메뉴 건너뛰기




Volumn 30, Issue 6, 1998, Pages 627-633

In vivo incidence of apoptosis evaluated with the TdT FragEL™ DNA fragmentation detection kit in cartilage and bone cells of the rat tibia

Author keywords

Apoptosis; Chondrocytes; Osteoblasts; Osteoclasts; Osteocytes; TUNEL method

Indexed keywords

DNA FRAGMENT; DNA NUCLEOTIDYLEXOTRANSFERASE;

EID: 0032427289     PISSN: 00408166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-8166(98)80081-5     Document Type: Article
Times cited : (26)

References (65)
  • 1
    • 0027516486 scopus 로고
    • Expression of tissue transglutaminase in skeletal tissues correlates with events of terminal differentiation of chondrocytes
    • Aeschlimann, D., Wetterwald, A., Fleisch, H. and Paulsson, M. 1993. Expression of tissue transglutaminase in skeletal tissues correlates with events of terminal differentiation of chondrocytes. J. Cell Biol., 120, 1461-1470.
    • (1993) J. Cell Biol. , vol.120 , pp. 1461-1470
    • Aeschlimann, D.1    Wetterwald, A.2    Fleisch, H.3    Paulsson, M.4
  • 2
    • 0030990754 scopus 로고    scopus 로고
    • Apoptosis and proliferation of growth plate chondrocytes in rabbits
    • Aizawa, T., Kokubun, S. and Tanaka, Y. 1997. Apoptosis and proliferation of growth plate chondrocytes in rabbits. J. Bone Joint Surg., 79B, 483-486.
    • (1997) J. Bone Joint Surg. , vol.79 B , pp. 483-486
    • Aizawa, T.1    Kokubun, S.2    Tanaka, Y.3
  • 3
    • 0031013458 scopus 로고    scopus 로고
    • Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocytes maturation during skeletal development
    • Amling, M., Neff, L., Tanaka, S. et al. 1997. Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocytes maturation during skeletal development. J. Cell Biol., 136, 205-213.
    • (1997) J. Cell Biol. , vol.136 , pp. 205-213
    • Amling, M.1    Neff, L.2    Tanaka, S.3
  • 4
    • 0642330840 scopus 로고
    • A topographic quantitative study of bone formation and reconstruction
    • Blackwood, E.J.J. (ed) The MacMillan Co., New York
    • Amprino, R. and Marotti, G. 1964. A topographic quantitative study of bone formation and reconstruction. In: Blackwood, E.J.J. (ed) Bone and tooth symposium. The MacMillan Co., New York, 21-33.
    • (1964) Bone and Tooth Symposium , pp. 21-33
    • Amprino, R.1    Marotti, G.2
  • 5
    • 0025247903 scopus 로고
    • Apoptosis. The role of the endonuclease
    • Arends, M.J., Morris, R.G. and Wyllie, A.H. 1990. Apoptosis. The role of the endonuclease. Am. J. Pathol., 136, 593-608.
    • (1990) Am. J. Pathol. , vol.136 , pp. 593-608
    • Arends, M.J.1    Morris, R.G.2    Wyllie, A.H.3
  • 6
    • 0014703191 scopus 로고
    • Fine structure and histochemistry of 'calcifying globules' in epiphyseal cartilage
    • Bonucci, E. 1970. Fine structure and histochemistry of 'calcifying globules' in epiphyseal cartilage. Z. Zellforsch., 103, 192-217.
    • (1970) Z. Zellforsch. , vol.103 , pp. 192-217
    • Bonucci, E.1
  • 7
    • 0026523307 scopus 로고
    • Extracellular alkaline phosphatase activity in mineralizing matrices of cartilage and bone: Ultrastructural localization using a cerium-based method
    • Bonucci, E., Silvestrini, G. and Bianco, P. 1992. Extracellular alkaline phosphatase activity in mineralizing matrices of cartilage and bone: ultrastructural localization using a cerium-based method. Histochemistry, 97, 323-327.
