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Volumn 12, Issue 7, 2003, Pages 1165-1177

Therapeutic potential of the new quinolones in the treatment of lower respiratory tract infections

Author keywords

Antimicrobial resistance; Community acquired respiratory infections; Fluoroquinolones; Pharmacokinetic

Indexed keywords

ALUMINUM; AMOXICILLIN PLUS CLAVULANIC ACID; ANTIINFECTIVE AGENT; AZITHROMYCIN; CEFACLOR; CEFTRIAXONE; CEFUROXIME AXETIL; CEPHALOSPORIN DERIVATIVE; CIPROFLOXACIN; CLARITHROMYCIN; CLINDAMYCIN; DIGOXIN; GARENOXACIN; GATIFLOXACIN; GEMIFLOXACIN; IRON; LEVOFLOXACIN; MACROLIDE; MAGNESIUM; METICILLIN; METRONIDAZOLE; MOXIFLOXACIN; PENICILLIN G; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SITAFLOXACIN; THEOPHYLLINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; WARFARIN; ZINC;

EID: 0038783384     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.12.7.1165     Document Type: Review
Times cited : (14)

References (83)
  • 1
    • 0032784460 scopus 로고    scopus 로고
    • Structures of existing and new quinolones and relationship to bactericidal activity against Streptococcus pneumoniae
    • MITSUYAMA J: Structures of existing and new quinolones and relationship to bactericidal activity against Streptococcus pneumoniae. J. Antimicrob. Chemother. (1999) 44:201-207.
    • (1999) J. Antimicrob. Chemother. , vol.44 , pp. 201-207
    • Mitsuyama, J.1
  • 2
    • 0033979885 scopus 로고    scopus 로고
    • Engineering the specificity of antibacterial fluoroquinolones: Benzenesulfonamide modifications at C-7 of ciprofloxacin change its primary target in Streptococcus pneumoniae from topoisometase IV to gyrase
    • ALOVERO F, PAN X-S, MORRIS JE, MANZO RH, FISHER LM: Engineering the specificity of antibacterial fluoroquinolones: benzenesulfonamide modifications at C-7 of ciprofloxacin change its primary target in Streptococcus pneumoniae from topoisometase IV to gyrase. Antimicrob. Agents Chemother. (2000) 44:320-325.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 320-325
    • Alovero, F.1    Pan, X.-S.2    Morris, J.E.3    Manzo, R.H.4    Fisher, L.M.5
  • 3
    • 15444352824 scopus 로고    scopus 로고
    • Relationship between ciprofloxacin, ofloxacin, levofloxacin, sparfloxacin and moxifloxacin (BAY 12-8039) MICs and mutations in grlA, grlB, gyrA and gyrB in 116 unrelated clinical isolates of Staphylococcus aureus
    • SCHMITZ FJ, HOFMANN B, HANSEN B et al.: Relationship between ciprofloxacin, ofloxacin, levofloxacin, sparfloxacin and moxifloxacin (BAY 12-8039) MICs and mutations in grlA, grlB, gyrA and gyrB in 116 unrelated clinical isolates of Staphylococcus aureus. J. Antimicrob. Chemother. (1998) 41:481-484.
    • (1998) J. Antimicrob. Chemother. , vol.41 , pp. 481-484
    • Schmitz, F.J.1    Hofmann, B.2    Hansen, B.3
  • 4
    • 0035043010 scopus 로고    scopus 로고
    • The chemical and biological aspects of fluoroquinolones: Reality and dreams
    • CHANT SK, SINGH M, CHATTERJEE NR: The chemical and biological aspects of fluoroquinolones: reality and dreams. Curr. Pharm. Design (2001) 7:313-337.
    • (2001) Curr. Pharm. Design , vol.7 , pp. 313-337
    • Chant, S.K.1    Singh, M.2    Chatterjee, N.R.3
  • 5
    • 0036221654 scopus 로고    scopus 로고
    • Pharmacokynetic and pharmacodynamic predictors of antimicrobial efficacy: Moxifloxacin and Streptococcus pneumoniae
    • SCHENTAG JJ: Pharmacokynetic and pharmacodynamic predictors of antimicrobial efficacy: Moxifloxacin and Streptococcus pneumoniae. J. Chemother. (2002) 14(S2):13-21.
    • (2002) J. Chemother. , vol.14 , Issue.SUPPL. 2 , pp. 13-21
    • Schentag, J.J.1
  • 6
    • 0037394320 scopus 로고    scopus 로고
    • 0-t/MIC is a continuous index of fluoroquinolone exposure and predictive of antibacterial response for Streptococcus pneumoniae in an in vitro infection model
    • 0-t/MIC is a continuous index of fluoroquinolone exposure and predictive of antibacterial response for Streptococcus pneumoniae in an in vitro infection model. J. Antimicrob. Chemother. (2003) 51:905-911.
    • (2003) J. Antimicrob. Chemother. , vol.51 , pp. 905-911
    • Zelenitsky, S.A.1    Ariano, R.E.2    Iacovides, H.3    Sun, S.4    Harding, G.K.M.5
  • 7
    • 0036733450 scopus 로고    scopus 로고
    • Efficacy and pharmacodynamic of simulated human-like treatment with levofloxacin on experimental pneumonia induced with penicillin-resistant pneumococci with various susceptibilities to fluoroquinolones
    • CROISIER D, CHAVANET P, LEQUEU C et al.: Efficacy and pharmacodynamic of simulated human-like treatment with levofloxacin on experimental pneumonia induced with penicillin-resistant pneumococci with various susceptibilities to fluoroquinolones. J. Antimicrob. Chemother. (2002) 50:349-360.
