Protocol for the production of concentrated extracts of food folate for use in human bioavailability studies

Journal of Agricultural and Food Chemistry

Volumn 51, Issue 15, 2003, Pages 4382-4388

  McKillop, Derek J ^a   Pentieva, Kristina D ^a   Scott, John M ^b   Strain, J J ^a   McCreedy, Richard ^c   Alexander, Joy ^c   Patterson, Karen ^c   Hughes, Joan ^a   McNulty, Helene ^a  

^a UNIVERSITY OF ULSTER   (United Kingdom)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c Loughry College   (United Kingdom)

Author keywords

Bioavailability; Food folate; Monoglutamate; Polyglutamate

Indexed keywords

FOLIC ACID; FOLIC ACID DERIVATIVE; PTEROPTIN;

ARTICLE; BIOAVAILABILITY; DIET; EGG; EXTRACTION; FOOD COMPOSITION; FOOD INTAKE; FOOD PROCESSING; LABORATORY; METHODOLOGY; PH; SAFETY; SPINACH; THERMAL ANALYSIS; YEAST;

BIOLOGICAL AVAILABILITY; EGG YOLK; FOLIC ACID; FOOD ANALYSIS; FOOD MICROBIOLOGY; HEAT; HUMANS; HYDROGEN-ION CONCENTRATION; SACCHAROMYCES CEREVISIAE; SPINACIA OLERACEA;

SPINACIA OLERACEA;

EID: 0038492784     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf0262312     Document Type: Article

References (39)