    • (1992) Histochemistry , vol.97 , pp. 323-327
    • Bonucci, E.1    Silvestrini, G.2    Bianco, P.3
  • 8
    • 0029829117 scopus 로고    scopus 로고
    • DNA fragmentation during bone formation in neonatal rodents assessed by transferase-mediated end-labeling
    • Bronckers, A.L.J.J., Goei, W., Luo, G. et al. 1996. DNA fragmentation during bone formation in neonatal rodents assessed by transferase-mediated end-labeling. J. Bone Miner. Res., 11, 1281-1291.
    • (1996) J. Bone Miner. Res. , vol.11 , pp. 1281-1291
    • Bronckers, A.L.J.J.1    Goei, W.2    Luo, G.3
  • 9
    • 0030805263 scopus 로고    scopus 로고
    • Glucocorticoids inhibit bone resorption by isolated rat osteoclasts by enhancing apoptosis
    • Dempster, D.W., Moonga, B.S., Stein, L.S., Herbert, W.R. and Antakly, T. 1997. Glucocorticoids inhibit bone resorption by isolated rat osteoclasts by enhancing apoptosis. J. Endocrinol., 154, 397-406.
    • (1997) J. Endocrinol. , vol.154 , pp. 397-406
    • Dempster, D.W.1    Moonga, B.S.2    Stein, L.S.3    Herbert, W.R.4    Antakly, T.5
  • 10
    • 0026555661 scopus 로고
    • Hypertrophic chondrocytes undergo further differentiation in culture
    • Descalzi Cancedda, F., Gentili, C., Manduca, P. and Cancedda, R. 1992. Hypertrophic chondrocytes undergo further differentiation in culture. J. Cell Biol., 117, 427-435.
    • (1992) J. Cell Biol. , vol.117 , pp. 427-435
    • Descalzi Cancedda, F.1    Gentili, C.2    Manduca, P.3    Cancedda, R.4
  • 11
    • 0025485305 scopus 로고
    • Visualization of living terminal hypertrophic chondrocytes of growth plate cartilage in situ by differential interference contrast microscopy and time-lapse cinematography
    • Farnum, C.E., Turgai, J. and Wilsman, N.J. 1990. Visualization of living terminal hypertrophic chondrocytes of growth plate cartilage in situ by differential interference contrast microscopy and time-lapse cinematography. J. Orthop. Res., 8, 750-763.
    • (1990) J. Orthop. Res. , vol.8 , pp. 750-763
    • Farnum, C.E.1    Turgai, J.2    Wilsman, N.J.3
  • 12
    • 0024361393 scopus 로고
    • Cellular turnover at the chondro-osseus junction of growth plate cartilage: Analysis by serial sections at the light microscopical level
    • Farnum, C.E. and Wilsman, N.J. 1989. Cellular turnover at the chondro-osseus junction of growth plate cartilage: analysis by serial sections at the light microscopical level. J. Orthop. Res., 7, 654-661.
    • (1989) J. Orthop. Res. , vol.7 , pp. 654-661
    • Farnum, C.E.1    Wilsman, N.J.2
  • 13
    • 0028111656 scopus 로고
    • Hypertrophic chondrocytes undergo further differentiation to osteoblast-like cells and participate in the initial bone formation in developing chick embryo
    • Galotto, M., Campanile, G., Robino, G., Descalzi Cancedda, F., Bianco, P. and Cancedda, R. 1994. Hypertrophic chondrocytes undergo further differentiation to osteoblast-like cells and participate in the initial bone formation in developing chick embryo. J. Bone Miner. Res., 9, 1239-1249.
