Sodium-hydrogen exchange inhibition preserves ventricular function after ventricular fibrillation in the intact swine heart

Journal of Thoracic and Cardiovascular Surgery

Volumn 125, Issue 6, 2003, Pages 1499-1509

  Rabkin, David G ^a   Cabreriza, Santos E ^a   LaCorte, Jared C ^a   Weinberg, Alan D ^a   Çoku, Lindita ^a   Walsh, Rowan ^a   Mosca, Ralph ^a   Spotnitz, Henry M ^a  

^a Columbia Coll of Phys/Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZAMIDE DERIVATIVE; BENZAMIDE N (AMINOIMINOMETHYL) 4 [4 (2 FURANYLCARBONYL) 1 PIPERAZINYL] 3 (METHYLSULFONYL)METHANESULFONATE; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA FLOW; ARTICLE; BLOOD PRESSURE; CONDUCTANCE; CONTROLLED STUDY; DEFIBRILLATOR; DIASTOLE; ECHOCARDIOGRAPHY; HEART LEFT VENTRICLE COMPLIANCE; HEART LEFT VENTRICLE MASS; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PRELOAD; HEART STROKE VOLUME; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE FUNCTION; HEART VENTRICLE PRESSURE; HEART WORK; IMPLANT; MALE; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; SWINE;

EID: 0038649610     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5223(02)73404-1     Document Type: Article

References (48)

