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Volumn 41, Issue 6, 2003, Pages 849-855

Adrenomedullin induces direct (endothelium-independent) vasorelaxations and cyclic adenosine monophosphate elevations that are synergistically enhanced by brain natriuretic peptide in isolated rings of rat thoracic aorta

Author keywords

Adenosine monophosphate; Adrenomedullin; Brain natriuretic peptide; Cyclic; Cyclic guanosine monophosphate; Vasorelaxation

Indexed keywords

ADRENOMEDULLIN; BRAIN NATRIURETIC PEPTIDE; CYCLIC AMP; CYCLIC GMP; NITRIC OXIDE; PHOSPHODIESTERASE III INHIBITOR; PHOSPHODIESTERASE INHIBITOR; QUAZINONE; UNCLASSIFIED DRUG;

EID: 0038457678     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200306000-00004     Document Type: Article
Times cited : (12)

References (34)
  • 1
    • 0034453838 scopus 로고    scopus 로고
    • Adrenomedullin, a multifunctional regulatory peptide
    • Hinson JP, Kapas S, Smith DM. Adrenomedullin, a multifunctional regulatory peptide. Endocrine Rev. 2000;21:138-67.
    • (2000) Endocrine Rev , vol.21 , pp. 138-167
    • Hinson, J.P.1    Kapas, S.2    Smith, D.M.3
  • 2
    • 0033305029 scopus 로고    scopus 로고
    • Induction of Max by adrenomedullin and calcitonin gene-related peptide antagonizes endothelial apoptosis
    • Shichiri M, Kato H, Doi M, et al. Induction of Max by adrenomedullin and calcitonin gene-related peptide antagonizes endothelial apoptosis. Mol Endocrinol. 1999;13:1353-63.
    • (1999) Mol Endocrinol , vol.13 , pp. 1353-1363
    • Shichiri, M.1    Kato, H.2    Doi, M.3
  • 3
    • 0033215263 scopus 로고    scopus 로고
    • Adrenomedullin augments nitric oxide and tetrahydrobiopterin synthesis in cytokine-stimulated vascular smooth muscle cells
    • Hattori Y, Nakanishi N, Gross SS, et al. Adrenomedullin augments nitric oxide and tetrahydrobiopterin synthesis in cytokine-stimulated vascular smooth muscle cells. Cardiovasc Res. 1999;44:207-14.
    • (1999) Cardiovasc Res , vol.44 , pp. 207-214
    • Hattori, Y.1    Nakanishi, N.2    Gross, S.S.3
  • 4
    • 0029886335 scopus 로고    scopus 로고
    • Adrenomedullin increases inducible nitric oxide synthase in rat vascular smooth muscle cells stimulated with interleukin-1
    • Ikeda U, Kanbe T, Shimada K. Adrenomedullin increases inducible nitric oxide synthase in rat vascular smooth muscle cells stimulated with interleukin-1. Hypertension. 1996;27:1240-4.
    • (1996) Hypertension , vol.27 , pp. 1240-1244
    • Ikeda, U.1    Kanbe, T.2    Shimada, K.3
  • 5
    • 0028233752 scopus 로고
    • Adrenomedullin stimulates cyclic AMP formation in rat vascular smooth muscle cells
    • Ishizaka Y, Ishizaka Y, Tanaka M, et al. Adrenomedullin stimulates cyclic AMP formation in rat vascular smooth muscle cells. Biochem Biophys Res Commun. 1994;200:642-6.
    • (1994) Biochem Biophys Res Commun , vol.200 , pp. 642-646
    • Ishizaka, Y.1    Ishizaka, Y.2    Tanaka, M.3
  • 6
    • 0028324987 scopus 로고
    • Specific receptors for adrenomedullin in cultured rat vascular smooth muscle cells
    • Eguchi S, Hirata Y, Kano H, et al. Specific receptors for adrenomedullin in cultured rat vascular smooth muscle cells. FEBSLett. 1994;340:226-30.
    • (1994) FEBSLett , vol.340 , pp. 226-230
    • Eguchi, S.1    Hirata, Y.2    Kano, H.3
  • 7
    • 0031944896 scopus 로고    scopus 로고
    • Effects of adrenomedullin and calcitonin gene-related peptide on contractions of the rat aorta and porcine coronary artery
    • Yoshimoto R, Mitsui-Saito M, Ozaki H, et al. Effects of adrenomedullin and calcitonin gene-related peptide on contractions of the rat aorta and porcine coronary artery. Br J Pharmacol. 1998;123:1645-54.
    • (1998) Br J Pharmacol , vol.123 , pp. 1645-1654
    • Yoshimoto, R.1    Mitsui-Saito, M.2    Ozaki, H.3
  • 8
    • 0033038382 scopus 로고    scopus 로고