    • (2002) J. Antimicrob. Chemother. , vol.50 , pp. 349-360
    • Croisier, D.1    Chavanet, P.2    Lequeu, C.3
  • 8
    • 0032971470 scopus 로고
    • Expanded activity and utility of the new fluorquinolones: A review
    • BLONDEAU JM: Expanded activity and utility of the new fluorquinolones: a review. Clin. Ther. (1991) 21:3-40.
    • (1991) Clin. Ther. , vol.21 , pp. 3-40
    • Blondeau, J.M.1
  • 9
    • 0034130064 scopus 로고    scopus 로고
    • Age and Gender effects on the pharmacokinetics of gatifloxacin
    • LACRETA FP, KOLLIA GD, DUNCAN G et al.: Age and Gender effects on the pharmacokinetics of gatifloxacin. Pharmacotherapy (2000) 20:67S-75S.
    • (2000) Pharmacotherapy , vol.20
    • Lacreta, F.P.1    Kollia, G.D.2    Duncan, G.3
  • 10
    • 0030790098 scopus 로고    scopus 로고
    • Absence of age and gender effects on the pharmacokinetics of a single 500-milligram oral does of levofloxacin in healthy subjects
    • CHIEN SC, CHOW AT, NATARAJAN J et al.: Absence of age and gender effects on the pharmacokinetics of a single 500-milligram oral does of levofloxacin in healthy subjects. Antimicrob. Agents Chemother. (1997) 41:1562-1565.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 1562-1565
    • Chien, S.C.1    Chow, A.T.2    Natarajan, J.3
  • 11
    • 0034089387 scopus 로고    scopus 로고
    • Moxifloxacin, a new antibiotic designed to treat community-acquired respiratory tract infections: A review of microbiologic and pharmacokinetic-pharmacodynamic characteristics
    • NIGHTINGALE CH: Moxifloxacin, a new antibiotic designed to treat community-acquired respiratory tract infections: a review of microbiologic and pharmacokinetic-pharmacodynamic characteristics. Pharmacotherapy (2000) 20:245-256.
    • (2000) Pharmacotherapy , vol.20 , pp. 245-256
    • Nightingale, C.H.1
  • 13
    • 0032897244 scopus 로고    scopus 로고
    • Pharmacodynamics of fluoroquinolones
    • DALHOFF A: Pharmacodynamics of fluoroquinolones. J. Antimicrob. Chemother. (1999) 43(Suppl. B):51-59.
    • (1999) J. Antimicrob. Chemother. , vol.43 , Issue.SUPPL. B , pp. 51-59
    • Dalhoff, A.1
  • 14
    • 0033836018 scopus 로고    scopus 로고
    • Mutant prevention concentration as a measure of antibiotic potency: Studies with clinical isolates of Mycobacterium tuberculosis
    • DONG Y, ZHAO X, KREISWIRTH B et al.: Mutant prevention concentration as a measure of antibiotic potency: studies with clinical isolates of Mycobacterium tuberculosis. Antimicrob. Agents Chemother. (2000) 44:1756-1758.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 1756-1758
    • Dong, Y.1    Zhao, X.2    Kreiswirth, B.3
  • 15
    • 0035139520 scopus 로고    scopus 로고
    • Mutant prevention concentrations (MPC) for fluoroquinolones with clinical isolates of Streptococcus pneumoniae
    • BLONDEAU J, ZHAO X, HANSEN G et al.: Mutant prevention concentrations (MPC) for fluoroquinolones with clinical isolates of Streptococcus pneumoniae. Antimicrob. Agents Chemotber. (2001) 45:433-438.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 433-438
    • Blondeau, J.1    Zhao, X.2    Hansen, G.3
  • 16
    • 0037416984 scopus 로고    scopus 로고
    • Mutant prevention concentration of garenoxacin for ciprofloxacin-susceptible or -resistant Staphylococcus aureus
    • ZHAO X, EISNER W, PERL-ROSENTHAL N, KREISWIRTH B, DRLICA K: Mutant prevention concentration of garenoxacin for ciprofloxacin-susceptible or -resistant Staphylococcus aureus. Antimicrob. Agents Chemother. (2003) 47:1023-1027.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 1023-1027
    • Zhao, X.1    Eisner, W.2    Perl-Rosenthal, N.3    Kreiswirth, B.4    Drlica, K.5
  • 17
    • 0037492258 scopus 로고    scopus 로고
    • Garenoxacin (BMS284756) activity against 8,686 S. pneumoniae including tentative susceptibility testing criteria
    • 42nd ICAAC, San Diego, CA, USA (Abstract E58)
    • JONES RN, MUTNICK A, BIEDENBACH D: Garenoxacin (BMS284756) activity against 8,686 S. pneumoniae including tentative susceptibility testing criteria. 42nd ICAAC, San Diego, CA, USA (2002):151 (Abstract E58).
    • (2002) , pp. 151
    • Jones, R.N.1    Mutnick, A.2    Biedenbach, D.3
  • 18
    • 0037829769 scopus 로고    scopus 로고
    • Activity of BMS284756 and marketed fluoroquinolones against lower respiratory tract pathogens: Results of a 3 year Canadian Surveillance study
    • 42nd ICAAC, San Diego, CA, USA (Abstract E64)
    • HOBAN DJ, PALATNICK L, SMITH H, NICHOL K, HOBAN C, ZHANEL GG: Activity of BMS284756 and marketed fluoroquinolones against lower respiratory tract pathogens: results of a 3 year Canadian Surveillance study. 42nd ICAAC, San Diego, CA, USA (2002):153 (Abstract E64).
