Cloning of an avian adeno-associated virus (AAAV) and generation of recombinant AAAV particles

Journal of Virology

Volumn 77, Issue 12, 2003, Pages 6799-6810

  Bossis, Ioannis ^a   Chiorini, John A ^a,b  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; PALINDROMIC DNA; REPLICATION ASSOCIATED PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ADENO ASSOCIATED VIRUS; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; AVIADENOVIRUS; AVIAN ADENO ASSOCIATED VIRUS; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL LINE; CHICKEN; DNA SEQUENCE; EVOLUTION; GENE SEQUENCE; GENETIC ORGANIZATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; INVERTED TERMINAL REPEAT; LACZ GENE; MOLECULAR CLONING; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN VARIANT; REPORTER GENE; SEQUENCE HOMOLOGY; TANDEM REPEAT; TERMINAL RESOLUTION SITE; VIRUS GENOME; VIRUS PARTICLE; VIRUS RECOMBINANT;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; CELLS, CULTURED; CHICK EMBRYO; CHICKENS; CLONING, MOLECULAR; DEPENDOVIRUS; GENOME, VIRAL; HUMANS; MOLECULAR SEQUENCE DATA; RECOMBINATION, GENETIC; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; TRANSDUCTION, GENETIC; TRANSFECTION; VIRAL PROTEINS; VIRION;

EID: 0038618883     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.12.6799-6810.2003     Document Type: Article

References (70)

1. Astell, C. R. 1990. Terminal hairpins of parvovirus genomes and their role in DNA replication, p. 59-79. In P. Tijssen (ed.), Handbook of parvoviruses. CRC Press, Boca Raton, Fla.
2. Atchison, R. W., B. C. Casto, and W. Hammon. 1965. Adenovirus-associated defective virus particles. Science 149:754-756.
3. Bando, H., J. Kusuda, T. Gojobori, T. Maruyama, and S. Kawase. 1987. Organization and nucleotide sequence of a densovirus genome imply a host-dependent evolution of the parvoviruses. J. Virol. 61:553-560.
4. Bantel-Schall, U., and H. zur Hausen. 1984. Characterization of the DNA of a defective human parvovirus isolated from a genital site. Virology 134:52-63.
5. Bauer, H. J., and G. Monreal. 1986. Herpesviruses provide helper functions for avian adeno-associated parvovirus. J. Gen. Virol. 67:181-185.
6. Bauer, H. J., R. Schneider, H. R. Gelderblom, R. Lurz, V. Friehmelt, and G. Monreal. 1991. Biological and physicochemical characterization of the major (1.40) and minor (1.45) component of infectious avian adeno-associated virus. Arch. Virol. 120:123-133.
7. Berns, K. I., and S. Adler. 1972. Separation of two types of adeno-associated virus particles containing complementary polynucleotide chains. J. Virol. 9:394-396.
8. Berns, K. I., M. Bergoin, M. Bloom, M. Lederman, N. Muzyczka, G. Siegl, J. Tal, and P. Tattersall. 1994. Parvoviridae. Vth report of International Committee on Taxonomy of Viruses, p. 166. In F. A. Murphy, C. M. Faquet, D. H. L. Bishop, S. A. Ghabrial, A. W. Jarvis, G. P. Martelli, M. A. Mayo, and M. D. Summers (ed.), Virus taxonomy. Springer-Verlag, Vienna, Austria.
9. Bohenzky, R. A., R. B. LeFebvre, and K. I. Berns. 1988. Sequence and symmetry requirements within the internal palindromic sequences of the adeno-associated virus terminal repeat. Virology 166:316-327.
10. Boissy, R., and C. R. Astell. 1985. An Escherichia coli recBCsbcBrecF host permits the deletion-resistant propagation of plasmid clones containing the 5′-terminal palindrome of minute virus of mice. Gene 35:179-185.
11. Brister, J. R., and N. Muzyczka. 1999. Rep-mediated nicking of the adenoassociated virus origin requires two biochemical activities, DNA helicase activity and transesterification. J. Virol. 73:9325-9336.
12. Brister, J. R., and N. Muzyczka. 2000. Mechanism of Rep-mediated adenoassociated virus origin nicking. J. Virol. 74:7762-7771.
