Representation of umami taste in the human brain

Journal of Neurophysiology

Volumn 90, Issue 1, 2003, Pages 313-319

  De Araujo, I E T ^a,b   Kringelbach, M L ^a,b   Rolls, E T ^a,b   Hobden, P ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUTAMATE SODIUM; INOSINE PHOSPHATE; NUCLEOTIDE;

ARTICLE; BLOOD OXYGENATION; BRAIN CORTEX; BRAIN DEPTH STIMULATION; BRAIN FUNCTION; BRAIN REGION; CINGULATE GYRUS; CONTROLLED STUDY; EVOKED CORTICAL RESPONSE; FEMALE; HUMAN; HUMAN EXPERIMENT; INSULA; MACACA; MALE; NERVE CELL; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; ORBITAL CORTEX; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STIMULUS; TASTE ACUITY; TASTE DISCRIMINATION;

EID: 0038500846     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00669.2002     Document Type: Article

References (39)

1. Baylis LL and Rolls ET. Responses of neurons in the primate taste cortex to glutamate. Physiol Behav 49: 973-979, 1991.
2. Baylis LL, Rolls ET, and Baylis GC. Afferent connections of the orbitofrontal cortex taste area of the primate. Neuroscience 64: 801-812, 1994.
3. Bush G, Luu P, and Posner MI. Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 4: 215-222, 2000.
4. Cardinal RN, Parkinson JA, Hall J, and Everitt BJ. Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex. Neurosci Biobehav Rev 26: 321-352, 2002.
5. Chaudhari N, Landin AM, and Roper SD. A metabotropic glutamate receptor variant functions as a taste receptor. Nature Neurosci 3: 113-119, 2000.
6. Childress AR, Mozley PD, McElgin W, Fitzgerald J, Reivich M, and O'Brien CP. Limbic activation during cue-induced cocaine craving. Am J Psychiatry 156: 11-18, 1999.
7. Collins D, Neelin P, Peters T, and Evans AC. Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. J Comp Ass Tomogr 18: 192-205, 1994.
8. Craig AD. Opinion: how do you feel? Interoception: the sense of the physiological condition of the body. Nat Rev Neurosci 3: 655-666, 2002.
9. Davidson RJ. Anterior cerebral asymmetry and the nature of emotion. Brain Cogn 6: 245-268, 1992.
10. de Araujo IET, Kringelbach ML, and Rolls ET. Different areas of the human orbitofrontal and cingulate cortex activated by pleasant and unpleasant odors. Soc Neurosci Abstr 517.1, 2002.
11. Devinsky O, Morrell MJ, and Vogt BA. Contributions of anterior cingulate cortex to behaviour. Brain 118: 279-306, 1995.
12. Drevets WC, Price JL, Simpson JR, Jr, Todd RD, Reich T, Vannier M, and Raichle ME. Subgenual prefrontal cortex abnormalities in mood disorders. Nature 386: 824-827, 1997.
13. Friston KJ, Holmes AP, Price CJ, Buchel C, and Worsley KJ. Multisubject fMRI studies and conjunction analyses. Neuroimage 10: 385-396, 1999.
14. Hyder F, Rothman DL, and Shulman RG. Total neuroenergetics support localized brain activity: implications for the interpretation of fMRI. Proc Natl Acad Sci USA 99: 10771-10776, 2002.
15. Kawamura Y and Kare M. Umami: A Basic Taste. New York: Marcel Dekker, 1987.
16. Lin W and Kinnamon SC. Responses to monosodium glutamate and guanosine 5′-monophosphate in rat fungiform taste cells. Ann N Y Acad Sci 855: 407-411, 1998.
17. Logothetis NK, Pauls J, Augath M, Trinath T, and Oeltermann A. Neurophysiological investigation of the basis of the fMRI signal. Nature 412: 150-157, 2001.
18. Ninomiya Y and Funakoshi M. Qualitative discrimination among 'umami' and the four basic taste substances in mice. In: Umami: A Basic Taste, edited by Kare M. New York: Dekker, 1987, p. 365-385.
