-
1
-
-
0034649696
-
Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia
-
Rai KR, Peterson BL, Kolitz J, et al: Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia. N Engl J Med 343:1750-1757, 2000
-
(2000)
N Engl J Med
, vol.343
, pp. 1750-1757
-
-
Rai, K.R.1
Peterson, B.L.2
Kolitz, J.3
-
2
-
-
0028945716
-
2-Chlorodeoxyadenosine activity in patients with untreated chronic lymphocytic leukemia
-
Saven A, Lemon RH, Kosty M, et al: 2-Chlorodeoxyadenosine activity in patients with untreated chronic lymphocytic leukemia. J Clin Oncol 13:570-574, 1995
-
(1995)
J Clin Oncol
, vol.13
, pp. 570-574
-
-
Saven, A.1
Lemon, R.H.2
Kosty, M.3
-
3
-
-
0024551346
-
Pentostatin in chronic lymphocytic leukemia: A phase II trial of Cancer and Leukemia Group B
-
Dillman RO, Mick R, McIntyre OR: Pentostatin in chronic lymphocytic leukemia: A phase II trial of Cancer and Leukemia Group B. J Clin Oncol 7:433-438, 1989
-
(1989)
J Clin Oncol
, vol.7
, pp. 433-438
-
-
Dillman, R.O.1
Mick, R.2
McIntyre, O.R.3
-
4
-
-
0001003335
-
The Croonian Lecture: On immunity with special reference to cell life
-
Ehrlich P: The Croonian Lecture: "On immunity with special reference to cell life." Proc R Soc 66:424-448, 1900
-
(1900)
Proc R Soc
, vol.66
, pp. 424-448
-
-
Ehrlich, P.1
-
5
-
-
0034523170
-
Update on the biology of chronic lymphocytic leukemia
-
Bannerji R, Byrd JC: Update on the biology of chronic lymphocytic leukemia. Curr Opin Oncol 12:22-29, 2000
-
(2000)
Curr Opin Oncol
, vol.12
, pp. 22-29
-
-
Bannerji, R.1
Byrd, J.C.2
-
6
-
-
0033567968
-
Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
-
Damle RN, Wasil T, Fais F, et al: Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood 94:1840-1847, 1999
-
(1999)
Blood
, vol.94
, pp. 1840-1847
-
-
Damle, R.N.1
Wasil, T.2
Fais, F.3
-
7
-
-
0021176984
-
Therapy of chronic lymphocytic leukemia and cutaneous T-cell lymphoma with T101 monoclonal antibody
-
Dillman RO, Shawler DL, Dillman JB, et al: Therapy of chronic lymphocytic leukemia and cutaneous T-cell lymphoma with T101 monoclonal antibody. J Clin Oncol 2:881-891, 1984
-
(1984)
J Clin Oncol
, vol.2
, pp. 881-891
-
-
Dillman, R.O.1
Shawler, D.L.2
Dillman, J.B.3
-
8
-
-
0023848068
-
A phase I study of T101-ricin A chain immunotoxin in refractory chronic lymphocytic leukemia
-
Hertler AA, Schlossman DM, Borowitz MJ, et al: A phase I study of T101-ricin A chain immunotoxin in refractory chronic lymphocytic leukemia. J Biol Response Mod 7:97-113, 1988
-
(1988)
J Biol Response Mod
, vol.7
, pp. 97-113
-
-
Hertler, A.A.1
Schlossman, D.M.2
Borowitz, M.J.3
-
9
-
-
0345683032
-
Pharmacokinetics of 1-131 T101 monoclonal antibody in patients with chronic lymphocytic leukemia
-
Zimmer AM, Kaplan EH, Kazikiewicz JM, et al: Pharmacokinetics of 1-131 T101 monoclonal antibody in patients with chronic lymphocytic leukemia. Antibody Immunoconjugates Radiopharm 1:291-303, 1988
-
(1988)
Antibody Immunoconjugates Radiopharm
, vol.1
, pp. 291-303
-
-
Zimmer, A.M.1
Kaplan, E.H.2
Kazikiewicz, J.M.3
-
10
-
-
0022446137
-
Effects of therapy with T101 ricin A-chain immunotoxin in two leukemia patients
-
Laurent G, Pris J, Parcel J-P, et al: Effects of therapy with T101 ricin A-chain immunotoxin in two leukemia patients. Blood 67:1680-1687, 1986
-
(1986)
Blood
, vol.67
, pp. 1680-1687
-
-
Laurent, G.1
Pris, J.2
Parcel, J.-P.3
-
11
-
-
0021922296
-
Treatment of chronic lymphocytic leukaemia with monoclonal anti-idiotype antibody
-
Capel PJA, Preijers FWMB, Allebes WA, et al: Treatment of chronic lymphocytic leukaemia with monoclonal anti-idiotype antibody. Neth J Med 28:112-118, 1985
-
(1985)
Neth J Med
, vol.28
, pp. 112-118
-
-
Capel, P.J.A.1
Preijers, F.W.M.B.2
Allebes, W.A.3
-
12
-
-
0025203831
-
Shared idiotype expression by chronic lymphocytic leukemia and B-cell lymphoma
-
Chatterjee M, Barcos M, Han T, et al: Shared idiotype expression by chronic lymphocytic leukemia and B-cell lymphoma. Blood 76:1825-1829, 1990
-
(1990)
Blood
, vol.76
, pp. 1825-1829
-
-
Chatterjee, M.1
Barcos, M.2
Han, T.3
-
13
-
-
0025870519
-
Expression of shared idiotypes in chronic lymphocytic leukemia and small lymphocytic lymphoma
-
Swisher EM, Shawler DL, Collins HA, et al: Expression of shared idiotypes in chronic lymphocytic leukemia and small lymphocytic lymphoma. Blood 77:1977-1982, 1991
-
(1991)
Blood
, vol.77
, pp. 1977-1982
-
-
Swisher, E.M.1
Shawler, D.L.2
Collins, H.A.3
-
14
-
-
0023717079
-
The development of non-responsiveness to immunotherapy with monoclonal anti-idiotypic antibodies in a patient with B-CLL