13. Brown, K. E., S. W. Green, and N. S. Young. 1995. Goose parvovirus - an autonomous member of the dependovirus genus? Virology 210:283-291.
14. Buller, R. M. L., and J. A. Rose. 1978. Characterization of adenovirus-associated virus-induced polypeptides in KB cells. J. Virol. 25:331-338.
15. Chapman, M. S., and M. G. Rossmann. 1993. Structure, sequence and function correlations among parvoviruses. Virology 194:491-508.
16. Chejanovsky, N., and B. J. Carter. 1989. Mutagenesis of an AUG codon in the adeno-associated virus rep gene: effects on viral DNA replication. Virology 173:120-128.
17. Chiorini, J. A., B. Zimmermann, L. Yang, R. H. Smith, A. Ahearn, F. Herberg, and R. M. Kotin. 1998. Inhibition of PrKX, a novel protein kinase, and the cAMP-dependent protein kinase, PKA, by the regulatory proteins of adeno-associated virus type 2. Mol. Cell. Biol. 18:5921-5929.
18. Chiorini, J. A., C. M. Wendtner, E. Urcelay, B. Safer, M. Hallek, and R. M. Kotin. 1995. High-efficiency transfer of the T cell co-stimulatory molecule B7-2 to lymphoid cells using high-titer recombinant adeno-associated virus vectors. Hum. Gene Ther. 6:1531-1541.
19. Chiorini, J. A., F. Kim, L. Yang, and R. M. Kotin. 1999. Cloning and characterization of adeno-associated virus type 5. J. Virol. 73:1309-1319.
20. Chiorini, J. A., L. Yang, Y. Liu, B. Safer, and R. M. Kotin. 1997. Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles. J. Virol. 71:6823-6833.
21. Davidson, B. L., C. S. Stein, J. A. Heth, I. Martins, R. M. Kotin, T. A. Derksen, J. Zabner, A. Ghodsi, and J. A. Chiorini. 2000. Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system. Proc. Natl. Acad. Sci. USA 97:3428-3432.
22. Davis, M. D., J. Wu, and R. A. Owens. 2000. Mutational analysis of adenoassociated virus type 2 Rep68 protein endonuclease activity on partially single-stranded substrates. J. Virol. 74:2936-2942.
23. Di Pasquale, G., and S. N. Stacey. 1998. Adeno-associated virus Rep78 protein interacts with protein kinase A and its homolog PRKX and inhibits CREB-dependent transcriptional activation. J. Virol. 72:7916-7925.
24. El Mishad, A. M., K. J. McCormick, V. J. Yates, and J. J. Trentin. 1975. Detection and serological identification of adeno-associated virus in avian adenovirus stocks. Infect. Immun. 11:287-299.
25. Gao, G. P., M. R. Alvira, L. Wang, R. Calcedo, J. Johnston, and J. M. Wilson. 2002. Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy. Proc. Natl. Acad. Sci. USA 99:11854-11859.
26. Green, M. R., and R. G. Roeder. 1980. Definition of a novel promoter for the major adenovirus-associated virus mRNA. Cell 22:231-242.
27. Green, M. R., and R. G. Roeder. 1980. Transcripts of the adeno-associated virus genome: mapping of the major RNAs. J. Virol. 36:79-92.
28. Henikoff, S., J. G. Henikoff, and S. Pietrokovski. 1999. Blocks+: a nonredundant database of protein alignment blocks derived from multiple compilations. Bioinformatics 15:471-479.
29. Hermonat, P. L., M. A. Labow, R. Wright, K. I. Berns, and N. Muzyczka. 1984. Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutants. J. Virol. 51:329-339.
30. Hess, M., G. Paul, S. Kling, and G. Monreal. 1995. Molecular characterization of two strains of the avian adeno-associated virus (AAAV). Arch. Virol. 140:591-598.
31. Hickman, A. B., D. R. Ronning, R. M. Kotin, and F. Dyda. 2002. Structural unity among viral origin binding proteins: crystal structure of the nuclease domain of adeno-associated virus Rep. Mol. Cell 10:327-337.
