Preparation and antitumor effect of drug delivery system of taxol conjugated to polyethylene glycol

Huagong Xuebao/Journal of Chemical Industry and Engineering (China)

Volumn 54, Issue 2, 2003, Pages 209-214

  Feng, Xia ^a   Liang, Shile ^a   Li, Xiaofeng ^a   Yuan, Yingjin ^a  

^a TIANJIN UNIVERSITY   (China)

Author keywords

DDS; In vitro antitumor activity; Taxol; Water soluble

Indexed keywords

POLYETHYLENE GLYCOLS; POLYMERS; SOLUBILITY; TUMORS; WOOD PRODUCTS;

ANTITUMOR ACTIVITY; DRUG DELIVERY SYSTEM; TAXOL; WATER SOLUBLE;

DRUG THERAPY;

EID: 0038545725     PISSN: 04381157     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Wani M C, Taylor H L, Wall M E. Coggon P, McPhail A T. Plant Antitumor Agent VI. The Isolation and Structure of Taxol, a Novel Antileukemic and Antitumor Agent Taxus Brevifolia. J. Am. Chem. Soc., 1971, 93: 2325-2327
2. Zhang Changping, Li Chun, Yuan Yingjin. Effects of Fungal Elicitor on Secondary Metabolism of Cell Suspension Culture of Taxus Chinensis var. mairei. Journal of Chemical Industry and Engineering (China), 2002, 53 (5): 498-502
3. Li Chun, Yuan Yingjin, Ma Zhonghai, Hu Zongding. Changes of Physiological State of Suspension Culture of Taxus Chinensis var. mairei Induced by Oligosaccharide. Journal of Chemical Industry and Engineering (China), 2002, 53 (11): 1133-1138
4. Vyas D M, Wong H, Crosswell A R. Synthesis and Antitumor Evaluation of Water Soluble Taxol Phosphates. Bioorg. Med. Chem. Lett., 1993, 3: 1357-1360
5. Rowinsk E K, Donehower R C. Paclitaxel (Taxol). New Engl. J. Med., 1995, 332: 1004-1014
6. Panchagnula R. Pharmaceutical Aspects of Paclitaxel. Int. J. Pharm., 1998, 172: 1-15
7. Adlakha-Hutcheon G, Bally M B, Shew C R, Madden T D. Controlled Destabilization of a Liposomal Drug Delivery System Enhances Mitoxantrone Antitumor Activity. Nature Biotech. 1999, 17: 775-779
8. Cortesi R, Nastruzzi C. Liposomes, Microemulsions as New Delivery Systems for Cytotoxic Alkaloids. PSTT, 1999, 2 (7): 288-298
9. Admen S B. Biodegradable Polymers for Delivery of Proteins and Water-Insoluble Drugs. Investigational New Drugs, 1994, 12: 169-182
10. Sharma A, Straubinger R M. Novel Taxol Formulations: Preparation and Characterization of Taxol-Containing Liposomes. Pharm. Res., 1994, 11: 889-896
11. Rodrigues M, Carter P, Wirth C, Mullins S, Lee A, Blackburn B K. Synthesis and β-lactamase-Mediated Activation of Cepphalosporin-Taxol Prodrug. Chem. Biol., 1995, 2: 223-227
12. Dosio F, Brusa P, Crosasso P, Arpicco S, Cattel L. Preparation, Characterization and Properties in Vitro and Vivo of Paclitaxel-Albumin Conjugate. J. Control Release, 1997, 47: 293-304
13. Tarr B D, Sambandan T G, Yalkowsky S H. A New Parenteral Emulsion for the Administration of Taxol. Pharm. Res., 1987, 4: 162-165
14. Bartoli H, Boitard M, Fessi H, Beriel H, Devissagnet J P, Picot F, Puisien F. In Vitro and in Vivo Antitumoral Activity of Free and Encapsulated Taxol. J. Microencapsulation, 1990, 7: 191-197
15. Burt H, Jackson J K, Sarvjeet B K. Controlled Delivery of Taxol from Microspheres Composed of Blend of Ethylene-Vinyl Acetate Copolymer and Poly (d,l-lactic acid), Cancer Lett., 1995, 88: 73-79
16. Sharma U S, Blasubramanian S V, Straubinger R M. Pharmaceutical and Physical Properties of Paclitaxel (Taxol) Complexes with Cyclodextrins. J. Pharm. Sci., 1995, 84: 1223-1230
17. Yuan Yingjin, Li Jinliang, CN 1283643A [P]. 2001
18. Han Rui. Chemical Preventive and Drug Treatment of Tumor. Beijing: Beijing Medicinal University Press, 1991. 16
19. Greenwald R B, Pendri A, Bolikal D. Highly Water Soluble Taxol Derivatives: 7-Polyethylene Glycol Carbamates and Carbonates. J. Org. Chem., 1995, 60: 331-336
20. Nicolaou K C, Guy R K, Pitsinos E N, Wrasidlo. A Water Soluble Prodrugs of Taxol with Self-Assembling Properties. Angew. Chem. Int., 1994, 33: 1583-1587