    • (1994) J. Bone Miner. Res. , vol.9 , pp. 1239-1249
    • Galotto, M.1    Campanile, G.2    Robino, G.3    Descalzi Cancedda, F.4    Bianco, P.5    Cancedda, R.6
  • 14
    • 0027137599 scopus 로고
    • Chronic elevation of plasma corticosterone causes reductions in the number of cycling cells of the B lineage in murine bone marrow and induces apoptosis
    • Garvy, B.A., King, L.E., Telford, W.G., Morford, L.A. and Fraker, P.J. 1993. Chronic elevation of plasma corticosterone causes reductions in the number of cycling cells of the B lineage in murine bone marrow and induces apoptosis. Immunology, 80, 587-592.
    • (1993) Immunology , vol.80 , pp. 587-592
    • Garvy, B.A.1    King, L.E.2    Telford, W.G.3    Morford, L.A.4    Fraker, P.J.5
  • 15
    • 0027277091 scopus 로고
    • Glucocorticoids and irradiation-induced apoptosis in normal murine bone marrow B-lineage lynphocytes as determined by flow cytometry
    • Garvy, B.A., Telford, W.G., King, L.E. and Fraker, P.J. 1993. Glucocorticoids and irradiation-induced apoptosis in normal murine bone marrow B-lineage lynphocytes as determined by flow cytometry. Immunology, 79, 270-277.
    • (1993) Immunology , vol.79 , pp. 270-277
    • Garvy, B.A.1    Telford, W.G.2    King, L.E.3    Fraker, P.J.4
  • 16
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli, Y., Sherman, Y. and Ben-Sasson, S.A. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol., 119, 493-501.
    • (1992) J. Cell Biol. , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 17
    • 0029091889 scopus 로고
    • Chondrocyte apoptosis in endochondral ossification of chick sterna
    • Gibson, G.T., Kohler, W.J. and Schaffler, M.B. 1995. Chondrocyte apoptosis in endochondral ossification of chick sterna. Developm. Dynamics, 203, 468-476.
    • (1995) Developm. Dynamics , vol.203 , pp. 468-476
    • Gibson, G.T.1    Kohler, W.J.2    Schaffler, M.B.3
  • 18
    • 0031570781 scopus 로고    scopus 로고
    • Apoptosis of terminally differentiated chondrocytes in culture
    • Gibson, G., Lin, D.L. and Roque, M. 1997. Apoptosis of terminally differentiated chondrocytes in culture. Exp. Cell Res., 233, 372-382.
    • (1997) Exp. Cell Res. , vol.233 , pp. 372-382
    • Gibson, G.1    Lin, D.L.2    Roque, M.3
  • 19
    • 0028136653 scopus 로고
    • Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques
    • Gold, R., Schmied, M., Giegerich, G. et al. 1994. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques. Lab. Invest. 71, 219-225.
    • (1994) Lab. Invest. , vol.71 , pp. 219-225
    • Gold, R.1    Schmied, M.2    Giegerich, G.3
  • 20
    • 0027269557 scopus 로고
    • Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays
    • Gorczyca, W., Gong, J. and Darzynkiewicz, Z. 1993 Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res., 53, 1945-1951.
    • (1993) Cancer Res. , vol.53 , pp. 1945-1951
    • Gorczyca, W.1    Gong, J.2    Darzynkiewicz, Z.3
  • 21
    • 0029959882 scopus 로고    scopus 로고
    • Apoptosis: Molecular regulation of cell death
    • Hale, A.J., Smith, C.A., Sutherland, L.C. et al. 1996. Apoptosis: molecular regulation of cell death. Eur. J. Biochem., 236, 1-26.
    • (1996) Eur. J. Biochem. , vol.236 , pp. 1-26
    • Hale, A.J.1    Smith, C.A.2    Sutherland, L.C.3
  • 22
    • 0028834451 scopus 로고
    • End labeling studies of fragmented DNA in the avian growth plate: Evidence of apoptosis in terminally differentiated chondrocytes
    • Hatori, M., Klatte, K.J., Teixeira, C.C. and Shapiro, I.M. 1995. End labeling studies of fragmented DNA in the avian growth plate: evidence of apoptosis in terminally differentiated chondrocytes. J. Bone Miner. Res., 10, 1960-1968.