32. Hoggan, M. D., N. R. Blacklow, and W. P. Rowe. 1966. Studies of small DNA viruses found in various adenovirus preparations: physical, biological, and immunological characteristics. Proc. Natl. Acad. Sci. USA 55:1467-1474.
33. Im, D. S., and N. Muzyczka. 1992. Partial purification of adeno-associated virus Rep78, Rep52, and Rep40 and their biochemical characterization. J. Virol. 66:1119-1128.
34. Kleinschmidt, J. A., M. Mohler, F. W. Weindler, and R. Heilbronn. 1995. Sequence elements of the adeno-associated virus rep gene required for suppression of herpes-simplex-virus-induced DNA amplification. Virology 206:254-262.
35. Labow, M. A., P. L. Hermonat, and K. I. Berns. 1986. Positive and negative autoregulation of the adeno-associated virus type 2 genome. J. Virol. 60: 251-258.
36. Laughlin, C. A., H. Westphal, and B. J. Carter. 1979. Spliced adenovirusassociated virus RNA. Proc. Natl. Acad. Sci. USA 76:5567-5571.
37. Laughlin, C. A., J. D. Tratschin, H. Coon, and B. J. Carter. 1983. Cloning of infectious adeno-associated virus genomes in bacterial plasmids. Gene 23: 65-73.
38. LeFebvre, R. B., S. Riva, and K. I. Berns. 1984. Conformation takes precedence over sequence in adeno-associated virus DNA replication. Mol. Cell. Biol. 4:1416-1419.
39. Li, J., R. J. Samulski, and X. Xiao. 1997. Role for highly regulated rep gene expression in adeno-associated virus vector production. J. Virol. 71:5236-5243.
40. Lukashov, V. V., and J. Goudsmit. 2001. Evolutionary relationships among parvoviruses: virus-host coevolution among autonomous primate parvoviruses and links between adeno-associated and avian parvoviruses. J. Virol. 75:2729-2740.
41. Lusby, E., K. H. Fife, and K. I. Berns. 1980. Nucleotide sequence of the inverted terminal repetition in adeno-associated virus DNA. J. Virol. 34: 402-409.
42. Lusby, E., R. Bohenzky, and K. I. Berns. 1981. Inverted terminal repetition in adeno-associated virus DNA: independence of the orientation at either end of the genome. J. Virol. 37:1083-1086.
43. Mayor, H. D., K. Torikai, J. L. Melnick, and M. Mandel. 1969. Plus and minus single-stranded DNA separately encapsidated in adeno-associated satellite virions. Science 166:1280-1282.
44. McCarty, D. M., T. H. Ni, and N. Muzyczka. 1992. Analysis of mutations in adeno-associated virus Rep protein in vivo and in vitro. J. Virol. 66:4050-4057.
45. McLaughlin, S. K., P. Collis, P. L. Hermonat, and N. Muzyczka. 1988. Adeno-associated virus general transduction vectors: analysis of proviral structures. J. Virol. 62:1963-1973.
46. Mendelson, E., J. P. Trempe, and B. J. Carter. 1986. Identification of the trans-acting Rep proteins of adeno-associated virus by antibodies to a synthetic oligopeptide. J. Virol. 60:823-832.
47. Muralidhar, S., S. P. Becerra, and J. A. Rose. 1994. Site-directed mutagenesis of adeno-associated virus type 2 structural protein initiation codons: effects on regulation of synthesis and biological activity. J. Virol. 68:170-176.
48. Muramatsu, S. I., H. Mizukami, N. S. Young, and K. E. Brown. 1996. Nucleotide sequence and generation of an infectious clone of adeno-associated virus 3. Virology 221:208-217.
49. Nahreini, P., S. H. Larsen, and A. Srivastava. 1992. Cloning and integration of DNA fragments in human cells via the inverted terminal repeats of the adeno-associated virus 2 genome. Gene 119:265-272.
50. Owens, R. A., M. D. Weitzman, S. R. Kyostio, and B. J. Carter. 1993. Identification of a DNA-binding domain in the amino terminus of adenoassociated virus Rep proteins. J. Virol. 67:997-1005.
51. Parks, W. P., J. L. Melnick., R. Rongey, and H. D. Mayor. 1967. Physical assay and growth cycle studies of a defective adeno-satellite virus. J. Virol. 1:171-180.