-
Allebes WA, Preijers FWMB, Haanen C, et al: The development of non-responsiveness to immunotherapy with monoclonal anti-idiotypic antibodies in a patient with B-CLL. Br J Haematol 70:295-300, 1988
-
(1988)
Br J Haematol
, vol.70
, pp. 295-300
-
-
Allebes, W.A.1
Preijers, F.W.M.B.2
Haanen, C.3
-
15
-
-
0024566393
-
Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: Influence of antibody isotype
-
Dyer MJS, Hale G, Hayhoe FGJ, et al: Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: Influence of antibody isotype. Blood 73:1431-1439, 1989
-
(1989)
Blood
, vol.73
, pp. 1431-1439
-
-
Dyer, M.J.S.1
Hale, G.2
Hayhoe, F.G.J.3
-
17
-
-
0032005642
-
Levels of expression of CD52 in normal and leukemic B and T cells: Correlation with in vivo therapeutic responses to CAMPATH-1H
-
Ginaldi L, De martinis M, Matutes E, et al: Levels of expression of CD52 in normal and leukemic B and T cells: Correlation with in vivo therapeutic responses to CAMPATH-1H. Leuk Res 22:185-191, 1998
-
(1998)
Leuk Res
, vol.22
, pp. 185-191
-
-
Ginaldi, L.1
De martinis, M.2
Matutes, E.3
-
18
-
-
0030897222
-
Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia
-
Österborg A, Dyer MJS, Bunjes D, et al: Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. J Clin Oncol 15:1567-1574, 1997
-
(1997)
J Clin Oncol
, vol.15
, pp. 1567-1574
-
-
Österborg, A.1
Dyer, M.J.S.2
Bunjes, D.3
-
19
-
-
0037092951
-
Therapeutic role of alemtuzumab (CAMPATH-1H) in patients who have failed fludarabine: Results of a large international study
-
Keating MJ, Flinn I, Jain V, et al: Therapeutic role of alemtuzumab (CAMPATH-1H) in patients who have failed fludarabine: Results of a large international study. Blood 99:3554-3561, 2002
-
(2002)
Blood
, vol.99
, pp. 3554-3561
-
-
Keating, M.J.1
Flinn, I.2
Jain, V.3
-
20
-
-
0031027623
-
Subcutaneous CAMPATH-1H in fludarabine-resistant/relapsed chronic lymphocytic and B-prolymphocytic leukaemia
-
Bowen AL, Zomas A, Emmett E, et al: Subcutaneous CAMPATH-1H in fludarabine-resistant/relapsed chronic lymphocytic and B-prolymphocytic leukaemia. Br J Haematol 96:617-619, 1997
-
(1997)
Br J Haematol
, vol.96
, pp. 617-619
-
-
Bowen, A.L.1
Zomas, A.2
Emmett, E.3
-
21
-
-
0000338685
-
CAMPATH1H therapy for patients with refractory chronic lymphocytic leukemia (CLL)
-
abstr 2356
-
Rawstron AC, Davies FE, Evans P, et al: CAMPATH1H therapy for patients with refractory chronic lymphocytic leukemia (CLL). Blood 90:529a, 1997 (abstr 2356)
-
(1997)
Blood
, vol.90
-
-
Rawstron, A.C.1
Davies, F.E.2
Evans, P.3
-
22
-
-
0009351039
-
Campath-1H in refractory B-CLL: Complete remission despite p53 gene mutation
-
abstr 3211
-
Stilgenbauer S, Scherer K, Kröber A, et al: Campath-1H in refractory B-CLL: Complete remission despite p53 gene mutation. Blood 98:771, 2001 (abstr 3211)
-
(2001)
Blood
, vol.98
, pp. 771
-
-
Stilgenbauer, S.1
Scherer, K.2
Kröber, A.3
-
23
-
-
0036242664
-
Alemtuzumab in relapsed or refractory chronic lymphocytic leukemia and prolymphocytic leukemia
-
McCune SL, Gockerman JP, Moore JO, et al: Alemtuzumab in relapsed or refractory chronic lymphocytic leukemia and prolymphocytic leukemia. Leuk Lymphoma 43:1007-1011, 2002
-
(2002)
Leuk Lymphoma
, vol.43
, pp. 1007-1011
-
-
McCune, S.L.1
Gockerman, J.P.2
Moore, J.O.3
-
24
-
-
0029937765
-
Humanized CD52 monoclonal antibody Campath-1H as first-line treatment in chronic lymphocytic leukaemia
-
Österborg A, Passas AS, Anagnostopoulos A, et al: Humanized CD52 monoclonal antibody Campath-1H as first-line treatment in chronic lymphocytic leukaemia. Br J Haematol 93:151-153, 1996
-
(1996)
Br J Haematol
, vol.93
, pp. 151-153
-
-
Österborg, A.1
Passas, A.S.2
Anagnostopoulos, A.3
-
25
-
-
0036683449
-
Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (CAMPATH-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL)
-
Lundin J, Kimby E, Björkholm M, et al: Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (CAMPATH-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL). Blood 100:768-773, 2002
-
(2002)
Blood
, vol.100
, pp. 768-773
-
-
Lundin, J.1
Kimby, E.2
Björkholm, M.3
-
26
-
-
0038315030
-
Patients with refractory B-CLL and T-PLL treated with alemtuzumab (Campath) on a compassionate basis. A report on efficacy and safety of CAM511 trial
-
abstr 3165
-
Rai KR, Keating MJ, Coutré S, et al: Patients with refractory B-CLL and T-PLL treated with alemtuzumab (Campath) on a compassionate basis. A report on efficacy and safety of CAM511 trial. Blood 100:802a, 2002 (abstr 3165)
-
(2002)
