Manganese neurotoxicity and glutamate-GABA interaction

Neurochemistry International

Volumn 43, Issue 4-5, 2003, Pages 475-480

  Erikson, Keith M ^a   Aschner, Michael ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Glutamate GABA; Manganese; Neurotoxicity

Indexed keywords

4 AMINOBUTYRIC ACID; ASPARTIC ACID; DOPAMINE; GLUTAMIC ACID; MANGANESE; NEUROTRANSMITTER;

ANIMAL CELL; ASTROCYTE; CELL CULTURE; CONFERENCE PAPER; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; LABORATORY; METABOLISM; MOLECULAR BIOLOGY; MOLECULAR INTERACTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0038741908     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(03)00037-8     Document Type: Conference Paper

References (52)

1. ACC/SCN, 1992. Second report on the world nutrition situation, vol. 1. Global and regional results. ACC/SCN, Geneva.
2. Allen J.A., Mutkus L., Aschner M. Brain Res. 902:2001;92-100.
3. Aschner M., Gannon M., Kimmelberg H.K. Manganese (Mn) uptake and efflux in cultured rat astrocytes. J. Neurochem. 58:1992;730-735.
4. Berl S., Lajtha A., Waelsch A. Amino acid and protein metabolism. VI. Cerebral compartments of glutamic acid metabolism. J. Neurochem. 7:1961;186-197.
5. Brouillet E.P., Shinobu L., McGarvey U., Hochberg F., Beal M.F. Manganese injection into the rat striatum produces excitotoxic lesions by impairing energy metabolism. Exp. Neurol. 120:1993;89-94.
6. Calne D.B., Chu N.S., Huang C.C., Lu C.S., Olanow W. Manganism and idiopathic parkinsonism: similarities and differences. Neurology. 44:1994;1583-1586.
7. Carlsson M., Carlsson A. Interactions between glutamatergic and monoaminergic system within the basal ganglia - implications for schizophrenia and Parkinson's disease. Trends Neurosci. 13:1990;272-276.
8. Castro S.L., Zigmond M.J. Stress-induced increase in extracellular dopamine in striatum glutamatergic action via N-methyl-D-aspartate receptors in substantia nigra. Brain Res. 901:2001;47-54.
9. Chen Q., Connor J.R., Beard J.L. Brain iron, transferrin and ferritin concentrations are altered in developing iron-deficient rats. J. Nutr. 125:1995;1529-1535.
10. Chua A.C.G., Morgan E.H. Effects of iron deficiency and iron overload on manganese uptake and deposition in the brain and other organs of the rat. Biol. Trace Met. Res. 55:1996;39-54.
11. Critchfield J.W., Carl G.F., Keen C.L. The influence of manganese supplementation on seizure onset and severity, and brain monoamines in the genetically epilepsy prone rat. Epilepsy Res. 14:1993;3-10.
12. Cotman, C.W., Foster, A.C., Lanhorn, T., 1981. An overview of glutamate as a neurotransmitter. Adv. Biochem. Psychopharmacol., 271.
13. Crowe A., Morgan E.H. Iron and transferrin uptake in brain and cerebrospinal fluid in the rat. Brain Res. 592:1992;8-16.
14. Danbolt N.C. Glutamate uptake. Prog. Neurobiol. 65:2001;1-105.
15. Davis C., Wolf T., Greger J. Varying levels of manganese and iron affect absorption and gut endogenous losses of manganese by rats. J. Nutr. 122:1992;1300-1308.
16. Davis K.E., Straff D.J., Weinstein E.A., Bannerman P.G., Correale D.M., Rothstein J.D., Robinson M.B. Multiple signaling pathways regulate cell surface expression and activity of the excitatory amino acid carrier 1 subtype of Glu transporter in c6 glioma. J. Neurosci. 18:1998;2475-2485.