    • (1995) J. Bone Miner. Res. , vol.10 , pp. 1960-1968
    • Hatori, M.1    Klatte, K.J.2    Teixeira, C.C.3    Shapiro, I.M.4
  • 23
    • 0029798819 scopus 로고    scopus 로고
    • Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-β
    • Hughes, D.E., Dai, A., Tiffee, J.C., Li, H.H., Mundy, G.R. and Boyce, B.F. 1996. Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-β. Nat. Med., 2, 1132-1136.
    • (1996) Nat. Med. , vol.2 , pp. 1132-1136
    • Hughes, D.E.1    Dai, A.2    Tiffee, J.C.3    Li, H.H.4    Mundy, G.R.5    Boyce, B.F.6
  • 25
    • 0029133135 scopus 로고
    • Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo
    • Hughes, D.E., Wright, K.R., Uy, H.L. et al. 1995. Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo. J. Bone Miner. Res., 10, 1478-1487.
    • (1995) J. Bone Miner. Res. , vol.10 , pp. 1478-1487
    • Hughes, D.E.1    Wright, K.R.2    Uy, H.L.3
  • 26
    • 0028067659 scopus 로고
    • Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes
    • Hunziker, E.B. 1994. Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes. Microsc. Res. Techniq., 28, 505-519.
    • (1994) Microsc. Res. Techniq. , vol.28 , pp. 505-519
    • Hunziker, E.B.1
  • 27
    • 0021366607 scopus 로고
    • Cartilage ultrastructure after high pressure freezing, freeze substitution, and low temperature embedding. I. Chondrocyte ultrastructure - Implications for the theories of mineralization and vascular invasion
    • Hunziker, E.B., Herrmann, W., Schenk, R.K., Mueller, M. and Moor, H. 1984. Cartilage ultrastructure after high pressure freezing, freeze substitution, and low temperature embedding. I. Chondrocyte ultrastructure - implications for the theories of mineralization and vascular invasion. J. Cell Biol., 98, 267-276.
    • (1984) J. Cell Biol. , vol.98 , pp. 267-276
    • Hunziker, E.B.1    Herrmann, W.2    Schenk, R.K.3    Mueller, M.4    Moor, H.5
  • 28
    • 13144268990 scopus 로고    scopus 로고
    • Demonstration of programmed cell death (apoptosis) in osteoblasts: Evidence for modulation of this process by growth factors and cytokines
    • Jilka, R.L., Weinstein, R.S., Bellido, T. et al. 1996. Demonstration of programmed cell death (apoptosis) in osteoblasts: evidence for modulation of this process by growth factors and cytokines. J. Bone Miner. Res., 11(suppl 1), P213.
    • (1996) J. Bone Miner. Res. , vol.11 , Issue.1 SUPPL.
    • Jilka, R.L.1    Weinstein, R.S.2    Bellido, T.3
  • 29
    • 0030750208 scopus 로고    scopus 로고
    • Estrogen inhibits bone resorption by directly inducing apoptosis of the bone-resorbing osteoclasts
    • Kameda, T., Mano, H., Yuasa, T. et al. 1997. Estrogen inhibits bone resorption by directly inducing apoptosis of the bone-resorbing osteoclasts. J. Exp. Med., 186, 489-495.
    • (1997) J. Exp. Med. , vol.186 , pp. 489-495
    • Kameda, T.1    Mano, H.2    Yuasa, T.3
  • 30
    • 0029664497 scopus 로고    scopus 로고
    • 2 inhibits osteoclastic bone resorption by inducing osteoclast apoptosis
    • 2 inhibits osteoclastic bone resorption by inducing osteoclast apoptosis. Biochem. Biophys. Res. Comm., 220, 515-519.
    • (1996) Biochem. Biophys. Res. Comm. , vol.220 , pp. 515-519
    • Kameda, T.1    Miyazawa, K.2    Mori, T.3
  • 31
    • 0029549408 scopus 로고
    • Apoptosis and calcification
    • Kim, K.M. 1995. Apoptosis and calcification. Scann. Microsc., 9, 1137-1178.
