Enrichment of trace chlorinated species in a complex matrix of fatty acids using HPLC in conjunction with gas chromatography-halogen specific detection

Journal of Liquid Chromatography and Related Technologies

Volumn 26, Issue 11, 2003, Pages 1809-1826

  Zhuang, Wenshan ^a,c   McKague, Bruce ^a   Carey, John ^a,b   Reeve, Douglas ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b ENVIRONMENT CANADA   (Canada)

^c Taro Pharmaceuticals Inc   (Canada)

Author keywords

Bleached kraft pulp mill effluent; Chlorinated fatty acids; Enrichment; Fish extracts; Halogen specific detection; HPLC; Lipids

Indexed keywords

FRACTIONATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION;

FLAME IONIZATION DETECTORS (FID);

FATTY ACIDS;

CHLORINE; FATTY ACID; HALOGEN; ORGANOCHLORINE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; CHLORINATION; CONTROLLED STUDY; FISH; FLAME PHOTOMETRY; FRACTIONATION; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PHYSICAL CHEMISTRY; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE;

ANIMALIA;

EID: 0038729456     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1081/JLC-120021287     Document Type: Article

References (12)

1. Newsome, W.H.; Andrews, P.; Conacher, H.B.S.; Rao, R.R.; Chatt, A. Total organochlorine content of fish from the Great Lakes. J. AOAC Int. 1993, 76 (4), 703-706.
2. Wesén, C.; Mu, H.; Kvernheim, A.L.; Larsson, P. Identification of chlorinated fatty acids in fish lipids by partitioning studies and by gas chromatography with Hall electrolytic conductivity detection. J. Chromatogr. A 1992, 625 (2), 257-269.
3. Åkesson Nilsson, G.; Nilsson, O.; Odenbrand, I.; Wesén, C. New halogen-specific detector applied to the analysis of chlorinated fatty acids. J. Chromatogr. A 2001, 912 (1), 99-106.
4. Wesén, C.; Mu, H.; Sundin, P.; Freyen, P.; Skramstad, J.; Odham, G. Gas chromatographic-mass spectrometric identification of chlorinated octadecanoic acids in eel lipids. J. Mass Spectrom. 1995, 30, 959-968.
5. Mu, H.; Wesén, C.; Novák, T.; Sundin, P.; Skramstad, J.; Odham, G. Enrichment of chlorinated fatty acids in fish lipids prior to analysis by capillary gas chromatography with electrolytic conductivity detection and mass spectrometry. J. Chromatogr. A 1996, 731, 225-236.
6. Milley, J.E.; Boyd, R.K.; Curtis, J.M.; Musial, C.; Uthe, J.F. Dichloromyristic acid, a major component of organochlorine load in lobster digestive gland. Environ. Sci. Technol. 1997, 31 (2), 535-541.
7. Zhuang, W.; Reeve, D.; Carey, J.; McKague, B. Effects of pulp mill effluents on occurrence of extractable organochlorine in fish. In 4th International Conference on Environmental Impacts of the Pulp and Paper Industry, Proceedings of the Conference, 12-15 June 2000, Helsinki, Finland Finnish Environment Institute: Helsinki, 2000; 317-323.
8. Zhuang, W. Extractable Organochlorine in Fish Downstream from Bleached Kraft Pulp Mills: Occurrence, Chemical Nature and Sources; University of Toronto, 2002; Ph.D. Thesis.
9. Munkittrick, K.R.; McMaster, M.E.; Van Der Kraak, G.; Portt, C.; Gibbons, W.N.; Farwell, A.; Gray, M. Development of Methods for Effects-Driven Cumulative Effects Assessment Using Fish Populations: Moose River Project; SETAC Press: Pensacola, FL, 2000.
10. Snyder, L.R.; Kirkland, J.J.; Glajch, J.L. Practical HPLC Method Development; 2nd Ed.; John Wiley & Sons: New York, 1997.
11. Zhuang, W.; McKague, B.; Carey, J.; Reeve, D. Identification of chlorinated fatty acids in fish using gas chromatography-mass spectrometry with negative chemical ionization of pentafluorobenzyl esters. J. Mass Spectrom., submitted for publication.
12. Zhuang, W.; McKague, B.; Reeve, D.; Carey, J. Identification and confirmation of traces of chlorinated fatty acids in fish downstream of bleached kraft pulp mills by gas chromatography with halogen specific detection. J. Chromatogr. A, in press.