    • Role of nitric oxide-cGMP pathway in adrenomedullin-induced vasodilation in the rat
    • Hayakawa H, Hirata Y, Kakoki M, et al. Role of nitric oxide-cGMP pathway in adrenomedullin-induced vasodilation in the rat. Hypertension. 1999;33:689-93.
    • (1999) Hypertension , vol.33 , pp. 689-693
    • Hayakawa, H.1    Hirata, Y.2    Kakoki, M.3
  • 9
    • 0025952736 scopus 로고
    • Calcitonin gene-related peptide (CGRP)-induced cyclic AMP, cyclic GMP and vasorelaxant responses in rat thoracic aorta are antagonized by blockers of endothelium-derived relaxant factor (EDRF)
    • Fiscus R, Zhou HL, Wang X, et al. Calcitonin gene-related peptide (CGRP)-induced cyclic AMP, cyclic GMP and vasorelaxant responses in rat thoracic aorta are antagonized by blockers of endothelium-derived relaxant factor (EDRF). Neuropeptides. 1991;20:133-43.
    • (1991) Neuropeptides , vol.20 , pp. 133-143
    • Fiscus, R.1    Zhou, H.L.2    Wang, X.3
  • 10
    • 0026050630 scopus 로고
    • Calcitonin gene-related peptide (CGRP) causes endothelium-dependent cyclic AMP, cyclic GMP and vasorelaxant responses in rat abdominal aorta
    • Wang X, Han C, Fiscus RR. Calcitonin gene-related peptide (CGRP) causes endothelium-dependent cyclic AMP, cyclic GMP and vasorelaxant responses in rat abdominal aorta. Neuropeptides. 1991;20:115-24.
    • (1991) Neuropeptides , vol.20 , pp. 115-124
    • Wang, X.1    Han, C.2    Fiscus, R.R.3
  • 11
    • 0026803386 scopus 로고
    • Human α-calcitonin gene-related peptide stimulates adenylate cyclase and guanylate cyclase and relaxes rat thoracic aorta by releasing nitric oxide
    • Gray DW, Marshall I. Human α-calcitonin gene-related peptide stimulates adenylate cyclase and guanylate cyclase and relaxes rat thoracic aorta by releasing nitric oxide. Br J Pharmacol. 1992;107:691-6.
    • (1992) Br J Pharmacol , vol.107 , pp. 691-696
    • Gray, D.W.1    Marshall, I.2
  • 12
    • 0027954435 scopus 로고
    • Nitroglycerin (exogenous nitric oxide) substitutes for endothelium-derived nitric oxide in potentiating vasorelaxations and cyclic AMP elevations induced by calcitonin gene-related peptide (CGRP) in rat aorta
    • Fiscus RR, Hao H, Wang X, et al. Nitroglycerin (exogenous nitric oxide) substitutes for endothelium-derived nitric oxide in potentiating vasorelaxations and cyclic AMP elevations induced by calcitonin gene-related peptide (CGRP) in rat aorta. Neuropeptides. 1994;26:133-44.
    • (1994) Neuropeptides , vol.26 , pp. 133-144
    • Fiscus, R.R.1    Hao, H.2    Wang, X.3
  • 13
    • 0030781698 scopus 로고    scopus 로고
    • The antiproliferative effects of calcitonin gene-related peptide in different passages of cultured vascular smooth muscle cells
    • Li Y, Fiscus RR, Wu J, et al. The antiproliferative effects of calcitonin gene-related peptide in different passages of cultured vascular smooth muscle cells. Neuropeptide. 1997;31:503-9.
    • (1997) Neuropeptide , vol.31 , pp. 503-509
    • Li, Y.1    Fiscus, R.R.2    Wu, J.3
  • 14
    • 0032877780 scopus 로고    scopus 로고
    • Mechanism of SNAP potentiating antiproliferative effect of calcitonin gene-related peptide in cultured vascular smooth muscle cells
    • Wang X, Wang W, Li Y, et al. Mechanism of SNAP potentiating antiproliferative effect of calcitonin gene-related peptide in cultured vascular smooth muscle cells. J Mol Cell Cardiol. 1999;31:1599-606.
    • (1999) J Mol Cell Cardiol , vol.31 , pp. 1599-1606
    • Wang, X.1    Wang, W.2    Li, Y.3
  • 15
    • 0028922340 scopus 로고
    • Adrenomedullin stimulated two signal transduction pathways, cAMP accumulation and Ca2+ mobilization, in bovine aortic endothelial cells
    • Shimekake Y, Nagata K, Ohta S, et al. Adrenomedullin stimulated two signal transduction pathways, cAMP accumulation and Ca2+ mobilization, in bovine aortic endothelial cells. J Biol Chem. 1995;270:4412-7.
