLUORESCENT PROTEIN; INSULIN; LIPOSOME; MATRIGEL; PROLACTIN;

5' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; BREAST CELL; CELL CULTURE; CELL LINE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTROPORATION; EPITHELIUM CELL; GENE EXPRESSION; GENE FUSION; GENE TRANSFER; GENETIC TRANSFECTION; GOAT; IN VITRO STUDY; INTRON; MAMMARY GLAND; MOLECULAR CLONING; MOUSE; NONHUMAN; PLASMID; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REPORTER GENE; TISSUE SPECIFICITY;

ANIMALIA; CAPRA HIRCUS; MAMMALIA;

EID: 0041326471     PISSN: 10313613     EISSN: None     Source Type: Journal    
DOI: 10.1071/rd01050     Document Type: Article

References (44)

1. Altiok, S., and Groner, B. (1993). Interaction of two sequence-specific single-stranded DNA-binding proteins with an essential region of the β-casein gene promoter is regulated by lactogenic hormones. Mol. Cell. Biol. 13, 7303-10.
2. Bischoff, R., Degryse, E., Perraud, F., Dalemans, W., Ali-Hadji, D., Thepot, D., Devinoy, E., Houdebine, L. M., and Pavirani, A. (1992). A 17.6 kbp region located upstream of the rabbit WAP gene directs high level expression of a functional human protein variant in transgenic mouse milk. FEBS Lett. 305, 265-8.
3. Bleck, G. T., and Bremel, R. D. (1994). Variation in expression of a bovine alpha-lactalbumin transgene in milk of transgenic mice. J. Dairy Sci. 77, 1897-904.
4. Buhler, T. A., Bruyere, T., Went, D. F., Stranzinger, G., and Burki, K. (1995). Rabbit β-casein promoter directs secretion of human interleukin-2 into the milk of transgenic rabbits. Bio/Technology 8, 140-3.
5. Burdon, T., Sankaran, L., Wall, R. J., Spencer, M., and Hennighausen, L. (1991). Expression of a whey acidic protein transgene during mammary development. Evidence for different mechanisms of regulation during pregnancy and lactation. J. Biol. Chem. 266, 6909-14.
6. Cerdan, M. G., Young, J. I., Zino, E., Falzone, T. L., Otero, V., Torres, H. N., and Rubinstein, M. (1998). Accurate spatial and temporal transgene expression driven by a 3.8-kilobase promoter of the bovine β-casein gene in the lactating mouse mammary gland. Mol. Reprod. Dev. 49, 236-45.
7. Doppler, W., Groner, B., and Ball, R. K. (1989). Prolactin and glucocorticoid hormones synergistically induce expression of transfected rat β-casein gene promoter constructs in a mammary epithelial cell line. Proc. Natl Acad. Sci. USA 86, 104-8.
8. Doppler, W., Hock, W., Hofer, P., Groner, B., and Ball, R. K. (1990). Prolactin and glucocorticoid hormones control transcription of the beta-casein gene by kinetically distinct mechanisms. Mol. Endocrinol. 4, 912-19.
9. Doppler, W., Welte, T., and Philipp, S. (1995). CCAAT/enhancer-binding protein isoforms β and α are expressed in mammary epithelial cells and bind to multiple sites in the β-casein gene promoter. J. Biol. Chem. 270, 17 962-9.
10. Ebert, K. M., DiTullio, P., Barry, C. A., Schindler, J. E., Ayres, S. L., Smith, T. E., Pellerin, L. J., Meade, H. M., Denman, J., and Roberts, B. (1994). Induction of human tissue plasminogen activator in the mammary gland of transgenic goats. Biotechnology 12, 699-702.
11. Faerman, A., Barash, I., Puzis, R., Nathan, M., Hurwitz, D. R., and Shani, M. (1995). Dramatic heterogeneity of transgene expression in the mammary gland of lactating mice: a model system to study the synthetic activity of mammary epithelial cells. J. Histochem. Cytochem. 43, 461-70.