    • (1995) Scann. Microsc. , vol.9 , pp. 1137-1178
    • Kim, K.M.1
  • 32
    • 0029998236 scopus 로고    scopus 로고
    • Biotin- or digoxigenine-conjugated nucleotides bind to matrix vesicles in atherosclerotic plaques
    • Kockx, M., Muhring, J., Bortier, H., De Meyer, G.R.Y. and Jacob, W. 1996. Biotin- or digoxigenine-conjugated nucleotides bind to matrix vesicles in atherosclerotic plaques. Am. J. Pathol., 148, 1771-1777.
    • (1996) Am. J. Pathol. , vol.148 , pp. 1771-1777
    • Kockx, M.1    Muhring, J.2    Bortier, H.3    De Meyer, G.R.Y.4    Jacob, W.5
  • 33
    • 0030867723 scopus 로고    scopus 로고
    • Apoptosis is coordinately regulated with osteoblast formation during bone healing
    • Landry, P., Sadasivan, K., Marino, A. and Albright, J. 1997. Apoptosis is coordinately regulated with osteoblast formation during bone healing. Tissue & Cell, 29, 413-419.
    • (1997) Tissue & Cell , vol.29 , pp. 413-419
    • Landry, P.1    Sadasivan, K.2    Marino, A.3    Albright, J.4
  • 35
    • 0029865369 scopus 로고    scopus 로고
    • Osteoclast demise in the rat: Physiological versus degenerative cell death
    • Lutton, J.D., Moonga, B.S. and Dempster, D.W. 1996. Osteoclast demise in the rat: physiological versus degenerative cell death. Exper. Physiol., 81, 251-260.
    • (1996) Exper. Physiol. , vol.81 , pp. 251-260
    • Lutton, J.D.1    Moonga, B.S.2    Dempster, D.W.3
  • 36
    • 0028891783 scopus 로고
    • Apoptosis, oncosis, and necrosis
    • Majino, G. and Joris, I. 1995. Apoptosis, oncosis, and necrosis. Am. J. Pathol., 146, 3-15.
    • (1995) Am. J. Pathol. , vol.146 , pp. 3-15
    • Majino, G.1    Joris, I.2
  • 37
    • 0006192737 scopus 로고
    • Decrement in volume of osteoblasts during osteon formation and its effect on the size of the corresponding osteocytes
    • Meunier, P.J. (ed) Armour Montagu, Paris
    • Marotti, G. 1977. Decrement in volume of osteoblasts during osteon formation and its effect on the size of the corresponding osteocytes. In: Meunier, P.J. (ed) Bone histomorphometry. Armour Montagu, Paris, 385-397.
    • (1977) Bone Histomorphometry , pp. 385-397
    • Marotti, G.1
  • 38
    • 0029938521 scopus 로고    scopus 로고
    • The role of calcium in the regulation of apoptosis
    • McConkey, D.J. and Orrenius, S. 1996. The role of calcium in the regulation of apoptosis. J. Leukoc. Biol., 59, 775-783.
    • (1996) J. Leukoc. Biol. , vol.59 , pp. 775-783
    • McConkey, D.J.1    Orrenius, S.2
  • 39
    • 84909676346 scopus 로고
    • Parameters and indices of bone resorption
    • Meunier, P.J. (ed), Armour Montagu, Toulouse
    • Meunier, P.J. 1976. Parameters and indices of bone resorption. In: Meunier, P.J. (ed), Bone histomorphometry. Armour Montagu, Toulouse, 193-235.
    • (1976) Bone Histomorphometry , pp. 193-235
    • Meunier, P.J.1
  • 40
    • 0009687871 scopus 로고    scopus 로고
    • Regulatory mechanisms of osteoclast differentiation and function
    • Mundy, G.R. 1996. Regulatory mechanisms of osteoclast differentiation and function. J. Bone Miner. Metab., 14, 59-64.
