Positive inotropic effect of ceramide in adult ventricular myocytes: Mechanisms dissociated from its reduction in Ca2+ influx

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 285, Issue 2 54-2, 2003, Pages

  Liu, Shi J ^a,b   Kennedy, Richard H ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Calcium; Contractile function; Excitation contraction coupling; Heart; Lipid metabolites; Sphingolipid

Indexed keywords

CAFFEINE; CALCIUM CHANNEL L TYPE; CALCIUM ION; CERAMIDE; SPHINGOLIPID; SPHINGOMYELIN PHOSPHODIESTERASE;

ANIMAL CELL; ARTICLE; CALCIUM CHANNEL L TYPE CURRENT; CALCIUM CURRENT; CALCIUM TRANSPORT; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EXCITATION CONTRACTION COUPLING; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; HEART VENTRICLE; INOTROPISM; ISOLATED HEART; LUSITROPISM; MALE; MYOFILAMENT; NONHUMAN; PATCH CLAMP; POSTREST POTENTIATED CONTRACTION; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM; STEADY STATE CONTRACTION; VASOCONSTRICTION;

EID: 0038638290     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.01098.2002     Document Type: Article

References (38)

1. Andrieu-Abadie N, Jaffrezou JP, Hatem S, Laurent G, Levade T, and Mercadier JJ. L-Carnitine prevents doxorubicin-induced apoptosis of cardiac myocytes: role of inhibition of ceramide generation. FASEB J 13: 1501-1510, 1999.
2. Ballou LR, Chao CP, Holness MA, Barker SC, and Raghow R. Interleukin-1-mediated PGE2 production and sphingomyelin metabolism. Evidence for the regulation of cyclooxygenase gene expression by sphingosine and ceramide. J Biol Chem 267: 20044-20050, 1992.
3. Ballou LR, Laulederkind SJF, Rosloniec EF, and Raghow R. Ceramide signalling and the immune response. Biochim Biophys Acta 1301: 273-287, 1996.
4. Bankers-Fulbright JL, Kalli KR, and McKean DJ. Interleukin-1 signal transduction. Life Sci 59: 61-83, 1996.
5. Bassani JWM, Bassani RA, and Bers DM. Relaxation in rabbit and rat cardiac cells: species-dependent differences in cellular mechanisms. J Physiol 476: 279-293, 1994.
6. Bers DM. Calcium fluxes involved in control of cardiac myocyte contraction. Circ Res 87: 275-281, 2000.
7. Bers DM, Bassani RA, Bassani JWM, Baudet S, and Hryshko LV. Paradoxical twitch potentiation after rest in cardiac muscle: increased fractional release of SR calcium. J Mol Cell Cardiol 25: 1047-1057, 1993.
8. Bielawska AE, Shapiro JP, Li JA, Melkonyan HS, Piot C, Wolfe CL, Tomei LD, Hannun YA, and Umansky SR. Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion. Am J Pathol 151: 1257-1263, 1997.
9. Condrescu M and Reeves JP. Inhibition of sodium-calcium exchange by ceramide and sphingosine. J Biol Chem 276: 4046-4054, 2001.
10. Dettbarn CA, Betto R, Salviati G, Palade P, Jenkins GM, and Sabbadini RA. Modulation of cardiac sarcoplasmic reticulum ryanodine receptor by sphingosine. J Mol Cell Cardiol 26: 229-242, 1994.
11. Dinarello CA. The interleukin-1 family: 10 years of discovery. FASEB J 8: 1314-1325, 1994.
12. 2+] during inotropic interventions in isolated rat myocytes. J Physiol 437: 351-375, 1991.
13. Grunicke HH and Uberall F. Protein kinase C modulation. Semin Cancer Biol 3: 351-360, 1992.
14. Hamill OP, Neher E, Sakmann B, and Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 391: 85-100, 1981.
15. Hannun YA and Obeid LM. Ceramide: an intracellular signal for apoptosis. Trends Biochem Sci 20: 73-77, 1995.
16. Hannun YA, Obeid LM, and Wolff RA. The novel second messenger ceramide: identification, mechanism of action, and cellular activity. Adv Lipid Res 35: 43-64, 1993.