12. Glass, R. H., Aggeler, J., Spindle, A., Pedersen, R., and Werb, Z. (1983). Degradation of extracellular matrix by mouse trophoblast outgrowths: a model for implantation. J. Cell Biol. 96, 1108-16.
13. Groner, B., and Gouilleux, F. (1995). Prolactin-mediated gene activation in mammary epithelial cells. Curr. Opin. Genet. Dev. 5, 587-94.
14. Gutierrez, A., Meade, H. M., DiTullio, P., Pollock, D., Harvey, M., Jimenez-Flores, R., Anderson, G. B., Murray, J. D., and Medrano, J. F. (1996). Expression of a bovine kappa-CN cDNA in the mammary gland of transgenic mice utilizing a genomic milk protein gene as an expression cassette. Transgenic Res. 5, 271-9.
15. Houdebine, L. M. (2000). Transgenic animal bioreactors. Transgenic Res. 9, 305-20.
16. Huang, M. C., and Lin, C. S. (1996). Cloning and restriction mapping of goat β-casein gene. J. Agric. Forest. 45, 83-94.
17. Huang, Y. T., Chang, Y. H., Liang, C. T., Chou, C. K., Hong, C. C., and Wu, M. F. (1997). Immunologic and ultrastructural characteristics of T-cell lymphoblastic lymphoma associated with mast cell infiltration in Wistar rat. Lab. Anim. Sci. 47, 209-11.
18. Kang, Y. K., Lee, C. S., Chung, A. S., and Lee, K. K. (1998). Prolactin-inducible enhancer activity of the first intron of the bovine β-casein gene. Mol. Cell 8, 259-65.
19. Kim, S. J., Cho, Y. Y., Lee, K. W., Yu, D. Y., Lee, C. S., Han, Y. M., and Lee, K. K. (1994). Expression of human lactoferrin in milk of transgenic mice by using bovine β-casein/human lactoferrin cDNA fusion gene. Mol. Cell 4, 355-60.
20. Lee, K. F., DeMayo, F. J., Atiee, S. H., and Rosen, J. M. (1988). Tissue-specific expression of the rat β-casein gene in transgenic mice. Nucleic Acids Res. 16, 1027-41.
21. Li, M. L., Aggeler, J., Farson, D. A., Hatier, C., and Hassell, J. (1987). Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells. Proc. Natl Acad. Sci. USA 84, 136-40.
22. Maga, E. A., Anderson, G. B., and Murray, J. D. (1995). The effect of mammary gland expression of human lysozyme on the properties of milk from transgenic mice. J. Dairy Sci. 78, 2645-52.
23. Maschio, A., Brickell, P. M., Kioussis, D., Mellor, A. L., Katz, D., and Craig, R. K. (1991). Transgenic mice carrying the guinea-pig α-lactalbumin gene transcribe milk protein genes in their sebaceous glands during lactation. Biochem. J. 275, 459-67.
24. National Institutes of Health. (1996). 'Guide for the Care and Use of Laboratory Animals.' (National Academy Press: Washington, D. C.)
25. Nemir, M., Bhattacharyya, D., Li, X., Singh, K., Mukherjee, A. B., and Mukherjee, B. B. (2000). Targeted inhibition of osteopontin expression in the mammary gland causes abnormal morphogenesis and lactation deficiency. J. Biol. Chem. 275, 969-76.
26. Petitclerc, D., Attal, J., Théron, M. C., Bearzotti, M., Bolifraud, P., Kann, G., Stinnakre, M. G., Pointu, H., Puissant, C., and Houdebine, L. M. (1995). The effect of various introns and transcription terminators on the efficiency of expression vectors in various cultured cell lines and in the mammary gland of transgenic mice. J. Biotechnol. 40, 169-78.
27. Provot, C., Persuy, M. A., and Mercier, J. C. (1995). Complete sequence of the ovine β-casein-encoding gene and interspecies comparison. Gene 154, 259-63.
