Does the beneficial effect of HRT on endothelial function depend on lipid changes

Maturitas

Volumn 45, Issue 1, 2003, Pages 47-54

  Ossewaarde, Marlies E ^a   Bots, Michiel L ^a   Van Der Schouw, Yvonne T ^a   De Kleijn, Miriam J J ^a   Wilmink, Hanneke W ^a   Bak, Annette A A ^a   Planellas, Juan ^b   Banga, Jan Dirk ^a   Grobbee, Diederick E ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b NV ORGANON   (Netherlands)

Author keywords

Blood pressure; Endothelial function; Hormone replacement therapy; Lipids

Indexed keywords

CHOLESTEROL; CONJUGATED ESTROGEN PLUS MEDROXYPROGESTERONE ACETATE; GLYCERYL TRINITRATE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LIPOPROTEIN A; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TIBOLONE; TRIACYLGLYCEROL;

ADULT; ARTERY BLOOD FLOW; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; BLOOD PRESSURE MONITORING; BRACHIAL ARTERY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; HORMONE SUBSTITUTION; HUMAN; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL;

EQUIDAE;

EID: 0038513838     PISSN: 03785122     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5122(03)00085-9     Document Type: Article

References (48)

1. Rijpkema A.H., van der Sanden A.A., Ruijs A.H. Effects of post-menopausal oestrogen-progestogen replacement therapy on serum lipids and lipoproteins: a review. Maturitas. 12:1990;259-285.
2. Bush T.L., Barrett-Connor E., Cowan L.D., et al. Cardiovascular mortality and noncontraceptive use of estrogen in women: results from the Lipid Research Clinics Program Follow-up Study. Circulation. 75:1987;1102-1109.
3. McGrath B.P., Liang Y.L., Teede H., Shiel L.M., Cameron J.D., Dart A. Age-related deterioration in arterial structure and function in postmenopausal women: impact of hormone replacement therapy. Arterioscler. Thromb. Vasc. Biol. 18:1998;1149-1156.
4. Muscat B.Y., Brincat M., Galea R. Carotid artery wall thickness in women treated with hormone replacement therapy. Maturitas. 27:1997;47-53.
5. Westendorp I.C., de Kleijn M.J., Bots M.L., et al. The effect of hormone replacement therapy on arterial distensibility and compliance in perimenopausal women: a 2-year randomised trial. Atherosclerosis. 152:2000;149-157.
6. Lieberman E.H., Gerhard M.D., Uehata A., et al. Estrogen improves endothelium-dependent, flow-mediated vasodilation in postmenopausal women. Ann. Intern. Med. 121:1994;936-941.
7. McCrohon J.A., Adams M.R., McCredie R.J., et al. Hormone replacement therapy is associated with improved arterial physiology in healthy post-menopausal women. Clin. Endocrinol. (Oxf.). 45:1996;435-441.
8. de Kleijn M.J.J., Wilmink H.W., Bots M.L., et al. Hormone replacement therapy and endothelial function. Atherosclerosis. 159:2001;357-365.
9. Gilligan D.M., Badar D.M., Panza J.A., Quyyumi A.A., Cannon R.O. Acute vascular effects of estrogen in postmenopausal women. Circulation. 90:1994;786-791.
10. Gerhard M., Walsh B.W., Tawakol A., et al. Estradiol therapy combined with progesterone and endothelium-dependent vasodilation in postmenopausal women. Circulation. 98:1998;1158-1163.
11. Anderson R.A., Evans L.M., Ellis G.R., Jackson S.K., Lewis M.J., Rees A. Post-prandial lipaemia is associated with increased free radicals and deterioration in endothelial function in non-insulin-dependent diabetes. Eur. Heart J. A3305:2000;576.
12. Iiyama K., Nagano M., Yo Y., et al. Impaired endothelial function with essential hypertension assessed by ultrasonography. Am. Heart J. 132:1996;779-782.
