Role of Ca2+ stores in metabotropic L-glutamate receptor-mediated supralinear Ca2+ signaling in rat hippocampal neurons

Journal of Neuroscience

Volumn 20, Issue 23, 2000, Pages 8628-8636

  Rae, M G ^a   Martin, D J ^a   Collingridge, G L ^a   Irving, A J ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Ca2+ release; Ca2+ stores; mGlu; NMDA; Recency detector; Supralinear

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 3,5 DIHYDROXYPHENYLGLYCINE; CALCIUM CHANNEL L TYPE; CALCIUM ION; GLUTAMATE RECEPTOR; METABOTROPIC RECEPTOR; NIFEDIPINE; POTASSIUM ION; UNCLASSIFIED DRUG; 3,5-DIHYDROXYPHENYLGLYCINE; AMINO ACID RECEPTOR BLOCKING AGENT; CAFFEINE; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; DRUG DERIVATIVE; ENZYME INHIBITOR; GLYCINE; METABOTROPIC RECEPTOR 5; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYLASPARTIC ACID; POTASSIUM; RESORCINOL DERIVATIVE;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL CULTURE; CHANNEL GATING; CONTROLLED STUDY; DEPOLARIZATION; HIPPOCAMPUS; NERVE CELL; NONHUMAN; POTASSIUM CELL LEVEL; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION; ACTION POTENTIAL; ANIMAL; CYTOLOGY; DRUG ANTAGONISM; DRUG CONTRAINDICATION; DRUG EFFECT; DRUG POTENTIATION; EXTRACELLULAR SPACE; GLIA; METABOLISM; PATCH CLAMP; PHYSIOLOGY;

ACTION POTENTIALS; ANIMALS; CAFFEINE; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CELLS, CULTURED; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; EXTRACELLULAR SPACE; GLYCINE; HIPPOCAMPUS; N-METHYLASPARTATE; NEUROGLIA; NEURONS; PATCH-CLAMP TECHNIQUES; POTASSIUM; RATS; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; RESORCINOLS;

EID: 0034353645     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-23-08628.2000     Document Type: Article

References (59)

1. 2+ signals induced in hippocampal CA1 neurones by the synaptic activation of NMDA receptors
2. The role of divalent cations in the N-methyl-D-aspartate responses of mouse central neurones in culture
3. Long-term depression in the hippocampus
4. 2+ signalling in hippocampal astrocytes
5. Neuronal calcium signaling
6. 3- and calcium-gated channels from endoplasmic reticulum of cerebellum
7. 2+ rises in hippocampal pyramidal cells
8. A synaptic model of memory: Long-term potentiation in the hippocampus
9. Roles of metabotropic glutamate receptors in LTP and LTD in the hippocampus
10. 2+ spikes
11. Modulatory effects of NMDA on phosphoinositide responses evoked by the metabotropic glutamate receptor agonist 1S,3R-ACPD in neonatal rat cerebral cortex
12. Pharmacology and functions of metabotropic glutamate receptors
13. Single synaptic events evoke NMDA receptor-mediated release of calcium from internal stores in hippocampal dendritic spines
14. Calcium on the up: Supralinear calcium signaling in central neurons
15. Activation of group I mGluRs potentiate NMDA responses in rat hippocampal slices
16. Metabotropic glutamate receptors and calcium signalling in dendrites of hippocampal CA1 neurones
17. Synaptic tagging and long-term potentiation
18. 2+](i)
19. Release and sequestration of calcium by ryanodine-sensitive stores in rat hippocampal neurons
20. 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist
21. 2+ indicators with greatly improved fluorescence properties
22. Signal transduction pathways involved in the acute potentiation of NMDA responses by 1S,3R-ACPD in rat hippocampal slices
23. 2+ mobilisation in cultured rat hippocampal neurons
24. 2+ sensitivities
25. Glutamate activates multiple single channel conductances in hippocampal neurons
26. 2+ release signals in NGF-differentiated PC12 cells and hippocampal neurons
27. 2+ signals in spines of hippocampal neurons
28. 1 pituitary cells
29. Potentiation of a metabotropic glutamatergic response following NMDA receptor activation in rat hippocampus
30. 2+ entry through the N-methyl-D-aspartate channel
31. 2+ of NMDA responses in spinal cord neurones
32. Agonist- and voltage-gated calcium entry in cultured mouse spinal cord neurons under voltage clamp measured using arsenazo III
33. 2+ entry channel
34. 2+ release from intracellular stores induced by afferent stimulation of CA3 pyramidal neurons in hippocampal slices
35. 2+ in permeabilized cells
36. 2+ entry through basal membrane
37. 2+ homeostasis in hippocampal neurons in vitro
38. 3-sensitive stores evoked by synaptic activation of mGluRs paired with backpropagating action potentials
39. Magnesium gates glutamate-activated channels in mouse central neurones
40. Store depletion and calcium influx
41. 2+ entry via synaptically activated NMDA receptors in the induction of long-term potentiation
42. 2+ transients in dendritic spines of hippocampal pyramidal neurons in brain slice
43. A model for receptor-regulated calcium entry
44. Calcium concentration dynamics produced by synaptic activation of CA1 hippocampal pyramidal cells
45. Localisation of the glutamate receptor subunit GluR1 on the surface of living and within cultured hippocampal neurones
46. NMDA receptors amplify calcium influx into dendritic spines during associative pre- and postsynaptic activation
47. 2+](i) in cultured rat hippocampal neurons following exposure to N-methyl-D-aspartate
48. 2+ stores in peripheral and central mammalian neurons
49. 2+
50. 2+-release microdomains in cultured glia
51. 2+ release channels of sheep cardiac sarcoplasmic reticulum
52. Blockade of long-term potentiation in rat hippocampal CA1 region by inhibitors of protein synthesis
53. A new class of synapt c response involving calcium release in dendritic spines
54. 2+ stores
55. 2+ stores
56. When are class I metabotropic glutamate receptors necessary for long-term potentiation?
57. 2+ oscillations activated by mGluRs in hippocampal stratum oriens/alveus interneurons
58. Multiple forms of LTP in hippocampal CA3 neurons use a common postsynaptic mechanism
59. Mechanisms, of calcium influx into hippocampal spines: Heterogeneity among spines, coincidence detection by NMDA receptors, and optical quantal analysis