Blood
, vol.100
-
-
Rai, K.R.1
Keating, M.J.2
Coutré, S.3
-
27
-
-
0028987180
-
p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias
-
Döhner H, Fischer K, Bentz M, et al: p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias. Blood 85:1580-1589, 1995
-
(1995)
Blood
, vol.85
, pp. 1580-1589
-
-
Döhner, H.1
Fischer, K.2
Bentz, M.3
-
28
-
-
0030812012
-
Treatment of T-cell prolymphocytic leukemia with human CD52 antibody
-
Pawson R, Dyer MJS, Barge R, et al: Treatment of T-cell prolymphocytic leukemia with human CD52 antibody. J Clin Oncol 15:2667-2672, 1997
-
(1997)
J Clin Oncol
, vol.15
, pp. 2667-2672
-
-
Pawson, R.1
Dyer, M.J.S.2
Barge, R.3
-
29
-
-
0035885965
-
High remission rate in T-cell prolymphocytic leukemia with CAMPATH-1H
-
Dearden CE, Matutes E, Cazin B, et al: High remission rate in T-cell prolymphocytic leukemia with CAMPATH-1H. Blood 98:1721-1726, 2001
-
(2001)
Blood
, vol.98
, pp. 1721-1726
-
-
Dearden, C.E.1
Matutes, E.2
Cazin, B.3
-
30
-
-
0036139106
-
Campath-1H treatment of T-cell prolymphocytic leukemia in patients for whom at least one prior chemotherapy regimen has failed
-
Keating MJ, Cazin B, Coutré S, et al: Campath-1H treatment of T-cell prolymphocytic leukemia in patients for whom at least one prior chemotherapy regimen has failed. J Clin Oncol 20:205-213, 2002
-
(2002)
J Clin Oncol
, vol.20
, pp. 205-213
-
-
Keating, M.J.1
Cazin, B.2
Coutré, S.3
-
31
-
-
0037085770
-
CAMPATH-1H and fludarabine in combination are highly active in refractory chronic lymphocytic leukemia
-
Kennedy B, Rawstron A, Carter C, et al: CAMPATH-1H and fludarabine in combination are highly active in refractory chronic lymphocytic leukemia. Blood 99:2245-2247, 2002
-
(2002)
Blood
, vol.99
, pp. 2245-2247
-
-
Kennedy, B.1
Rawstron, A.2
Carter, C.3
-
32
-
-
0037860441
-
A phase II trial of fludarabine followed by alemtuzumab (CAMPATH-1H) in previously untreated chronic lymphocytic leukemia (CLL) patients with active disease: Cancer and Leukemia Group B (CALGB) Study 19901
-
abstr 772
-
Rai KR, Byrd JC, Peterson B, et al: A phase II trial of fludarabine followed by alemtuzumab (CAMPATH-1H) in previously untreated chronic lymphocytic leukemia (CLL) patients with active disease: Cancer and Leukemia Group B (CALGB) Study 19901. Blood 100:205a, 2002 (abstr 772)
-
(2002)
Blood
, vol.100
-
-
Rai, K.R.1
Byrd, J.C.2
Peterson, B.3
-
33
-
-
0034104375
-
Signaling events involved in anti-CD20-induced apoptosis of malignant human B cells
-
Shan D, Ledbetter JA, Press OW: Signaling events involved in anti-CD20-induced apoptosis of malignant human B cells. Cancer Immunol Immunother 48:673-683, 2000
-
(2000)
Cancer Immunol Immunother
, vol.48
, pp. 673-683
-
-
Shan, D.1
Ledbetter, J.A.2
Press, O.W.3
-
34
-
-
0345337254
-
Rituximab chimeric anti-CD20 monoclonal antibody therapy of relapsed indolent lymphoma: Half of patients respond to a four-dose treatment program
-
McLaughlin P, Grillo-López AJ, Link BK, et al: Rituximab chimeric anti-CD20 monoclonal antibody therapy of relapsed indolent lymphoma: Half of patients respond to a four-dose treatment program. J Clin Oncol 16:2825-2833, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 2825-2833
-
-
McLaughlin, P.1
Grillo-López, A.J.2
Link, B.K.3
-
35
-
-
1842368507
-
IDEC-C2B8 (rituximab) anti-CD20- monoclonal antibody therapy in patients with relapsed low-grade non-Hodgkin's lymphoma
-
Maloney DG, Grillo-López AJ, White CA, et al: IDEC-C2B8 (rituximab) anti-CD20- monoclonal antibody therapy in patients with relapsed low-grade non-Hodgkin's lymphoma. Blood 90:2188-2195, 1997
-
(1997)
Blood
, vol.90
, pp. 2188-2195
-
-
Maloney, D.G.1
Grillo-López, A.J.2
White, C.A.3
-
36
-
-
0032931320
-
IDEC-C2B8 anti-CD20 (rituximab) immunotherapy in patients with low-grade non-Hodgkin's lymphoma and lymphoproliferative disorders: Evaluation of response on 48 patients
-
Nguyen DT, Amess JA, Doughty H, et al: IDEC-C2B8 anti-CD20 (rituximab) immunotherapy in patients with low-grade non-Hodgkin's lymphoma and lymphoproliferative disorders: Evaluation of response on 48 patients. Eur J Haematol 62:76-82, 1999
-
(1999)
Eur J Haematol
, vol.62
, pp. 76-82
-
-
Nguyen, D.T.1
Amess, J.A.2
Doughty, H.3
-
37
-
-
0032791210
-
Extended rituximab (anti-CD20 monoclonal antibody) therapy for relapsed or refractory low-grade or follicular non-Hodgkin's lymphoma
-
Piro LD, White CA, Grillo-Lopez AJ, et al: Extended rituximab (anti-CD20 monoclonal antibody) therapy for relapsed or refractory low-grade or follicular non-Hodgkin's lymphoma. Ann Oncol 10:655-661, 1999
