Effects of repeated withdrawal episodes, nicotine dose, and duration of nicotine exposure on the severity and duration of nicotine withdrawal in rats

Psychopharmacology

Volumn 168, Issue 3, 2003, Pages 280-292

  Skjei, Karen L ^a,b   Markou, Athina ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Dihydro erythroidine; Dose; Duration; Intracranial self stimulation; Nicotine; Rat; Repeated; Reward; Somatic signs; Withdrawal

Indexed keywords

DIHYDRO BETA ERYTHROIDINE; NICOTINE TARTRATE; NICOTINIC RECEPTOR BLOCKING AGENT; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; BRAIN DEPTH STIMULATION; CIGARETTE SMOKING; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; DRUG EXPOSURE; MALE; NONHUMAN; OSMOTIC MINIPUMP; PRIORITY JOURNAL; RAT; REWARD; SELF STIMULATION; SMOKING CESSATION; WITHDRAWAL SYNDROME;

ANIMALS; CENTRAL NERVOUS SYSTEM STIMULANTS; DIHYDRO-BETA-ERYTHROIDINE; DOSE-RESPONSE RELATIONSHIP, DRUG; INFUSION PUMPS, IMPLANTABLE; MALE; NICOTINE; NICOTINIC ANTAGONISTS; RATS; RATS, WISTAR; REWARD; SELF STIMULATION; SENSORY THRESHOLDS; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 0038581464     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-003-1414-1     Document Type: Article

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