A negative rapid urease test is unreliable for exclusion of Helicobacter pylori infection during acute phase of ulcer bleeding. A prospective case control study

Digestive and Liver Disease

Volumn 35, Issue 4, 2003, Pages 217-221

  Schilling, D ^a   Demel, A ^a   Adamek, H E ^a   Nusse T ^a   Weidmann, E ^a   Riemann, J F ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Helicobacter pylori infection; Peptic ulcer bleeding; Rapid urease test

Indexed keywords

CARBON 13; PROTON PUMP INHIBITOR; UREA; UREASE; DIAGNOSTIC AGENT;

ADULT; AGED; ARTICLE; BACTERIUM DETECTION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; DUODENUM ULCER; FEMALE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HISTOPATHOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; PEPTIC ULCER BLEEDING; RAPID UREASE TEST; RELIABILITY; SENSITIVITY AND SPECIFICITY; STOMACH ULCER; UREA BREATH TEST; BREATH ANALYSIS; CASE CONTROL STUDY; DIGESTIVE TRACT ENDOSCOPY; ISOLATION AND PURIFICATION; LABORATORY DIAGNOSIS; MICROBIOLOGY; MIDDLE AGED; PATHOLOGY; PREDICTION AND FORECASTING; PREVALENCE; PROSPECTIVE STUDY; REFERENCE VALUE; REPRODUCIBILITY; STOMACH ANTRUM; STOMACH MUCOSA;

ADULT; AGED; AGED, 80 AND OVER; BREATH TESTS; CASE-CONTROL STUDIES; DUODENAL ULCER; ENDOSCOPY, DIGESTIVE SYSTEM; FALSE NEGATIVE REACTIONS; FEMALE; GASTRIC MUCOSA; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MIDDLE AGED; PEPTIC ULCER HEMORRHAGE; PREDICTIVE VALUE OF TESTS; PREVALENCE; PROSPECTIVE STUDIES; PYLORIC ANTRUM; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; UREA; UREASE;

EID: 0041306955     PISSN: 15908658     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1590-8658(03)00058-6     Document Type: Article

References (17)

1. Laine L, Lewin D, Naritoku W, Estrada R, Cohen H. Prospective comparison of commercially available rapid urease tests for the diagnosis of Helicobacter pylori. Gastrointest Endosc 1996;44:523-6.
2. Ell C, Hagenmüller F, Schmitt W, Riemann JF, Hahn EG, Hohenberger P. Multicenter prospective study of the current status of treatment for bleeding ulcer in Germany. Dtsch Med Wochenschr 1995;120:3-9.
3. Rockall TA, Logan RFA, Devlin HB. Incidence of an mortality from acute upper gastrointestinal haemorrhage in the United Kingdom. Br Med J 1995;311:222-6.
4. Riemann JF, Schilling D, Schauwecker P, Wehlen G, Dorlars D, Kohler B, et al. Cure with omeprazole plus amoxicillin versus long term ranitidine therapy in Helicobacter pylori associated peptic ulcer bleeding. Gastrointest Endosc 1997;46:299-304.
5. Lai KC, Hui WM, Wong WM, Wong BCY, Cheng WH, Ching CK, et al. Treatment of Helicobacter pylori in patients with duodenal ulcer hemorrhage: A long term randomized, controlled study. Am J Gastroenterol 2000;95:2225-32.
6. Bravo LE, Realpe JL, Campo C, Correa P. Effects of acid suppression and bismuth medication on performance of diagnostic tests for Helicobacter pylori infection. Am J Gastroenterol 1999;94:2380-3.
7. Lau JYW, Sung YYJ, Lee KKC, Yung M, Wong SKH, Justin CB, et al. Effect of intravenous omeprazole on recurrent bleeding after endoscopic treatment of bleeding peptic ulcers. New Engl J Med 2000;343:310-6.
8. Lee JM, Breslin MB, Fallon MB, O'Morain CA. Rapid urease test lack sensitivity in Helicobacter pylori diagnosis when peptic ulcer disease presents with bleeding. Am J Gastroenterol 2000;95:1166-70.
9. Tu TC, Lee CL, Wu CH, Chen TK, Chan CC, Huang SH, et al. Comparison of invasive and non invasive tests for detecting Helicobacter pylori infection in bleeding peptic ulcers. Gastrointest Endosc 1999;49:302-6.
10. Archimandritis A, Tzivras M, Sougioultzis S, Papaparaskevas I, Apostolopoulos P, Avlami A, et al. Rapid urease test is less sensitive than histology in diagnosing Helicobacter pylori infection in patients with non-variceal upper gastrointestinal bleeding. J Gastroenterol Hepatol 2000;15:369-73.
11. Participants in the International Workshop on the Histopathology of Gastritis Classification and Grading of Gastritis, Dixon MF, Genta RM, Yardley PC. The updated Sydney System. Am J Surg Pathol 1996;20:1161-81.
12. 13C-urea breath test for pre-and posttreatment diagnosis of Helicobacter pylori infection in the routine clinical setting. Am J Gastroenterol 1999;94:2100-4.
13. Kohler B, Benz C, Maier M, Riemann JF. Acute ulcer bleeding. A prospective randomized trial to compare Doppler and Forrest classification in endoscopic diagnosis and therapy. Dig Dis Sci 1997;42:1370-4.
14. Vergara M, Casellas F, Saperas E de Torres I, Lopez J, Borruel N, et al. Helicobacter pylori eradication prevents recurrence from peptic ulcer haemorrhage. Eur J Gastroenterol Hepatol 2000;12:733-7.
15. Lee JM, Breslin NP, Gopaul M, Koh CW, Kong TY, Soong MM, et al. The effects of blood on rapid urease testing for Helicobacter pylori in mucosal biopsies from the gastric antrum. Ir J Med Sci 2000;169:60-2.
16. Perry M, Vakil N, Cuttler AF. Admixture with whole blood does not explain false-negative urease tests. J Clin Gastroenterol 2000;30:64-5.
17. Chan HLY, Wu JCW, Chan FKL, Choi CL, Ching JYL, Lee YT, et al. Is non-Helicobacter pylori, non-NSAID peptic ulcer a common cause of upper GI bleeding? A prospective study of 977 patients. Gastrointest Endosc 2001;53:438-42.