Highly diastereoselective 1,3-dipolar cycloaddition reactions of trans-2-methylene-1,3-dithiolane 1,3-dioxide with 3-oxidopyridinium and 3-oxidopyrylium betaines: A route to the tropane skeleton

Organic and Biomolecular Chemistry

Volumn 1, Issue 11, 2003, Pages 1884-1893

  Aggarwal, Varinder K ^a   Grainger, Richard S ^b   Newton, Gary K ^b   Spargo, Peter L ^c   Hobson, Adrian D ^d   Adams, Harry ^b  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^d ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITION REACTIONS; ISOMERS; MOLECULAR STRUCTURE; NITROGEN; REACTION KINETICS; SUBSTITUTION REACTIONS;

DIASTEREOSELECTIVE; OXIDOPYRIDINIUM; OXIDOPYRYLIUM BETAINES; TRANS METHYLENE DITHIOLANE DIOXIDE; TROPANE SKELETON;

AROMATIC COMPOUNDS;

3 OXIDOPYRIDINIUM BETAINE; 3-OXIDOPYRIDINIUM BETAINE; BETAINE; PYRIDINIUM DERIVATIVE; SULFOXIDE; TRITYL DERIVATIVE; TROPANE DERIVATIVE; VINYL DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOISOMERISM; SYNTHESIS;

BETAINE; CYCLIZATION; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PYRIDINIUM COMPOUNDS; STEREOISOMERISM; SULFOXIDES; TRITYL COMPOUNDS; TROPANES; VINYL COMPOUNDS;

EID: 0038603123     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b302834h     Document Type: Article

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