Chemical ribonucleases. 2. Design and hydrolytic activity of the ribonuclease mimics on the basis of diazabicyclo[2.2.2]octane with a differing number of positive charges

Bioorganicheskaya Khimiya

Volumn 26, Issue 9, 2000, Pages 679-685

  Zenkova, M A ^a   Vlassov, A V ^a   Konevets, D A ^a,b   Silnikov, V N ^b   Giege, R ^b   Vlassov, V V ^b  

^a ENERGY SYSTEMS INSTITUTE   (Russian Federation)

^b INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Artificial rnases; Enzyme active site modelling; Hydrolysis; RNA

Indexed keywords

FUSED HETEROCYCLIC RINGS; IMIDAZOLE DERIVATIVE; LYSINE TRANSFER RNA; MAGNESIUM; MONOVALENT CATION; RIBONUCLEASE;

ARTICLE; CATALYSIS; CHEMISTRY; DRUG DESIGN; GENETICS; HUMAN; HYDROLYSIS; MITOCHONDRION; MOLECULAR MIMICRY; POINT MUTATION; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

BICYCLO COMPOUNDS, HETEROCYCLIC; CATALYSIS; CATIONS, MONOVALENT; DRUG DESIGN; HUMANS; HYDROLYSIS; IMIDAZOLES; MAGNESIUM; MITOCHONDRIA; MOLECULAR MIMICRY; POINT MUTATION; RIBONUCLEASES; RNA, TRANSFER, LYS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0040748495     PISSN: 01323423     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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