19. O'Doherty J, Kringelbach ML, Rolls ET, Hornak J, and Andrews C. Abstract reward and punishment representations in the human orbitofrontal cortex. Nat Neurosci 4: 95-102, 2001a.
20. O'Doherty J, Rolls ET, Francis S, Bowtell R, and McGlone F. Representation of pleasant and aversive taste in the human brain. J Neurophysiol 85: 1315-1321, 2001b.
21. Pritchard TC, Macaluso DA, and Eslinger PJ. Taste perception in patients with insular cortex lesions. Behav Neurosci 113: 663-671, 1999.
22. Rifkin B and Bartoshuk LM. Taste synergism between monosodium glutamate and disodium 5′-guanylate. Physiol Behav 24: 1169-1172, 1980.
23. Rolls ET. The Brain and Emotion. Oxford: Oxford, 1999.
24. Rolls ET. The representation of umami taste in the taste cortex. J Nutr S960-S965, 2000.
25. Rolls ET, Critchley H, Wakeman EA, and Mason R. Responses of neurons in the primate taste cortex to the glutamate ion and to inosine 5′-monophosphate. Physiol Behav 59: 991-1000, 1996.
26. Rolls ET, O'Doherty J, Kringelbach ML, Francis S, Bowtell R, and McGlone F. Pleasant and painful touch are represented in the human orbitofrontal and cingulate cortices. Cereb Cortex 13: 308-317, 2003.
27. Rolls ET, Sienkiewicz ZJ, and Yaxley S. Hunger modulates the responses to gustatory stimuli of single neurons in the caudolateral orbitofrontal cortex of the macaque monkey. Eur J Neurosci 1: 53-60, 1989.
28. Rolls ET, Yaxley S, and Sienkiewicz ZJ. Gustatory responses of single neurons in the caudolateral orbitofrontal cortex of the macaque monkey. J Neurophysiol 64: 1055-1066, 1990.
29. Small DM, Zald DH, Jones Gotman M, Zatorre RJ, Pardo JV, Frey S, and Petrides M. Human cortical gustatory areas: a review of functional neuroimaging data. Neuroreport 10: 7-14, 1999.
30. Smith AJ, Blumenfeld H, Behar KL, Rothman DL, Shulman RG, and Hyder F. Cerebral energetics and spiking frequency: the neurophysiological basis of fMRI. Proc Natl Acad Sci USA 99: 10765-10770, 2002.
31. Wilson J, Jenkinson M, de Araujo IET, Kringelbach ML, Rolls ET, and Jezzard P. Fast, fully automated global and local magnetic field optimization for fMRI of the human brain. Neuroimage 17: 967-976, 2002.
32. Worsley KJ, Marrett P, Neelin AC, Friston KJ, and Evans AC. A unified statistical approach for determining significant signals in images of cerebral activation. Hum Brain Mapp 4: 58-73, 1996.
33. Yamaguchi S. The synergistic taste effect of monosodium glutamate and disodium 5′-inosinate. J Food Sci 32: 473-478, 1967.
34. Yamaguchi S and Kimizuka A. Psychometric studies on the taste of monosodium glutamate. In: Glutamic Acid: Advances in Biochemistry and Physiology, edited by Wurtman R. New York: Raven, 1979, p. 35-54.
35. Yamaguchi S and Ninomiya K. Umami and food palatability. J Nutr 130: 921S-926S, 2000.
36. Yaxley S, Rolls, ET, and Sienkiewicz ZJ. Gustatory responses of single neurons in the insula of the macaque monkey. J Neurophysiol 63: 689-700, 1990.
37. Yoshida M and Saito S. Multidimensional scaling of the taste of amino acids. Jap Psychol Res 11: 149-166, 1969.
38. Zald DH and Pardo JV. Emotion, olfaction, and the human amygdala: amygdala activation during aversive olfactory stimulation. Proc Natl Acad Sci USA 94: 4119-4124, 1997.
39. Zatorre RJ, Jones-Gotman M, Evans AC,and Meyer E. Functional localization and lateralization of human olfactory cortex. Nature 360: 339-340, 1992.