    • (2002) , pp. 153
    • Hoban, D.J.1    Palatnick, L.2    Smith, H.3    Nichol, K.4    Hoban, C.5    Zhanel, G.G.6
  • 19
    • 0013163602 scopus 로고    scopus 로고
    • Activity of DK507k, a new fluoroquinolone, against quinolone non-susceptible Streptococcus pneumoniae compared to ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin and sitafloxacin
    • 42nd ICAAC, San Diego, CA, USA (Abstract F571)
    • BOZDOGAN B, KELLY L, JACOBS MR, APPELBAUM PC: Activity of DK507k, a new fluoroquinolone, against quinolone non-susceptible Streptococcus pneumoniae compared to ciprofloxacin, levofloxacin, moxifloxacin, gatifloxacin and sitafloxacin. 42nd ICAAC, San Diego, CA, USA (2002):189 (Abstract F571).
    • (2002) , pp. 189
    • Bozdogan, B.1    Kelly, L.2    Jacobs, M.R.3    Appelbaum, P.C.4
  • 20
    • 0013122849 scopus 로고    scopus 로고
    • Time-kill study of antipneumococcal activity of DK507k, a new fluoroquinolone, compared to 5 other agents
    • 42nd ICAAC, San Diego CA, USA (Abstract F574)
    • CLARK CL, JACOBS MR, APPELBAUM PC: Time-kill study of antipneumococcal activity of DK507k, a new fluoroquinolone, compared to 5 other agents. 42nd ICAAC, San Diego CA, USA (2002):190 (Abstract F574).
    • (2002) , pp. 190
    • Clark, C.L.1    Jacobs, M.R.2    Appelbaum, P.C.3
  • 21
    • 0013169549 scopus 로고    scopus 로고
    • Time-kill analysis of the antipneumococcal activity of two new quinolones, WCK771A and WCK919, compared to five other quinolones
    • 42nd ICAAC, San Diego CA, USA (Abstract F559)
    • LIN G, PATEL M, GUPTE S et al.: Time-kill analysis of the antipneumococcal activity of two new quinolones, WCK771A and WCK919, compared to five other quinolones. 42nd ICAAC, San Diego CA, USA (2002):186 (Abstract F559).
    • (2002) , pp. 186
    • Lin, G.1    Patel, M.2    Gupte, S.3
  • 22
    • 0038184157 scopus 로고    scopus 로고
    • In vitro antibacterial activity and pharmacodynamics of new quinolones
    • DALHOFF A, SCHMITZ FJ: In vitro antibacterial activity and pharmacodynamics of new quinolones. Eur. J. Clin. Microbiol. Infect. Dis. (2003) 22:203-221.
    • (2003) Eur. J. Clin. Microbiol. Infect. Dis. , vol.22 , pp. 203-221
    • Dalhoff, A.1    Schmitz, F.J.2
  • 23
    • 0035663066 scopus 로고    scopus 로고
    • Comparative in vitro potency of gemifloxacin and fluoroquinolones against recent european clinical isolates from a global surveillance study
    • HOBAN DJ, BOUCHILLON SK, JOHNSON JL et al.: Comparative in vitro potency of gemifloxacin and fluoroquinolones against recent european clinical isolates from a global surveillance study. Eur. J. Clin. Microbiol. Infect. Dis. (2001) 20:814-819.
    • (2001) Eur. J. Clin. Microbiol. Infect. Dis. , vol.20 , pp. 814-819
    • Hoban, D.J.1    Bouchillon, S.K.2    Johnson, J.L.3
  • 24
    • 0038506163 scopus 로고    scopus 로고
    • In vitro activity of ABT 492 versus quinolones and macrolides against Legionella spp
    • 42nd ICAAC, San Diego, CA, USA (Abstract F553)
    • DUBOIS J, ST-PIERRE C: In vitro activity of ABT 492 versus quinolones and macrolides against Legionella spp. 42nd ICAAC, San Diego, CA, USA (2002):185 (Abstract F553).
    • (2002) , pp. 185
    • Dubois, J.1    St-Pierre, C.2
  • 25
    • 0034102922 scopus 로고    scopus 로고
    • In vitro activities of sitafloxacin and six other quinolones against 8.796 clinical bacterial isolates
    • MILATOVICH D, SCHMITZ FJ, BRISSE S, VERHOEF J, FLUIT AC: In vitro activities of sitafloxacin and six other quinolones against 8.796 clinical bacterial isolates. Antimicrob. Agents Chemother. (2000) 44:1102-1107.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 1102-1107
    • Milatovich, D.1    Schmitz, F.J.2    Brisse, S.3    Verhoef, J.4    Fluit, A.C.5
  • 26
    • 0028301106 scopus 로고
    • Increased activity of a new chlorofluoroquinolone, BAY y3118, compared with activities of ciprofloxacin, sparfloxacin, and other antimicrobial agents against anaerobic bacteria
    • ALDRIDGE KE: Increased activity of a new chlorofluoroquinolone, BAY y3118, compared with activities of ciprofloxacin, sparfloxacin, and other antimicrobial agents against anaerobic bacteria. Antimicrob. Agents Chemother. (1994) 38:1671-1674.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 1671-1674
    • Aldridge, K.E.1
  • 27
    • 0037492257 scopus 로고    scopus 로고
    • Anti-anaerobic activity of two new quinolones, WCK771A and WCK919, compared to nine other agents
    • 42nd ICAAC, San Diego, CA, USA (Abstract F561)
    • APPELBAUM PC, PATEL M, GUPTE S et al.: Anti-anaerobic activity of two new quinolones, WCK771A and WCK919, compared to nine other agents. 42nd ICAAC, San Diego, CA, USA (2002):187 (Abstract F561).
    • (2002) , pp. 187
    • Appelbaum, P.C.1    Patel, M.2    Gupte, S.3
  • 28
    • 0032973962 scopus 로고    scopus 로고
    • Clinical effectiveness of levofloxacin in patients with acute purulent exacerbations of chronic bronchitis: The relationship with in-vitro activity
    • DAVIES BI, MAESEN FP: Clinical effectiveness of levofloxacin in patients with acute purulent exacerbations of chronic bronchitis: the relationship with in-vitro activity. J. Antimicrob. Chemother. (1999) 43(Suppl. C):83-90.
