Forebrain Fos responses to reproductively related chemosensory cues in aromatase knockout mice

Brain Research Bulletin

Volumn 60, Issue 3, 2003, Pages 191-200

  Aste, N ^a   Honda, S ^a   Harada, N ^a  

^a FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Bed nucleus of the stria terminalis; Medial amygdala; Medial preoptic area; Pheromone; Sex differentiation; Vomeronasal system

Indexed keywords

AROMATASE; ESTROGEN; PHEROMONE; PROTEIN FOS;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; FOREBRAIN; GENOTYPE; HORMONE ACTION; IMMUNOREACTIVITY; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; OLFACTORY DISCRIMINATION; PREOPTIC AREA; PRIORITY JOURNAL; SEX DIFFERENTIATION; URINE; VOMERONASAL ORGAN; WILD TYPE;

EID: 0038738174     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(03)00035-2     Document Type: Article

References (41)

1. Bakker J., Baum M.J., Slob A.K. Neonatal inhibition of brain estrogen synthesis alters adult neural Fos responses to mating and pheromonal stimulation in the male rat. Neuroscience. 74:1996;251-260.
2. Bakker J., Brand T., van Ophemert J., Slob A.K. Hormonal regulation of adult partner preference behavior in neonatally ATD-treated male rats. Behav. Neurosci. 107:1993;480-487.
3. J. Bakker, S. Honda, N. Harada, Sexual partner preference requires a functional aromatase (Cyp 19) gene in male mice, Horm. Behav. 42 (2002) 158-171.
4. Bakker J., Van Ophemert J., Slob A.K. Sexual differentiation of odor and partner preference in the rat. Physiol. Behav. 60:1996;489-494.
5. Baum M.J., Everitt B.J. Increased expression of c-fos in the medial preoptic area after mating in male rats: role of afferent inputs from the medial amygdala and midbrain central tegmental field. Neuroscience. 250:1992;627-646.
6. Beyer C. Estrogen and the developing mammalian brain. Anat. Embryol. (Berl.). 199:1999;379-390.
7. Brennan P.A. The vomeronasal system. Cell. Mol. Life Sci. 58:2001;546-555.
8. Bressler S.C., Baum M.J. Sex comparison of neuronal fos immunoreactivity in the rat vomeronasal projection circuit after chemosensory stimulation. Neuroscience. 71:1996;1063-1072.
9. Canteras N.S., Simerly R.B., Swanson L.W. Connections of the posterior nucleus of the amygdala. J. Comp. Neurol. 324:1992;143-179.
10. Canteras N.S., Simerly R.B., Swanson L.W. Organization of projections from the medial nucleus of the amygdala: A PHAL study in the rat. J. Comp. Neurol. 360:1995;213-245.
11. Compaan J.C., Wozniak A., De Ruiter A.J.H., Koolhaas J.M., Hutchison J.B. Aromatase activity in the preoptic area differs between aggressive and nonaggressive male house mice. Brain Res. Bull. 35:1994;1-7.
12. Coolen L.M., Peters H.J., Veening J.G. Fos immunoreactivity in the rat brain following consummatory elements of sexual behavior: a sex comparison. Brain Res. 738:1996;67-82.
13. Coolen L.M., Peters H.J.P.W., Veening J.G. Distribution of Fos immunoreactivity following mating versus anogenital investigation in the male rat brain. Neuroscience. 77:1997;1151-1161.
14. Dominguez-Salazar E., Portillo W., Baum M.J., Bakker J., Paredes R.G. Effect of prenatal androgen receptor antagonist or aromatase inhibitor on sexual behavior, partner preference and neuronal Fos responses to estrous female odors in the rat accessory olfactory system. Physiol. Behav. 75:2002;337-346.
15. Fernandez-Fewell G.D., Meredith M. c-fos expression in vomeronasal pathways of mated or pheromone-stimulated male golden hamsters: contributions from vomeronasal sensory input and expression related to mating performance. J. Neurosci. 14:1994;3643-3654.
16. Fiber J.M., Swann J.M. Testosterone differentially influences sex-specific pheromone-stimulated Fos expression in limbic regions of Syrian hamsters. Horm. Behav. 30:1996;455-473.
17. Fisher C.R., Graves K.H., Parlow A.F., Simpson E.R. Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene. Proc. Natl. Acad. Sci. USA. 95:1998;6965-6970.
18. Gerardin D.C., Pereira O.C. Reproductive changes in male rats treated perinatally with an aromatase inhibitor. Pharmacol. Biochem. Behav. 71:2002;301-305.
19. Halem H.A., Cherry J.A., Baum M.J. Vomeronasal neuroepithelium and forebrain Fos responses to male pheromones in male and female mice. J. Neurobiol. 39:1999;249-263.
