DING, a genistein target in human breast cancer: A protein without a gene

Journal of Nutrition

Volumn 133, Issue 7 SUPPL., 2003, Pages

  Belenky, Michael ^a   Prasain, Jeevan ^a,b   Kim, Helen ^a,b   Barnes, Stephen ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Affinity chromatography; Genistein; Peptide sequence

Indexed keywords

2 CARBOXYGENISTEIN; AGAROSE; ASPARTYLISOLEUCYLASPARAGINYLGLYCINAMIDE; DING PROTEIN; GENE PRODUCT; GENISTEIN; HIRUDIN; SEPHADEX; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; BINDING AFFINITY; BIOCHEMISTRY; BREAST CANCER; CELL FRACTIONATION; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOSOL; DRUG PROTEIN BINDING; DRUG TOLERANCE; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; PROTEIN ANALYSIS; PROTEIN TARGETING; REGULATORY MECHANISM;

MINK CELL FOCUS-FORMING VIRUS;

EID: 0038676412     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/133.7.2497s     Document Type: Conference Paper

References (44)

1. Dunn, J. E. (1975) Cancer epidemiology in populations of the United States - with emphasis on Hawaii and California - and Japan. Cancer Res. 35: 3240-3245.
2. Shimizu, H., Ross, R. K., Bernstein, L., Yatani, R., Henderson, B. E. & Mack, T. M. (1991) Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County, Br. J. Cancer 63: 963-966.
3. Tamimi, R. M., Lagiou, P., Adami, H. O. & Trichopoulos, D. (2002) Prospects for chemoprevention of cancer. J. Intern. Med. 251: 286-300.
4. Nagata, C., Kawakami, N. & Shimizu, H. (1997) Trends in the incidence rate and risk factors for breast cancer in Japan. Breast Cancer Res. Treat. 44: 75-82.
5. Messina, M. & Barnes, S. (1991) Workshop report from the Division of Cancer Etiology, National Cancer Institute, National Institutes of Health. The role of soy products in reducing risks of certain cancers. J. Natl. Cancer Inst. 83: 541-546.
6. Messina, M. J., Persky, V., Setchell, K. D. & Barnes, S. (1994) Soy intake and cancer risk: a review of the in vitro and in vivo data. Nutr. Cancer 21: 113-131.
7. Barnes, S. (1998) Phytoestrogens and breast cancer. Baillieres Clin. Endocrinol. Metab. 12: 559-579.
8. Coward, L., Barnes, N. C., Setchell, K. D. R. & Barnes, S. (1993) The antitumor isoflavones, genistein and daidzein, in soybean foods of American and Asian diets. J. Agric. Food Chem. 41: 1961-1967.
9. Bennetts, H. W., Underwood, E. J. & Shier, F. L. (1946) A specific breeding problem of sheep on subterranean clover pasture in western Australia. Aust. Vet. J. 22: 2-12.
10. Setchell, K. D., Gosselin, S. J., Welsh, M. B., Johnston, J. O., Balistreri, W. F., Kramer, L. W., Dresser, B. L. & Tarr, M. J. (1987) Dietary estrogens - a probable cause of infertility and liver disease in captive cheetahs. Gastroenterology 93: 225-233.
11. Santell, R. C., Chang, Y. C., Nair, M. G. & Helferich, W. G. (1997) Dietary genistein exerts estrogenic effects upon the uterus, mammary gland and the hypothalamic/pituitary axis in rats. J. Nutr. 127: 263-269.
12. Barnes, S., Grubbs, C., Setchell, K. D. R. & Carlson, J. (1990) Soybeans inhibit mammary tumors in models of breast cancer. Prog. Clin. Biol. Res. 347: 239-253.
13. Hawrylewicz, E. J., Zapata, J. J. & Blair, W. H. (1995) Soy and experimental cancer: animal studies. J. Nutr. 125 (suppl. 3): 698S-708S.
14. Lamartiniere, C. A., Moore, J. B., Brown, N. M., Thompson, R., Hardin, M. J. & Barnes, S. (1995) Genistein suppresses mammary cancer in rats. Carcinogenesis 16: 2833-2840.
15. Murrill, W. B., Brown, N. M., Zhang, J. X., Manzolillo, P. A., Barnes, S. & Lamartiniere, C. A. (1996) Prepubertal genistein exposure suppresses mammary cancer and enhances gland differentiation in rats. Carcinogenesis 17: 1451-1457.
16. Fritz, W. A., Coward, L., Wang, J. & Lamartiniere, C. A. (1998) Dietary genistein: pednatal mammary cancer prevention, bioavailability and toxicity testing in the rat. Carcinogenesis 19: 2151-2158.
17. Lamartiniere, C. A., Cotroneo, M. S., Fritz, W. A., Wang, J., Mentor-Marcel, R. & Elgavish, A. (2002) Genistein chemoprevention: timing and mechanisms of action in murine mammary and prostate. J. Nutr. 132: 552S-558S.
18. Shu, X. O., Jin, F., Dai, Q., Wen, W., Potter, J. D., Kushi, L. H., Ruan, Z., Gao, Y. T. & Zheng, W. (2001) Soyfood intake during adolescence and subsequent risk of breast cancer among Chinese women. Cancer Epidemiol. Biomarkers Prev. 10: 483-488.
19. Wu, H. W., Wan, P., Hankin, J., Tseng, C.-C., Yu, M. C. & Pike, M. C. (2002) Adolescent and adult soy intake and risk of breast cancer in Asian-Americans. Carcinogenesis 23: 1491-1496.
