Searching for cyclazosin analogues as α1B-adrenoceptor antagonists

Farmaco

Volumn 58, Issue 7, 2003, Pages 477-487

  Giardinà, Dario ^a   Polimanti, O ^a   Sagratini, G ^a   Angeli, P ^a   Gulini, U ^a   Marucci, G ^a   Melchiorre, C ^b   Poggesi, E ^c   Leonardi, A ^c  

^a UNIVERSITY OF CAMERINO   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c Recordati SpA   (Italy)

Author keywords

Cyclazosin; Cyclazosin analogues; Quinazoline compounds; 1 Adrenoceptor antagonists; 1 Adrenoceptor subtypes

Indexed keywords

1 [4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINYL] 1 ETHANONE; 1 [4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINYL] 1 HEXANONE; 1 [4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINYL] 2 (2 ISOPROPYL 6 METHOXYPHENOXY) 1 ETHANONE; 1 [4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINYL] 2 (2,6 DIMETHOXYPHENYL) 1 ETHANONE; 1 [4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINYL] 2 (4 METHOXYPHENYL) 1 ETHANONE; 1 [4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINYL] 2 METHYL 1 PROPANONE; 1 [4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINYL] 2,2 DIMETHYL 1 PROPANONE; 1 [4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINYL] 3 PHENYL 2 PROPEN 1 ONE; 2 (4 METHYLPERHYDRO 1 QUINOXALINYL) 6,7 DIMETHOXY 4 QUINAZOLINAMINE; 2 [4 (4,6 DICHLORO 1,3,5 TRIAZIN 2 YL)PERHYDRO 1 QUINOXALINYL] 6,7 DIMETHOXY 4 QUINAZOLINAMINE; 2 [4 (4,6 DIMETHOXY 1,3,5 TRIAZIN 2 YL)PERHYDRO 1 QUINOXALINYL] 6,7 DIMETHOXY 4 QUINAZOLINAMINE; 6,7 DIMETHOXY 2 PERHYDRO 1 QUINOXALINYL 4 QUINAZOLINAMINE; ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1B ADRENERGIC RECEPTOR; BENZYL 4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINE CARBOXYLATE; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG; [4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINYL] (3,4 DIHYDRO 2H 2 CHROMENYL)METHANONE; [4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINYL](2 NAPHTHYL) 1 ETHANONE; [4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINYL](5 METHYL 2 FURYL)METHANONE; [4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINYL](CYCLOHEXYL)METHANONE; [4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINYL](PHENYL)METHANONE; [4 (4 AMINO 6,7 DIMETHOXY 2 QUINAZOLINYL)PERHYDRO 1 QUINOXALINYL](TETRAHYDRO 2 FURANYL)METHANONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; GUINEA PIG; HUMAN; MALE; NONHUMAN; RAT;

EID: 0038798618     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(02)00025-3     Document Type: Article

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