17. Dorman D.C., Struve M.F., James R.A., Marshall M.W., Parkinson C.U., Wong B.A. Influence of particle solubility on the delivery of inhaled manganese to the rat brain: manganese sulfate and manganese tetroxide pharmacokinetics following repeated (14-day) exposure. Toxicol. Appl. Pharmacol. 170:2001;79-87.
18. Erikson K.M., Aschner M. Manganese causes differential regulation of glutamate transporter (GLAST), taurine transporter, and metallothionein in cultured rat astrocytes. Neurotoxicology. 23:2002;595-602.
19. Erikson K.M., Pinero D.J., Connor J.R., Beard J.L. Regional brain iron, ferritin, and transferrin concentrations during iron deficiency and iron repletion in developing rats. J. Nutr. 127:1997;2030-2038.
20. Erikson K.M., Jones B.C., Beard J.L. Iron deficiency alters dopamine transporter functioning in rat striatum. J. Nutr. 130:2000;2831-2837.
21. Erikson K.M., Jones B.C., Hess E.J., Zhang Q., Beard J.L. Iron deficiency decreases dopamine D1 and D2 receptors in rat brain. Pharmacol. Biochem. Behav. 69:2001;409-418.
22. Erikson K.M., Shihabi Z.K., Aschner J.L., Aschner M. Manganese accumulates in iron-deficient rat brain regions in a heterogeneous fashion and is associated with neurochemical alterations. Biol. Trace Elem. Res. 87:2002;143-156.
23. Finley J.W. Manganese absorption and retention by young women is associated with serum ferritin concentration. Am. J. Clin. Nutr. 70:1999;37-43.
24. Graybiel A. Neurotransmitters and neuromodulators in the basal ganglia. Trends Neurosci. 13:1990;244-254.
25. Gwiazda R.H., Lee D., Sheridan J., Smith D.R. Sub-chronic low cumulative exposure to manganese affects striatal GABA but not dopamine. Neurotoxicology. 23:2002;69-76.
26. Hazell A.S., Norenberg M.D. Manganese decreases glutamate uptake in cultured astrocytes. Neurochem. Res. 22:1997;1443-1447.
27. Hertz L. Functional interaction between neurons and astrocytes. I. Turnover and metabolism of putative amino acid transmitters. Prog. Neurobiol. 13:1979;277-323.
28. Herynek V., Babis M., Trucecka P., Filip K., Vymazal J., Dezortova M., Hajek M. Chronic liver disease: relaxometry in the brain after liver transplantation. Magma. 12:2001;10-15.
29. Hurley, L.S., Keen, C.L., 1987. Manganese. In: Underwood, E., Mertz, W. (Eds.), Trace Elements in Human Health and Animal Nutrition. Academic Press, New York, pp. 185-223.
30. Ikeda S., Sera Y., Yoshida M., Ohshiro H., Uchino S., Oka Y., Lee K.J., Kotera A. Manganese deposits in patients with biliary atresia after hepatic porto-enterostomy. J. Pediat. Surg. 35:2000a;450-453.
31. Ikeda S., Yamaguchi Y., Sera Y., Ohshiro H., Uchino S., Yamashita Y., Ogawa M. Manganese deposition in the globus pallidus in patients with biliary atresia. Transplantation. 69:2000b;2339-2343.
32. Kondo K., Hashimoto H., Kitanaka J., Sawada M., Suzumura A., Marunouchi T., Baba A. Expression of glutamate transporters in cultured glial cells. Neursci. Lett. 188:1995;140-142.
33. Kwik-Uribe C.L., Golub M.S., Keen C.L. Chronic marginal iron intakes during early development in mice alter brain iron concentrations and behavior despite postnatal iron supplementation. J. Nutr. 130:2000;2040-2048.
34. Lafon-Cazal M., Culcasi M., Gaven F., Pietri S., Bockaert J. Nitric oxide, superoxide, and peroxynitrite: putative mediators of NMDA-induced cell death in cerebellar granule cells. Neuropharmacology. 32:1993;1259-1266.
