Effects of undernutrition on glutamatergic parameters in rat brain

Neurochemical Research

Volumn 28, Issue 8, 2003, Pages 1181-1186

  Rotta, Liane N ^a,b   Schmidt, André P ^a   Mello e Souza, Tadeu ^a   Nogueira, Cristina W ^c   Souza, Karine B ^a   Izquierdo, Ivan A ^a   Perry, Marcos L S ^a   Souza, Diogo O ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

^c FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

Author keywords

Behavioral parameters; Glutamatergic system; Quinolinic acid; Seizures; Undernutrition

Indexed keywords

CONVULSANT AGENT; GLUTAMINE; PROTEIN; QUINOLINIC ACID; SODIUM;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BRAIN CORTEX; BRAIN FUNCTION; CELL MEMBRANE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DIET; LOCOMOTION; MALE; MALNUTRITION; MEMORY; NONHUMAN; NUTRITION; ONTOGENY; PERINATAL PERIOD; PRIORITY JOURNAL; RAT; SEIZURE;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; GLUTAMIC ACID; MALE; NUTRITION DISORDERS; RATS; RATS, WISTAR;

ANIMALIA;

EID: 0038467446     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1024272227219     Document Type: Article

References (25)

1. Galler, J. R., Shumsky, L. S., and Morgane, P. J. 1995. Malnutrition and brain development. Pages 196-212, In Walker, W. A. and Watkins J. B. (eds.), Nutrition in pediatrics: Basic science and clinical applications, London.
2. Levitsky, D. A. and Strupp, B. J. 1995. Malnutrition and the brain: Changing concepts, changing concerns. J. Nutr. 125: 2212S-2220S.
3. Morgan, B. G. L. and Naismith, D. J. 1992. The effect of early postnatal undernutrition on the growth and development of the rat brain. Brit. J. Nutr. 48:15-23.
4. Wiggins, R. C., Fuller, G., and Enna, S. J. 1984. Undernutrition and the development of brain neurotransmitter systems. Life Sci. 35:2085-2094.
5. Rocha, J. B. and Souza, D. O. 1994. Effects of undernutrition during suckling and early post-weaning on the inhibition by met-enkephalin of striatal adenylate cyclase activity in adult rats. Pharmacol. Toxicol. 75:321-323.
6. A receptor subunit mRNAs in the adult septum. Eur. J. Pharmacol. In press.
7. Izquierdo, I. and Medina, J. H. 1997. Memory formation: The sequence of biochemical events in the hippocampus and its connection to activity in other brain structures. Neurobiol. Learn. Mem. 68:285-316.
8. Ozawa, S., Kamiya, H., and Tsukuki, K. 1998. Glutamate receptors in the mammalian central nervous system. Progr. Neurobiol. 54:581-618.
9. Stone, T. W. 2001. Kynurenines in the CNS: From endogenous obscurity to therapeutic importance. Prog. Neurobiol. 64:185-218.
10. Lara, D. R. Schmidt, A. P. Frizzo, M. E. Burgos, J. S. Ramirez, G., and Souza, D. O. 2001. Effect of orally administered guanosine on seizures and death induced by glutamatergic agents. Brain Res. 912:176-180.
11. Schmidt, A. P., Lara, D. R., Maraschin, J. F., Perla, A. S., and Souza, D. O. 2000. Guanosine and GMP prevent seizures induced by quinolinic acid in mice. Brain Res. 864:40-4311.
12. Tavares, R. G., Tasca, C. I., Santos, C. E., S. Alves, L. B., Porciuncula, L. O. Emanuelli, T., and Souza, D. O. 2002. Quinolinic acid stimulates synaptosomal glutamate release and inhibits glutamate uptake into astrocytes. Neurochem. Int. 40:621-627.
13. Tavares, R. G., Tasca, C. I., Santos, C. E. S., Wajner, M., Souza, D. O., and Dutra-Filho, C. S. 2000. Quinolinic acid inhibits glutamate uptake into synaptic vesicles from rat brain. Neuroreport 27:249-253.
14. Austin-LaFrance, R. J. Morgane, P. J., and Bronzino, J. D. 1991. Prenatal protein malnutrition and hippocampal function: Rapid kindling. Brain Res. Bull. 27:815-818.
15. Bronzino, J. D., Blaise, J. H., Mokler, D. J., Galler, J. R., and Morgane, P. J. 1999. Modulation of paired-pulse responses in the dentate gyrus: Effects of prenatal protein malnutrition. Brain Res. 849:45-57.
16. Horwitz W. 1980. Official methods of analysis of the Association of Official Analytical Chemists. AOAC, Washington, DC.
17. Pellow, S., Chopin, P., File, S. E., and Briley, M. 1985. Validation of open: Closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J. Neurosci. Meth. 14:149-176.
18. Dunkley, P. R., Heath, J. W., Harrison, S. M., Jarvie, P. E., Glenfield, P. J., and Rostas, J. A. 1988. A rapid Percoll gradient procedure for isolation of synaptosomes directly from an S1 fraction: Homogeneity and morphology of subcellular fractions. Brain Res. 441:59-71.
19. Lowry, H. O., Rosenbrough, N. J., Farr, A. L., and Randall, R. J. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265-275.
20. Jones, D. H. and Matus, A. I. 1974. Isolation of synaptic plasma membrane from brain by combined flotation-sedimentation density gradient centrifugation. Biochem. Biophys. Acta 356: 276-287.
21. 3H] glutamate binding to fresh and frozen crude plasma membrane isolated from cerebral cortex of adult rats. Biochem. Mol. Biol. Int. 44:1265-1272.
22. Danbolt, N. C. 2001. Glutamate uptake. Prog. Neurobiol. 65:1-105.
23. Bough, K., Gudi, K., Han, F., Rathod, A., and Eagles, D. 2002. An anticonvulsant profile of the ketogenic diet in the rat. Epilepsy Res. 50:313-325.
24. al-Mudalla, A. S., Levin, B. E., Lust, W. D., and Harik, S. I. 1995. Effects of unbalanced diets on cerebral glucose metabolism in the adult rat. Neurology 45:2261-2265.
25. Bell, M. J., Kochaneck, P. M., Heyes, M. P., Wisniewski, S. R., Sinz, E. H., Clark, R. S. B., Blight, A. R., Marion, D. W., and Adelson, P. D. 1999. Quinolinic acid in the cerebrospinal fluid of children after traumatic injury. Crit. Care Med. 27:493-497.