MAP kinase abnormalities in hyperproliferative cultured fibroblasts from psoriatic skin

Journal of Investigative Dermatology

Volumn 110, Issue 6, 1998, Pages 872-879

  Dimon Gadal, S ^a   Raynaud, F ^a   Evain Brion, D ^a   Keryer, G ^a  

^a INSERM   (France)

Author keywords

Cyclic AMP dependent protein kinase; Mitogen activated protein kinases; Psoriasis

Indexed keywords

8 BROMO CYCLIC AMP; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATASE;

ARTICLE; CELL CULTURE; CELL PROLIFERATION; CELL SIZE; CELL STRUCTURE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME PURIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOCHEMISTRY; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PSORIASIS; SKIN CULTURE; SKIN FIBROBLAST;

EID: 0031837548     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.1998.00203.x     Document Type: Article

References (62)

1. N.G. Anderson J.L. Maller N.K. Tonks T.W. Sturgill Requirement of integration of signals from two distinct phosphorylation pathways for activation of MAP kinase Nature 343 1990 651 653
2. N. Basset-Seguin C. Escot J.P. Moles J.M. Blanchard C. Kerai J.J. Guihlou c-fos and c-jun proto-oncogene expression is decreased in psoriasis: an in situ quantitative analysis J Invest Dermatol 97 1991 672 678
3. T.A. Bird P.R. Sleath P.C. de Roos S.K. Dower G. Virca Interleukin-1 represents a new modality for the activation of extracellular signal-regulated kinases/ microtubule-associated protein-2 kinases J Biol Chem 266 1991 22661 22670
4. M.A. Bogoyevitch M.B. Andersson J. Gillespie-Brown A. Clerk P.E. Glennon S.J. Fuller P.H. Sugden Adrenergic receptor stimulation of the mitogen-activated protein kinases cascade and cardiac hypertrophy Biochem J 314 1996 115 121
5. P. Bohlen S. Stain W. Dairman S. Unfriend Fluorometric assay of proteins in nanogram range Arch Biochem Biophys 155 1973 213 220
6. A.L. Boynton J.F. Whietfield The role of cAMP in cell proliferation: a critical assessment of the evidence Adv Cyclic Nucleotide Res 15 1983 193 294
7. A. Brunet J.-M. Brondello G. L’Allemain P. Lenormand F. McKenzie G. Pagès J. Pouysségur Le module MAP kinase: rôle dans la prolifération cellulaire C R Soc Biol 189 1994 43 57
8. L. Buday J. Downward Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor Cell 73 1993 611 620
9. B.M.T. Burgering A.M.M. de Vries-Smits R.H. Medema P.C. van Weeren L.G.J. Tertoolen J.L. Bos Epidermal growth factor induces phosphorylation of extracellular signal-regulated kinase 2 via multiple pathways Mol Cell Biol 13 1993 7248 7256
10. B.M.T. Burgering G.J. Pronk P.C. Van Weeren P. Chardin J.L. Bos cAMP antagonizes p21ras-directed activation of extracellular signal-regulated kinase 2 and phosphorylation of mSos nucleotide exchange factor Embo J 12 1993 4211 4220
11. J.M. Carroll M.R. Romero F.M. Watt Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis Cell 83 1995 957 968
12. R.-H. Chen C. Sarnecki J. Blenis Nuclear localization and regulation of erk- and rsk-encoded protein kinases Mol Cell Biol 12 1992 915 927
13. S.J. Cook F. McCormick Inhibition by cAMP of Ras-dependent activation of Raf Science 262 1993 1069 1072
14. C.M. Crews A. Alessandrini R.L. Erikson The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product Science 258 1992 478 480
15. M.F. Dubois O. Bensaude MAP kinase activation during heat shock in quiescent and exponentially growing mammalian cells FEBS Lett 324 1993 191 196
16. J.T. Elder T. Chr Henseler E. istophers J.J. Voorhes R.P. Nair Of genes and antigens: the inheritance of psoriasis J Invest Dermatol 103 1994 150S 153S
