Effect of the antitumor drug vinblastine on nuclear βII-tubulin in cultured rat kidney mesangial cells

Investigational New Drugs

Volumn 21, Issue 1, 2003, Pages 15-20

  Walss Bass, Consuelo ^a   Kreisberg, Jeffrey I ^a   Ludueña, Richard F ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

DNA fragmentation; Microtubules; Nuclear localization; Tubulin isotypes; Vinblastine

Indexed keywords

BETA 2 TUBULIN; BETA TUBULIN; DNA FRAGMENT; UNCLASSIFIED DRUG; VINBLASTINE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG TARGETING; MALE; MESANGIUM; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL NUCLEUS; CELLS, CULTURED; GLOMERULAR MESANGIUM; MALE; RATS; RATS, SPRAGUE-DAWLEY; TUBULIN; VINBLASTINE;

EID: 0038691838     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022947706151     Document Type: Article

References (25)

1. Dustin P (ed.): Microtubules, 2nd edn. Springer-Verlag, Berlin, 1984
2. Wilson L, Jordan MA: Pharmacological probes of microtubule function. In: Hyams JS, Lloyd CW (eds) Microtubules. Wiley-Liss, New York, 1994, pp 59-83
3. Gerzon K: Dimeric catharanthus alkaloids. In: Cassady JM, Douros JD (eds), Anticancer Agents Based on Natural Product Models. Academic Press, New York, 1980, pp 271-317
4. Owellen RJ, Hartke CA, Dickerson RM, Haines FO: Inhibition of tubulin microtubule polymerization by drugs of the Vinca alkaloid class. Cancer Res 36: 3798-3802, 1976
5. Na GC, Timasheff SN: In vitro vinblastine-induced tubulin paracrystals. J Biol Chem 257: 10387-10391, 1982
6. Jordan MA, Thrower D, Wilson L: Mechanism of inhibition of cell proliferation by Vinca alkaloids. Cancer Res 51: 2212-2222, 1991
7. II isotype of tubulin in the nuclei of cultured mesangial cells from rat kidney. Cell Motil Cytoskeleton 42: 274-284, 1999
8. II-tubulin in cultured cells. Cell Tiss Res 2002 (in press).
9. Tsukidate K, Yamamoto K, Snyder JW, Farber JL: Microtubule antagonists activate programmed cell death (apoptosis) in cultured rat hepatocytes. Am J Pathol 143: 918-925, 1993
10. Ausiello DA, Kreisberg JI, Roy C, Karnovsky MJ: Contraction of cultured cells of apparent mesangial origin after stimulation with angiotensin II and arginine vasopressin. J Clin Invest 65: 754-760, 1980
11. 2. Kidney Int 25: 874-879, 1984
12. Kreisberg JI, Venkatachalam MA: Vasoactive agents affect mesangial cell adhesion. Am J Physiol 251: C505-C511, 1986
13. Banerjee A, Roach MC, Wall KA, Lopata MA, Cleveland DW, Ludueña RF: A monoclonal antibody against the type II isotype of β-tubulin. Preparation of isotypically altered tubulin. J Biol Chem 263: 3029-3034, 1988
14. Roach MC, Boucher VL, Walss C, Ravdin P, Ludueña RF: Preparation of a monoclonal antibody specific for the class I isotype of β-tubulin: the β isotypes of tubulin differ in their cellular distributions within human tissues. Cell Motil Cytoskeleton 39: 273-285, 1998
15. Khan IA, Ludueña RF: Effect of vinblastine on the assembly of isotypically pure tubulins from bovine brain. Mol Biol Cell 6: 30a, 1995
16. II-tubulin in tumor cells: a possible novel target for taxol. Cell Motil Cytoskeleton, 2002 (in press)
17. Jordan MA, Wendell K, Gardiner D, Derry WB, Copp H, Wilson L: Mitotic block induced in HeLa cells by low concentrations of paclitaxel (taxol) results in abnormal mitotic exit and apoptotic cell death. Cancer Res 56: 816-825, 1996
18. Sorger PK, Dobles M, Tournebize R, Hyman AA: Coupling cell division and cell death to microtubule dynamics. Curr Opin Cell Biol 9: 807-814, 1997
19. II-tubulin in the nuclei of cultured rat kidney mesangial cells. Cell Motil Cytoskeleton 49: 208-217, 2001
20. Floege J, Topley N, Hoppe J, Barrett TB, Resch K: Mitogenic effect of platelet-derived growth factor in human glomerular mesangial cells: modulation and/or suppression by inflammatory cytokines. Clin Exp Immunol 86: 334-341, 1991
21. Creasey WA: Modifications in biochemical pathways produced by the Vinca alkaloids. Cancer Chemother Res 52: 501-507, 1968
22. Bernstam VA, Gray RH, Bernstein IA: Effect of microtubule-disrupting drugs on protein and RNA synthesis in Physarum polycephalum Amoebae. Arch Microbiol 128: 34-40, 1980
23. Jordan MA, Toso RJ, Thrower D, Wilson L: Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Proc Nat Acad Sci USA 90: 9552-9556, 1993
24. Derry WB, Wilson L, Jordan MA: Low potency of taxol at microtubule minus ends: implications for its antimitotic and therapeutic mechanism. Cancer Res 58: 1177-1184, 1998
25. Yvon AM, Wadsworth P, Jordan MA: Taxol suppresses dynamics of individual microtubules in living human tumor cells. Mol Biol Cell 10: 947-959, 1999