    • (1999) J. Antimicrob. Chemother. , vol.43 , Issue.SUPPL. C , pp. 83-90
    • Davies, B.I.1    Maesen, F.P.2
  • 29
    • 0031024361 scopus 로고    scopus 로고
    • Safety and efficacy of oral levofloxacin versus cefuroxime axetil in acute bacterial exacerbations of chronic bronchitis
    • DE ABATE CA, RUSSEL M, MCELVAINE P et al.: Safety and efficacy of oral levofloxacin versus cefuroxime axetil in acute bacterial exacerbations of chronic bronchitis. Respir. Care (1997) 42:206-213.
    • (1997) Respir. Care , vol.42 , pp. 206-213
    • De Abate, C.A.1    Russel, M.2    McElvaine, P.3
  • 30
    • 0031934272 scopus 로고    scopus 로고
    • Multicenter, randomized study comparing efficacy and safety of oral levofloxacin and cefaclor in the treatment of acute exacerbations of chronic bronchitis
    • HABIB MP, RUSSELL M, DE ABATE CA et al.: Multicenter, randomized study comparing efficacy and safety of oral levofloxacin and cefaclor in the treatment of acute exacerbations of chronic bronchitis. Infect. Dis. Clin. Practice (1998) 7:1-9.
    • (1998) Infect. Dis. Clin. Practice , vol.7 , pp. 1-9
    • Habib, M.P.1    Russell, M.2    DeAbate, C.A.3
  • 31
    • 0032909077 scopus 로고    scopus 로고
    • Levofloxacin versus cefuroxime axetil in the treatment of acute exacerbations of chronic bronchitis: Results of a randomized, double-blind study
    • SHAH PM, MAESEN FP, DOLMANN A et al.: Levofloxacin versus cefuroxime axetil in the treatment of acute exacerbations of chronic bronchitis: results of a randomized, double-blind study. J. Antimicrob. Chemother. (1999) 43:529-539.
    • (1999) J. Antimicrob. Chemother. , vol.43 , pp. 529-539
    • Shah, P.M.1    Maesen, F.P.2    Dolmann, A.3
  • 32
    • 0036749773 scopus 로고    scopus 로고
    • Open-label, randomized comparison of the efficacy and tolerability of clarithromycin, levofloxacin, and cefuroxime axetil in the treatment of adults with acute bacterial exacerbations of chronic bronchitis
    • WEISS LR: Open-label, randomized comparison of the efficacy and tolerability of clarithromycin, levofloxacin, and cefuroxime axetil in the treatment of adults with acute bacterial exacerbations of chronic bronchitis. Clin. Ther. (2002) 24:1414-1425.
    • (2002) Clin. Ther. , vol.24 , pp. 1414-1425
    • Weiss, L.R.1
  • 33
    • 0035216957 scopus 로고    scopus 로고
    • Randomized, double-blind study comparing 5- and 7-day regimens of oral levofloxacin in patients with acute exacerbations of chronic bronchitis
    • MASTERTON RG, BURLEY CJ: Randomized, double-blind study comparing 5- and 7-day regimens of oral levofloxacin in patients with acute exacerbations of chronic bronchitis. Int. J. Antimicrob. Agents (2001) 18:503-512.
    • (2001) Int. J. Antimicrob. Agents , vol.18 , pp. 503-512
    • Masterton, R.G.1    Burley, C.J.2
  • 34
    • 0002232777 scopus 로고    scopus 로고
    • Gatifloxacin treatment in patients with acute exacerbations of chronic bronchitis: Clinical trial results
    • RAMIREZ A, MOLINA J, HOFMANN A et al.: Gatifloxacin treatment in patients with acute exacerbations of chronic bronchitis: clinical trial results. J. Respir. Dis. (1999) 20(11):30s-39s.
    • (1999) J. Respir. Dis. , vol.20 , Issue.11
    • Ramirez, A.1    Molina, J.2    Hofmann, A.3
  • 35
    • 0003045972 scopus 로고    scopus 로고
    • Gatifloxacin versus cefuroxime axetil in patients with acute exacerbations of chronic bronchitis
    • DE ABATE CA, MCIVOR RA, MCELVAINE P et al.: Gatifloxacin versus cefuroxime axetil in patients with acute exacerbations of chronic bronchitis. J. Respir. Dis. (1999) 20(11):23s-29s.
    • (1999) J. Respir. Dis. , vol.20 , Issue.11
    • DeAbate, C.A.1    Mcivor, R.A.2    McElvaine, P.3
  • 36
    • 0032835722 scopus 로고    scopus 로고
    • Five day moxifloxacin therapy compared with 7 day clarithromycin therapy for the treatment of acute exacerbations of chronic bronchitis
    • WILSON R, KUBIN R, BALLIN I et al.: Five day moxifloxacin therapy compared with 7 day clarithromycin therapy for the treatment of acute exacerbations of chronic bronchitis. J. Antimicrob. Chemother. (1999) 44:501-513.
    • (1999) J. Antimicrob. Chemother. , vol.44 , pp. 501-513
    • Wilson, R.1    Kubin, R.2    Ballin, I.3
  • 37
    • 0033994809 scopus 로고    scopus 로고
    • Short-course moxifloxacin therapy for treatment of acute bacterial exacerbations of chronic bronchitis
    • The Bronchitis Study Group
    • CHODOSH S, DEABATE CA, HAVERSTOCK D et al.: Short-course moxifloxacin therapy for treatment of acute bacterial exacerbations of chronic bronchitis. The Bronchitis Study Group. Respir. Med. (2000) 94:18-27.