13. Jarvisalo M.J., Toikka J.O., Vasankari T., et al. HMG CoA reductase inhibitors are related to improved systemic endothelial function in coronary artery disease. Atherosclerosis. 147:1999;237-242.
14. Higashi Y., Oshima T., Sasaki S., et al. Angiotensin-converting enzyme inhibition, but not calcium antagonism, improves a response of the renal vasculature to L-arginine in patients with essential hypertension. Hypertension. 32:1998;16-24.
15. Dupuis J., Tardif J.C., Cernacek P., Theroux P. Cholesterol reduction rapidly improves endothelial function after acute coronary syndromes. The RECIFE (reduction of cholesterol in ischemia and function of the endothelium) trial. Circulation. 99:1999;3227-3233.
16. Wilmink H.W., Stroes E.S., Erkelens D.W., et al. Influence of folic acid on postprandial endothelial dysfunction. Arterioscler. Thromb. Vasc. Biol. 20:2000;185-188.
17. Grieve D.J., Avella M.A., Elliott J., Botham K.M. The influence of chylomicron remnants on endothelial cell function in the isolated perfused rat aorta. Atherosclerosis. 139:1998;273-281.
18. Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18:1972;499-502.
19. Venrooij van F.V., Van De Ree M.A., Bots M.L., Stolk R.P., Huisman M.V., Banga J.D. Aggressive lipid lowering does not improve endothelial function in Type 2 diabetes: the diabetes atorvastatin lipid intervention (DALI) study: a randomized, double-blind, placebo-controlled trial. Diabetes Care. 25:2002;1211-1216.
20. Roos de N.M., Bots M.L., Katan M.B. Replacement of dietary saturated fatty acids by trans fatty acids lowers serum HDL cholesterol and impairs endothelial function in healthy men and women. Arterioscl. Thromb. Vasc. Biol. 21:2001;1233-1237.
21. Bots M.L., Remme W.J., Luscher T.F., Grobbee D.E. Perindopril - function of the endothelium in Coronary Artery Disease: The PERFECT study - substudy of EUROPA: rationale and design. Cardiovasc. Drugs Therap. 16:2002;227-236.
22. Kuvin J.T., Patel A.R., Karas R.H. Need for standardization of noninvasive assessment of vascular endothelial function. Am. Heart J. 141:2001;327-328.
23. Taddei S., Virdis A., Ghiadoni L., Mattei P., Sudano I., Bernini G., et al. Menopause is associated with endothelial dysfunction in women. Hypertension. 28:1996;576-582.
24. Vogel R.A. Coronary risk factors, endothelial function, and atherosclerosis: a review. Clin. Cardiol. 20:1997;426-432.
25. Sorensen K.E., Dorup I., Hermann A.P., Mosekilde L. Combined hormone replacement therapy does not protect women against the age-related decline in endothelium-dependent vasomotor function. Circulation. 97:1998;1234-1238.
26. van Baal W.M., Kenemans P., Emeis J.J., et al. Long-term effects of combined hormone replacement therapy on markers of endothelial function and inflammatory activity in healthy postmenopausal women. Fertil. Steril. 71:1999;663-670.
27. Lekakis J, Papamichael C, Mavrikakis M, Voutsas A, Stamatelopoulos S. Effect of long-term estrogen therapy on brachial arterial endothelium-dependent vasodilation in women with Raynaud's phenomenon secondary to systemic sclerosis, Am J Cardiol 1998;82:1555-557, A8.
28. Schachinger V., Britten M.B., Zeiher A.M. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation. 101:2000;1899-1906.
29. Suwaidi J.A., Hamasaki S., Higano S.T., Nishimura R.A., Holmes D.R. Jr, Lerman A. Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction. Circulation. 101:2000;948-954.