17. L.R. Espinoza J.L. Aguilar C.G. Espinoza M.L. Cuéllar E. Scopelitis L.H. Silveira Fibroblast function in psoriatic arthritis. I. Alteration of cell kinetics and growth factor responses J Rheumatol 21 1994 1502 1506
18. D. Evain-Brion F. Raynaud A. Plet P. Laurent W.B. Anderson Deficiency of cyclic dependent protein kinases in human psoriasis Proc Natl Acad Sci USA 83 1986 5272 5276
19. T. Fredriksson U. Pettersson Severe psoriasis-oral therapy with a new retinoid: Dermatologica 157 1978 238 244
20. H. Gille M. Kortenjann O. Thomae C. Moomaw C. Slaughter M.H. Cobb P.E. Shaw ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation Embo J 14 1995 951 962
21. N. Gomez P. Cohen Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases Nature 353 1991 170 173
22. A.B. Gottlieb R.M. Grossman L. Khandke Studies of the effect of cyclosporine in psoriasis in vivo: combined effects on activated T lymphocytes and epidermal regenerative maturation J Invest Dermatol 98 1992 302 309
23. J.D. Graves J.S. Campbell E.G. Krebs Protein Serine/Threonine kinases of the MAPK cascade Ann NY Academ Sci 766 1995 320 343
24. L.A. Groom A.A. Sneddon D.R. Alessi S. Dowd S.M. Keyse Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase Embo J 15 1996 3621 3632
25. X.-F. Gu F. Raynaud D. Evain-Brion Increased chemotactic and mitogenic response of psoriatic fibroblasts to platelet-derived growth factor J Invest Dermatol 91 1988 599 602
26. P.W. Gunning G.E. Landreth M.A. Bothwell E.M. Shooter Differential and synergistic actions of nerve growth factor and cyclic AMP in PC12 cells J Cell Biol 89 1981 240 245
27. S. Hafner H.S. Adler H. Mischak Mechanism of inhibition of Raf-1 by protein kinase A Mol Cell Biol 14 1994 6696 6703
28. J.D. Han C.S. Rubin Regulation of cytoskeleton organization and paxillin dephosphorylation by cAMP. Studies on murine Y1 adrenal cells J Biol Chem 271 1996 29211 29215
29. P.L. Hordijk I. Verlaan K. Jalink E.J. van Corven W.H. Moolenaar cAMP abrogates the p21ras-mitogen-activated protein kinase pathway in fibroblasts J Biol Chem 269 1994 3534 3538
30. 2+ stimulates the activation of mitogen-activated protein kinase and cell growth in human fibroblasts Biochem J 310 1995 881 885
31. G.L. Johnson A.M. Gardner C. Lange-Carter N.X. Qian M. Russell S. Winitz How does the G protein, Gi2, transduce mitogenic signals? J Cell Biochem 54 1994 415 422
32. J.F. Krane D.P. Murphy A.B. Gottlieb M. Carter C.E. Hart J.G. Krueger Increased dermal expression of platelet-derived growth factor receptors in growth-activated skin wounds and psoriasis J Invest Dermatol 96 1991 983 986
33. G.G. Krueger C.M. Jorgensen Experimental models for psoriasis J Invest Dermatol 95 1990 56S 58S
34. R. Le Panse V. Mitev L.M. Houdebine B. Coulomb Protein kinase C-independent activation of mitogen-activated protein kinase by epidermal growth factor in skin fibroblasts Eur J Pharmacol 307 1996 339 345
35. S.J. Leevers H.F. Paterson C.J. Marshall Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane Nature 369 1994 411 414
36. mapkk) in fibroblasts J Cell Biol 122 1993 1079 1088
37. M. Lubinus K.E. Meier E.A. Smith K.C. Gause E.C. LeRoy M. Trojanowska Independent effects of platelet-derived growth factor isoforms on mitogen-activated protein kinase activation and mitogenesis in human dermal fibroblasts J Biol Chem 269 1994 9822 9825
38. F.R. McKenzie J. Pouysségur cAMP-mediated growth inhibition in fibroblasts is not mediated via mitogen-activated protein (MAP) kinase (ERK) inhibition J Biol Chem 271 1996 13476 13483
39. S.L. Pelech J.S. Sanghera Mitogen-activated protein kinases: versatile transducers for cell signaling Trends Biochem Science 17 1992 233 238