-
(1999)
Ann Oncol
, vol.10
, pp. 655-661
-
-
Piro, L.D.1
White, C.A.2
Grillo-Lopez, A.J.3
-
38
-
-
0033214207
-
Cytokine-release syndrome in patients with B-cell chronic lymphocytic leukemia and high lymphocyte counts after treatment with an anti-CD20 monoclonal antibody (rituximab, IDEC-C2B8)
-
Winkler U, Jensen M, Manzke O, et al: Cytokine-release syndrome in patients with B-cell chronic lymphocytic leukemia and high lymphocyte counts after treatment with an anti-CD20 monoclonal antibody (rituximab, IDEC-C2B8). Blood 94:2217-2224, 1999
-
(1999)
Blood
, vol.94
, pp. 2217-2224
-
-
Winkler, U.1
Jensen, M.2
Manzke, O.3
-
39
-
-
0033968522
-
European phase II study of rituximab (chimeric anti-CD20 monoclonal antibody) for patients with newly diagnosed mantle-cell lymphoma and previously treated mantle-cell lymphoma, immunocytoma, and small B-cell lymphocytic lymphoma
-
Foran JM, Rohatiner AZ, Cunningham D, et al: European phase II study of rituximab (chimeric anti-CD20 monoclonal antibody) for patients with newly diagnosed mantle-cell lymphoma and previously treated mantle-cell lymphoma, immunocytoma, and small B-cell lymphocytic lymphoma. J Clin Oncol 18:317-324, 2000
-
(2000)
J Clin Oncol
, vol.18
, pp. 317-324
-
-
Foran, J.M.1
Rohatiner, A.Z.2
Cunningham, D.3
-
40
-
-
0035469851
-
Rituximab therapy of patients with B-cell chronic lymphocytic leukemia
-
Huhn D, von Schilling C, Wilhelm M, et al: Rituximab therapy of patients with B-cell chronic lymphocytic leukemia. Blood 98:1326-1331, 2001
-
(2001)
Blood
, vol.98
, pp. 1326-1331
-
-
Huhn, D.1
von Schilling, C.2
Wilhelm, M.3
-
41
-
-
0035871445
-
Rituximab using a thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity
-
Byrd JC, Murphy T, Howard RS, et al: Rituximab using a thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity. J Clin Oncol 19:2153-2164, 2001
-
(2001)
J Clin Oncol
, vol.19
, pp. 2153-2164
-
-
Byrd, J.C.1
Murphy, T.2
Howard, R.S.3
-
42
-
-
0035871441
-
Rituximab dose-escalation trial in chronic lymphocytic leukemia
-
O'Brien SM, Kantarjian H, Thomas DA, et al: Rituximab dose-escalation trial in chronic lymphocytic leukemia. J Clin Oncol 19:2165-2170, 2001
-
(2001)
J Clin Oncol
, vol.19
, pp. 2165-2170
-
-
O'Brien, S.M.1
Kantarjian, H.2
Thomas, D.A.3
-
43
-
-
0034657295
-
Rituximab monoclonal antibody as initial systemic therapy for patients with low-grade non-Hodgkin's lymphoma
-
Hainsworth JD, Burris HA III, Morrissey LH, et al: Rituximab monoclonal antibody as initial systemic therapy for patients with low-grade non-Hodgkin's lymphoma. Blood 95:3052-3056, 2000
-
(2000)
Blood
, vol.95
, pp. 3052-3056
-
-
Hainsworth, J.D.1
Burris III, H.A.2
Morrissey, L.H.3
-
44
-
-
79951658129
-
Single agent rituxan in early stage chronic lymphocytic leukemia (CLL)
-
abstr 1533
-
Thomas DA, O'Brien S, Giles FJ, et al: Single agent rituxan in early stage chronic lymphocytic leukemia (CLL). Blood 98:364a, 2001 (abstr 1533)
-
(2001)
Blood
, vol.98
-
-
Thomas, D.A.1
O'Brien, S.2
Giles, F.J.3
-
45
-
-
0038446696
-
Circulating CD20 is detectable in the plasma of patients with chronic lymphocytic leukemia and is of prognostic significance
-
Manshouri T, Do KA, Wang X, et al: Circulating CD20 is detectable in the plasma of patients with chronic lymphocytic leukemia and is of prognostic significance. Blood 101:2507-2513, 2003
-
(2003)
Blood
, vol.101
, pp. 2507-2513
-
-
Manshouri, T.1
Do, K.A.2
Wang, X.3
-
46
-
-
0029981025
-
National Cancer Institute-Sponsored Working Group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment
-
Cheson BD, Bennett JM, Grever M, et al: National Cancer Institute-Sponsored Working Group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment. Blood 87:4990-4997, 1996
-
(1996)
Blood
, vol.87
, pp. 4990-4997
-
-
Cheson, B.D.1
Bennett, J.M.2
Grever, M.3
-
47
-
-
0035065041
-
Effective treatment with rituximab in a patient with refractory prolymphocytoid transformed B-chronic lymphocytic leukemia and Evan's syndrome
-
Seipelt G, Bohme A, Koschmieder S, et al: Effective treatment with rituximab in a patient with refractory prolymphocytoid transformed B-chronic lymphocytic leukemia and Evan's syndrome. Ann Hematol 80:170-173, 2001
-
(2001)
Ann Hematol
, vol.80
, pp. 170-173
-
-
Seipelt, G.1
Bohme, A.2
Koschmieder, S.3
-
48
-
-
79960970664
-
Rituximab as first-line and maintenance therapy for patients with small lymphocytic lymphoma (SLL) and chronic lymphocytic leukemia (CLL)
-
abstr 1530
-
