C-Fos immunoreactivity in the sexually dimorphic area of the hypothalamus and related brain regions of male gerbils after exposure to sex-related stimuli or performance of specific sexual behaviors

Neuroscience

Volumn 72, Issue 4, 1996, Pages 1049-1071

  Heeb, M M ^a   Yahr, P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

ejaculation; medial amygdala; medial preoptic area; posterodorsal preoptic nucleus; subparafascicular thalamic nucleus

Indexed keywords

ONCOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EJACULATION; FEMALE; GERBIL; HYPOTHALAMUS; IMMUNOCYTOCHEMISTRY; MALE; MEDIAL PREOPTIC AREA; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; SEX DIFFERENCE; SEXUAL BEHAVIOR; THALAMUS NUCLEUS;

EID: 0029959976     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(95)00602-8     Document Type: Article

References (65)

1. Abraham W. C., Dragunow M. and Tate W. P. (1992) The role of immediate early genes in the stabilization of long-term potentiation. Molec. Neurobiol. 5, 297-314.
2. Baum M. J., Brown J. J. G., Kica E., Rubin B. S., Johnson R. S. and Papaioannou V. E. (1994) Effect of a null mutation of the c-fos proto-oncogene on sexual behavior of male mice. Biol. Reprod. 50, 1040-1048.
3. Baum M. J. and Everitt B. J. (1992) Increased expression of c-fos in the medial preoptic area after mating in male rats: role of afferent inputs from the medial amygdala and midbrain central tegmental field. Neuroscience 50, 627-646.
4. Beauchamp G. K., Yamazaki K., Curran M., Bard J. and Boyse E. A. (1994) Fetal H-2 odortypes are evident in the urine of pregnant female mice. Immunogenetics 39, 109-113.
5. Brackett N. L. and Edwards D. A. (1984) Medial preoptic connections with the midbrain tegmentum are essential for male sexual behavior. Physiol. Behav. 32, 79-84.
6. Brennan P. A., Hancock D. and Keverne E. B. (1992) The expression of the immediate-early genes c-fos, egr-1 and c-jun in the accessory olfactory bulb during the formation of an olfactory memory in mice. Neuroscience 49, 277-284.
7. Carr W. J., Loeb L. S. and Dissinger M. L. (1965) Responses of rats to sex odors. J. comp. physiol. Psychol. 59, 370-377.
8. Commins D. and Yahr P. (1984) Acetylcholinesterase activity in the sexually dimorphic area of the gerbil brain: sex differences and influences of adult gonadal steroids. J. comp. Neurol. 224, 123-131.
9. Commins D. and Yahr P. (1984) Adult testosterone levels influence the morphology of a sexually dimorphic area in the Mongolian gerbil brain. J. comp. Neurol. 224, 132-140.
10. Commins D. and Yahr P. (1985) Autoradiographic localization of estrogen and androgen receptors in the sexually dimorphic area and other regions of the gerbil brain. J. comp. Neurol. 231, 473-489.
11. Cotman C. W., Monaghan D. T. and Ganong A. H. (1988) Excitatory amino acid neurotransmission: NMDA receptors and Hebb-type synaptic plasticity. A. Rev. Neurosci. 11, 61-80.
12. Curran T. and Morgan J. I. (1994) Fos: an immediate-early transcription factor in neurons. J. Neurobiol. 26, 403-412.
13. De Vries G. J., Gonzales C. L. and Yahr P. (1988) Afferent connections of the sexually dimorphic area of the hypothalamus of male and female gerbils. J. comp. Neurol. 271, 91-105.
14. Dragunow M. and Faull R. (1989) The use of c-fos as a metabolic marker in neuronal pathway tracing. J. Neurosci. Meth. 29, 261-265.
15. Edwards D. A. and Isaacs S. (1991) Zona incerta lesions: effects on copulation, partner-preference and other socio-sexual behaviors. Behav. Brain Res. 44, 145-150.
16. Faull R. L. M. and Mehler W. R. (1985) Thalamus. In The Rat Nervous System, Vol. 1: Forebrain and Midbrain (ed. Paxinos G.), pp. 129-168. Academic Press, New York.
17. Fernandez-Fewell G. D. and Meredith M. (1994) C-fos expression in vomeronasal pathways of mated or pheromone-stimulated male Golden hamsters: contributions from vomeronasal sensory input and expression related to mating performance. J. Neurosci. 14, 3643-3654.
18. Fiber J. M., Adames P. and Swann J. M. (1993) Pheromones induce c-fos in limbic areas regulating male hamster mating behavior. Neuroreport 4, 871-874.
