The FRK/RAK-SHB signaling cascade: A versatile signal-transduction pathway that regulates cell survival, differentiation and proliferation

Current Molecular Medicine

Volumn 3, Issue 4, 2003, Pages 313-324

  Annerén, Cecilia ^a   Lindholm, Cecilla K ^b   Kriz, Vitezslav ^b   Welsh, Michael ^b  

^a HARVARD UNIVERSITY   (United States)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; AMYLASE; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR; FOCAL ADHESION KINASE; GLUCAGON; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; INTERLEUKIN 2 RECEPTOR; NERVE GROWTH FACTOR RECEPTOR; PHOSPHOSERINE; PHOSPHOTHREONINE; PHOSPHOTYROSINE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN FRK; PROTEIN SHB; PROTEIN TYROSINE KINASE; STRESS ACTIVATED PROTEIN KINASE; T LYMPHOCYTE RECEPTOR; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; CELL DEGENERATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CELL TYPE; CYTOKINE PRODUCTION; DNA FLANKING REGION; DRUG PROTEIN BINDING; EMBRYO CELL; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENE OVEREXPRESSION; HUMAN; LEUKEMIA CELL LINE; MITOGENICITY; MOLECULAR BIOLOGY; MORPHOGENESIS; NONHUMAN; PANCREAS ISLET CELL; PHEOCHROMOCYTOMA; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; RECEPTOR BINDING; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; STEM CELL; TUMOR SUPPRESSOR GENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARRIER PROTEINS; CELL DIFFERENTIATION; CELL DIVISION; CELL SURVIVAL; CELLS, CULTURED; COS CELLS; EMBRYO; FIBROBLASTS; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; JURKAT CELLS; MEMBRANE PROTEINS; MICE; MODELS, BIOLOGICAL; MODELS, GENETIC; NEOPLASM PROTEINS; NEURONS; PC12 CELLS; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RATS; RECEPTOR, TRKA; RECEPTORS, FIBROBLAST GROWTH FACTOR; RECEPTORS, INTERLEUKIN-2; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; SRC-FAMILY KINASES; TYROSINE;

EID: 0038443927     PISSN: 15665240     EISSN: None     Source Type: Journal    
DOI: 10.2174/1566524033479744     Document Type: Review

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