    • (1996) J. Bone Miner. Metab. , vol.14 , pp. 59-64
    • Mundy, G.R.1
  • 41
    • 0030951831 scopus 로고    scopus 로고
    • Identification of apoptotic changes in osteocytes in normal and pathological human bone
    • Noble, B.S., Stevens, H., Loveridge, N. and Reeve, J. 1997. Identification of apoptotic changes in osteocytes in normal and pathological human bone. Bone, 20, 273-282.
    • (1997) Bone , vol.20 , pp. 273-282
    • Noble, B.S.1    Stevens, H.2    Loveridge, N.3    Reeve, J.4
  • 42
    • 13144249607 scopus 로고    scopus 로고
    • Human osteosarcoma (HOS TE-85) cells undergo an apoptotic process that is inhibited by IGF-1
    • Nuttal, M.E. and Gowen, M. 1996. Human osteosarcoma (HOS TE-85) cells undergo an apoptotic process that is inhibited by IGF-1. J. Bone Miner. Res., 11(suppl 1), T301.
    • (1996) J. Bone Miner. Res. , vol.11 , Issue.1 SUPPL.
    • Nuttal, M.E.1    Gowen, M.2
  • 43
    • 0027412343 scopus 로고
    • Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of an endonuclease
    • Oberhammer, F., Fritsch, G., Schmied, M. et al. 1993. Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of an endonuclease. J. Cell Sci., 104, 317-326.
    • (1993) J. Cell Sci. , vol.104 , pp. 317-326
    • Oberhammer, F.1    Fritsch, G.2    Schmied, M.3
  • 44
    • 0030756460 scopus 로고    scopus 로고
    • Further observations on programmed cell death in the epiphyseal growth plate: Comparison of normal and dyschondroplastic epiphyses
    • Ohyama, K., Farquharson, C., Whitehead, C.C. and Shapiro, I.M. 1997. Further observations on programmed cell death in the epiphyseal growth plate: comparison of normal and dyschondroplastic epiphyses. J. Bone Miner. Res., 12, 1647-1656.
    • (1997) J. Bone Miner. Res. , vol.12 , pp. 1647-1656
    • Ohyama, K.1    Farquharson, C.2    Whitehead, C.C.3    Shapiro, I.M.4
  • 46
    • 0028670390 scopus 로고
    • Apoptosis and macrophage-mediated cell deletion in the regulation of B lyphopoiesis in mouse bone marrow
    • Osmond, D.G., Rico-Vargas, S., Valenzona, H. et al. 1994. Apoptosis and macrophage-mediated cell deletion in the regulation of B lyphopoiesis in mouse bone marrow. Immunol. Rev., 142, 209-230.
    • (1994) Immunol. Rev. , vol.142 , pp. 209-230
    • Osmond, D.G.1    Rico-Vargas, S.2    Valenzona, H.3
  • 47
    • 0025102770 scopus 로고
    • Hypertrophic chondrocytes. The terminal stage of differentiation in the chondrogenic cell lineage?
    • Pacifici, M., Golden, E.B., Oshima, O., Shapiro, I.M., Leboy, P.S. and Adams, S.L. 1990. Hypertrophic chondrocytes. The terminal stage of differentiation in the chondrogenic cell lineage? Ann. N. Y. Acad. Sci., 599, 45-57.
    • (1990) Ann. N. Y. Acad. Sci. , vol.599 , pp. 45-57
    • Pacifici, M.1    Golden, E.B.2    Oshima, O.3    Shapiro, I.M.4    Leboy, P.S.5    Adams, S.L.6
  • 48
    • 0030039250 scopus 로고    scopus 로고
    • A new model for the regulation of bone resorption, with particular reference to the effects of bisphosphonates
    • Parfitt, A.M., Mundy, G.R., Roodman, G.D., Hughes, D.E. and Boyce, B.F. 1996. A new model for the regulation of bone resorption, with particular reference to the effects of bisphosphonates. J. Bone Miner. Res., 11, 150-159.