Hainsworth JD, Litchy S, Burris HA, et al: Rituximab as first-line and maintenance therapy for patients with small lymphocytic lymphoma (SLL) and chronic lymphocytic leukemia (CLL). Blood 98:363a, 2001 (abstr 1530)
-
(2001)
Blood
, vol.98
-
-
Hainsworth, J.D.1
Litchy, S.2
Burris, H.A.3
-
49
-
-
0003273905
-
Rituximab added to fludarabine improves response in previously untreated chronic lymphocytic leukemia: Preliminary results from CALGB 9712
-
abstr 1116
-
Byrd JC, Peterson B, Park K, et al: Rituximab added to fludarabine improves response in previously untreated chronic lymphocytic leukemia: Preliminary results from CALGB 9712. Proc Am Soc Clin Oncol 20:280a, 2001 (abstr 1116)
-
(2001)
Proc Am Soc Clin Oncol
, vol.20
-
-
Byrd, J.C.1
Peterson, B.2
Park, K.3
-
50
-
-
0030800131
-
Chimeric anti-CD20 (IDEC-C2B8) monoclonal antibody sensitizes a B cell lymphoma cell line to cell killing by cytotoxic drugs
-
Demidem A, Lam T, Alas S, et al: Chimeric anti-CD20 (IDEC-C2B8) monoclonal antibody sensitizes a B cell lymphoma cell line to cell killing by cytotoxic drugs. Cancer Biother Radiopharm 12:177-186, 1997
-
(1997)
Cancer Biother Radiopharm
, vol.12
, pp. 177-186
-
-
Demidem, A.1
Lam, T.2
Alas, S.3
-
51
-
-
0034894958
-
Inhibition of interleukin 10 by rituximab results in down-regulation of bcl-2 and sensitization of B-cell non-Hodgkin's lymphoma to apoptosis
-
Alas S, Emmanoulides C, Bonavida B: Inhibition of interleukin 10 by rituximab results in down-regulation of bcl-2 and sensitization of B-cell non-Hodgkin's lymphoma to apoptosis. Clin Cancer Res 7:709-723, 2001
-
(2001)
Clin Cancer Res
, vol.7
, pp. 709-723
-
-
Alas, S.1
Emmanoulides, C.2
Bonavida, B.3
-
52
-
-
0035393595
-
Rituximab inactivates signal transducer and activator of transcription 3 (STAT3) activity in B-non-Hodgkin's lymphoma through inhibition of the interleukin 10 autocrine/paracrine loop and results in down-regulation of bcl-2 and sensitization to cytotoxic drugs
-
Alas S, Bonavida B: Rituximab inactivates signal transducer and activator of transcription 3 (STAT3) activity in B-non-Hodgkin's lymphoma through inhibition of the interleukin 10 autocrine/paracrine loop and results in down-regulation of bcl-2 and sensitization to cytotoxic drugs. Cancer Res 61:5137-5144, 2001
-
(2001)
Cancer Res
, vol.61
, pp. 5137-5144
-
-
Alas, S.1
Bonavida, B.2
-
53
-
-
0033991523
-
Synergistic cytotoxicity of iodine-131-anti-CD20 antibodies and chemotherapy for treatment of B-cell lymphomas
-
Johnson TA, Press OW: Synergistic cytotoxicity of iodine-131-anti-CD20 antibodies and chemotherapy for treatment of B-cell lymphomas. Int J Cancer 85:104-112, 2000
-
(2000)
Int J Cancer
, vol.85
, pp. 104-112
-
-
Johnson, T.A.1
Press, O.W.2
-
54
-
-
79960970593
-
Phase H-study of rituximab in combination with fludarabine in patients (pts) with chronic lymphocytic leukemia (CLL)
-
abstr 1534
-
Schulz H, Klein SK, Rehwald U, et al: Phase H-study of rituximab in combination with fludarabine in patients (pts) with chronic lymphocytic leukemia (CLL). Blood 98:364a, 2001 (abstr 1534)
-
(2001)
Blood
, vol.98
-
-
Schulz, H.1
Klein, S.K.2
Rehwald, U.3
-
55
-
-
79960971391
-
Update of results of the combination of fludarabine, cyclophosphamide and rituximab for previously treated patients with chronic lymphocytic leukemia (CLL)
-
abstr 2650
-
Garcia-Manero O, O'Brien S, Cortes J, et al: Update of results of the combination of fludarabine, cyclophosphamide and rituximab for previously treated patients with chronic lymphocytic leukemia (CLL). Blood 98:633a, 2001 (abstr 2650)
-
(2001)
Blood
, vol.98
-
-
Garcia-Manero, O.1
O'Brien, S.2
Cortes, J.3
-
56
-
-
79960970873
-
Combined fludarabine, cyclophosphamide, and rituximab achieves a high complete remission rate as initial treatment for chronic lymphocytic leukemia
-
abstr 3210
-
Wierda W, O'Brien S, Albitar M, et al: Combined fludarabine, cyclophosphamide, and rituximab achieves a high complete remission rate as initial treatment for chronic lymphocytic leukemia. Blood 98:771a, 2001 (abstr 3210)
-
(2001)
Blood
, vol.98
-
-
Wierda, W.1
O'Brien, S.2
Albitar, M.3
-
57
-
-
79960971471
-
Successful treatment of pure red cell aplasia (PRA) with rituxan in patients with CLL
-
abstr 914
-
Ghazal HH: Successful treatment of pure red cell aplasia (PRA) with rituxan in patients with CLL. Blood 98:219a, 2001 (abstr 914)
-
(2001)
Blood
, vol.98
-
-
Ghazal, H.H.1
-
58
-
-
0037105458
-
Rituximab treatment of refractory fludarabine-associated immune thrombocytopenia in chronic lymphocytic leukemia
-