19. Finn P. D., De Vries G. J. and Yahr P. (1993) Efferent projections of the sexually dimorphic area of the gerbil hypothalamus: anterograde identification and retrograde verification in males and females. J. comp. Neurol. 338, 491-520.
20. Finn P. D. and Yahr P. (1993) Projection of the sexually dimorphic area of the gerbil hypothalamus to the retrorubral field is essential for male sexual behavior: role of A8 and other cells. Behav. Neurosci. 108, 362-378.
21. Hansen S. and Gummesson B. M. (1982) Participation of the lateral midbrain tegmentum in the neuroendocrine control of sexual behavior and lactation in the rat. Brain Res. 251, 319-325.
22. Hansen S. and Köhler C. (1984) The importance of the peripeduncular nucleus in the neuroendocrine control of sexual behavior and milk ejection in the rat. Neuroendocrinology 39, 563-572.
23. Heeb M. M. and Yahr P. (1993) C-fos in the sexually dimorphic area (SDA) of the gerbil hypothalamus, and related areas, during sexual activity. Soc. Neurosci. Abstr. 19, 1019.
24. Hoffman G. E., Smith M. S. and Verbalis J. G. (1993) C-Fos and related immediate early gene products as markers of activity in neuroendocrine systems. Front. Neuroendocr. 14, 173-213.
25. Hökfelt T., Mårtensson R., Björklund A., Kleinau S. and Goldstein M. (1984) Distributional maps of tyrosine-hydroxylase-immunoreactive neurons in the rat brain. In Handbook of Chemical Neuroanatomy, Vol. 2: Classical transmitters in the CNS, Part I (eds Björklund A. and Hökfelt T.), pp. 277-379. Elsevier Science, New York.
26. Holman S. D. and Hutchison J. B. (1991) Differential effects of neonatal castration on the development of sexually dimorphic brain areas in the gerbil. Devl Brain Res. 61, 147-150.
27. Holman S. D. and Hutchison J. B. (1991) Lateralized action of androgen on development of behavior and brain sex differences. Brain Res. Bull. 27, 261-265.
28. Kaczmarek L. (1992) Expression of c-fos and other genes encoding transcription factors in long-term potentiation. Behav. neural Biol. 57, 263-266.
29. Keppel G. (1982) Design and Analysis: A Researchers Handbook. Prentice-Hall, Englewood Cliffs, NJ.
30. Keverne E. B. and de la Riva C. (1982) Pheromones in mice: reciprocal interaction between the nose and brain. Nature 296, 148-150.
31. Keverne E. B., Levy F., Poindron P. and Lindsay D. R. (1983) Vaginal stimulation: an important determinant of maternal bonding in sheep. Science 219, 81-83.
32. Kollack S. S. and Newman S. W. (1992) Mating behavior induces selective expression of Fos protein within the chemosensory pathways of the male Syrian hamster brain. Neurosci. Lett. 143, 223-228.
33. Kollack-Walker S. and Newman S. W. (1995) Mating and agonistic behavior produce different patterns of Fos immunolabeling in the male Syrian hamster brain. Neuroscience 66, 721-736.
34. Maillard C.-A. and Edwards D. A. (1991) Excitotoxin lesions of the zona incerta/lateral tegmentum continuum: effects on male sexual behavior in rats. Behav. Brain Res. 46, 143-149.
35. Maillard-Gutekunst C.-A. and Edwards D. A. (1994) Preoptic and subthalamic connections with the caudal brainstem are important for copulation in the male rat. Behav. Neurosci. 108, 758-766.
36. Meredith M. (1986) Vomeronasal organ removal before sexual experience impairs male hamster mating behavior. Physiol. Behav. 36, 737-743.
37. Morgan J. I. and Curran T. (1989) Stimulus-transcription coupling in neurons: role of cellular immediate-early genes. Trends Neurosci. 12, 459-462.
38. Morgan J. I. and Curran T. (1991) Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. A. Rev. Neurosci. 14, 421-451.
39. Oboh A. M., Paredes R. G. and Baum M. J. (1995) A sex comparison of increments in FOS immunoreactivity in forebrain neurons of gonadectomized, testosterone-treated rats after mounting an estrous female. Ńeurobiol. Learning Memory 63, 66-73.
40. Page K. J. and Everitt B. J. (1993) Transsynaptic induction of c-fos in basal forebrain, diencephalic and midbrain neurons following AMPA-induced activation of the dorsal and ventral striatum. Expl Brain Res. 93, 399-411.