1. Medical Research Council Vitamin Study Research Group. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 1991, 338, 131-137.
2. Czeizel, A. E.; Dudas, I. Prevention of first occurrence of neural tube defects by periconceptional vitamin supplementation. N. Engl. J. Med. 1992, 327, 1832-1835.
3. Boushey, C. J.; Beresford, S. A. A.; Omenn, G. S.; Motulsky, A. G. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: probable benefits of increasing folic acid intakes. JAMA-J. Am. Med Assoc. 1995, 274, 1049-1057.
4. Choi, S. W.; Mason, J. B. Folate and Carcinogenesis: An integrated scheme. J. Nutr. 2000, 130, 129-132.
5. Kim, Y. I.; Pogribny, I. P.; Basnakian, A. G.; Miller, J. W.; Selhub, J.; James, S. J.; Mason, J. B. Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppresser gene. Am. J. Clin. Nutr. 1997, 65, 46-52.
6. Jacob, R. A.; Gretz, D. M.; Taylor, P. C.; James, S. J.; Pogribny, I. P.; Miller, B. J.; Henning, S.; Sendseid, M. E. Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women. J. Nutr. 1998, 128, 1204-1212.
7. Branda, R. F.; Blickensderfer, D. B. Folate deficiency increases genetic damage caused by alkylating agents in γ-irradiation in Chinese hamster ovary cells. Cancer Res. 1993, 53, 5401-5408.
8. Department of Health. Folic Acid and the Prevention of Neural Tube Defects; Report from an Expert Advisory Group; Her Majesty's Stationary Office: London, U.K., 1992.
9. Public Health Service. Centers for Disease Control and Prevention. Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. MMWR Morbid. Mortal Wkly. Rep. 1992, 41, 1-7.
10. National Health and Medical Research Council. Revised Statement on the Relationship between Dietary Folic Acid and Neural Tube Defects Such as Spina Bifida, 115th session; NHMRC: Melbourne, Australia, 1993.
11. Food and Drug Administration. Food standards: amendment of standards of identity for enriched grain products to require addition of folic acid. Fed. Regist. 1996, 61, 8781-8789.
12. Savage, D. G.; Lindenbaum, J. Folate-Cobalamin interactions. In Folate in Health and Disease; Bailey, L. B., Ed.; Dekker: New York, 1995; pp 237-285.
13. Cuskelly, G. J.; McNulty, H.; Scott, J. M. Effect of increasing dietary folate on red-cell folate: Implications for prevention of neural tube defects. Lancet 1996, 347. 657-659.
14. Oakley, G. P. Eat right and take a multivitamin. N. Engl. J. Med. 1998, 338, 1060-1061.
15. Koebnick, C.; Heins, U. A.; Hoffmann, I.; Dangnelie P. C.; Leitzmann, C. Folate status during pregnancy in women is improved by long-term high vegetable intake compared with the average Western diet. J. Nutr. 2001, 131, 733-739.
16. Sauberlich, H. E.; Kretsch, M. J.; Skala, J. H.; Johnson, H. L.; Taylor, P. C. Folate requirement and metabolism in nonpregnant wemen. Am. J. Clin. Nutr. 1987, 46, 1016-1028.
17. Gregory, J. F. Case study: Folate bioavailability. J. Nutr. 2001, 131, 1376S-1382S.
18. Gärtner, C.; Stahl, W.; Sies, H. Lycopene is more bioavailable from tomato paste than from fresh tomatoes. Am. J. Clin. Nutr. 1997, 66, 116-122.
19. McKillop, D.; Pentieva, K.; Daly, D.; McPartlin, J. M.; Hughes, J.; Strain, J. J.; Scott, J. M.; McNulty, H. The effect of different cooking methods on folate retention in various foods which are amongst the major contributors to folate intake in the UK diet. Br. J. Nutr. 2002, 88, 681-688.
20. Tamura, T. Determination of food folate. J. Nutr. Biochem. 1998, 9, 285-293.
21. Tamura, T.; Mizuno, Y.; Johnston, K. E.; Jacob, R. A. Food folate assay with protease, α-amylase, and folate conjugase treatments. J. Agric. Food Chem. 1997, 45, 135-139.
22. Witthöft, C. M.; Forssén, K.; Johannesson. L.; Jägerstad, M. Folates-food sources, analyses, retention and bioavailability. Scand. J. Nutr./Naringsforskning 1999, 43, 138-146.
23. Pfeiffer, C. M.; Rogers, L. M.; Gregory, J. F. Determination of folate in cereal-grain food products using trienzyme extraction and combined affinity and reversed-phase liquid chromatography. J. Agric. Food Chem. 1997, 45, 407-413.
24. Beltz, S.; Nau H. Determination of folate patterns in mouse plasma, erythrocytes, and embryos by HPLC coupled with a microbiological assay. Anal. Biochem. 1998, 265, 157-166.
25. Molloy, A. M.; Scott, J. M. Microbiological assay for serum, plasma and red cell folate using cryopreserved, microtiter plate method. Methods Enzymol. 1997, 281, 43-53.
26. IFST. Guidelines for developments and use of microbiological criteria for foods. Food Sci. Technol. Today 1997, 11 (3), 56-62.
27. Gregory, J. F. Determination of folacins in foods and other biological materials. J. Assoc. Off. Anal. Chem. 1984, 67, 1015-1019.
28. Gregory, J. F. Chemicals and nutritional aspects of folate research: Analytical procedures, methods of folate synthesis, stability and bioavailability of dietary folates. In. Advances in Food and Nutrition Research; Kinsella, E., Ed.; Academic Press: New York, 1989; Vol. 33, pp 1-101.
29. Vahteristo, L. T.; Ollilainen, V.; Varo, P. Liquid chromatographic determination of folate monoglutamates in fish, meat, egg, and dairy products consumed in Finland. J. Assoc. Off. Anal. Chem. 1997, 80, 373-378.
30. Seyoum, E.; Selhub, J. Combined affinity and ion pair column chromatographies for the analysis of food folate. J. Nutr. Biochem. 1993, 4, 488-494.
31. Konings, E. J. M.; Roomans, H. H. S.; Dorant, E.; Goldbohm, R. A.; Saris, W. H. M.; Van den Brandt, P. A. Folate intake of the Dutch population according to newly established liquid chromatography data for foods. Am. J. Clin. Nutr. 2001, 73, 765-776.
32. Chen, T.; Song, Y.; Kirsch, A. J. Effect of blanching, freezing and storage on folacin content of spinach. Nutr. Rep. Int. 1983, 28, 317-324.
33. Tamura, T.; Shin, Y. S.; Williams, M. A.; Stokstad, E. L. R. Lactobacillus casei response to pteroylpolyglutamates. Anal. Biochem. 1972, 49, 517-521.
34. Ndaw, S.; Bergaentzlé, M.; Aoudé-Werner, D.; Lahély, S.; Hasselmann, C. Determination of folates in foods by high-performance liquid chromatography with fluorescence detection after precolumn conversion to 5-methyltetrahydrofolates. J. Chromatogr. A 2001, 928, 77-90.
35. Müller, H. Bestimmung der folsäure-Gehalte von Gemüse und Obst mit Hilfe der Hochleistungsflüssigchromatographie (HPLC). Z. Lebensm. Unters. Forsch. 1993, 196, 137-141.
36. Vahteristo, L. T.; Lehikoinen, K.; Ollilainen, V.; Varo, P. Application of an HPLC assay for the determination of folate derivatives in some vegetables, fruits and berries consumed in Finland. Food Chem. 1997, 59, 589-597.
37. McNulty, H.; Hannon-Fletcher, M. P. A.; Armstrong, N. C.; Pentieva, K.; Ward, M.; McKillop, D. J.; Strain, J. J.; McCreedy, R.; Alexander, J.; Patterson, K.; Scott, J. M. A controlled intervention study to determine the bioavailability of natural folates extracted from the food matrix. J. Nutr. 2003, submitted for publication.
38. Hannon-Fletcher, M. P. A.; Armstrong, N. C.; Scott, J. M.; Ward, M.; Strain, J. J.; Pentieva, K.; Dunn, A.; Molloy, A. M.; Scullion, M.; McNulty, H. Bioavailability of food folates in a controlled intervention study. Proc. Nutr. Soc. 2003, in press.
39. Wei, M. M.; Bailey, L. B.; Toth, J. P.; Gregory, J. F. Bioavailability for humans of deuterium-labeled monoglutamyl and polyglutamyl folates is affected by selected foods. J. Nutr. 1996, 126, 3100-3108.