    • (1995) J Biol Chem , vol.270 , pp. 4412-4417
    • Shimekake, Y.1    Nagata, K.2    Ohta, S.3
  • 16
    • 0029822493 scopus 로고    scopus 로고
    • Diastolic dysfunction and natriuretic peptides in systolic heart failure: Higher ANP and BNP levels are associated with the restrictive filling pattern
    • Yu CM, Sanderson JE, Shum IO, et al. Diastolic dysfunction and natriuretic peptides in systolic heart failure: higher ANP and BNP levels are associated with the restrictive filling pattern. Eur Heart J. 1996;17:1694-702.
    • (1996) Eur Heart J , vol.17 , pp. 1694-1702
    • Yu, C.M.1    Sanderson, J.E.2    Shum, I.O.3
  • 17
    • 0024343491 scopus 로고
    • Brain natriuretic peptide (BNP) causes endothelium-independent relaxation and elevation of cyclic GMP in rat thoracic aorta
    • Zhou HL, Fiscus RR. Brain natriuretic peptide (BNP) causes endothelium-independent relaxation and elevation of cyclic GMP in rat thoracic aorta. Neuropeptides. 1989;14:161-9.
    • (1989) Neuropeptides , vol.14 , pp. 161-169
    • Zhou, H.L.1    Fiscus, R.R.2
  • 18
    • 0020980045 scopus 로고
    • Endothelium-dependent and nitrovasodilator-induced activation of cyclic GMP-dependent protein kinase in rat aorta
    • Fiscus RR, Rapoport RM, Murad F. Endothelium-dependent and nitrovasodilator-induced activation of cyclic GMP-dependent protein kinase in rat aorta. J Cycl Nucl Prot Phos Res. 1983;9:415-5.
    • (1983) J Cycl Nucl Prot Phos Res , vol.9 , pp. 415
    • Fiscus, R.R.1    Rapoport, R.M.2    Murad, F.3
  • 19
    • 0022261486 scopus 로고
    • Atriopeptin II elevates cyclic GMP, activates cyclic-GMP-dependent protein kinase and causes relaxation in rat thoracic aorta
    • Fiscus RR, Rapoport RM, Waldman SA, et al. Atriopeptin II elevates cyclic GMP, activates cyclic-GMP-dependent protein kinase and causes relaxation in rat thoracic aorta. Biochim Biophys Acta. 1985;846:179-184.
    • (1985) Biochim Biophys Acta , vol.846 , pp. 179-184
    • Fiscus, R.R.1    Rapoport, R.M.2    Waldman, S.A.3
  • 21
    • 0023701033 scopus 로고
    • Molecular mechanisms of endothelium-mediated vasodilation
    • Fiscus RR. Molecular mechanisms of endothelium-mediated vasodilation. Semin Thromb Hemost. 1988;14(suppl):12-22.
    • (1988) Semin Thromb Hemost , vol.14 , Issue.SUPPL. , pp. 12-22
    • Fiscus, R.R.1
  • 22
    • 0025644508 scopus 로고
    • Nitroprusside enhances isoprenaline-induced increases in cAMP in rat aortic smooth muscle
    • Maurice DH, Haslam RJ. Nitroprusside enhances isoprenaline-induced increases in cAMP in rat aortic smooth muscle, Eur J Pharmacol. 1990;191:471-5.
    • (1990) Eur J Pharmacol , vol.191 , pp. 471-475
    • Maurice, D.H.1    Haslam, R.J.2
  • 23
    • 0032435393 scopus 로고    scopus 로고
    • Brain natriuretic peptide enhances the endothelium-independent cAMP and vasorelaxant responses of calcitonin gene related peptide in rat aorta
    • Fiscus RR, Lu L, Tu AWK, et al. Brain natriuretic peptide enhances the endothelium-independent cAMP and vasorelaxant responses of calcitonin gene related peptide in rat aorta. Neuropeptides. 1998;32:499-509.
    • (1998) Neuropeptides , vol.32 , pp. 499-509
    • Fiscus, R.R.1    Lu, L.2    Tu, A.W.K.3
  • 24
    • 0025866974 scopus 로고
    • Selective inhibition of cGMP-inhibited and cGMP-noninhibited cyclic nucleotide phosphodiesterase and relaxation of rat aorta
    • Lindgren S, Rascon A, Andersson KE, et al. Selective inhibition of cGMP-inhibited and cGMP-noninhibited cyclic nucleotide phosphodiesterase and relaxation of rat aorta. Biochem Pharmacol. 1991;42:545-52.
    • (1991) Biochem Pharmacol , vol.42 , pp. 545-552
    • Lindgren, S.1    Rascon, A.2    Andersson, K.E.3
  • 25
    • 0033035734 scopus 로고    scopus 로고
    • Nitric oxide donors enhance calcitonin gene-related peptide-induced elevations of cyclic AMP in vascular smooth muscle cells