52. Pronovost, A. D., V. J. Yates, and D. E. Fry. 1978. Effect of avian adenoassociated virus on pathogenicity of Tipton virus in chicks. Avian Dis. 22: 354-357.
53. Pronovost, A. D., V. J. Yates, and D. E. Fry. 1979. Inhibition and enhancement of avian adenovirus plaque production by heavy and light avian adenovirus-associated viral particles. Am. J. Vet. Res. 40:549-551.
54. Quandt, K., K. Frech, H. Karas, E. Wingender, and T. Werner. 1995. Matlnd and Matlnspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res. 23:4878-4884.
55. Rose, J. A., J. V. Maizel, Jr., J. K. Inman, and A. J. Shatkin. 1971. Structural proteins of adenovirus-associated viruses. J. Virol. 8:766-770.
56. Rutledge, E. A., C. L. Halbert, and D. W. Russell. 1998. Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2. J. Virol. 72:309-319.
57. Ryan, J. H., S. Zolotukhin, and N. Muzyczka. 1996. Sequence requirements for binding of Rep68 to the adeno-associated virus terminal repeats. J. Virol. 70:1542-1553.
58. Samulski, R. J., A. Srivastava, K. I. Berns, and N. Muzyczka. 1983. Rescue of adeno-associated virus from recombinant plasmids: gene correction within the terminal repeats of AAV. Cell 33:135-143.
59. Samulski, R. J., K. I. Berns, M. Tan, and N. Muzyczka. 1982. Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells. Proc. Natl. Acad. Sci. USA 79:2077-2081.
60. Senapathy, P., J. D. Tratschin, and B. J. Carter. 1984. Replication of adenoassociated virus DNA. Complementation of naturally occurring rep 2 mutants by a wild-type genome or an ori 2 mutant and correction of terminal palindrome deletions. J. Mol. Biol. 179:1-20.
61. Smith, R. H., and R. M. Kotin. 1998. The Rep52 gene product of adenoassociated virus is a DNA helicase with 3′-to-5′ polarity. J. Virol. 72:4874-4881.
62. Smith, R. H., and R. M. Kotin. 2000. An adeno-associated virus (AAV) initiator protein, Rep78, catalyzes the cleavage and ligation of singlestranded AAV ori DNA. J. Virol. 74:3122-3129.
63. Smuda, J. W., and B. J. Carter. 1991. Adeno-associated viruses having nonsense mutations in the capsid genes: growth in mammalian cells containing an inducible amber suppressor. Virology 184:310-318.
64. Tratschin, J. D., I. L. Miller, and B. J. Carter. 1984. Genetic analysis of adeno-associated virus: properties of deletion mutants constructed in vitro and evidence for an adeno-associated virus replication function. J. Virol. 51:611-619.
65. Walker, S. L., R. S. Wonderling, and R. A. Owens. 1997. Mutational analysis of the adeno-associated virus Rep68 protein: identification of critical residues necessary for site-specific endonuclease activity. J. Virol. 71:2722-2730.
66. Wonderling, R. S., S. R. M. Kyostio, and R. A. Owens. 1995. A maltosebinding protein/adeno-associated virus rep68 fusion protein has DNA-RNA helicase and ATPase activities. J. Virol. 69:3542-3548.
67. Xie, Q., W. Bu, S. Bhatai, J. Hare, T. Somasundaram, A. Azzi, and M. S. Chapman. 2002. The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy. Proc. Natl. Acad. Sci. USA 99:10405-10410.
68. Yates, V. J., A. M. el-Mishad, K. J. McCormick, and J. J. Trentin. 1973. Isolation and characterization of an avian adenovirus-associated virus. Infect. Immun. 7:973-980.
69. Yates, V. J., G. J. Dawson, and A. D. Pronovost. 1981. Serologic evidence of avian adeno-associated virus infection in an unselected human population and among poultry workers. Am. J. Epidemiol. 113:542-545.
70. Zadori, Z., R. Stefancsik, T. Rauch, and J. Kisary. 1995. Analysis of the complete nucleotide sequences of goose and muscovy duck parvoviruses indicates common ancestral origin with adeno-associated virus 2. Virology 212:562-573.