1. Winkle RA, Mead RH, Ruder MA, et al. Ten year experience with implantable defibrillators. Circulation. 1991;84(Suppl):II-426.
2. Mirowski M. The automatic implantable cardioverter-defibrillator: an overview. J Am Coll Cardiol. 1985;6:461-6.
3. Spotnitz HM. Does ventricular fibrillation cause myocardial stunning during defibrillator implantation. J Card Surg. 1993;8(suppl):249-56.
4. Jeevanandam V, Bielefeld M, Auteri JS, et al. The implantable defibrillator: an electronic bridge to cardiac transplantation. Circulation. 1992;86(suppl II):II276-9.
5. Antunes ML, Spotnitz HM, Livelli FD, et al. Effects of electrophysiologic testing on ejection fraction during cardioverter/defibrillator implantation. Ann Thorac Surg. 1988;45:315-8.
6. Spotnitz HM, Hsu DT. Myocardial edema: importance in the study of left ventricular function. Adv Card Surg. 1994;5:1-25.
7. Spotnitz HM. Effects of ICD insertion. In: Spotnitz HM, editor. Research frontiers in implantable defibrillator surgery. Austin, Tex: RG Landes Co; 1992. p. 98-106.
8. Park WM, Amirhamzeh MMR, Jia CX, et al. Systolic arterial pressure recovery after ventricular fibrillation/flutter in humans. Pacing Clin Electrophysiol. 1994;17:1100-6.
9. Cole BN, Nicolosi AC, Uygur IJ, et al. Effects of simulated intraoperative electrophysiological testing on function of the canine left ventricle. Ann Thorac Surg. 1988;46:556-62.
10. Gazmuri R, Weil M, Bisera J, et al. Myocardial dysfunction after successful resuscitation from cardiac arrest. Crit Care Med. 1996;24:992-1000.
11. Karmazyn M. The sodium-hydrogen exchange system in the heart: its role in ischemic and reperfusion injury and therapeutic implications. Can J Cardiol. 1996;12:1074-82.
12. Bethencourt D, Laks H. Importance of edema and compliance changes during 24 hours of preservation of the dog heart. J Thorac Cardiovasc Surg. 1981;81:440-9.
13. Klein H, Pich S, Bohle R, Wollenweber J, Nebendahl K. Myocardial protection by Na-H exchange inhibition in ischemic reperfused porcine hearts. Circulation. 1995;92:912-7.
14. Miura T, Ogawa T, Suzuki K, Goto M, Shimamoto K. Infarct size limitation by a new Na-H exchange inhibitor HOE642: difference from preconditioning in the role of protein kinase C. J Am Coll Cardiol. 1997;29:693-701.
15. Symons JD. Na-H exchange inhibition with cariporide limits functional impairment caused by repetitive ischemia. J Cardiovasc Pharmacol. 1998;32:853-62.
16. Scholz W, Albus U, Counillon L, et al. Protective effects of HOE 642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion. Cardiovasc Res. 1995;29:260-8.
17. Shipolini AR, Galinanes M, Edmondson SJ, Hearse DJ, Avkiran M. Na/H exchange inhibitor HOE-642 imporves cardioplegic myocardial preservation under both normothermic and hypothermic conditions. Circulation. 1997;96(suppl 9):II-266-73.
18. Kevelaitis E, Oub E, Naissa A, Mouas C, Peynet J. Menasch P. Ischemic preconditioning with opening of mitochondrial adenosine triphosphate-sensitive potassium channels or Na/H exchange inhibition: which is the best protective strategy for heart transplants? J Thorac Cardiovasc Surg. 2001;121:155-62.
19. Moffat MP, Karmazyn M. Protective effects of the potent Na/H exchange inhibitor methylisobutyl amiloride against post-ischemic contractile dysfunction in rat and guinea-pig hearts. J Mol Cell Cardiol. 1993;25:959-71.
20. Martin J, Sarai K, Yoshitake M, et al. Orthotopic transplantation of pig hearts harvested after 30 min of normothermic ischemia: controlled reperfusion with blood cardioplegia containing the Na-H exchange inhibitor HOE 642. Eur J Cardiothorac Surg. 1998;14:607-14.
21. Kim YI, Herijgers P, Laycock SK, Van Lommel A, Verbeken E, Flameng WJ. Na/H exchange inhibition improves long-term myocardial preservation. Ann Thorac Surg. 1998;66:436-42.
22. Kim YI, Herijgers P, Van Lommel A, Verbeken E, Flameng W. Na/H exchange inhibition improves post-transplant myocardial compliance in 4-hour stored donor hearts. Cardiovasc Surg. 1998;6:67-75.
23. Rupprecht H-J, vom Dahl J, Terres W, et al. Cardioprotective effects of the Na/H exchange inhibitor cariporide in patients with acute anterior myocardial infarction undergoing direct PTCA. Circulation. 2000;101:2902-8.
24. Theroux P, Chaitman BR, Danchin N, et al. Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations. Circulation. 2000;102:3032-8.
25. White FC, Blolor CM. The pig as a model for myocardial ischemia. In: Tumbleson ME, editor. Swine in biomedical research. Vol. 1. New York: Plenium Press; 1986. p. 481-90.
26. Cabreriza SE, Dean DA, Jia CX, Dickstein ML, Spotnitz HM. Electrical isolation of the heart. Stabilized parallel conductance for left ventricular volume measurement. ASAIO J. 1997;43:M509-14.
27. Gumina RJ, Buerger E, Eickmeier C, Moore J, Daemmgen J, Gross GJ. Inhibition of the Na/H exchanger confers greater cardioprotection against 90 minutes of myocardial ischemia than ischemic preconditioning in dogs. Circulation. 1999;100:2519-26.
28. Powell WJ, Bianco J, Freedberg LE, Dinsmore RE, Sanders CA, Daggett WM. Artifactual changes in apparent left ventricular compliance due to atrial clamping. Appl Physiol. 1970;78:515-8.
29. Baan J, Van der Valde ET, DeBruin HG, et al. Continuous measurement of left ventricular volume in animal and humans by conductance catheter. Circulation. 1984;70:812-23.
30. Baan J, Steendijk P, Koops J. Calibration and application of the conductance catheter for ventricular volume measurement. Automedica. 1989;11:357-65.
31. Glower DD, Spratt JA, Snow ND, et al. Linearity of the Frank-Starling relationship in the intact heart: the concept of preload recruitable stroke work. Circulation. 1985;71:994-1009.
32. Sagawa K. The ventricular pressure-volume diagram revisited. Circ Res. 1978;43:677-86.
33. Amirhamzeh MMR, Jia C-X, Park WM, Dickstein ML, Spotnitz HM. Systolic arterial pressure recovery after ventricular fibrillation in pigs. Ann Thorac Surg. 1994;58:1374-9.
34. Soto PF, Jia C-X, Carter YM, et al. Effect of improved myocardial protection on edema and diastolic properties of the rat left ventricle during acute allograft rejection. J Heart Lung Transplant. 1998;17:608-16.
35. Littell RC, Milliken GA, Stroup WW, Wolfinger RD. SAS System for Mixed Models. Cary, NC: SAS Institute Inc; 1996.
36. Verbeke G, Molenberghs G. Linear mixed models for longitudinal data. New York: Springer-Verlag; 2000.
37. Xie J, Weil MH, Sun S, et al. High-energy defibrillation increases the severity of postresuscitation myocardial dysfunction. Circulation. 1997;96:683-8.
38. Doherty PW, McLaughlin PR, Billingham M, et al. Cardiac damage produced by direct current countershock applied to the heart. Am J Cardiol. 1979;43:225-32.
39. Kerber RE, Partins JB, Gascho JA, et al. Effect of direct-current counter-shocks on regional myocardial contractility and perfusion: experimental studies. Circulation. 1981;63:323-32.
40. Tang W, Weil MH, Sun S, et al. Myocardial dysfunction after successful resuscitation from cardiac arrest. Crit Care Med. 1993;21:1046-50.
41. Gazmuri RJ, Berkowitz M, Cajigas H. Myocardial effects of ventricular fibrillation in the isolated rat heart. Crit Care Med. 1999;27:154-250.
42. Kern KB. Myocardial dysfunction after resuscitation from cardiac arrest; an example of global myocardial stunning. J Am Coll Cardiol. 1996;28:232-40.
43. Deantonio HJ, Kaul S, Lerman BB. Reversible myocardial depression in survivors of cardiac arrest. Pacing Clin Electrophysiol. 1990;13:982-5.
44. 2+ responsiveness and altered diastolic function in intact ventricular muscle. Circ Res. 1995;76:1036-48.
45. Gazmuri RJ, Ayoub A, Hoffner E, Kolarova J. Successful ventricular defibrillation by the selective sodium-hydrogen exchange isoform-1 inhibitor cariporide. Circulation. 2001;104:234-9.
46. Kusuoka H, Porterfield JK, Wisman HF, et al. Pathophysiology and pathogenesis of stunned myocardium: Depressed Ca++ activation of contraction as a consequence of reperfusion-induced cellular calcium overload. J Clin Invest. 1987;79:950-61.
47. Krause SM, Jacobus WE, Becker LC. Alterations in cardiac sarcoplasmic reticulum calcium transport in the postischemic "stunned myocardium." Circ Res. 1989;65:526-30.
48. Hsu DT, Weng Z-C, Nicolosi AC, Detwiler PW, Sciacca R, Spotnitz HM. Quantitative effects of myocardial edema on the left ventricular pressure-volume relation. J Thorac Cardiovasc Surg. 1993;106:651-7.