41. Palanza P. and Parmigiani S. (1991) Inhibition of infanticide in male Swiss mice: behavioral polymorphism in response to multiple mediating factors. Physiol. Behav. 49, 797-802.
42. Paxinos G. and Watson C. (1986) The Rat Brain in Stereotaxic Coordinates. Academic Press, New York.
43. Piechaszyk M. and Blanchard J.-M. (1994) C-fos proto-oncogene regulation and function. Crit. Rev. Oncol./Hemat. 17, 93-131.
44. Powers J. B., Newman S. W. and Bergondy M. L. (1987) MPOA and BNST lesions in male Syrian hamsters: differential effects on copulatory and chemoinvestigatory behaviors. Behav. Brain Res. 23, 181-195.
45. Powers J. B. and Winans S. S. (1975) Vomeronasal organ: critical role in mediating sexual behavior of the male hamster. Science 187, 961-963.
46. Robertson G. S., Pfaus J. G., Atkinson L. J., Matsumura H., Phillips A. G. and Fibiger H. C. (1991) Sexual behavior increases c-fos expression in the forebrain of the male rat. Brain Res. 564, 352-357.
47. Sagar S. M., Sharp F. R. and Curran T. (1988) Expression of c-fos protein in brain: metabolic mapping at the cellular level. Science 240, 1328-1331.
48. Sassone-Corsi P., Sisson J. C. and Verma I. M. (1988) Transcriptional autoregulation of the proto-oncogene fos. Nature 334, 314-319.
49. Sayag N., Hoffman N. W. and Yahr P. (1994) Telencephalic connections of the sexually dimorphic area of the gerbil hypothalamus that influence male sex behavior. Behav. Neurosci. 108, 743-757.
50. Schönthal A., Buscher M., Angel P., Rahmsdorf H. J., Ponta H., Hattori K., Chiu R., Karin M. and Herrlich P. (1989) The Fos and Jun/AP-1 proteins are involved in the downregulation of Fos transcription. Oncogene 4, 629-636.
51. Sheng M. and Greenberg M. E. (1990) The regulation and function of c-fos and other immediate early genes in the nervous system. Neuron 4, 477-485.
52. Shimura T. and Shimokochi M. (1991) Modification of male rat copulatory behavior by lateral midbrain stimulation. Physiol. Behav. 50, 989-994.
53. Simerly R. B., Chang C., Muramatsu M. and Swanson L. W. (1990) Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study. J. comp. Neurol. 294, 76-95.
54. Simerly R. B. and Swanson L. W. (1986) The organization of neural inputs to the medial preoptic nucleus of the rat. J. comp. Neural. 246, 312-342.
55. Simerly R. B. and Swanson L. W. (1988) Projections of the medial preoptic nucleus: a Phaseolus vulgaris leucoagglutinin anterograde tract-tracing study in the rat. J. comp. Neurol. 270, 209-242.
56. Simerly R. B., Swanson L. W. and Gorski R. A. (1984) Demonstration of a sexual dimorphism in the distribution of serotonin-immunoreactive fibers in the medial preoptic nucleus of the rat. J. comp. Neurol. 225, 151-166.
57. Swanson L. W. (1992) Brain Maps: Structure of the Rat Brain. Elsevier, Amsterdam.
58. Ulibarri C. M. and Yahr P. (1988) Role of neonatal androgens in sexual differentiation of brain structure, scent marking, and gonadotropin secretion in gerbils. Behav. neural Biol. 49, 27-44.
59. Ulibarri C. M. and Yahr P. (1993) Ontogeny of the sexually dimorphic area of the gerbil hypothalamus. Devl Brain Res. 74, 14-24.
60. Wersinger S. R., Baum M. J. and Erskine M. S. (1993) Mating-induced FOS-like immunoreactivity in the rat forebrain: a sex comparison and a dimorphic effect of pelvic nerve transection. J. Neuroendocr. 5, 557-568.
61. Winans S. S. and Powers J. B. (1977) Olfactory and vomeronasal deafferentation of male hamsters: histological and behavioral analyses. Brain Res. 126, 325-344.
62. Winer B. J. (1971) Statistical Principles in Experimental Design. McGraw-Hill, New York.
63. Witt D. M. and Insel T. R. (1994) Increased Fos expression in oxytocin neurons following masculine sexual behavior. J. Neuroendocr. 6, 13-18.
64. Wood R. I. and Newman S. W. (1993) Mating activates androgen receptor-containing neurons in chemosensory pathways of the male Syrian hamster brain. Brain Res. 614, 65-77.
65. Yahr P. and Gregory J. E. (1993) The medial and lateral cell groups of the sexually dimorphic area of the gerbil hypothalamus are essential for male sexual behavior and act via separate pathways. Brain Res. 631, 287-296.