Maturation-dependent thiol loss increases chondrocyte susceptibility to apoptosis

Journal of Bone and Mineral Research

Volumn 18, Issue 4, 2003, Pages 662-668

  Teixeira, Cristina C ^a   Rajpurohit, Ramesh ^b   Mansfield, Kyle ^b   Nemelivsky, Yelena V ^a   Shapiro, Irving M ^c  

^a NEW YORK UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Apoptosis; Chondrocyte maturation; Gene expression; Glutathione; Retinoic acid

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGEN TYPE 10; COLLAGEN TYPE 2; GLUTATHIONE; OSTEOPONTIN; THIOL;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARTILAGE CELL; CELL MATURATION; CELL SURVIVAL; CONTROLLED STUDY; GENE EXPRESSION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PHENOTYPE;

EID: 0041304781     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2003.18.4.662     Document Type: Article

References (27)

1. Hatori M, Klatte KJ, Teixeira CC, Shapiro IM 1995 End labeling studies of fragmented DNA in the avian growth plate: Evidence of apoptosis in terminally differentiated chondrocytes. J Bone Miner Res 10:1960-1968.
2. Gibson GJ, Kohler WJ, Schaffler MB 1995 Chondrocyte apoptosis in endochondral ossification of chick sterna. Dev Dyn 203:468-476.
3. Aizawa T, Kokubun S, Tanaka Y 1997 Apoptosis and proliferation of growth plate chondrocytes in rabbits. J Bone Joint Surg Br 79:483-486.
4. Silvestrini G, Mocetti P, Ballanti P, Di Grezia R, Bonucci E 1998 In vivo incidence of apoptosis evaluated with the TdT FragEL DNA fragmentation detection kit in cartilage and bone cells of the rat tibia. Tissue Cell 30:627-633.
5. Iwamoto M, Shapiro IM, Yagami K, Boskey AL, Leboy PS, Adams SL, Pacifici M 1993 Retinoic acid induces rapid mineralization and expression of mineralization-related genes in chondrocytes. Exp Cell Res 207:413-420.
6. Iwamoto M, Yagami K, Shapiro IM, Leboy PS, Adams SL, Pacifici M 1994 Retinoic acid is a major regulator of chondrocyte maturation and matrix mineralization. Microsc Res Tech 28:483-491.
7. Leboy PS, Vaias L, Uschmann B, Golub E, Adams SL, Pacifici M 1989 Ascorbic acid induces alkaline phosphatase, type X collagen, and calcium deposition in cultured chick chondrocytes. J Biol Chem 264:17281-17286.
8. Shapiro IM, Debolt K, Hatori M, Iwamoto M, Pacifici M 1994 Retinoic acid induces a shift in the energetic state of hypertrophic chondrocytes. J Bone Miner Res 9:1229-1237.
9. Oshima O, Leboy PS, McDonald SA, Tuan RS, Shapiro IM 1989 Developmental expression of genes in chick growth cartilage detected by in situ hybridization. Calcif Tissue Int 45:182-192.
10. Matsumoto H, Debolt K, Shapiro IM 1988 Adenine, guanine, and inosine nucleotides of chick growth cartilage: Relationship between energy status and the mineralization process. J Bone Miner Res 3:347-352.
11. Shapiro IM, Golub EE, Kakuta S, Hazelgrove J, Havery J, Chance B, Frasca P 1982 Initiation of endochondral calcification is related to changes in the redox state of hypertrophic chondrocytes. Science 217:950-952.
12. Teixeira CC, Shapiro IM, Hatori M, Rajpurohit R, Koch C 1996 Retinoic acid modulation of glutathione and cysteine metabolism in chondrocytes. Biochem J 314:21-26.
13. Teixeira CC, Mansfield K, Hertkorn C, Ischiropoulos H, Shapiro IM 2001 Phosphate-induced chondrocyte apoptosis is linked to nitric oxide generation. Am J Physiol 281:C833-C839.
14. Mansfield K, Teixeira CC, Adams CS, Shapiro IM 2001 Phosphate ions mediate chondrocyte apoptosis through a plasma membrane transporter mechanism. Bone 28:1-8.
15. Mansfield K, Rajpurohit R, Shapiro IM 1999 Extracellular phosphate ions cause apoptosis of terminally differentiated epiphyseal chondrocytes. J Cell Physiol 179:276-286.
16. Mosmann T 1983 Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63.
17. van de Loosdrecht AA, Beelen RH, Ossenkoppele GJ, Broekhoven MG, Langenhuüsen MM 1994 A tetrazolium-based colorimetric MTT assay to quantitate human monocyte mediated cytotoxicity against leukemic cells from cell lines and patients with acute myeloid leukemia. J Immunol Methods 174:311-320.
18. McGahon AJ, Martin SJ, Bissonnette RP, Mahboubi A, Shi Y, Mogil RJ, Nishioka WK, Green DR 1995 The end of the (cell) line: Methods for the study of apoptosis in vitro. Methods Cell Biol 46:153-185.
19. Koch CJ, Skov KA 1994 Enhanced radiation-sensitivity by preincubation with nitroimidazoles: Effect of glutathione depletion. Int J Radiat Oncol Biol Phys 29:345-349.
20. Young MF, Vogeli G, Nunez AM, Fernandez MP, Sullivan M, Sobel ME 1984 Isolation of cDNA and genomic DNA clones encoding type II collagen. Nucleic Acids Res 12:4207-4228.
21. Leboy PS, Shapiro IM, Uschmann BD, Oshima O, Lin D 1988 Gene expression in mineralizing chick epiphyseal cartilage. J Biol Chem 263:8515-8520.
22. Moore MA, Gotoh Y, Rafidi K, Gerstenfeld LC 1991 Characterization of a cDNA for chicken osteopontin: Expression during bone development, osteoblast differentiation, and tissue distribution. Biochemistry 30:2501-2508.
23. Teixeira CC, Hatori M, Leboy PS, Pacifici M, Shapiro IM 1995 A rapid and ultrasensitive method for measurement of DNA, calcium and protein content, and alkaline phosphatase activity of chondrocyte cultures. Calcif Tissue Int 56:252-256.
24. Habuchi O, Miyachi T, Kaigawa S, Nakashima S, Fujiwara C, Hisada M 1991 Effects of glutathione depletion on the synthesis of proteoglycan and collagen in cultured chondrocytes. Biochim Biophys Acta 1093:153-161.
25. Gomez DA, Martinez-Martinez S, Calvo V, Armesilla AL, Redondo JM 1997 Antioxidants and AP-1 activation: A brief overview. Immunobiology 198:273-278.
26. Kameda T, Watanabe H, Iba H 1997 C-Jun and JunD suppress maturation of chondrocytes. Cell Growth Differ 8:495-503.
27. Matsumoto H, Silverton SF, Debolt K, Shapiro IM 1991 Superoxide dismutase and catalase activities in the growth cartilage: Relationship between oxidoreductase acfivity and chondrocyte maturation. J Bone Miner Res 6:569-574.