    • (2000) Respir. Med. , vol.94 , pp. 18-27
    • Chodosh, S.1    Deabate, C.A.2    Haverstock, D.3
  • 38
    • 0002656489 scopus 로고    scopus 로고
    • A comparison of moxifloxacin and azithromycin in the treatment of acute exacerbations of chronic bronchitis
    • KREIS S, HERRERA N, GOLZAR N et al.: A comparison of moxifloxacin and azithromycin in the treatment of acute exacerbations of chronic bronchitis. J. Clin. Outcomes Manage. (2000) 7:3337.
    • (2000) J. Clin. Outcomes Manage. , vol.7 , pp. 3337
    • Kreis, S.1    Herrera, N.2    Golzar, N.3
  • 39
    • 0033652111 scopus 로고    scopus 로고
    • The safety and efficacy of short course (5-day) moxifloxacin versus azithromycin in the treatment of patients with acute exacerbations of chronic bronchitis
    • DEABATE CA, MATTHEW CP, WARNER JH et al.: The safety and efficacy of short course (5-day) moxifloxacin versus azithromycin in the treatment of patients with acute exacerbations of chronic bronchitis. Respir. Med. (2000) 94:1029-1037.
    • (2000) Respir. Med. , vol.94 , pp. 1029-1037
    • Deabate, C.A.1    Matthew, C.P.2    Warner, J.H.3
  • 40
    • 0034811145 scopus 로고    scopus 로고
    • A multinational, multicentre, non-blinded, randomized study of moxifloxacin oral tablets compared with co-amoxiclav oral tablets in the treatment of acute exacerbations of chronic bronchitis
    • SCHABERG T, BALLIN I, HUCHON G et al.: A multinational, multicentre, non-blinded, randomized study of moxifloxacin oral tablets compared with co-amoxiclav oral tablets in the treatment of acute exacerbations of chronic bronchitis. J. Int. Med. Res. (2001) 29:314-328.
    • (2001) J. Int. Med. Res. , vol.29 , pp. 314-328
    • Schaberg, T.1    Ballin, I.2    Huchon, G.3
  • 41
    • 0035017628 scopus 로고    scopus 로고
    • Treatment outcomes in acute exacerbations of chronic bronchitis: Comparison of macrolides and moxifloxacin from the patient perspective
    • LORENZ J, THATE-WASCHKE IM, MAST O et al.: Treatment outcomes in acute exacerbations of chronic bronchitis: comparison of macrolides and moxifloxacin from the patient perspective. J. Int. Med. Res. (2001) 29:74-86.
    • (2001) J. Int. Med. Res. , vol.29 , pp. 74-86
    • Lorenz, J.1    Thate-Waschke, I.M.2    Mast, O.3
  • 42
    • 0343852343 scopus 로고    scopus 로고
    • A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in the treatment of adults with community-acquired pneumonia
    • FILE TM, SEGRETI J, DUBAR L et al.: A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in the treatment of adults with community-acquired pneumonia. Antimicrob. Agents Chemother. (1997) 41:1965-1972.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 1965-1972
    • File, T.M.1    Segreti, J.2    Dubar, L.3
  • 43
    • 0032761897 scopus 로고    scopus 로고
    • Levofloxacin in the empirical treatment of patients with suspected bacteraemia/sepsis: Comparison with imipenem/cilastatin in an open, randomised trial
    • GEDDES AM, THALER M, SCHONWALD S et al.: Levofloxacin in the empirical treatment of patients with suspected bacteraemia/sepsis: comparison with imipenem/cilastatin in an open, randomised trial. J. Antimicrob. Chemother. (1999) 44:799-810.
    • (1999) J. Antimicrob. Chemother. , vol.44 , pp. 799-810
    • Geddes, A.M.1    Thaler, M.2    Schonwald, S.3
  • 44
    • 0001797459 scopus 로고    scopus 로고
    • Treating community-acquired pneumonia with once daily gatifloxacin versus once daily levofloxacin
    • SULLIVAN J, MCELROY AD, HONSINGER RW et al.: Treating community-acquired pneumonia with once daily gatifloxacin versus once daily levofloxacin. J. Respir. Dis. (1999) 20(S11):49s-59s.
    • (1999) J. Respir. Dis. , vol.20 , Issue.SUPPL. 11
    • Sullivan, J.1    MCelroy, A.D.2    Honsinger, R.W.3
  • 45
    • 0001797458 scopus 로고    scopus 로고
    • Treating community-acquired pneumonia with once daily gatifloxacin versus twice daily clarithromycin
    • RAMIREZ JA, NGUYEN TH, TELLIER G et al.: Treating community-acquired pneumonia with once daily gatifloxacin versus twice daily clarithromycin. J. Respir. Dis. (1999) 20(S11):40s-48s.
    • (1999) J. Respir. Dis. , vol.20 , Issue.SUPPL. 11
    • Ramirez, J.A.1    Nguyen, T.H.2    Tellier, G.3
  • 46
    • 0001797457 scopus 로고    scopus 로고
    • Treating community-acquired pneumonia in hospitalised patients: Gatifloxacin versus ceftriaxone/clarithromycin
    • FOGARTY C, DOWELL ME, ELLISON WT et al.: Treating community-acquired pneumonia in hospitalised patients: gatifloxacin versus ceftriaxone/clarithromycin. J. Respir. Dis. (1999) 20(S11):S60-S69.
    • (1999) J. Respir. Dis. , vol.20 , Issue.SUPPL. 11
    • Fogarty, C.1    Dowell, M.E.2    Ellison, W.T.3
  • 47
    • 0034934856 scopus 로고    scopus 로고
    • Cost-effectiveness of gatifloxacin versus ceftriaxone with a macrolide for the treatment of community-acquired pneumonia
    • DRESSER LD, NIEDERMAN MS, PALADINO JA: Cost-effectiveness of gatifloxacin versus ceftriaxone with a macrolide for the treatment of community-acquired pneumonia. Chest (2001) 119:1439-1448.