28. Rijnkels, M., and Pieper, F. R. (1998). Casein gene-based mammary gland-specific transgene expression. In 'Mammary Gland Transgenesis: Therapeutic Protein Production'. (Eds F. O. Castro and J. Janne.) pp. 41-64. (Springer-Verlag Press: New York.)
29. Rijnkels, M., Kooiman, P. M., Krimpenfort, P. J. A., de Boer, H. A., and Pieper, F. R. (1995). Expression analysis of the individual bovine β -, αs2- and κ-casein genes in transgenic mice. Biochem. J. 311, 929-37.
30. Roberts, B., DiTullio, P., Vitale, J., Hehir, K., and Gordon, K. (1992). Cloning of the goat β-casein-encoding gene and expression in transgenic mice. Gene 121, 255-62.
31. Shani, M., Barash, I., Nathan, M., Ricca, G., Searfoss, G. H., Dekel, I., Faerman, A., Givol, D., and Hurwitz, D. R. (1992). Expression of human serum albumin in the milk of transgenic mice. Transgenic Res. 1, 195-208.
32. Soulier, S., Vilotte, J. L., Stinnakre, M. G., and Mercier, J. C. (1992). Expression analysis of ruminant α-lactalbumin in transgenic mice: developmental regulation and general location of important cis-regulatory elements. FEBS Lett. 297, 13-18.
33. Suzuki, T., Shin, B. C., Fujikura, K., Matsuzaki, T., and Takata, K. (1998). Direct gene transfer into rat liver cells by in vivo electroporation. FEBS Lett. 425, 436-40.
34. Vihinen, T., Maatta, A., Jaakkola, P., Auvinen, P., and Jalkanen, M. (1996). Functional characterization of mouse syndecan-1 promoter. J. Biol. Chem. 271, 12 532-41.
35. Wall, R. J., Kerr, D. E., and Bondioli, K. R. (1997). Transgenic daily cattle: genetic engineering on a large scale. J. Dairy Sci. 80, 2213-24.
36. Wechselberger, C., Ebert, A. D., Bianco, C., Khan, N. I., Sun, Y., Wallace-Jones, B., and Salomon, D. S. (2001). Cripto-1 enhances migration and branching morphogenesis of mouse mammary epithelial cells. Exp. Cell Res. 266, 95-105.
37. Whitelaw C. B., Archibald, A. L., Harris, S., McClenaghan, M., Simons, J. P., and Clark, A. J. (1991). Targeting expression to the mammary gland: intronic sequences can enhance the efficiency of gene expression in transgenic mice. Transgenic Res. 1, 3-13.
38. Winklehner-Jennewein, P., Geymayer, S., Lechner, J., Welte, T., Hansson, L., Geley, S., and Doppler, W. (1998). A distal enhancer region in the human β-casein gene mediates the response to prolactin and glucocorticoid hormones. Gene 217, 127-39.
39. Yoshimura, M., and Oka, T. (1990). Transfection of β-casein chimeric gene and hormonal induction of its expression in primary murine mammary epithelial cells. Proc. Natl Acad. Sci. USA 87, 3670-4.
40. Yuh, I. S., Jang, B. B., and Hong, B. J. (1998). Effects of adenosine and epidermal growth factor on the growth of mouse mammary epithelial cells. Cell Biol. Int. 22, 131-5.
41. Zhang, G., Gurtu, V., and Kain, S. R. (1996). An enhanced green fluorescent protein allows sensitive detection of gene transfer in mammalian cells. Biochem. Biophys. Res. Commun. 227, 707-11.
42. Zhang, K., Lu, D., Xue, J., Huang, Y., and Huang, S. (1998). Construction of mammary gland-specific expression vectors for human clotting factor IX and its secretory expression in goat milk. Chin. J. Biotechnol. 13, 271-6.
43. Ziomek, C. A. (1998). Commercialization of proteins produced in the mammary gland. Theriogenology 49, 139-44.
44. Zolotukhin, S., Potter, M., Hauswirth, W., Guy, J., and Muzyczka, N. (1996). A 'humanized' green fluorescent protein cDNA adapted for high-level expression in mammalian cells. J. Virol. 70, 4646-54.