Syntheses of imidazole-acridine conjugates as ribonuclease A mimics

Tetrahedron Letters

Volumn 37, Issue 25, 1996, Pages 4417-4420

  Lorente, Antonio ^a   Espinosa, Juan Félix ^a   Fernández Saiz, Misericordia ^a   Lehn, Jean Marie ^b   Wilson, W David ^c   Zhong, Yi Yi ^c  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b l'alimentation et l'Environnement   (France)

^c GEORGIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACRIDINE DERIVATIVE; IMIDAZOLE DERIVATIVE; INTERCALATING AGENT; PROFLAVINE; RIBONUCLEASE A; TRANSFER RNA;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CONJUGATE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; MOLECULAR RECOGNITION; RNA CLEAVAGE;

EID: 0029946227     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00843-X     Document Type: Article

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25. 4 1783.8)
26. 13 615.3).
27. 2N-acridine), 6.54 (s, 2H, H-5 imidazole), 6.94-7.38 (m, 35H, 3H acridine, 2H imidazole and 30H Ph-H), 7.62 (d, 1H, J= 8.79 Hz, H-8 acridine), 7.72 (d, 1H, J= 1.1 Hz, H-4 acridine), 7.80 (d, 1H, J= 9.16 Hz, H-1 acridine), 8.49 (s, 1H, H-9 acridine).
28. 8 412.2).