    • (2001) Chest , vol.119 , pp. 1439-1448
    • Dresser, L.D.1    Niederman, M.S.2    Paladino, J.A.3
  • 48
    • 0032723032 scopus 로고    scopus 로고
    • Efficacy and safety of moxifloxacin versus clarithromycin for community-acquired pneumonia
    • FOGARTY C, GROSSMAN C, WILLIAMS J et al.: Efficacy and safety of moxifloxacin versus clarithromycin for community-acquired pneumonia. Infect. Med. (1999) 16:748-763.
    • (1999) Infect. Med. , vol.16 , pp. 748-763
    • Fogarty, C.1    Grossman, C.2    Williams, J.3
  • 49
    • 0034933394 scopus 로고    scopus 로고
    • The efficacy and safety of two oral moxifloxacin regimens compared to oral clarithromycin in the treatment of community-acquired pneumonia
    • HOEFFKEN G, MEYER HP, WINTER J et al.: The efficacy and safety of two oral moxifloxacin regimens compared to oral clarithromycin in the treatment of community-acquired pneumonia. Respir. Med. (2001) 95:553-564.
    • (2001) Respir. Med. , vol.95 , pp. 553-564
    • Hoeffken, G.1    Meyer, H.P.2    Winter, J.3
  • 50
    • 17744397528 scopus 로고    scopus 로고
    • Oral moxifloxacin versus high-dosage amoxicillin in the treatment of mild-to-moderate, community-acquired, suspected pneumococcal pneumonia in adults
    • PETITPRETZ P, ARVIS P, MARCEL M et al.: Oral moxifloxacin versus high-dosage amoxicillin in the treatment of mild-to-moderate, community-acquired, suspected pneumococcal pneumonia in adults. Chest (2001) 119:185-195.
    • (2001) Chest , vol.119 , pp. 185-195
    • Petitpretz, P.1    Arvis, P.2    Marcel, M.3
  • 51
    • 0038167457 scopus 로고    scopus 로고
    • Randomized controlled trial of sequential intravenous (i.v.) and oral moxifloxacin compared to sequential i.v and oral co-amoxiclav with or without clarithromycin in patients with community-acquired pneumonia requiring initial parenteral treatment
    • FINCH R, SCHURMANN D, COLLINS O et al.: Randomized controlled trial of sequential intravenous (i.v.) and oral moxifloxacin compared to sequential i.v and oral co-amoxiclav with or without clarithromycin in patients with community-acquired pneumonia requiring initial parenteral treatment. Drugs (2002) 62:13-59.
    • (2002) Drugs , vol.62 , pp. 13-59
    • Finch, R.1    Schurmann, D.2    Collins, O.3
  • 52
    • 0030666474 scopus 로고    scopus 로고
    • Concentration of levofloxacin in the respiratory tract following a single oral doses in patients undergoing fibre-optic bronchoscopy
    • ANDREWS JM, HONEYBOURNE, D, JEVONS G, BRENWALD NP, CUNNINGHAM B, WISE R: Concentration of levofloxacin in the respiratory tract following a single oral doses in patients undergoing fibre-optic bronchoscopy. J. Antimicrob. Chemother. (1997) 40:573-577.
    • (1997) J. Antimicrob. Chemother. , vol.40 , pp. 573-577
    • Andrews, J.M.1    Honeybourne, D.2    Jevons, G.3    Brenwald, N.P.4    Cunningham, B.5    Wise, R.6
  • 54
    • 0032860774 scopus 로고    scopus 로고
    • Will pneumococci put quinolones in their place
    • LEGG JM, BINT AJ: Will pneumococci put quinolones in their place. J. Antimicrob. Chemother. (1999) 44:425-427.
    • (1999) J. Antimicrob. Chemother. , vol.44 , pp. 425-427
    • Legg, J.M.1    Bint, A.J.2
  • 55
    • 0033595136 scopus 로고    scopus 로고
    • Decreased susceptibility of Sheptococcus pneumoniae to fluoroquinolones in Canada
    • CHEN DK, MCGEER A, DE AZAVEDO JC, LOW DE: Decreased susceptibility of Sheptococcus pneumoniae to fluoroquinolones in Canada. N. Engl. J. Med. (1999) 341:233-239.
    • (1999) N. Engl. J. Med. , vol.341 , pp. 233-239
    • Chen, D.K.1    McGeer, A.2    De Azavedo, J.C.3    Low, D.E.4
  • 56
    • 0036178134 scopus 로고    scopus 로고
    • A critical review of the fluoroquinolones: Focus on respiratory tract infections
    • ZHANEL GG, EMIS K, VERCAINGE L et al.: A critical review of the fluoroquinolones: focus on respiratory tract infections. Drugs (2002) 62:13-59.
    • (2002) Drugs , vol.62 , pp. 13-59
    • Zhanel, G.G.1    Emis, K.2    Vercainge, L.3
  • 57
    • 0037240273 scopus 로고    scopus 로고
    • Maintaining fluoroquinolone class efficacy: Review of influencing factors
    • SCHELD WM: Maintaining fluoroquinolone class efficacy: review of influencing factors. Emerg. Infect. Dis. (2003) 9:1-9.
    • (2003) Emerg. Infect. Dis. , vol.9 , pp. 1-9
    • Scheld, W.M.1
  • 58
    • 0035189079 scopus 로고    scopus 로고
    • Increasing resistance of S. pneumoniae to fluoroquinolones: Results of a Hong Kong multicentre study in 2000
    • HO PL, YUNG RW, TSANG DN et al.: Increasing resistance of S. pneumoniae to fluoroquinolones: results of a Hong Kong multicentre study in 2000. J. Antimicrob. Chemother. (2001) 48:659-665.