35. Lai J.C.K., Leung T.K., Lim L. Differences in neurotoxic effects of manganese during development and aging: some observations on brain regional neurotransmitter and non-neurotransmitter metabolism in a developmental rat model of chronic manganese encephalopathy. Neurotoxicology. 5:1984;37-45.
36. Lipe G.W., Duhart H., Newhart G.D., Slikker W. Jr., Ali S.F. Effect of manganese on the concentration of amino acids in different regions of the rat brain. J. Environ. Sci. Health B. 34:1999;119-132.
37. Malecki E.A., Devenyi A.G., Barron T.F., Mosher T.J., Eslinger P., Flaherty-Craig C.V., Rossaro L. Iron and manganese homeostasis in chronic liver disease: relationship to pallidal T1-weighted magnetic resonance signal hyperintensity. Neurotoxicology. 20:1999a;647-652.
38. Malecki E.A., Devenyi A.G., Beard J.L., Connor J.R. Existing and emerging mechanisms for transport of iron and manganese to the brain. J. Neurosci. Res. 56:1999b;113-122.
39. Martinez-Hernandez A., Bell K.P., Norenberg M.D. Glutamine synthetase: glial localization in brain. Science. 195:1977;1356-1358.
40. Montes S., Alcaraz-Zubeldia M., Muriel P., Rios C. Striatal manganese accumulation induces changes in dopamine metabolism in the cirrhotic rat. Brain Res. 891:2001;123-129.
41. Olsen, R.W., DeLorey, T.M., 1999. GABA and glycine. In: Siegel, G.J., Agranoff, B.W., Albers, R.W., Fisher, S.K., Uhler, M.D. (Eds.), Basic Neurochemistry. Lipincott Williams and Wilkins, Philadelphia, pp. 335-346.
42. Page G., Peeters M., Najimi M., Maloteaux J.M., Hermans E. Modulation of the neuronal dopamine transporter activity by metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes. J. Neurochem. 76:2001;1282-1290.
43. Pal P.K., Samii A., Calne D.B. Manganese neurotoxicity: a review of clinical features, imaging and pathology. Neurotoxicology. 20:1999;227-238.
44. Pinero D.J., Li N.Q., Connor J.R., Beard J.L. Variations in dietary iron alter brain iron metabolism in developing rats. J. Nutr. 130:2000;254-263.
45. Rose C., Butterworth R.F., Zayed J., Normandin L., Todd K., Michalak A., Spahr L., Huet P.M., Pomier-Layrargues G. Manganese deposition in basal ganglia structures results from both portal-systemic shunting and liver dysfunction. Gastroenterology. 117:1999;640-644.
46. Reimund J.M., Dietemann J.L., Warter J.M., Baumann R., Duclos B. Factors associated to hypermanganesemia in patients receiving home parenteral nutrition. Clin. Nutr. 19:2000;343-348.
47. Trotti D., Danbolt N.C., Volterra A. Glutamate transporters are oxidant vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol. Sci. 19:1998;328-334.
48. Verity M.A. Manganese neurotoxicity: a mechanistic hypothesis. Neurotoxicology. 20:1999;489-498.
49. Waniewski R.A., Martin D.L. Exogenous glutamate is metabolized to glutamine and exported by primary astrocyte cultures. J. Neurochem. 47:1986;304-313.
50. Wedler F.C., Ley B.W., Grippo A.A. Manganese(II) dynamics and distribution in glial cells cultured from chick cerebral cortex. Biochem. Res. 14:1989;1129-1135.
51. Zheng W., Zhao Q., Slavkovich V., Aschner M., Graziano J.H. Alteration of iron homeostasis following chronic exposure to manganese in rats. Brain Res. 833:1999;125-132.
52. Zhou B.G., Norenberg M.D. Ammonia downregulates GLAST mRNA glutamate transporter in rat astrocyte cultures. Neurosci. Lett. 276:1999;145-148.