17. Hazen SL and Gross RW. Principles of membrane biochemistry and their application to the pathophysiology of cardiovascular disease. In: The Heart and Cardiovascular System, edited by Fozzard HA, Haber E, Jennings RB, Katz AM, and Morgan HE. New York: Raven, 1992, p. 839-860.
18. Hernandez OM, Discher DJ, Bishopric NH, and Webster KA. Rapid activation of neutral sphingomyelinase by hypoxiareoxygenation of cardiac myocytes. Circ Res 86: 198-204, 2000.
19. Jayadev S and Hannun YA. Ceramide: role in growth inhibitory cascades. J Lipid Mediat Cell Signal 14: 295-301, 1996.
20. Jayadev S, Linardic CM, and Hannun YA. Identification of arachidonic acid as a mediator of sphingomyelin hydrolysis in response to tumor necrosis factor alpha. J Biol Chem 269: 5757-5763, 1994.
21. Ji L, Zhang G, Uematsu S, Akahori Y, and Hirabayashi Y. Induction of apoptotic DNA fragmentation and cell death by natural ceramide. FEBS Lett 358: 211-214, 1995.
22. Kolesnick R and Golde DW. The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling. Cell 77: 325-328, 1994.
23. Krönke M, Schütze S, Wiegmann K, and Machleidt T. Sphingomyelinases and TNF-induced apoptosis. Cell Physiol Biochem 6: 337-344, 1996.
24. Krown KA, Page MT, Nguyen C, Zechner D, Gutierrez V, Comstock KL, Glembotski CC, Quintana PJE, and Sabbadini RA. Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes-involvement of the sphingolipid signaling cascade in cardiac cell death. J Clin Invest 98: 2854-2865, 1996.
25. 2+ current by interleukin-1β in cultured rat ventricular myocytes. Am J Physiol Cell Physiol 268: C339-C349, 1995.
26. 2+ cycling by lysoplasmenylcholine in adult rabbit ventricular myocytes. Am J Physiol Cell Physiol 284: C826-C838, 2003.
27. Mathias S and Kolesnick R. Ceramide: a novel second messenger. Adv Lipid Res 25: 65-90, 1993.
28. Mathias S, Younes A, Kan CC, Orlow I, Joseph C, and Kolesnick RN. Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1β. Science 259: 519-522, 1993.
29. 2+ channel conductance. Circ Res 75: 981-989, 1994.
30. Ogretmen B and Hannun YA. Updates on functions of ceramide in chemotherapy-induced cell death and in multidrug resistance. Drugs 4: 368-377, 2001.
31. 2+ current in adult rat ventricular myocytes. Am J Physiol Heart Circ Physiol 272: H2591-H2598, 1997.
32. Schutze S, Machleidt T, and Kronke M. The role of diacyl-glycerol and ceramide in tumor necrosis factor and interleukin-1 signal transduction. J Leukoc Biol 56: 533-541, 1994.
33. Spiegel S, Olivera A, and Carlson RO. The role of sphingosine in cell growth regulation and transmembrane signaling. Adv Lipid Res 25: 105-129, 1993.
34. Spurgeon HA, DuBell WH, Stern MD, Sollott SJ, Ziman BD, Silverman HS, Capogrossi MC, Talo A, and Lakatta EG. Cytosolic calcium and myofilaments in single rat cardiac myocytes achieve a dynamic equilibrium during twitch relaxation. J Physiol 447: 83-102, 1992.
35. Webster RJ, Sabbadini RA, Dettbarn CA, and Paolini PJ. Sphingosine effects on the contractile behavior of skinned cardiac myocytes. J Mol Cell Cardiol 26: 1273-1290, 1994.
36. Wier WG, Egan TM, Lopez-Lopez JR, and Balke CW. Local control of excitation-contraction coupling in rat heart cells. J Physiol 474: 463-471, 1994.
37. Yang Z, Costanzo M, Golde DW, and Kolesnick RN. Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor kappa B translocation in intact HL-60 cells. J Biol Chem 268: 20520-20523, 1993.
38. Yasui KJ and Palade P. Sphingolipid actions on sodium and calcium currents of rat ventricular myocytes. Am J Physiol Cell Physiol 270: C645-C649, 1996.