    • Lu LF, Fiscus RR. Nitric oxide donors enhance calcitonin gene-related peptide-induced elevations of cyclic AMP in vascular smooth muscle cells. Eur J Pharmacol, 1999;376:307-14.
    • (1999) Eur J Pharmacol , vol.376 , pp. 307-314
    • Lu, L.F.1    Fiscus, R.R.2
  • 26
    • 0035847606 scopus 로고    scopus 로고
    • Natriuretic peptides inhibit apoptosis and prolong the survival of serum-deprived PC 12 cells
    • Fiscus RR, Tu AWK, Cheng Chew SB. Natriuretic peptides inhibit apoptosis and prolong the survival of serum-deprived PC 12 cells. Neuroreport. 2001;12:185-9.
    • (2001) Neuroreport , vol.12 , pp. 185-189
    • Fiscus, R.R.1    Tu, A.W.K.2    Cheng Chew, S.B.3
  • 27
    • 0029834931 scopus 로고    scopus 로고
    • Superiority of brain natriuretic peptide as a hormonal marker of ventricular systolic and diastolic dysfunction and ventricular hypertrophy
    • Yamamoto K, Burnett JC, Jougasaki M, et al. Superiority of brain natriuretic peptide as a hormonal marker of ventricular systolic and diastolic dysfunction and ventricular hypertrophy. Hypertension. 1996;28:988-94.
    • (1996) Hypertension , vol.28 , pp. 988-994
    • Yamamoto, K.1    Burnett, J.C.2    Jougasaki, M.3
  • 28
    • 0029948712 scopus 로고    scopus 로고
    • Plasma brain natriuretic peptide as an indicator of left ventricular systolic function and long-term survival after acute myocardial infarction
    • Omland T, Aakvaag A, Bonarjee VV, et al. Plasma brain natriuretic peptide as an indicator of left ventricular systolic function and long-term survival after acute myocardial infarction. Circulation. 1996;93:1963-9.
    • (1996) Circulation , vol.93 , pp. 1963-1969
    • Omland, T.1    Aakvaag, A.2    Bonarjee, V.V.3
  • 29
    • 0032958260 scopus 로고    scopus 로고
    • Plasma adrenomedullin as an indicator of prognosis after acute myocardial infarction
    • Nagaya N, Nishikimi T, Uematsu M, et al. Plasma adrenomedullin as an indicator of prognosis after acute myocardial infarction. Heart. 1999;81:483-7.
    • (1999) Heart , vol.81 , pp. 483-487
    • Nagaya, N.1    Nishikimi, T.2    Uematsu, M.3
  • 30
    • 0034068128 scopus 로고    scopus 로고
    • Plasma adrenomedullin, a new independent predictor of prognosis in patients with chronic heart failure
    • Pousset F, Masson F, Chavirovskaia O, et al. Plasma adrenomedullin, a new independent predictor of prognosis in patients with chronic heart failure. Eur Heart J. 2000;21:1009-14.
    • (2000) Eur Heart J , vol.21 , pp. 1009-1014
    • Pousset, F.1    Masson, F.2    Chavirovskaia, O.3
  • 31
    • 0032765216 scopus 로고    scopus 로고
    • Bioactivity and interactions ofadrenomedullin and brain natriuretic peptide in patients with heart failure
    • Lainchbury JG, Nicholls MG, Espiner EA, et al. Bioactivity and interactions ofadrenomedullin and brain natriuretic peptide in patients with heart failure, Hypertension, 1999;34:70-5.
    • (1999) Hypertension , vol.34 , pp. 70-75
    • Lainchbury, J.G.1    Nicholls, M.G.2    Espiner, E.A.3
  • 32
    • 0034674021 scopus 로고    scopus 로고
    • Hypotension and resistance to lipopolysaccharide-induced shock in transgenic mice overexpressing adrenomedullin in their vasculature
    • Shindo T, Kurihara H, Maemura K, et al. Hypotension and resistance to lipopolysaccharide-induced shock in transgenic mice overexpressing adrenomedullin in their vasculature, Circulation. 2000;101:2309-16.
    • (2000) Circulation , vol.101 , pp. 2309-2316
    • Shindo, T.1    Kurihara, H.2    Maemura, K.3
  • 33
    • 0033011038 scopus 로고    scopus 로고
    • Vasopeptidase inhibition: A new concept in blood pressure management
    • Burnett JC. Vasopeptidase inhibition: a new concept in blood pressure management. J Hypertens Suppl. 1999;17:S37-43.
    • (1999) J Hypertens Suppl , vol.17
    • Burnett, J.C.1


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