20. Heeb M.M., Yahr P. c-Fos immunoreactivity in the sexually dimorphic area of the hypothalamus and related brain regions of male gerbils after exposure to sex-related stimuli or performance of specific sexual behaviors. Neuroscience. 72:1996;1049-1071.
21. Herdegen T., Leah J.D. Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res. Brain Res. Rev. 28:1998;370-490.
22. Honda S., Harada N., Ito S., Takagi Y., Maeda S. Disruption of sexual behavior in male aromatase-deficient mice lacking exons 1 and 2 of the cyp19 gene. Biochem. Biophys. Res. Commun. 252:1998;445-449.
23. Hutchison J.B., Wozniak A., Beyer C., Karolczak M., Hutchison R.E. Steroid metabolising enzymes in the determination of brain gender. J. Steroid. Biochem. Mol. Biol. 69:1999;85-96.
24. Kollack S.S., Newman S.W. Mating behavior induces selective expression of Fos protein within the chemosensory pathways of the male Syrian hamster brain. Neurosci. Lett. 143:1992;223-228.
25. Kollack W.S., Newman S.W. Mating-induced expression of c-fos in the male Syrian hamster brain: role of experience, pheromones, and ejaculations. J. Neurobiol. 32:1997;481-501.
26. Kondo Y., Arai Y. Functional association between the medial amygdala and the medial preoptic area in regulation of mating behavior in the male rat. Physiol. Behav. 57:1995;69-73.
27. Lephart E.D. A review of brain aromatase cytochrome P450. Brain Res. Brain Res. Rev. 22:1996;1-26.
28. Liu Y.C., Salamone J.D., Sachs B.D. Lesions in medial preoptic area and bed nucleus of stria terminalis: differential effects on copulatory behavior and noncontact erection in male rats. J. Neurosci. 17:1997;5245-5253.
29. Mori K., von Campenhause H., Yoshihara Y. Zonal organization of the mammalian main and accessory olfactory systems. Philos. Trans. R Soc. Lond. B Biol. Sci. 355:2000;1801-1812.
30. Paredes R.G., Lopez M.E., Baum M.J. Testosterone augments neuronal Fos responses to estrous odors throughout the vomeronasal projection pathway of gonadectomized male and female rats. Horm. Behav. 33:1998;48-57.
31. Pfaus J.G., Heeb M.M. Implications of immediate-early gene induction in the brain following sexual stimulation of female and male rodents. Brain Res. Bull. 44:1997;397-407.
32. Robertson G.S., Pfaus J.G., Atkinson L.J., Matsumura H., Phillips A.G., Fibiger H.C. Sexual behavior increases c-fos expression in the forebrain of the male rat. Brain Res. 564:1991;352-357.
33. B.D. Sachs, R.L. Meisel, The physiology of male sexual behavior, in: E. Knobil, J.D. Neill (Eds.), The Physiology of Reproduction, vol. 2, Raven Press, New York, 1988, pp. 1393-1485.
34. Scalia F., Winans S.S. The differential projections of the olfactory bulb and accessory olfactory bulb in mammals. J. Comp. Neurol. 161:1975;31-55.
35. Simerly R.B., Swanson L.W. The organization of neural inputs to the medial preoptic nucleus of the rat. J. Comp. Neurol. 246:1986;312-342.
36. Strotmann J. Targeting of olfactory neurons. Cell. Mol. Life Sci. 58:2001;531-537.
37. Swann J., Rahaman F., Bijak T., Fiber J. The main olfactory system mediates pheromone-induced fos expression in the extended amygdala and preoptic area of the male Syrian hamster. Neuroscience. 105:2001;695-706.
38. Toda K., Okada T., Takeda K., Akira S., Saibara T., Shiraishi M., Onishi S., Shizuta Y. Oestrogen at the neonatal stage is critical for the reproductive ability of male mice as revealed by supplementation with 17β-estradiol to aromatase gene (Cyp 19) knockout mice. J. Endocrinol. 168:2001;455-463.
39. Toda K., Saibara T., Okada T., Onishi S., Shizuta Y. A loss of aggressive behaviour and its reinstatement by oestrogen in mice lacking the aromatase gene (Cyp19). J. Endocrinol. 168:2001;217-220.
40. Veening J.G., Coolen L.M. Neural activation following sexual behavior in the male and female rat brain. Behav. Brain Res. 92:1998;181-193.
41. Wersinger S.R., Rissman E.F. Oestrogen receptor alpha is essential for female-directed chemo-investigatory behaviour but is not required for the pheromone-induced luteinizing hormone surge in male mice. J. Neuroendocrinol. 12:2000;103-110.