Na+/H+ exchange inhibition improves posttransplant myocardial compliance in 4-hour stored donor hearts

Cardiovascular Surgery

Volumn 6, Issue 1, 1997, Pages 67-75

  Kim, Y I ^a   Herijgers, P ^a   Van Lommel, A ^a   Verbeken, E ^a   Flameng, W ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Brain death; Experimental heart transplantation; Heart preservation; Myocardial compliance; Na+ H+ exchange inhibitors

Indexed keywords

4 ISOPROPYL 3 METHYLSULFONYLBENZOYLGUANIDIN METHANESULFONATE; ANTIPORTER INHIBITOR; CARIPORIDE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; BRAIN DEATH; CARDIOPULMONARY BYPASS; HEART INDEX; HEART LEFT VENTRICLE COMPLIANCE; HEART MUSCLE BIOPSY; HEART PRESERVATION; HEART TRANSPLANTATION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL;

EID: 0344157337     PISSN: 09672109     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0967-2109(97)00080-X     Document Type: Article

References (38)

1. Hosenpud J. D., Novick R. J., Breen T. J., Daily O. P. The registry of the international society for heart and lung transplantation: eleventh official report. Journal of Heart and Lung Transplantation. 13:1994;561-570.
2. Emery R. W., Copeland J. G. Cardiac donor: a six-year experience. Annals of Thorac Surgery. 41:1986;356-362.
3. + exchange in cardiac physiology and pathophysiology; mediation of myocardial reperfusion injury by the pH paradox. Cardiovascular Research. 27:1993;915-924.
4. Lotan C. S., Miller S. K., Pohost G. M., Elgavish G. A. Amiloride in ouabain-induced acidification, inotropy and arrhythmia: 23Na and 31P NMR in perfused Hearts. Journal of Molecular and Cellular Cardiology. 24:1992;243-257.
5. Nishida M., Borzak S., Kraemer B.et al. Role of cation gradients in hypercontracture of myocytes during simulated ischemia and reperfusion. American Journal of Physiology. 264:1993;H1896-H1906.
6. + exchange in myocardium: effects of hypoxia and acidification on Na and Ca. American Journal of Physiology. 259:1990;C940-C948.
7. Cairns S. P., Alien D. G. Changes in myoplasmic pH and calcium concentration during exposure to lactate in isolated rat ventricular myocytes. Journal of Physiology. 464:1993;561-574.
8. Bethencourt D., Laks H. Importance of edema and compliance changes during 24 hours of preservation of the dog heart. Journal of Thoracic and Cardiovascular Surgery. 81:1981;440-449.
9. Yano K., Maruyama T., Makino N., Matsui H., Yanaga T. Effects of amiloride on the mechanical, electrical and biochemical aspects of ischemia-reperfusion injury. Molecular and Cellular Biochemistry. 121:1993;75-83.
10. + exchanger and reperfusion-induced ventricular arrhythmias in isolated perfused heart: possible role of amiloride. Molecular and Cellular Biochemistry. 119:1993;151-157.
11. + exchange and ischemic heart disease. American Journal of Cardiovascular Physiology. 4:1992;91-102.
12. + exchange prevents ventricular fibrillation and preserves function in porcine stunned myocardium. Journal of Molecular and Cellular Cardiology. 24(I):1992;S92.
13. Burt J. M., Copeland J. G. Myocardial function after preservation for 24 hours. Journal of Thoracic and Cardiovascular Surgery. 92:1986;238-246.
14. Cross C. E., Rieben P. A., Salisbury P. F. Influence of coronary perfusion and myocardial edema on pressure-volume diagram of left ventricle. American Journal of Physiology. 201:1961;102-108.
15. Hsu D. T., Weng Z.-C., Nicolosi A. C., Detwiler P. W., Sciacca R., Spotnitz H. M. Quantitative effects of myocardial edema on the left ventricular pressure-volume relation. Influence of cardioplegia osmolarity over two hours of ischemic arrest. Journal of Thoracic Cardiovascular Surgery. 106:1993;651-657.