    • (2001) J. Antimicrob. Chemother. , vol.48 , pp. 659-665
    • Ho, P.L.1    Yung, R.W.2    Tsang, D.N.3
  • 59
    • 0034999522 scopus 로고    scopus 로고
    • Antimicrobial resistance among clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000, including a comparison of resistance since 1994-1995
    • DOERN GV, HEILMANN KP, HUYNH HK, RHOMBERG PL, COFFMAN SL, BRUEGGEMANN AB: Antimicrobial resistance among clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000, including a comparison of resistance since 1994-1995. Antimicrob. Agents Chemother. (2001) 45:1721-1729.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 1721-1729
    • Doern, G.V.1    Heilmann, K.P.2    Huynh, H.K.3    Rhomberg, P.L.4    Coffman, S.L.5    Brueggemann, A.B.6
  • 60
    • 0034769363 scopus 로고    scopus 로고
    • Guidelines for the management of community-acquired pneumonia
    • NIEDERMAN MS: Guidelines for the management of community-acquired pneumonia. Med. Clin. North Am. (2001) 85:1493-1509.
    • (2001) Med. Clin. North Am. , vol.85 , pp. 1493-1509
    • Niederman, M.S.1
  • 61
    • 0033029687 scopus 로고    scopus 로고
    • Primary targets of fluoroquinolones in Streptococcus pneumoniae
    • FUKUDA H, HIRAMATSU K: Primary targets of fluoroquinolones in Streptococcus pneumoniae. Antimicrob. Agents Chemother. (1999) 43:410-412.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 410-412
    • Fukuda, H.1    Hiramatsu, K.2
  • 62
    • 0029160818 scopus 로고
    • Mechanisms of resistance to fluoroquinolones: State ofthe art 1992-1994
    • PIDDOCK LJ: Mechanisms of resistance to fluoroquinolones: state ofthe art 1992-1994. Drugs (1995) 49(2):29-35.
    • (1995) Drugs , vol.49 , Issue.2 , pp. 29-35
    • Piddock, L.J.1
  • 63
    • 0035038683 scopus 로고    scopus 로고
    • Emerging mechanisms of fluoroquinolone resistance
    • HOOPER DC: Emerging mechanisms of fluoroquinolone resistance. Emerg. Infect. Dis. (2001) 7:337-341.
    • (2001) Emerg. Infect. Dis. , vol.7 , pp. 337-341
    • Hooper, D.C.1
  • 64
    • 0033081949 scopus 로고    scopus 로고
    • Mechanism of quinolone resistance
    • HOOPER DC: Mechanism of quinolone resistance. Drug Resistance Updates (1999) 2:38-55.
    • (1999) Drug Resistance Updates , vol.2 , pp. 38-55
    • Hooper, D.C.1
  • 65
    • 0002892367 scopus 로고    scopus 로고
    • Bacterial resistance to quinolones
    • (2nd Ed.). VT Andriole (Ed.), Academic Press, San Diego, CA, USA
    • KÖHLER T, PECHÈRE JC: Bacterial resistance to quinolones. In: The Quinolones (2nd Ed.). VT Andriole (Ed.), Academic Press, San Diego, CA, USA (1998):117-142.
    • (1998) The Quinolones , pp. 117-142
    • Köhler, T.1    Pechère, J.C.2
  • 66
    • 0036800213 scopus 로고    scopus 로고
    • Comparison of in vitro activities of several new quinolones against respiratory pathogens and their abilities to select fluoroquinolone resistance
    • BOSWELL FJ, ANDREWS JM, JEVONS G, WISE R: Comparison of in vitro activities of several new quinolones against respiratory pathogens and their abilities to select fluoroquinolone resistance. J. Antimicrob. Chemother. (2002) 50:495-502.
    • (2002) J. Antimicrob. Chemother. , vol.50 , pp. 495-502
    • Boswell, F.J.1    Andrews, J.M.2    Jevons, G.3    Wise, R.4
  • 68
    • 0032515790 scopus 로고    scopus 로고
    • Quinolone resistance from a transferable plasmid
    • MARTÌNEZ-MARTÌNEZ L, PASCUAL A, JACOBY GA. Quinolone resistance from a transferable plasmid. Lancet (1998) 351:797-799.
    • (1998) Lancet , vol.351 , pp. 797-799
    • Martìnez-Martìnez, L.1    Pascual, A.2    Jacoby, G.A.3
  • 69
    • 0002380615 scopus 로고    scopus 로고
    • A strategy for fighting antibiotic resistance
    • DRILICA K: A strategy for fighting antibiotic resistance. ASM News (2001) 67:27-33.
    • (2001) ASM News , vol.67 , pp. 27-33
    • Drilica, K.1
  • 70
    • 0031927418 scopus 로고    scopus 로고
    • Prevalence of a putative efflux mechanism among fluoroquinolone-clinical isolates of Streptococcus pneumoniae
    • BRENWALD NP, GILL MJ, WISE R: Prevalence of a putative efflux mechanism among fluoroquinolone-clinical isolates of Streptococcus pneumoniae. Antimicrob. Agents Chemother. (1998) 42:2032-2035.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 2032-2035
    • Brenwald, N.P.1    Gill, M.J.2    Wise, R.3
  • 71
    • 0035929701 scopus 로고    scopus 로고
    • Resistance of Streptococcus pneumoniae to fluoroquinolones - United States, 1995-1999
    • Resistance of Streptococcus pneumoniae to fluoroquinolones - United States, 1995-1999. MMWR (2001) 50(37):800-804.
    • (2001) MMWR , vol.50 , Issue.37 , pp. 800-804
  • 72
    • 0037035122 scopus 로고    scopus 로고
    • Brief report: Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia
    • DAVIDSON R, CAVALCANTI R, BRUNTON JL et al.: Brief report: resistance to levofloxacin and failure of treatment of pneumococcal pneumonia. N. Engl. J. Med. (2002) 346:747-750.
