Hsl7p, the yeast homologue of human JBP1, is a protein methyltransferase

Biochemical and Biophysical Research Communications

Volumn 274, Issue 1, 2000, Pages 105-111

  Lee, Jin Hyung ^a   Cook, Jeffry R ^a   Pollack, Brian P ^a   Kinzy, Terri Goss ^a   Norris, David ^b   Pestka, Sidney ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Hsl7p; Janus kinase; Protein methyltransferase; Saccharomyces cerevisiae; Signal transduction

Indexed keywords

BINDING PROTEIN; CYTOCHROME C; FUNGAL PROTEIN; HISTONE; JANUS KINASE; MYELIN BASIC PROTEIN; PROTEIN HS17P; PROTEIN METHYLTRANSFERASE; S ADENOSYLMETHIONINE; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; CATTLE; CONSENSUS SEQUENCE; CONTROLLED STUDY; CROSS LINKING; GENE DISRUPTION; GENETIC COMPLEMENTATION; METHYLATION; NONHUMAN; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; YEAST;

EID: 0033916067     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.3049     Document Type: Article

References (27)

1. Pollack B. P., Kotenko S. V., He W., Izotova L., Barnowski B. L., Pestka S. The human homologue of the yeast proteins skb1 and hsl7p interacts with jak kinases and contains protein methyltransferase activity. J. Biol. Chem. 274:1999;31531-31542.
2. Ma X.-J., Lu Q., Grunstein M. A search for proteins that interact genetically with histone H3 and H4 amino termini uncovers novel regulators of the Swe1 kinase in Saccharomyces cerevisiae. Genes Dev. 10:1996;1327-1340.
3. Gilbreth M., Yang P., Wang D., Frost J., Polverino A., Cobb M. H., Marcus S. The highly conserved skb1 gene encodes a protein that interacts with Shk1, a fission yeast Ste20/PAK homolog. Proc. Natl. Acad. Sci. USA. 93:1996;13802-13807.
4. Fujita A., Tonouchi A., Hiroko T., Inose F., Nagashima T., Satoh R., Tanaka S. Hsl7p, a negative regulator of Ste20p protein kinase in the Saccharomyces cerevisiae filamentous growth-signaling pathway. Proc. Natl. Acad. Sci. USA. 96:1999;8522-8527.
5. Shulewitz M. J., Inouye C. J., Thorner J. Hsl7 localizes to a septin ring and serves as an adapter in a regulatory pathway that relieves tyrosine phosphorylation of Cdc28 protein kinase in Saccharomyces cerevisiae. Mol. Cell Biol. 19:1999;7123-7137.
6. Sherman F., Fink G. R., Hicks J. B. Methods in Yeast Genetics: A Laboratory Manual. 1986;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
7. Ito H., Fukuda Y., Murata K., Kimura A. Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153:1983;163-168.
8. Carr-Schmid A., Valente L., Loik V. I., Williams T., Starita L. M., Kinzy T. G. Mutations in elongation factor 1β, a guanine nucleotide exchange factor, enhance translational fidelity. Mol. Cell. Biol. 19:1999;5257-5266.
9. Niewmierzycka A., Clarke S. S. 274:1999;814-824.
10. Cheng X., Kumar S., Posfai J., Pflugarth J. W., Roberts R. J. Disruption of six novel yeast genes located on chromosome II reveals one gene essential for vegetative growth and two required for sporulation and conferring hypersensitivity to various chemicals. Cell. 74:1993;299-307.
11. Kucharczyk R., Gromadka R., Migdalski A., Slonimski P. P., Rytka J. Disruption of six novel yeast genes located on chromosome II reveals one gene essential for vegetative growth and two required for sporulation and conferring hypersensitivity to various chemicals. Yeast. 15:1999;987-1000.
12. Mao X., Schwer B., Shuman S. A search for proteins that interact genetically with histone H3 and H4 amino termini uncovers novel regulators of the Swe1 kinase in Saccharomyces cerevisiae. Mol. Cell. Biol. 15:1995;4167-4174.
13. Lafontaine D., Delcour J., Glasser A. L., Desgres J., Vandenhaute J. The DIM1 gene responsible for the conserved m6(2)Am6(2)A dimethylation in the 3′-terminal loop of 18 S rRNA is essential in yeast. J. Mol. Biol. 241:1994;492-497.
14. Hrycyna C. A., Sapperstein S. K., Clarke S., Michaelis S. The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins. EMBO J. 10:1991;1699-1709.
15. Sirum-Connolly K., Mason T. L. Functional requirement of a site-specific ribose methylation in ribosomal RNA. Science. 262:1993;1886-1889.
16. Gary J. D., Lin W.-J., Yang M. C., Herschman H. R., Clarke S. The predominant protein-arginine methyltransferase from Saccharomyces cerevisiae. J. Biol. Chem. 271:1996;12585-12594.
17. Henry M. F., Silver P. A. A novel methyltransferase (Hmt1p) modifies poly (A)+-RNA-binding proteins. Mol. Cell Biol. 16:1996;3668-3678.
18. Shen E. C., Henry M. F., Weiss V. H., Valentini S. R., Silver P. A., Lee M. S. Arginine methylation facilitates the nuclear export of hnRNP proteins. Genes Dev. 12:1998;679-691.
19. McBride A. E., Weiss V. H., Kim H. K., Hogle J. M., Silver P. A. Analysis of the yeast arginine methyltransferase Hmt1/Rmt1p and its in vivo function. Cofactor binding and substrate interactions. J. Biol. Chem. 275:2000;3128-3136.
20. Gilbreth M., Yang P., Bartholomeusz G., Pimental R. A., Kansra S., Gadiraju R., Marcus S. Negative regulation of mitosis in fission yeast by the shk1 interacting protein skb1 and its human homolog, Skb1Hs. Proc. Natl. Acad. Sci. USA. 95:1998;14781-14786.
21. Leberer E., Dignard D., Harcus D., Thomas D. Y., Whiteway M. The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signaling components. EMBO J. 11:1992;4815-4824.
22. Roberts R. L., Fink G. R. Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: mating and invasive growth. Genes Dev. 8:1994;2974-2985.
23. Gimeno C. J., Ljungdahl P. O., Styles C. A., Fink G. R. Unipolar cell divisions in the yeast S. cerevisiae lead to filamentous growth: regulation by starvation and RAS. Cell. 6:1992;1077-1090.
24. Mosch H. U., Roberts R. L., Fink G. R. Ras2 signals via the Cdc42/Ste20/mitogen-activated protein kinase module to induce filamentous growth in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA. 93:1996;5352-5356.
25. McMillan J. N., Longtime M. S., Sia R. A. L., Theesfeld C. L., Bardes E. S. G., Pringle J. R., Lew D. J. The morphogenesis checkpoint in Saccharomyces cerevisiae: Cell cycle control of Swe1p degradation by Hsl1p and Hsl7p. Mol. Cell. Biol. 19:1999;6929-6939.
26. Chen D., Ma H., Hong H., Koh S. S., Huang S.-M., Schurter B. T., Aswad D. W., Stallcup M. R. Regulation of transcription by a protein methyltransferase. Science. 284:1999;2174-2177.
27. Strahl B. D., Allis C. D. The language of covalent histone modifications. Nature. 403:2000;41-45.