Intracellular Cre-mediated deletion of the unique packaging signal carried by a herpes simplex virus type 1 recombinant and its relationship to the cleavage-packaging process

Journal of Virology

Volumn 74, Issue 18, 2000, Pages 8402-8412

  Logvinoff, C ^a   Epstein, A L ^a  

^a CENTRE DE GÉNÉTIQUE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA;

ARTICLE; DNA CLEAVAGE; DNA DETERMINATION; DNA PACKAGING; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; VIRUS RECOMBINANT; VIRUS REPLICATION;

ANIMALS; CAPSID; CELL LINE; CERCOPITHECUS AETHIOPS; ELECTROPHORESIS, GEL, PULSED-FIELD; GENOME, VIRAL; HERPESVIRUS 1, HUMAN; INTEGRASES; MICROSCOPY, ELECTRON; RECOMBINATION, GENETIC; SEQUENCE DELETION; VERO CELLS; VIRAL PROTEINS; VIRUS ASSEMBLY;

EID: 0033851097     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.18.8402-8412.2000     Document Type: Article

References (36)

1. Herpes simplex virus replicative concatemers contain L components in inverted orientation
2. Equimolar generation of the four possible arrangements of adjacent L components in herpes simplex virus type 1 replicative intermediates
3. Cloning, sequencing, and functional characterization of the two sub-units of the pseudorabies virus DNA polymerase holoenzyme: Evidence for the specificity of interaction
4. A cosmid-based system for constructing mutants of herpes simplex virus type 1
5. The herpes simplex virus amplicon: Cleavage of concatemeric DNA is linked to packaging and involves amplification of the terminally reiterated a sequence
6. Functional domains within the a sequence involved in the cleavage-packaging of herpes simplex virus DNA
7. Mutations in herpes simplex virus type 1 genes encoding VP5 and VP23 abrogate capsid formation and cleavage of replicated DNA
8. Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells
9. The protease of herpes simplex virus type 1 is essential for functional capsid formation and viral growth
10. Proteins specified by herpes simplex virus. VIII. Characterization and composition of multiple capsid forms of subtypes 1 and 2
11. A new technique for the assay of infectivity of human adenovirus DNA
12. Asymmetric DNA bending in the Cre-loxP site-specific recombination synapse
13. Capsid assembly and DNA packaging in herpes simplex virus
14. Genetic engineering of herpes simplex virus and vector genomes carrying loxP sites in cells expressing Cre recombinase
15. The a sequence is dispensable for isomerization of the herpes simplex virus type 1 genome
16. The product of the herpes simplex virus type 1 UL25 gene is required for encapsidation but not for cleavage of replicated viral DNA
17. The ends on herpesvirus DNA replicative concatemers contain pac2 cis cleavage/packaging elements and their formation is controlled by terminal cis sequences
18. Site-specific inversion of the herpes simplex virus genome: Domain and structural features
19. Structure and role of the herpes simplex virus DNA termini in inversion, circularization and generation of virion DNA
20. Herpes-virus dependent amplification and inversion of cell-associated viral thymidine kinase gene flanked by viral a sequences and linked to an origin of viral DNA replication
21. The cleavage recognition signal is contained within the sequences surrounding an a-a junction in herpes simplex virus DNA
22. Assembly of the herpes simplex virus capsid: Characterization of intermediates observed during cell-free capsid formation
23. Isolation of herpes simplex virus procapsids from cells infected with a protease-deficient mutant virus
24. A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal
25. A noninverting genome of a viable herpes simplex virus 1: Presence of head-to-tail linkages in packaged genomes and requirements for circularization after infection
26. Characterization of the UL33 gene product of herpes simplex virus 1
27. A non-cytotoxic herpes simplex virus vector which expresses Cre recombinase directs efficient site specific recombination
28. Packaging-competent capsids of a herpes simplex virus temperature-sensitive mutant have properties similar to those of in vitro-assembled procapsids
29. Proteolytic cleavage of the amino terminus of the U(L)15 gene product of herpes simplex virus type 1 is coupled with maturation of viral DNA into unit-length genomes
30. Requirement for double-strand breaks but not for specific DNA sequences in herpes simplex virus type 1 genome isomerization events
31. Study of the structure of replicative intermediates of HSV-1 DNA by pulsed-field electrophoresis
32. The herpes simplex virus amplicon: A new eucaryotic defective-virus cloning-amplifying vector
33. Signals for site-specific cleavage of HSV DNA: Maturation involves two separate cleavage events at sites distal to the recognition sequences
34. Site-specific cleavage/packaging of herpes simplex virus DNA and the selective maturation of nucleocapsids containing full length viral DNA
35. Directed repeats of the herpes simplex virus a sequence promote nonconservative homologous recombination that is not dependent on XPF/ERCC4
36. Herpes simplex virus type 1 cleavage and packaging proteins UL15 and UL28 are associated with B but not C capsids during packaging