Hegde UP, Wilson WH, White T, et al: Rituximab treatment of refractory fludarabine-associated immune thrombocytopenia in chronic lymphocytic leukemia. Blood 100:2260-2262, 2002
-
(2002)
Blood
, vol.100
, pp. 2260-2262
-
-
Hegde, U.P.1
Wilson, W.H.2
White, T.3
-
59
-
-
79960970604
-
Phase I study of rituximab and CAMPATH-1H in patients with relapsed or refractory chronic lymphocytic leukemia
-
abstr 1536
-
Nabhan C, Tallman MS, Riley MB, et al: Phase I study of rituximab and CAMPATH-1H in patients with relapsed or refractory chronic lymphocytic leukemia. Blood 98:365a, 2001 (abstr 1536)
-
(2001)
Blood
, vol.98
-
-
Nabhan, C.1
Tallman, M.S.2
Riley, M.B.3
-
60
-
-
84871468301
-
-
Faderl S, Thomas DA, O'Brien S, et al: Combined use of alemtuzumab and rituximab in patients with relapsed and refractory chronic lymphoid malignancies: An update of the M. D. Anderson experience. Blood 100:206a, 2002 (abstr 775)
-
Faderl S, Thomas DA, O'Brien S, et al: Combined use of alemtuzumab and rituximab in patients with relapsed and refractory chronic lymphoid malignancies: An update of the M. D. Anderson experience. Blood 100:206a, 2002 (abstr 775)
-
-
-
-
61
-
-
26144480276
-
Phase II trial of the diphtheria fusion protein ONTAK in patients with fludarabine refractory chronic lymphocytic leukemia (CLL)
-
abstr 4901
-
Frankel AE, Patrick CL, Powell BL: Phase II trial of the diphtheria fusion protein ONTAK in patients with fludarabine refractory chronic lymphocytic leukemia (CLL). Blood 98:289b, 2001 (abstr 4901)
-
(2001)
Blood
, vol.98
-
-
Frankel, A.E.1
Patrick, C.L.2
Powell, B.L.3
-
62
-
-
0034015672
-
Phase I and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma
-
Waters JS, Webb A, Cunningham D, et al: Phase I and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma. J Clin Oncol 18:1809-1811, 2000
-
(2000)
J Clin Oncol
, vol.18
, pp. 1809-1811
-
-
Waters, J.S.1
Webb, A.2
Cunningham, D.3
-
63
-
-
77958111332
-
Combined therapy with antisense BCL-2 oligonucleolides (AS-BCL2-ODN) + alpha-CD20 monoclonal antibody in scid/human lymphoma xenografts
-
abstr 1458
-
Smith M, Joshi I, Jin F: Combined therapy with antisense BCL-2 oligonucleolides (AS-BCL2-ODN) + alpha-CD20 monoclonal antibody in scid/human lymphoma xenografts. Blood 96:338a, 2000 (abstr 1458)
-
(2000)
Blood
, vol.96
-
-
Smith, M.1
Joshi, I.2
Jin, F.3
-
64
-
-
0033506258
-
Infusion reactions associated with the therapeutic use of monoclonal antibodies in the treatment of malignancy
-
Dillman RO: Infusion reactions associated with the therapeutic use of monoclonal antibodies in the treatment of malignancy. Cancer Metastasis Rev 18:465-471, 1999
-
(1999)
Cancer Metastasis Rev
, vol.18
, pp. 465-471
-
-
Dillman, R.O.1
-
65
-
-
0033016566
-
Rituximab therapy in hematologic malignancy patients with circulating tumor cells: Association with increased infusion-related side effects and rapid blood tumor clearance
-
Byrd JC, Waselenko JK, Maneatis T, et al: Rituximab therapy in hematologic malignancy patients with circulating tumor cells: Association with increased infusion-related side effects and rapid blood tumor clearance. J Clin Oncol 17:791-795, 1999
-
(1999)
J Clin Oncol
, vol.17
, pp. 791-795
-
-
Byrd, J.C.1
Waselenko, J.K.2
Maneatis, T.3
-
66
-
-
0031831522
-
Tumor lysis syndrome: An uncommon complication of fludarabine therapy of chronic lymphocytic leukemia
-
Cheson BD, Frame JN, Vena D, et al: Tumor lysis syndrome: An uncommon complication of fludarabine therapy of chronic lymphocytic leukemia. J Clin Oncol 16:2313-2320, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 2313-2320
-
-
Cheson, B.D.1
Frame, J.N.2
Vena, D.3
-
67
-
-
0043135538
-
Phase I/II trial of epratuzumab (humanized anti-CD22 antibody) in non-Hodgkin's lymphoma (NHL)
-
abstr 1388
-
Leonard JP, Coleman M, Matthews JC, et al: Phase I/II trial of epratuzumab (humanized anti-CD22 antibody) in non-Hodgkin's lymphoma (NHL). Blood 100:358a, 2002 (abstr 1388)
-
(2002)
Blood
, vol.100
-
-
Leonard, J.P.1
Coleman, M.2
Matthews, J.C.3
-
68
-
-
79960971573
-
Induction of apoptosis by IDEC-152 (anti-CD23) in lymphoma cells
-
abstr 1545
-
Pathan N, Hariharan K, Hopkins M, et al: Induction of apoptosis by IDEC-152 (anti-CD23) in lymphoma cells. Blood 98:367a, 2001 (abstr 1545)
-
(2001)
Blood
, vol.98
-
-
Pathan, N.1
Hariharan, K.2
Hopkins, M.3
-
69
-
-
0003351083
-
Phase I trial of humanized ID10 (Hu1D10) monoclonal antibody targeting class H molecules in patients with relapsed lymphoma
-
abstr 86
-
