메뉴 건너뛰기




Volumn 33, Issue 2, 2003, Pages 200-207

A protein methyl transferase, PRMT5, selectively blocks oncogenic ras-p21 mitogenic signal transduction

Author keywords

Insulin; JAK 2 binding protein; Oncogenic ras p21; Protein arginine methyltrasferase (PRMT5)

Indexed keywords

BINDING PROTEIN; INSULIN; METHYLTRANSFERASE INHIBITOR; PEPTIDE; PROTEIN ARGININE METHYLTRANSFERASE 5; PROTEIN METHYLTRANSFERASE; PROTEIN P21; RAS PROTEIN; UNCLASSIFIED DRUG;

EID: 0038460025     PISSN: 00917370     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (9)

References (17)
  • 1
    • 0033950650 scopus 로고    scopus 로고
    • ras- p21-induced cell transformation: Unique signal transduction pathways and implications for the design of new chemotherapeutic agents
    • Pincus MR, Brandt-Rauf PW, Michl J, Friedman FK. ras- p21-induced cell transformation: unique signal transduction pathways and implications for the design of new chemotherapeutic agents. Cancer Invest 2000;18:39-50.
    • (2000) Cancer Invest , vol.18 , pp. 39-50
    • Pincus, M.R.1    Brandt-Rauf, P.W.2    Michl, J.3    Friedman, F.K.4
  • 2
    • 0024465343 scopus 로고
    • Posttranslational processing of p21 ras is two-step and involves carboxymethylation and carboxy-terminal proteolysis
    • Gutierrez L, Magee AI, Marshall CJ, Hancock JF. Posttranslational processing of p21 ras is two-step and involves carboxymethylation and carboxy-terminal proteolysis. EMBO J 1989;8:1093-1098.
    • (1989) EMBO J , vol.8 , pp. 1093-1098
    • Gutierrez, L.1    Magee, A.I.2    Marshall, C.J.3    Hancock, J.F.4
  • 4
    • 0022319149 scopus 로고
    • ras proteins can induce meiosis in Xenopus oocytes
    • Birchmeier C, Broek D, Wigler M. ras proteins can induce meiosis in Xenopus oocytes. Cell 1985;43:615-621.
    • (1985) Cell , vol.43 , pp. 615-621
    • Birchmeier, C.1    Broek, D.2    Wigler, M.3
  • 5
    • 0023117310 scopus 로고
    • Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras proteins
    • Deshpande AK, Kung H-F. Insulin induction of Xenopus laevis oocyte maturation is inhibited by monoclonal antibody against p21 ras proteins. Mol Cell Biol 1987;7:1285-1288.
    • (1987) Mol Cell Biol , vol.7 , pp. 1285-1288
    • Deshpande, A.K.1    Kung, H.-F.2
  • 6
    • 0030855381 scopus 로고    scopus 로고
    • Inhibition of oncogenic and activated wild-type ras-p21 protein-induced oocyte maturation by peptides from the ras binding domain of the raf-p74 protein, identified from molecular dynamics calculations
    • Chung D, Amar S, Glozman A, Chen JM, Friedman FK, Robinson R, Monaco R, Brandt-Rauf PW, Yamaizumi Z, Pincus MR. Inhibition of oncogenic and activated wild-type ras-p21 protein-induced oocyte maturation by peptides from the ras binding domain of the raf-p74 protein, identified from molecular dynamics calculations. J Protein Chem 1997;16:619-629.
    • (1997) J Protein Chem , vol.16 , pp. 619-629
    • Chung, D.1    Amar, S.2    Glozman, A.3    Chen, J.M.4    Friedman, F.K.5    Robinson, R.6    Monaco, R.7    Brandt-Rauf, P.W.8    Yamaizumi, Z.9    Pincus, M.R.10
  • 7
    • 53149085963 scopus 로고    scopus 로고
    • Inhibition of oncogenic and activated wild-type ras-p21 protein-induced peptides from the guanine-nucleotide exchange protein, SOS, identified from molecular dynamics calculations. Selective inhibition of oncogenic ras-p21