30. Anderson T.J., Uehata A., Gerhard M.D., et al. Close relation of endothelial function in the human coronary and peripheral circulations. J. Am. Coll. Cardiol. 26:1995;1235-1241.
31. Nascimento C.A., Kauser K., Rubanyi G.M. Effect of 17beta-estradiol in hypercholesterolemic rabbits with severe endothelial dysfunction. Am. J. Physiol. 276:1999;H1788-H1794.
32. Wilmink H.W., de Kleijn M.J.J., Bots M.L., et al. Lipoprotein (a) is associated with endothelial function in healthy postmenopausal women. Atherosclerosis. 153:2000;249-254.
33. Sorensen K.E., Celermajer D.S., Georgakopoulos D., Hatcher G., Betteridge D.J., Deanfield J.E. Impairment of endothelium-dependent dilation is an early event in children with familial hypercholesterolemia and is related to the lipoprotein(a) level. J. Clin. Invest. 93:1994;50-55.
34. de Roos NM, Bots ML, Schouten EG, Katan MB. Within-subject variability in flow-mediated vasodilatation of the brachial artery in healthy men and women. Thesis, Agricultural University, Wageningen, 2001.
35. Stein J.H., Rosenson R.S. Lipoprotein Lp(a) excess and coronary heart disease. Arch. Intern. Med. 157:1997;1170-1176.
36. Scanu A.M. Atherothrombogenicity of lipoprotein(a): the debate. Am. J. Cardiol. 82:1998;26Q-33Q.
37. Schachinger V., Halle M., Minners J., Berg A., Zeiher A.M. Lipoprotein(a) selectively impairs receptor-mediated endothelial vasodilator function of the human coronary circulation. J. Am. Coll. Cardiol. 30:1997;927-934.
38. Jenner J.L., Ordovas J.M., Lamon-Fava S., et al. Effects of age, sex, and menopausal status on plasma lipoprotein(a) levels. Circulation. 87:1993;1135-1141.
39. Lepre F., Campbell B., Crane S., Hickman P. Low-dose sustained release nicotinic acid (Tri-B3) and lipoprotein (a) (letter). Am. J. Cardiol. 70:1992;133.
40. Shlipak M.G., Simon J.A., Vittinghoff E., et al. Estrogen and progestin, lipoprotein(a), and the risk of recurrent coronary heart disease events after menopause. J. Am. Med. Assoc. 283:2000;1845-1852.
41. Davignon J., Laaksonen R. Low-density lipoprotein-independent effects of statins. Curr. Opin. Lipidol. 10:1999;543-559.
42. Williams J.K., Sukhova G.K., Herrington D.M., Libby P. Pravastatin has cholesterol-lowering independent effects on the artery wall of atherosclerotic monkeys. J. Am. Coll. Cardiol. 31:1998;684-691.
43. Vogel R.A. Brachial artery ultrasound: a noninvasive tool in the assessment of triglyceride-rich lipoproteins. Clin. Cardiol. 22:1999;II34-II39.
44. Valk-de Roo G.W., Stehouwer C.D., Lambert J., et al. Plasma homocysteine is weakly correlated with plasma endothelin and von Willebrand factor but not with endothelium-dependent vasodilatation in healthy postmenopausal women. Clin. Chem. 45:1999;1200-1205.
45. Walsh B.W., Paul S., Wild R.A., et al. The effects of hormone replacement therapy and raloxifene on C-reactive protein and homocysteine in healthy postmenopausal women: a randomized, controlled trial. J. Clin. Endocrinol. Metab. 85:2000;214-218.
46. Rosano G.M., Panina G. Oestrogens and the heart. Therapy. 54:1999;381-385.
47. Pripp U., Hall G., Csemiczky G., Eksborg S., Landgren B.M., Schenck-Gustafsson K.A. Randomized trial on effects of hormone therapy on ambulatory blood pressure and lipoprotein levels in women with coronary artery disease. J. Hypertens. 17:1999;1379-1386.
48. Sorensen M.B., Rasmussen V., Jensen G., Ottesen B. Temporal changes in clinic and ambulatory blood pressure during cyclic post-menopausal hormone replacement. J. Hypertens. 18:2000;1387-1391.