Contributions of nitric oxide, EDHF, and EETS to endothelium-dependent relaxation in renal afferent arterioles

Kidney International

Volumn 63, Issue 6, 2003, Pages 2187-2193

  Wang, Dan ^b   Borrego Conde, Lillian J ^b   Falck, John R ^b   Sharma, Kamalesh K ^b   Wilcox, Christopher S ^b   Umans, Jason G ^a  

^a GEORGETOWN UNIVERSITY   (United States)

^b NONE

Author keywords

14,15 epoxyeicosa 5(Z) enoic acid; Calcium activated potassium channel; Endothelium dependent hyperpolarizing factor; Endothelium derived relaxing factor; Epoxyeicosatrienoic acids; Soluble guanylyl cyclase

Indexed keywords

14,15 EPOXY 5,8,11 ICOSATRIENOIC ACID; ACETYLCHOLINE; APAMIN; CALCIUM ACTIVATED POTASSIUM CHANNEL; CHARYBDOTOXIN; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; GUANYLATE CYCLASE; INDOMETACIN; METHYLENE BLUE; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NORADRENALIN; POTASSIUM CHLORIDE; PROSTAGLANDIN SYNTHASE;

ANIMAL TISSUE; ARTERIOLE; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME INHIBITION; KIDNEY BLOOD VESSEL; MALE; NONHUMAN; PERFUSION; PRIORITY JOURNAL; RABBIT; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM; VASOCONSTRICTION; VASODILATATION;

EID: 0038527272     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2003.00036.x     Document Type: Article

References (43)

