Improved packaging system for generation of high-level noncytotoxic HSV-1 amplicon vectors using Cre-loxP site-specific recombination to delete the packaging signals of defective helper genomes

Human Gene Therapy

Volumn 14, Issue 11, 2003, Pages 1049-1063

  Zaupa, Cécile ^a   Revol Guyot, Valerie ^a   Epstein, Alberto L ^a  

^a CENTRE DE GÉNÉTIQUE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; GENE PRODUCT; ICP34.5 PROTEIN; ICP4 PROTEIN; UNCLASSIFIED DRUG; VIRUS VECTOR;

AMPLICON; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA PACKAGING; DNA RECOMBINATION; DNA TRANSFER; GENE DELETION; GENE LOCUS; GENE THERAPY; HELPER VIRUS; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; NONHUMAN; VIRUS RECOMBINANT;

ANIMALS; CELL LINE; COSMIDS; DEFECTIVE VIRUSES; FLOW CYTOMETRY; GENE THERAPY; GENETIC VECTORS; GENOME, VIRAL; HELPER VIRUSES; HERPESVIRUS 1, HUMAN; HUMANS; IMMEDIATE-EARLY PROTEINS; INTEGRASES; OPEN READING FRAMES; RECOMBINATION, GENETIC; SEQUENCE DELETION; TRANSGENES; VIRAL PROTEINS; VIRUS ASSEMBLY;

ANIMALIA; DNA VIRUSES; HUMAN HERPESVIRUS 1; SIMPLEXVIRUS;

EID: 0038488560     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/104303403322124774     Document Type: Article

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