Link BK, Wang H, Byrd JC, et al: Phase I trial of humanized ID10 (Hu1D10) monoclonal antibody targeting class H molecules in patients with relapsed lymphoma. Proc Am Soc Clin Oncol 19:24a, 2000 (abstr 86)
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
-
-
Link, B.K.1
Wang, H.2
Byrd, J.C.3
-
70
-
-
79960970576
-
A phase 11 study of Remitogen (Hu1D10), a humanized monoclonal antibody in patients with relapsed or refractory follicular, small lymphocytic, or marginal zone/MALT B-cell lymphomas
-
abstr 2540
-
Link BK, Kahl B, Czuczman M, et al: A phase 11 study of Remitogen (Hu1D10), a humanized monoclonal antibody in patients with relapsed or refractory follicular, small lymphocytic, or marginal zone/MALT B-cell lymphomas. Blood 98:606a, 2001 (abstr 2540)
-
(2001)
Blood
, vol.98
-
-
Link, B.K.1
Kahl, B.2
Czuczman, M.3
-
71
-
-
0038535838
-
Phase I study of combination rituximab (CD20) and apolizomab (Hu1D10) monoclonal antibody therapy in previously treated B-cell lymphoma and chronic lymphocytic leukemia
-
abstr 1389
-
Hedge U, White T, Stetler-Stevenson M, et al: Phase I study of combination rituximab (CD20) and apolizomab (Hu1D10) monoclonal antibody therapy in previously treated B-cell lymphoma and chronic lymphocytic leukemia. Blood 100:358a, 2002 (abstr 1389)
-
(2002)
Blood
, vol.100
-
-
Hedge, U.1
White, T.2
Stetler-Stevenson, M.3
-
72
-
-
0031045135
-
Basic fibroblast growth factor (bFGF) upregulates the expression of bcl-2 in B cell chronic lymphocytic leukemia cell lines resulting in delaying apoptosis
-
König A, Menzel T, Lynen S, et al: Basic fibroblast growth factor (bFGF) upregulates the expression of bcl-2 in B cell chronic lymphocytic leukemia cell lines resulting in delaying apoptosis. Leukemia 11:258-265, 1997
-
(1997)
Leukemia
, vol.11
, pp. 258-265
-
-
König, A.1
Menzel, T.2
Lynen, S.3
-
73
-
-
0003305378
-
Successful long-term therapy with bevacizumab (Avastin) in solid tumors
-
abstr 32
-
Langmuir VK, Cobleigh MA, Herbst RS, et al: Successful long-term therapy with bevacizumab (Avastin) in solid tumors. Proc Am Soc Clin Oncol 21:9a, 2002 (abstr 32)
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Langmuir, V.K.1
Cobleigh, M.A.2
Herbst, R.S.3
-
74
-
-
0036282502
-
Inhibition of angiogenesis: Treatment options for patients with metastatic prostate cancer
-
Figg D, Fruger EA, Price DK: Inhibition of angiogenesis: treatment options for patients with metastatic prostate cancer. Invest New Drugs 20:183-194, 2002
-
(2002)
Invest New Drugs
, vol.20
, pp. 183-194
-
-
Figg, D.1
Fruger, E.A.2
Price, D.K.3
-
75
-
-
0038714190
-
Timed sequential therapy (TST) of relapsed and refractory adult acute myelogenous leukemia (AML) with the anti-vascular endothelial growth factor (VEGF) monoclonal antibody bevacizumab
-
abstr 744
-
Karp JE, Gojo I, Gocke CD, et al: Timed sequential therapy (TST) of relapsed and refractory adult acute myelogenous leukemia (AML) with the anti-vascular endothelial growth factor (VEGF) monoclonal antibody bevacizumab. Blood 100:198a, 2002 (abstr 744)
-
(2002)
Blood
, vol.100
-
-
Karp, J.E.1
Gojo, I.2
Gocke, C.D.3
-
76
-
-
0026586054
-
Serotherapy of B-cell neoplasms with anti-B4-blocked ricin: A phase 1 trial of daily bolus infusion
-
Grossbard ML, Freedman AS, Ritz J, et al: Serotherapy of B-cell neoplasms with anti-B4-blocked ricin: A phase 1 trial of daily bolus infusion. Blood 79:576-585, 1992
-
(1992)
Blood
, vol.79
, pp. 576-585
-
-
Grossbard, M.L.1
Freedman, A.S.2
Ritz, J.3
-
77
-
-
0027502253
-
Anti-B4-blocked ricin: A phase I trial of 7-day continuous infusion in patients with B-cell neoplasms
-
Grossbard ML, Lambert JM, Goldmacher VS, et al: Anti-B4-blocked ricin: A phase I trial of 7-day continuous infusion in patients with B-cell neoplasms. J Clin Oncol 11:726-737, 1993
-
(1993)
J Clin Oncol
, vol.11
, pp. 726-737
-
-
Grossbard, M.L.1
Lambert, J.M.2
Goldmacher, V.S.3
-
78
-
-
0031783693
-
Phase II clinical trial of bolus infusion of anti-B4 blocked ricin immunoconjugate in patients with relapsed B-cell non-Hodgkin's lymphoma
-
Multani PS, O'Day S, Nadler LM, et al: Phase II clinical trial of bolus infusion of anti-B4 blocked ricin immunoconjugate in patients with relapsed B-cell non-Hodgkin's lymphoma. Clin Cancer Res 4:2599-2604, 1998
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2599-2604
-
-
Multani, P.S.1
O'Day, S.2
Nadler, L.M.3
-
79
-
-
0035954624
-
Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia
-
Kreitman RJ, Wilson WH, Bergeron K, et al: Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia. N Engl J Med 345:241-247, 2001