    • (1996) J. Bone Miner. Res. , vol.11 , pp. 150-159
    • Parfitt, A.M.1    Mundy, G.R.2    Roodman, G.D.3    Hughes, D.E.4    Boyce, B.F.5
  • 49
    • 0001786414 scopus 로고
    • The growth plate: Cellular physiology, cartilage assembly and mineralization
    • Hall, B. and Newman, S. (eds) CRC Press, Boca Raton, FL
    • Poole, A.R. 1991. The growth plate: cellular physiology, cartilage assembly and mineralization. In: Hall, B. and Newman, S. (eds) Cartilage: molecular aspects. CRC Press, Boca Raton, FL, 179-211.
    • (1991) Cartilage: Molecular Aspects , pp. 179-211
    • Poole, A.R.1
  • 50
    • 0026758964 scopus 로고
    • Trans-differentiation of hypertrophic chondrocytes into cells capable of producing a mineralized bone matrix
    • Roach, H.I. 1992. Trans-differentiation of hypertrophic chondrocytes into cells capable of producing a mineralized bone matrix. Bone and Mineral, 19, 1-20.
    • (1992) Bone and Mineral , vol.19 , pp. 1-20
    • Roach, H.I.1
  • 51
    • 0030968234 scopus 로고    scopus 로고
    • New aspects of endochondral ossification in the chick: Chondrocyte apoptosis, bone formation by former chondrocytes, and acid phosphatase activity in the endochondral bone matrix
    • Roach, H.I. 1997. New aspects of endochondral ossification in the chick: chondrocyte apoptosis, bone formation by former chondrocytes, and acid phosphatase activity in the endochondral bone matrix. J. Bone Miner. Res., 12, 795-805.
    • (1997) J. Bone Miner. Res. , vol.12 , pp. 795-805
    • Roach, H.I.1
  • 52
    • 0030425207 scopus 로고    scopus 로고
    • The phenotypic switch from chondrocytes to bone-forming cells involves asymmetric cell division and apoptosis
    • Roach, H.I. and Erenpreisa, J. 1996. The phenotypic switch from chondrocytes to bone-forming cells involves asymmetric cell division and apoptosis. Connect. Tissue Res., 35, 85-91.
    • (1996) Connect. Tissue Res. , vol.35 , pp. 85-91
    • Roach, H.I.1    Erenpreisa, J.2
  • 53
    • 0028826658 scopus 로고
    • Osteogenic differentiation of hypertrophic chondrocytes involves asymmetric cell divisions and apoptosis
    • Roach, H.I., Erenpreisa, J. and Aigner, T. 1995. Osteogenic differentiation of hypertrophic chondrocytes involves asymmetric cell divisions and apoptosis. J. Cell Biol., 131, 483-494.
    • (1995) J. Cell Biol. , vol.131 , pp. 483-494
    • Roach, H.I.1    Erenpreisa, J.2    Aigner, T.3
  • 54
    • 0029766224 scopus 로고    scopus 로고
    • Biphosphonates induce apoptosis in mouse macrophage-like cells in vitro by a nitric oxide-independent mechanism
    • Rogers, M.J., Chilton, K.M., Coxon, F.P. et al. 1996. Biphosphonates induce apoptosis in mouse macrophage-like cells in vitro by a nitric oxide-independent mechanism. J. Bone Miner. Res., 11, 1482-1491.
    • (1996) J. Bone Miner. Res. , vol.11 , pp. 1482-1491
    • Rogers, M.J.1    Chilton, K.M.2    Coxon, F.P.3
  • 55
    • 0027994239 scopus 로고
    • Cell nucleus and DNA fragmentation are not required for apoptosis
    • Schulze-Osthoff, K., Walczak, H., Droge, W. and Krammer, P.H. 1994. Cell nucleus and DNA fragmentation are not required for apoptosis J. Cell Biol., 127, 15-20.