40. G.C. Priestley The fibroblast in psoriasis: master or slave? Euro J Dermatol 1 1991 185 191
41. G.C. Priestley L.W. Adams Hyperactivity of fibroblasts cultured from psoriatic skin. I. Faster proliferation and serum with-drawal Br J Dermatol 109 1983 157 164
42. L.B. Ray T.W. Sturgill Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 Proc Natl Acad Sci USA 84 1987 1502 1506 in vitro
43. F. Raynaud P. Gerbaud O. Enjolras I. Gorin M. Donnadieu W.B. Anderson D. Evain-Brion A cAMP abnormality in psoriasis Lancet i 1989 1153 1156
44. F. Raynaud P. Gerbaud X.F. Gu M. Donnadieu D. Evain-Brion Effect of retinoic acid on platelet-derived growth factor (PDGF) bioactivity and type-b PDGF receptors in normal and psoriatic human fibroblasts J Invest Dermatol 96 1991 111 115
45. F. Raynaud C. Leduc W.B. Anderson D. Evain-Brion Retinoid treatment of human psoriatic fibroblasts induces an increase in cyclic AMP dependent protein kinase activity J Invest Dermatol 89 1987 105 110
46. A.A. Reszka R. Seger C.D. Diltz E.G. Krebs E.H. Fischer Association of mitogen-activated protein kinase with microtubule cytoskeleton Proc Natl Acad Sci USA 92 1995 8881 8885
47. J.I. Sadoshima S. Izumo Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism Embo J 12 1993 1681 1692
48. P. Saiag B. Coulomb C. Lebreton E. Bell L. Dubertret Psoriatic fibroblasts induce hyperproliferation of normal keratinocytes in a skin equivalent model in vitro Science 230 1985 669 672
49. R. Seger E.G. Krebs The MAPK signaling cascade Faseb J 9 1995 726 735
50. R.R. Sevetson X. Kong J.C. Lawrence Increasing cAMP attenuates activation of mitogen-activated protein kinase Proc Natl Acad Sci USA 90 1993 10305 10309
51. V.S. Sivaraman H. Wang G.J. Nuovo C.C. Malbon Hyperexpression of mitogen-activated protein kinase in human breast cancer J Clin Invest 99 1997 1478 1483
52. P.H. Sugden A. Clerk Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptors Cell Signal 9 1997 337 351
53. H. Tamemoto T. Kadowaki K. Tobe Biphasic activation of two mitogen-activated protein kinases during the cell cycle in mammalian cells J Biol Chem 267 1992 20293 20297
54. D. Toullec P. Pianetti H. Coste The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C J Biol Chem 266 1991 15771 15781
55. S. Tournier P. Gerbaud W.B. Anderson S.M. Lohmann D. Evain-Brion F. Raynaud Post translational abnormality of the type II cyclic AMP-dependent protein kinase in psoriasis: Modulation by retinoic acid J Cell Biochem 57 1995 647 654
56. S. Trigon M. Morange Different carboxyl-domain kinase activities are induced by heat-shock and arsenite J Biol Chem 270 1995 13091 13098
57. H. Valdimarsson B.S. Baker I. Jonsdottir A. Powles L. Fry Psoriasis: a T-cell-mediated autoimmune disease induced by streptococcal superantigens? Immunol Today 16 1995 145 149
58. A.M. de Vries-Smits B.M. Burgering S.J. Leevers C.J. Marshall J.L. Bos Involvement of p21ras in activation of extracellular signal regulated kinase 2 Nature 357 1992 602 604
59. R.L. Whisler M.A. Goyette I.S. Grants Y.G. Newhouse Sublethal levels of oxidant stress stimulate multiple serine/threonine kinases and suppress protein phosphatases in Jurkat T cells Arch Biochem Biophys 319 1995 23 35
60. T. Wrone-Smith B.J. Nickoloff Dermal injection of immunocytes induces psoriasis J Clin Invest 98 1996 1878 1887
61. J. Wu P. Dent T. Jelinek A. Wolfman M.J. Weber T.W. Sturgill Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate Science 262 1993 1065 1072
62. S. Zolnierowicz B.A. Hemmings Protein phosphatases on the piste Trends Cell Biol 6 1996 359 362