T-cell signal transduction in children with cow's milk allergy - Increased MAP kinase activation in patients with acute symptoms of cow's milk allergy

Pediatric Allergy and Immunology

Volumn 14, Issue 3, 2003, Pages 163-168

  Österlund, Pamela ^a   Von Willebrand, Maria ^a,b   Andersson, Leif C ^b   Suomalainen, Hanna ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Cow's milk allergy; Infants; MAP kinase activity

Indexed keywords

CONCANAVALIN A; GAMMA INTERFERON; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; INFANT; MALE; MILK ALLERGY; NEWBORN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

BLOTTING, WESTERN; HUMANS; IMMUNOGLOBULIN E; INFANT; INFANT, NEWBORN; MILK HYPERSENSITIVITY; MITOGEN-ACTIVATED PROTEIN KINASE 1; PHOSPHORYLATION; PROSPECTIVE STUDIES; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SKIN TESTS;

EID: 0038509997     PISSN: 09056157     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3038.2003.00026.x     Document Type: Conference Paper

References (15)

1. SAVILAHTI E, HEYMAN M, MACDONALD T, et al. Diagnostic criteria for food allergy with predominantly intestinal symptoms. J Pediatr Gastroenterol Nutr 1992: 14: 108-12.
2. JAKOBSSON I, LINDBERG T. Cow's milk as a cause of infantile colic in breast-fed infants. Lancet 1978: 2: 437-9.
3. WARNER JO. Food allergy in fully breast-fed infants. Clin Allergy 1980: 10: 133-6.
4. BOCK SA. Prospective appraisal of complaints of adverse reactions to foods in children during the first three years of life. Pediatrics 1987: 79: 683-8.
5. SUOMALAINEIN H, LAINE S, SOPPI E, ISOLAURI E. Immunologic disturbances in cow's milk allergy II. Evidence for defective interferon-gamma generation. Pediatr Allergy Immunol 1992: 4: 203-7.
6. TANG M, KEMP A, VARIGOS G. IL-4 and interferon-gamma production in children with atopic disease. Clin Exp Immunol 1993: 92: 120-4.
7. TANG MLK, VARIGOS G, KEMP AS. Reduced interferon-gamma (IFN-gamma) secretion with increased IFN-gamma mRNA expression in atopic dermatitis: evidence for a post-transcriptional defect. Clin Exp Immunol 1994: 97: 483-90.
8. ÖSTERLUND P, JÄRVINEN K-M, LAINE S, SUOMALAINEN H. Defective tumour necrosis factor-α production in infants with cow's milk allergy. Pediatr Allergy Immunol 1999: 10: 186-90.
9. KLAUSNER RD, SAMUELSON LE. T cell antigen receptor activation pathways: The tyrosine kinase connection. Cell 1991: 64: 975-8.
10. WILKINSON M, MILLAR J. Control of the eukaryotic cell cycle by MAP kinase signaling pathways. FASEB J 2000: 14 (14): 2147-57.
11. ROBINSON MJ, COBB MH. Mitogen-activated protein kinase pathways. Curr Opin Cell Biol 1997: 9: 180-6.
12. BOCK SA, ATKINS FM. Patterns of food hypersensitivity during sixteen years of double-blind placebo-controlled food challenges. J Pediatr 1990: 117: 561-7.
13. SUOMALAINEN H, ISOLAURI E, KAILA M, VIRTANEN E, ARVILOMMI H. Cow's milk provocation induces an immune response to unrelated dietary antigens. Gut 1992: 33: 1179-83.
14. DIMON-GADAL S, RAYNAUD F, EVAIN-BRION D, KERYER G. MAP Kinase Abnormalities in Hyperproliferative Cultured Fibroblasts from Psoriatic Skin. J Invest Dermatol 1998: 110: 872-9.
15. OCKENFELS HM, NUSSBAUM G, SCHULTEWOLTER T, MERTINS K, WAGNER SN, GOOS M, Tyrosine Phosphorylation in Psoriatic T Cells Is Modulated by Drugs that Induce or Improve Psoriasis. Dermatology 1995: 191: 217-25.