    • (2002) N. Engl. J. Med. , vol.346 , pp. 747-750
    • Davidson, R.1    Cavalcanti, R.2    Brunton, J.L.3
  • 73
    • 0035882293 scopus 로고    scopus 로고
    • A nosocomial outbreak of fluoroquinolone-resistant Streptococcus pneumoniae
    • WEISS K, RESTIERI C, GAUTHIER R et al.: A nosocomial outbreak of fluoroquinolone-resistant Streptococcus pneumoniae. Clin. Infect. Dis. (2001) 33:517-522.
    • (2001) Clin. Infect. Dis. , vol.33 , pp. 517-522
    • Weiss, K.1    Restieri, C.2    Gauthier, R.3
  • 74
    • 0035282390 scopus 로고    scopus 로고
    • Risk factors for acquisition of levofloxacin-resistant Streptococcus pneumoniae: A case control study
    • HO PL, TSE WS, TSANG KWT et al.: Risk factors for acquisition of levofloxacin-resistant Streptococcus pneumoniae: a case control study. Clin. Infect. Dis. (2001) 33:701-707.
    • (2001) Clin. Infect. Dis. , vol.33 , pp. 701-707
    • Ho, P.L.1    Tse, W.S.2    Tsang, K.W.T.3
  • 75
    • 0035884479 scopus 로고    scopus 로고
    • Fluoroquinolone-resistant Streptococcus pneumoniae associated with levofloxacin therapy
    • URBAN C, RAHMAN N, ZHAO X, MARIANO S et al.: Fluoroquinolone-resistant Streptococcus pneumoniae associated with levofloxacin therapy. J. Infect. Dis. (2001) 184:794-798.
    • (2001) J. Infect. Dis. , vol.184 , pp. 794-798
    • Urban, C.1    Rahman, N.2    Zhao, X.3    Mariano, S.4
  • 76
    • 0034095261 scopus 로고    scopus 로고
    • New uses for new and old quinolones and the challenge of resistance
    • HOOPER DC: New uses for new and old quinolones and the challenge of resistance. Clin. Infect. Dis. (2000) 30:243-254.
    • (2000) Clin. Infect. Dis. , vol.30 , pp. 243-254
    • Hooper, D.C.1
  • 77
    • 0037101975 scopus 로고    scopus 로고
    • Severe and persistent hypoglycemia due to gatifloxacin interaction with oral hypoglycemic agents
    • MENZIES DJ, DORSAINVIL PA, CUNHA BA et al.: Severe and persistent hypoglycemia due to gatifloxacin interaction with oral hypoglycemic agents. Am. J. Med. (2002) 113:232-234.
    • (2002) Am. J. Med. , vol.113 , pp. 232-234
    • Menzies, D.J.1    Dorsainvil, P.A.2    Cunha, B.A.3
  • 78
    • 0032707693 scopus 로고    scopus 로고
    • Toxicity of quinolones
    • STHALMANN R, LODE H: Toxicity of quinolones. Drugs (1999) 58(Suppl. 2):37-42.
    • (1999) Drugs , vol.58 , Issue.SUPPL. 2 , pp. 37-42
    • Sthalmann, R.1    Lode, H.2
  • 80
    • 0035154266 scopus 로고    scopus 로고
    • Clinical utility of the new fluoroquinolones for treating respiratory and urinary tract infections
    • BLONDEAU JM: Clinical utility of the new fluoroquinolones for treating respiratory and urinary tract infections. Expert Opin. Investig. Drugs (2001) 10:213-237.
    • (2001) Expert Opin. Investig. Drugs , vol.10 , pp. 213-237
    • Blondeau, J.M.1
  • 81
    • 0032711437 scopus 로고    scopus 로고
    • Comparative tolerability of the newer fluoroquinolone antibacterials
    • BALL P, MANDELL L, NIKI Y, TILLOTSON G: Comparative tolerability of the newer fluoroquinolone antibacterials. Drug Safety (1999) 21:407-421.
    • (1999) Drug Safety , vol.21 , pp. 407-421
    • Ball, P.1    Mandell, L.2    Niki, Y.3    Tillotson, G.4
  • 82
    • 0037370249 scopus 로고    scopus 로고
    • Oral gemifloxacin once daily for five days compared with sequential therapy with IV ceftriaxone/oral cefuroxime (max of 10 days) in the treatment of hospitalised patients with acute exacerbations of chronic bronchitis
    • WILSON R, LANGAN C, BALL P, BATEMAN K, PYPSTRA R: Oral gemifloxacin once daily for five days compared with sequential therapy with IV ceftriaxone/oral cefuroxime (max of 10 days) in the treatment of hospitalised patients with acute exacerbations of chronic bronchitis. Respir. Med. (2003) 97:242-249.
    • (2003) Respir. Med. , vol.97 , pp. 242-249
    • Wilson, R.1    Langan, C.2    Ball, P.3    Bateman, K.4    Pypstra, R.5
  • 83
    • 0036861678 scopus 로고    scopus 로고
    • Oral gemifloxacin versus sequential therapy with intravenous ceftriaxone/oral cefuroxime with or without a macrolide in the treatment of patients hospitalised with community-acquired pneumonia: Randomized, open label, multicenter study of clinical efficacy and tolerability
    • LODE H, FILE TM, MANDELL LA, BALL P, PYPSTRA R, THOMAS M: Oral gemifloxacin versus sequential therapy with intravenous ceftriaxone/oral cefuroxime with or without a macrolide in the treatment of patients hospitalised with community-acquired pneumonia: randomized, open label, multicenter study of clinical efficacy and tolerability. Clin. Ther. (2002) 24:1915-1936.
    • (2002) Clin. Ther. , vol.24 , pp. 1915-1936
    • Lode, H.1    File, T.M.2    Mandell, L.A.3    Ball, P.4    Pypstra, R.5    Thomas, M.6


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