-
(2001)
N Engl J Med
, vol.345
, pp. 241-247
-
-
Kreitman, R.J.1
Wilson, W.H.2
Bergeron, K.3
-
80
-
-
0026628118
-
Phase I trial of an interleukin-2 (IL-2) fusion toxin (DAB486IL-2) in hematologic malignancies expression the IL-2 receptor
-
LeMaistre CF, Meneghetti C, Rosenblum M, et al: Phase I trial of an interleukin-2 (IL-2) fusion toxin (DAB486IL-2) in hematologic malignancies expression the IL-2 receptor. Blood 79:2547-2554, 1992
-
(1992)
Blood
, vol.79
, pp. 2547-2554
-
-
LeMaistre, C.F.1
Meneghetti, C.2
Rosenblum, M.3
-
81
-
-
33645960035
-
Diphtheria fusion protein OhJTAK therapy of patients with fludarabine refractory chronic lymphocytic leukemia
-
abstr 1071
-
Fleming DR, Powell BL, Patrick CL, et al: Diphtheria fusion protein OhJTAK therapy of patients with fludarabine refractory chronic lymphocytic leukemia. Proc Am Soc Clin Oncol 19:268a, 2002 (abstr 1071)
-
(2002)
Proc Am Soc Clin Oncol
, vol.19
-
-
Fleming, D.R.1
Powell, B.L.2
Patrick, C.L.3
-
82
-
-
0037102128
-
Radiolabeled anti-CD20 monoclonal antibodies for the treatment of B-cell lymphoma
-
Dillman RO: Radiolabeled anti-CD20 monoclonal antibodies for the treatment of B-cell lymphoma. J Clin Oncol 20:3545-3547, 2002
-
(2002)
J Clin Oncol
, vol.20
, pp. 3545-3547
-
-
Dillman, R.O.1
-
83
-
-
0037438974
-
Radioimmunotherapy of non-Hodgkin's lymphomas
-
Cheson BD: Radioimmunotherapy of non-Hodgkin's lymphomas. Blood 101:391-398, 2003
-
(2003)
Blood
, vol.101
, pp. 391-398
-
-
Cheson, B.D.1
-
84
-
-
0023137637
-
Two new monoclonal antibodies, Lym-1 and Lym-2, reactive with human B-lymphocytes and derived tumors, with immunodiagnostic and immunotherapeutic potential
-
Epstein AL, Marder RJ, Winter JN, et al: Two new monoclonal antibodies, Lym-1 and Lym-2, reactive with human B-lymphocytes and derived tumors, with immunodiagnostic and immunotherapeutic potential. Cancer Res 47:830-840, 1987
-
(1987)
Cancer Res
, vol.47
, pp. 830-840
-
-
Epstein, A.L.1
Marder, R.J.2
Winter, J.N.3
-
85
-
-
0002768698
-
Pilot studies of radioimmunotherapy of B cell lymphoma and leukemia using I-131 Lym-1 monoclonal antibody
-
DeNardo SJ, DeNardo GL, O'Grady LF, et al: Pilot studies of radioimmunotherapy of B cell lymphoma and leukemia using I-131 Lym-1 monoclonal antibody. Antibody Immunoconjugates Radiopharm 1:17-33, 1988
-
(1988)
Antibody Immunoconjugates Radiopharm
, vol.1
, pp. 17-33
-
-
DeNardo, S.J.1
DeNardo, G.L.2
O'Grady, L.F.3
-
87
-
-
27944475631
-
Impact of Lym-1 radioimmunoconjugate on refractory chronic lymphocytic leukemia (CLL)
-
abstr 1171
-
Lewis JP, DeNardo GL, DeNardo SJ, et al: Impact of Lym-1 radioimmunoconjugate on refractory chronic lymphocytic leukemia (CLL). Blood 76:295a, 1990 (abstr 1171)
-
(1990)
Blood
, vol.76
-
-
Lewis, J.P.1
DeNardo, G.L.2
DeNardo, S.J.3
-
88
-
-
0028344048
-
Effect of Lym-1 radioimmunoconjugate on refractory chronic lymphocytic leukemia
-
DeNardo GJ, Lewis JP, DeNardo SJ, et al: Effect of Lym-1 radioimmunoconjugate on refractory chronic lymphocytic leukemia. Cancer 73:1425-1432, 1994
-
(1994)
Cancer
, vol.73
, pp. 1425-1432
-
-
DeNardo, G.J.1
Lewis, J.P.2
DeNardo, S.J.3
-
89
-
-
0024602608
-
A phase Ia clinical trial of LYM-1 monoclonal antibody serotherapy in patients with refractory B cell malignancies
-
Hu E, Epstein AL, Naeve GS, et al: A phase Ia clinical trial of LYM-1 monoclonal antibody serotherapy in patients with refractory B cell malignancies. Hematol Oncol 7:155-166, 1989
-
(1989)
Hematol Oncol
, vol.7
, pp. 155-166
-
-
Hu, E.1
Epstein, A.L.2
Naeve, G.S.3
-
90
-
-
0000805114
-
Iodine I131 tositumomab for patients with small lymphocytic lymphoma (SLL): Overall clinical trial experience
-
abstr 386
-
Kaminski MS, Press OW, Lister TA, et al: Iodine I131 tositumomab for patients with small lymphocytic lymphoma (SLL): Overall clinical trial experience. Blood 94:88a, 1999 (abstr 386)
-
(1999)
Blood
, vol.94
-
-
Kaminski, M.S.1
Press, O.W.2
Lister, T.A.3
-
91
-
-
0035803371
-
Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia
-
Rosenwald A, Alizadeh AA, Widhopf G, et al: Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J Exp Med 194:1639-1647, 2001
-
(2001)
J Exp Med
, vol.194
, pp. 1639-1647
-
-
Rosenwald, A.1
Alizadeh, A.A.2
Widhopf, G.3
-
92
-
-
0037114744
-
Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia
-
Chen L, Widhopf G, Huynh L, et al: Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia. Blood 100:4609-4614, 2002
-
(2002)
Blood
, vol.100
, pp. 4609-4614
-
-
Chen, L.1
Widhopf, G.2
Huynh, L.3
|