    • (1994) J. Cell Biol. , vol.127 , pp. 15-20
    • Schulze-Osthoff, K.1    Walczak, H.2    Droge, W.3    Krammer, P.H.4
  • 57
    • 0026028564 scopus 로고
    • Transdifferentiation of hypertrophic chondrocytes into osteoblasts in murine fetal metatarsal bones, induced by co-cultured cerebrum
    • Thesingh, C.W., Groot, C.G. and Wassenaar, A.M. 1991. Transdifferentiation of hypertrophic chondrocytes into osteoblasts in murine fetal metatarsal bones, induced by co-cultured cerebrum. Bone and Mineral, 12, 25-40.
    • (1991) Bone and Mineral , vol.12 , pp. 25-40
    • Thesingh, C.W.1    Groot, C.G.2    Wassenaar, A.M.3
  • 58
    • 0030884639 scopus 로고    scopus 로고
    • The death of osteocytes via apoptosis accompanies estrogen withdrawal in human bone
    • Tomkinson, A., Reeve, J., Shaw, R.W. and Noble, B.S. 1997. The death of osteocytes via apoptosis accompanies estrogen withdrawal in human bone. J. Clin. Endocrinol. Metab., 82, 3128-3135.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 3128-3135
    • Tomkinson, A.1    Reeve, J.2    Shaw, R.W.3    Noble, B.S.4
  • 60
    • 0030879337 scopus 로고    scopus 로고
    • Expression of Bcl-2 protein in the epiphyseal plate cartilage and trabecular bone of growing rats
    • Wang, Y., Toury, R., Hauchecorne, M. and Balmain, N. 1997. Expression of Bcl-2 protein in the epiphyseal plate cartilage and trabecular bone of growing rats. Histochem. Cell. Biol., 108, 45-55.
    • (1997) Histochem. Cell. Biol. , vol.108 , pp. 45-55
    • Wang, Y.1    Toury, R.2    Hauchecorne, M.3    Balmain, N.4
  • 61
    • 0014125699 scopus 로고
    • A technique for the fixation and decalcification of rat incisors for electron microscopy
    • Warshawsky, H. and Moore, G. 1967. A technique for the fixation and decalcification of rat incisors for electron microscopy. J. Histochem. Cytochem., 15, 542-549.
    • (1967) J. Histochem. Cytochem. , vol.15 , pp. 542-549
    • Warshawsky, H.1    Moore, G.2
  • 62
  • 63
    • 85029462892 scopus 로고    scopus 로고
    • An effective in vivo model for osteoclast apoptosis
    • Wright, K.R. 1996. An effective in vivo model for osteoclast apoptosis. J. Bone Miner. Res., 11 (suppl 1), S397.
    • (1996) J. Bone Miner. Res. , vol.11 , Issue.1 SUPPL.
    • Wright, K.R.1
  • 64
    • 0030474221 scopus 로고    scopus 로고
    • Morphological and biochemical evidence for apoptosis in the terminal hypertrophic chondrocytes of the growth plate
    • Zenmyo, M., Komya, S., Kawabata, R., Yasuyuki, S., Inoue, A. and Morimatsu, M. 1996. Morphological and biochemical evidence for apoptosis in the terminal hypertrophic chondrocytes of the growth plate. J. Pathol., 180, 430-433.
    • (1996) J. Pathol. , vol.180 , pp. 430-433
    • Zenmyo, M.1    Komya, S.2    Kawabata, R.3    Yasuyuki, S.4    Inoue, A.5    Morimatsu, M.6
  • 65
    • 0027952812 scopus 로고
    • Occurrence of osteoblast necroses during ossification of long bone cortices in mouse fetuses
    • Zimmermann, B. 1994. Occurrence of osteoblast necroses during ossification of long bone cortices in mouse fetuses. Cell Tissue Res., 275, 345-353.
    • (1994) Cell Tissue Res. , vol.275 , pp. 345-353
    • Zimmermann, B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.