20. Hsieh, C. Y., Santell, R. C., Haslam, S. Z. & Helferich, W. G. (1998) Oestrogenic effects of genistein on the growth of oestrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo. Cancer Res. 58: 3833-3838.
21. Allred, C. D., Allred, K. F., Ju, Y. H., Virant, S. M. & Helferich, W. G. (2001) Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner. Cancer Res. 61: 5045-5050.
22. Allred, C. D., Ju, Y. H., Allred, K. F., Chang, J. & Helferich, W. G. (2001) Dietary genistin stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with genistein. Carcinogenesis 22: 1667-1673.
23. Barnes, S. & Peterson, T. G. (1995) Biochemical targets of the isoflavone genistein in tumor cell lines. Proc. Soc. Exp. Biol. Med. 208: 103-108.
24. Barnes, S., Boersma, B., Patel, R., Kirk, M., Darley-Usmar, V. M., Kim, H. & Xu, J. (2000) Isoflavonoids and chronic disease: mechanisms of action, Biofactors 12: 209-215.
25. Akiyama, T., Ishida, J., Nakagawa, S., Ogawara, H., Watanabe, S., Itoh, N., Shibuya, M. & Fukami, Y. (1987) Genistein, a specific inhibitor of tyrosine-specific protein kinases. J. Biol. Chem. 262: 5592-5595.
26. Adlercreutz, H., Markkanen, H. & Watanabe, S. (1993) Plasma concentrations of phyto-oestrogens in Japanese men, Lancet 342: 1209-1210.
27. Urban, D., Irwin, W., Kirk, M., Markiewicz, M. A., Myers, R., Smith, M., Weiss, H., Grizzle, W. E. & Barnes, S. (2001) The effect of isolated soy protein on plasma biomarkers in elderly men with elevated serum prostate specific antigen. J. Urol. 165: 294-300.
28. Kuiper, G. G., Carlsson, B., Grandien, K., Enmark, E., Haggblad, J., Nilsson, S. & Gustafsson, J. A. (1997) Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 138: 863-870.
29. Diel, P., Schulz, T., Smolnikar, K., Strunck, E., Vollmer, G. & Michna, H. (2000) Ability of xeno- and phyto-estrogens to modulate expression of estrogen-sensitive genes in rat uterus: estrogenicity profiles and uterotropic activity. J. Steroid. Biochem. Mol. Biol. 73: 1-10.
30. Naciff, J. M., Jump, M. L., Torontali, S. M., Carr, G. J., Tiesman, J. P., Overmann, G. J. & Daston, G. P. (2002) Gene expression profile induced by 17α-ethinyl estradiol, bisphenol A, and genistein in the developing female reproductive system of the rat. Toxicol. Sci. 68: 184-199.
31. Belenky, M. (1996) Isolation of a Genistein-Binding Protein from Human Breast Cancer MCF-7 Cells Using a Genistein-Agarose Affinity Column. Master's thesis, University of Alabama at Birmingham.
32. Berna, A., Bernier, F., Scott, K. & Stuhlmuller, B. (2002) Ring up the curtains on DING proteins. FEBS Lett. 524: 6-10.
33. Yoder, L., Cheng, E. & Burroughs, W. (1954) Synthesis of estrogenic isoflavone derivatives. Proc. Iowa Acad. Sci. 61: 271-275.
34. Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
35. Merril, C. R., Switzer, R. C. & Van Keuren, M. L. (1979) Trace polypeptides in cellular extracts and human body fluids detected by two-dimensional electrophoresis and a highly sensitive silver stain. Proc. Natl. Natl. Acad. Sci. U.S.A. 76: 4335-4339.
36. Towbin, H., Staehelin, T. & Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. U.S.A. 76: 4350-4354.
37. Chou, P. (1989) Prediction of protein structural classes from amino acid composition. In: Prediction of Protein Structure and the Principles of Protein Conformation (Fasman, G., ed.), pp. 549-586. Plenum Press, New York, NY.
38. Hain, N. A. K., Stuhlmuller, B., Hahn, G. R., Kalden, J. R., Deutzman, G. R. & Burmester, G. R. (1996) Biochemical characterization and microsequencing of a 205 kDa synovial protein stimulatory for T cells and reactive with rheumatoid factor containing sera. J. Immunol. 157: 1773-1780.
39. Adams, L., Davey, S. & Scott, K. (2002) The DING protein: an autocrine growth-stimulatory protein related to the human synovial stimulatory protein. Biochim. Biophys. Acta 1586: 254-264,
40. Riah, O., Dousset, J.-C., Bofill-Cardona, E. & Courriere, P. (2000) Isolation and microsequencing of a novel cotinine receptor. Cell. Mol. Neurobiol. 20: 653-664.
41. Ogawara, H., Akiyama, T., Watanabe, S., Ito, N., Kobori, M. & Seoda, Y. (1989) Inhibition of tyrosine protein kinase activity by synthetic isoflavones and flavones. J. Antibiot. 42: 340-343.
42. Peterson, G. (1995) Evaluation of the biochemical targets of genistein in tumor cells. J. Nutr. 125 (suppl. 3): 784S-789S.
43. Foo, L. Y., Lu, Y., Howell, A. B. & Vorsa, N. (2000) A-type proanthocyanidin trimers from cranberry that inhibit adherence of uropathogenic P-fimbriated Escherichia coli. J. Nat. Prod. 63: 1225-1228.
44. Li, Y., Hively, W. P. & Varmus, H. E. (2000) Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer. Oncogene 19: 1002-1009.