    • Chie L, Chen JM, Friedman FK, Chung DL, Amar S, Michl J, Yamaizumi Z, Pincus MR. Inhibition of oncogenic and activated wild-type ras-p21 protein-induced peptides from the guanine-nucleotide exchange protein, SOS, identified from molecular dynamics calculations. Selective inhibition of oncogenic ras-p21. J Protein Chem 2000;18:875-879.
    • (2000) J Protein Chem , vol.18 , pp. 875-879
    • Chie, L.1    Chen, J.M.2    Friedman, F.K.3    Chung, D.L.4    Amar, S.5    Michl, J.6    Yamaizumi, Z.7    Pincus, M.R.8
  • 9
    • 0029789849 scopus 로고    scopus 로고
    • Activation of c-jun NH2-terminal kinase by UV-irradiation is dependent on p21 ras
    • Adler V, Pincus MR, Polotskaya A, Montano X, Friedman F, Ronai Z. Activation of c-jun NH2-terminal kinase by UV-irradiation is dependent on p21 ras. J Biol Chem 1996;271:23304-23309.
    • (1996) J Biol Chem , vol.271 , pp. 23304-23309
    • Adler, V.1    Pincus, M.R.2    Polotskaya, A.3    Montano, X.4    Friedman, F.5    Ronai, Z.6
  • 10
    • 0033615656 scopus 로고    scopus 로고
    • The human homologue of the yeast proteins, skb1 and HSL7 interacts with Jak2 and contains protein methyltransferase activity
    • Pollack BP, Kotenko SV, He W, Izorova L, Barnoski BL, Pestka S. The human homologue of the yeast proteins, skb1 and HSL7 interacts with Jak2 and contains protein methyltransferase activity. J Biol Chem 1999;274:31531-31542.
    • (1999) J Biol Chem , vol.274 , pp. 31531-31542
    • Pollack, B.P.1    Kotenko, S.V.2    He, W.3    Izorova, L.4    Barnoski, B.L.5    Pestka, S.6
  • 13
    • 0035980018 scopus 로고    scopus 로고
    • PRMT5 (Janus Kinase-Binding Protein 1) catalyzes the formation of symmetric dimethyl-arginine residues in proteins
    • Branscombe TL, Frankel A, Lee J-H, Cook JR, Yang Z, Pestka S, Clarke S. PRMT5 (Janus Kinase-Binding Protein 1) catalyzes the formation of symmetric dimethyl-arginine residues in proteins. J Biol Chem 2001;276:32971-32976.
    • (2001) J Biol Chem , vol.276 , pp. 32971-32976
    • Branscombe, T.L.1    Frankel, A.2    Lee, J.-H.3    Cook, J.R.4    Yang, Z.5    Pestka, S.6    Clarke, S.7
  • 15
    • 0028037617 scopus 로고
    • Adenosine and homocysteine together enhance TNF-mediated cyrotoxicity but do not alter activation of nuclear factor-KB in L929 cells
    • Bergmann S, Shatrov V, Ratter F, Schiemann S, Schulze-Osthoff K, Lehmann V. Adenosine and homocysteine together enhance TNF-mediated cyrotoxicity but do not alter activation of nuclear factor-KB in L929 cells. J Immunol 1994;153:1736-1743.
    • (1994) J Immunol , vol.153 , pp. 1736-1743
    • Bergmann, S.1    Shatrov, V.2    Ratter, F.3    Schiemann, S.4    Schulze-Osthoff, K.5    Lehmann, V.6
  • 16
    • 0036638239 scopus 로고    scopus 로고
    • Inhibition of ras-induced oocyte maturation by peptides from ras-p21 and GTPase activating protein (GAP) identified as being effector domains from molecular dynamics calculations
    • Friedman FK, Chie L, Chung D, Robinson R, Brandt-Rauf PW, Yamaizumi Z, Pincus MR. Inhibition of ras-induced oocyte maturation by peptides from ras-p21 and GTPase activating protein (GAP) identified as being effector domains from molecular dynamics calculations. J Protein Chem 2002;21:361-366.
    • (2002) J Protein Chem , vol.21 , pp. 361-366
    • Friedman, F.K.1    Chie, L.2    Chung, D.3    Robinson, R.4    Brandt-Rauf, P.W.5    Yamaizumi, Z.6    Pincus, M.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.