16. Lazar H. L., Haasler G. B., Sponitz W. D.et al. Compliance, mass, and shape of the canine left ventricle after global ischemia analyzed with two-dimensional echocardiography. Journal of Surgical Research. 39:1985;199-208.
17. Amirhamzeh M. M.R., Jia C. X., Starr J. P.et al. Diastolic function in the heterotopic rat heart transplant model-effect of edema, ischemia, and rejection. Journal of Thoracic Cardiovascular Surgery. 108:1994;928-937.
18. Lee B. Y., Willson G. J., Domenech R. J., MacGregor D. C. Relative roles of edema versus contracture in the myocardial postischemic 'No-Reflow' phenomenon. Journal of Surgical Research. 29:1980;50-61.
19. Kloner R. A., Ganote C. E., Jennings R. B. The 'No-Reflow' phenomenon after temporary coronary occlusion in the dog. Journal of Clinical Investigation. 54:1974;1496-1508.
20. + exchange and its inhibition in cardiac ischemia and reperfusion. Basic Research in Cardiology. 88:1993;443-455.
21. + exchange inhibitors against cardiac injury produced by ischemia/reperfusion hypoxia/reoxygenation, and the calcium paradox. Journal of Cardiovascular Pharmacology. 21:1993;172-178.
22. + exchange inhibitors reverse lactate-induced depression in postischemic ventricular recovery. British Journal of Pharmacology. 108:1993;50-56.
23. + exchange system. Circulation Research. 74:1994;794-805.
24. Harada K., Johnson R. G., Grossman W., Morgan J. P. Acidemia and hypernatremia enhance postischemic recovery of excitation-contraction coupling. Circulation Research. 74:1994;1197-1209.
25. ++ overload in isolated perfused rabbit heart. Circulation. 89:1994;2787-2798.
26. + exchange inhibitor and its effects in cardiac ischemia. British Journal of Pharmacology. 109:1993;562-568.
27. + exchange inhibitors in cardiac ischemia. Journal of Molecular and Cellular Cardiology. 24:1992;731-740.
28. + exchange inhibitor HOE694. Annals of Thoracic Surgery. 61:1996;1400-1406.
29. Bittner H. B., Kendall S. W.H., Chen E. P., Davis R. D., Van Trigt P. III Myocardial performance after graft preservation and subsequent cardiac transplantation from brain-dead donors. Annals of Thoracic Surgery. 60:1995;47-54.
30. Shivalkar B., Van Loon J., Wieland W.et al. Variable effects of explosive or gradual increase of intracranial pressure on myocardial structure and function. Circulation. 87:1993;230-239.
31. Wexler L. F., Weinberg E. O., Ingwall J. S., Apstein C. S. Acute alterations in diastolic left ventricular chamber dispensability: mechanistic differences between hypoxemia and ischemia in isolated perfused rabbit and rat hearts. Circulation Research. 59:1986;515-528.
32. max for heart size. Heart Vessels. 2:1986;67-73.
33. Suga H. Ventricular energetics. Physiological Reviews. 70:1990;247-277.
34. Kass D. A., Beyer R., Lankford E., Heard M., Maughan W. L., Sagawa K. Influence of contractile state on curvilinearity of in situ end-systolic pressure-volume relations. Circulation. 79:1989;167-178.
35. Mulier, J. P., Ventricular pressure as a function of volume and flow-an analytical description of cardiac function. PhD Thesis, Catholic University of Leuven, Leuven, 1994, pp 45-56.
36. Goto Y., Slinker B. K., LeWinter M. M. Accuracy of volume measurement of rabbit left ventricle by balloon method. American Journal of Physiology. 255:1988;H394-H396.
37. Meyers C. H., D'Amico T. A., Peterseim D. S.et al. Effects of triiodothyronine and vasopressin on cardiac function and myocardial blood flow after brain death. Journal of Heart and Lung Transplantations. 12:1993;68-80.
38. Duan J., Karmazyn M. Protective effects of amiloride on the ischemic reperfused rat heart. Relation to mitochondrial function. European Journal of Pharmacology. 210:1992;149-157.