1. GARLAND C, PLANE F, KEMP B, COCKS T: Endothelium-dependent hyperpolarization: A role in the control of vascular tone. Trends Pharmacol Sci 16:23-30, 1995
2. 2+ during acetylcholine-induced dilation of microvessels. Br J Pharmacol 128:124-134, 1999
3. CAMPBELL WB, FALCK JR, GAUTHIER K: Role of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factor in bovine coronary arteries. Med Sci Monit 7:578-584, 2001
4. RANDALL MD, KENDALL DA: Involvement of a cannabinoid in endothelium-derived hyperpolarizing factor-mediated coronary vasorelaxation. Eur J Pharmacol 335:205-209, 1997
5. + is an endothelium-derived hyperpolarizing factor in rat arteries. Nature 396:269-272, 1998
6. MATOBA T, SHIMOKAWA H, NAKASHIMA M, et al: Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice. J Clin Invest 106:1521-1530, 2000
7. MATOBA, T, SHIMOKAWA H, KUBOTA H, et al: Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in human mesenteric arteries. Biochem Biophys Res Commun 290:909-913, 2002
8. FURCHGOTT R, ZAWADZKI J: The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288:373-376, 1980
9. ARCHER SL, HUANG JMC, HAMPL V: Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K+ channel by cGMP-dependent protein kinase. Proc Natl Acad Sci USA 91:7583-7587, 1994
10. TARE M, PARKINGTON HC, COLEMAN HA, et al: Hyperpolarization and relaxation of arterial smooth muscle caused by nitric oxide derived from the endothelium. Nature 346:69-71, 1990
11. 2+ in relation to generation of acetylcholine-dependent hyperpolarization in rat mesenteric artery. Br J Pharmacol 120:1328-1334, 1997
12. CAMPBELL WB, GEBREMEDHIN D, PRATT PF, HARDER DR: Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. Circ Res 78:415-423, 1996
13. GAUTHIER KM, DEETER C, KRISHNA UM, et al: 14,15-Epoxyeicosa-5(Z)-enoic acid: a selective epoxyeicosatrienoic acid antagonist that inhibits endothelium-dependent hyperpolarization and relaxation in coronary arteries. Circ Res 90:1028-1036, 2002
14. ITO S, JUNCOS LA, NUSHIRO N, et al: Endothelium-derived relaxing factor modulates endothelin action in afferent arterioles. Hypertension 17:1052-1056, 1991
15. JUNCOS LA, ITO S, CARRETERO OA, GARVIN JL: Removal of endothelium-dependent relaxation by antibody and complement in afferent arterioles. Hypertension 23:I54-I59, 1994
16. + channels. Cell Calcium 4:421-428, 1983
17. GIMENEZ-GALLEGO G, NAVIA MA, REUBEN JP, et al: Purification, sequence, and model structure of charybdotoxin, a potent selective inhibitor of calcium-activated potassium channels. Proc Natl Acad Sci USA 85:3329-3333, 1988
18. COHEN RA, PLANE F, NAJIBI S, et al: Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit carotid artery. Proc Natl Acad Sci USA 94:4193-4198, 1997
19. WANG X, LOUTZENHISER R: Determinants of renal microvascular response to ACh: Afferent and efferent arteriolar actions of EDHF. Am J Physiol Renal Physiol 282:F124-F132, 2002
20. ITO S, ARIMA S, REN YL, et al: Endothelium-derived relaxing factor/nitric oxide modulates angiotensin II action in the isolated perfused rabbit afferent but not efferent arteriole. J Clin Invest 91:2012-2019, 1993
21. FUJIMOTO S, ITOH T: Role of nitric oxide and nitric oxide-independent relaxing factor in contraction and relaxation of rabbit blood vessels. Eur J Pharmacol 330:177-184, 1997
22. EDWARDS RM: Response of isolated renal arterioles to acetylcholine, dopamine, and bradykinin. Am J Physiol 248:F183-F189, 1985
23. JUNCOS LA, REN YL, ARIMA S, ITO S: Vasodilator and constrictor actions of platelet-activating factor in the isolated microperfused afferent arteriole of the rabbit kidney. Role of endothelium-derived relaxing factor/nitric oxide and cyclooxygenase products. J Clin Invest 91:1374-1379, 1993
24. SCHNACKENBERG CG, WILCOX CS: The SOD mimetic tempol restores vasodilation in afferent arterioles of experimental diabetes. Kidney Int 59:1859-1864, 2001
25. RAPOPORT RM, MURAD F: Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP. Circ Res 52:352-357, 1983
26. KELM M, SCHRADER J: Control of coronary vascular tone by nitric oxide. Circ Res 66:1561-1575, 2001
27. TROTTIER G, TRIGGLE CR, O'NEIL SK, LOUTZENHISER R: Cyclic GMP-dependent and cyclic GMP-independent actions of nitric oxide on the renal afferent arteriole. Br J Pharmacol 125:563-569, 1998
28. IGNARRO LJ, WOOD KS, BURKE TM, et al: Association between cyclic GMP accumulation and acetylcholine-elicited relaxation of bovine intrapulmonary artery. J Pharmacol Exp Ther 228:682-690, 1984
29. NAGAO T, VANHOUTTE PM: Hyperpolarization as a mechanism for endothelium-dependent relaxation in the porcine coronary artery. J Physiol 445:355-367, 1992
30. BOLZ SS, FISSLTHALER B, PIEPERHOFF S, et al: Antisense oligonucleotides against cytochrome P450 2C8 attenuate EDHF-mediated Ca (2+) changes and dilation in isolated resistance arteries. FASEB J 14:255-260, 2000
31. + channel. J Pharmacol Exp Ther 285:659-664, 1998
32. MCGUIRE JJ, DING H, TRIGGLE CR: Endothelium-derived relaxing factors: A focus on endothelium-derived hyperpolarizing factor(s). Can J Physiol Pharmacol 79:443-470, 2001
33. SCHWEITZ H, STANSFELD CE, BIDARD JN, et al: Charybdotoxin blocks dendrotoxin-sensitive voltage-activated K+ channels. FEBS Lett 250:519-522, 1989
34. ROMAN RJ: P-450 metabolites of arachidonic acid in the control of cardiovascular function. Physiol Rev 82:131-185, 2002
35. GEBREMEDHIN D, MA YH, FALCK JR, et al: Mechanism of action of cerebral epoxyeicosatrienoic acids on cerebral arterial smooth muscle. Am J Physiol 263:H519-H525, 1992
36. IMIG JD, NAVAR LG, ROMAN RJ, et al: Actions of epoxygenase metabolites on the preglomerular vasculature. J Am Soc Nephrol 7:2364-2370, 1996
37. IMIG JD, FALCK JR, WEI S, CAPDEVILA JH: Epoxygenase metabolites contribute to nitric oxide-independent afferent arteriolar vasodilation in response to bradykinin. J Vasc Res 38:247-255, 2001
38. TRIGGLE CR, DONG H, WALDRON GJ, COLE WC: Endothelium-derived hyperpolarizing factor(s): Species and tissue heterogeneity. Clin Exp Pharmacol Physiol 26:176-179, 1999
39. DOUGHTY JM, PLANE F, LANGTON PD: Charybdotoxin and apamin block EDHF in rat mesenteric artery if selectively applied to the endothelium. Am J Physiol 276:H1107-H1112, 1999
40. PASCOAL IF, UMANS JG: Effect of pregnancy on mechanisms of relaxation in human omental microvessels. Hypertension 28:183-187, 1996
41. DENG LY, LI JS, SCHIFFRIN EL: Endothelium-dependent relaxation of small arteries from essential hypertensive patients: mechanisms and comparison with normotensive subjects and with responses of vessels from spontaneously hypertensive rats. Clin Sci Lond 88:611-622, 1995
42. SHIMOKAWA H, YASUTAKE H, FUJII K, et al: The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation. J Cardiovasc Pharmacol 28:703-711, 1996
43. WELCH WJ, WILCOX CS: What is brain nitric oxide synthase doing in the kidney? Curr Opin Nephrol Hypertens 11:109-115, 2002