Effects of low concentrations of cadmium on immunoglobulin E production by human B lymphocytes in vitro

Toxicology

Volumn 188, Issue 1, 2003, Pages 35-48

  Jelovcan, Sandra ^a,b   Gutschi, Andrea ^a   Kleinhappl, Barbara ^a   Sedlmayr, Peter ^a   Barth, Sonja ^a   Marth, Egon ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b Inst Zool an Karl Franzens Univ   (Austria)

Author keywords

B cell activation; B lymphocyte; Cadmium; IgE synthesis; Immunotoxicity

Indexed keywords

CADMIUM; CD23 ANTIGEN; CD40 LIGAND MONOCLONAL ANTIBODY; CD69 ANTIGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 4;

ADULT; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; CELL ACTIVATION; CELL PROLIFERATION; CELL STIMULATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; HUMAN; HUMAN CELL; IMMUNOGLOBULIN PRODUCTION; IMMUNOMODULATION; IMMUNOREACTIVITY; IMMUNOSTIMULATION; IMMUNOTOXICITY; INHIBITION KINETICS; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0038394471     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(03)00044-1     Document Type: Article

References (48)

1. Bacharier L.B., Geha R.S. Molecular mechanisms of IgE regulation. J. Allergy Clin. Immunol. 105:2000;S547-S558.
2. Badou A., Savignac M., Moreau M., Leclerc C., Pasquier R., Druet P., Pelletier L. HgCl2-induced interleukin-4 gene expression in T cells involves a protein kinase C-dependent calcium influx through L-type calcium channels. J. Biol. Chem. 272:(51):1997;32411-32418.
3. Beyersmann D., Hechtenberg S. Cadmium, gene regulation, and cellular signalling in mammalian cells. Toxicol. Appl. Pharmacol. 144:1997;247-261.
4. Blakley B.R., Tomar R.S. The effect of cadmium on antibody responses to antigens with different cellular requirements. Int. J. Immunopharmacol. 8:(8):1986;1009-1015.
5. Block C., Freyermuth S., Beyersmann D., Malviya A.N. Role of cadmium in activating nuclear protein kinase C and the enzyme binding to nuclear protein. J. Biol. Chem. 267:(28):1992;19824-19828.
6. Bonnefoy J.-Y., Lecoanet-Henchoz S., Aubry J.-P., Gauchat J.-F., Graber P. CD23 and B-cell activation. Curr. Opin. Immunol. 7:1995;355-359.
7. Borella P., Giardino A. Lead and cadmium at very low doses affect in vitro immune response of human lymphocytes. Environ. Res. 55:1991;165-177.
8. Boyum A., Lovhaug D., Tresland L., Nordlie E.M. Separation of leucocytes: improved cell purity by fine adjustments of gradient medium density and osmolality. Scand. J. Immunol. 34:1991;697-712.
9. Campbell K.S. Signal transduction from the B cell antigen-receptor. Curr. Opin. Immunol. 11:1999;256-264.
10. Cifone M.G., Alesse E., Procopio A., Paolini R., Morrone S., Di Eugenio R., Santoni G., Santoni A. Effects of cadmium on lymphocyte activation. Biochim. Biophys. Acta. 1011:1989;25-32.
11. Daum J.R., Shepherd D.M., Noelle R.J. Immunotoxicology of cadmium and mercury on B-lymphocytes - I. Effects on lymphocyte function. Int. J. Immunopharmacol. 15:(3):1993;383-394.
12. Defrance T., Aubry J.P., Rousset F., Vanbervliet B., Bonnefoy J.Y., Arai N., Takebe Y., Yokota T., Lee F., Arai K., De Vires J., Banchereau J. Human recombinant interleukin 4 induces Fcε receptors (CD23) on normal human B lymphocytes. J. Exp. Med. 165:1987;1459-1467.
13. de Vries J.E., Gauchat J.-F., Aversa G.G., Punnonen J., Gascan H., Yssel H. Regulation of IgE synthesis by cytokines. Curr. Opin. Immunol. 3:1991;851-858.
14. Diaz-Sanchez D., Tsien A., Fleming J., Saxon A. Combined diesel exhaust particulate and ragweed allergen challenge markedly enhances human in vivo nasal ragweed-specific IgE and skews cytokine production to a T helper cell 2-type pattern. J. Immunol. 158:1997;2406-2413.
15. El Azzouzi B., Tsangaris G.T., Pellegrini O., Manuel Y., Benveniste J., Thomas Y. Cadmium induces apoptosis in a human T cell line. Toxicology. 88:1994;127-139.
16. Fujimaki H., Murakami M., Kubota K. In vitro evaluation of cadmium-induced augmentation of the antibody response. Toxicol. Appl. Pharmacol. 62:1982;288-293.
17. Fuleihan R., Ramesh N., Geha R.S. Role of CD40-CD40-ligand interaction in Ig-isotype switching. Curr. Opin. Immunol. 5:1993;963-967.
18. Funkhouser S.W., Martinez-Maza O., Vredevoe D.L. Cadmium inhibits IL-6 production and IL-6 mRNA expression in a human monocytic cell line, THP-1. Environ. Res. 66:1994;77-86.
19. Gardner P. Calcium and T lymphocyte activation. Cell. 59:1989;15-20.
20. Gascan H., Gauchat J.F., Aversa G., Van Vlasselaer P., de Vries J.E. Anti-CD40 monoclonal antibodies or CD4+ T cell clones and IL-4 induce IgG4 and IgE switching in purified human B cells via different signaling pathways. J. Immunol. 147:(1):1991;8-13.
21. Guo T.L., Mudzinski S.P., Lawrence D.A. Regulation of HLA-DR and invariant chain expression by human peripheral blood mononuclear cells with lead, interferon-γ, or interleukin-4. Cell. Immunol. 171:1996;1-9.
22. Horiguchi H., Mukaida N., Okamoto S.-I., Teranishi H., Kasuya M., Matsushima K. Cadmium induces interleukin-8 production in human peripheral blood mononuclear cells with the concomitant generation of superoxide radicals. Lymphokine Cytokine Res. 12:(6):1993;421-428.
23. Jabara H.H., Fu S.M., Geha R.S., Vercelli D. CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells. J. Exp. Med. 172:1990;1861-1864.
24. Jeannin P., Lecoanet-Henchoz S., Delneste Y., Gauchat J.F., Bonnefoy J.Y. Alpha-1 antitrypsin up-regulates human B cell differentiation selectively into IgE- and IgG4- secreting cells. Eur. J. Immunol. 28:(6):1998;1815-1822.
25. Jin P., Ringertz N.R. Cadmium induces transcription of proto-oncogenes c-jun and c-myc in rat L6 myoblasts. J. Biol. Chem. 265:(24):1990;14061-14064.
26. Karakaya A., Yücesoy B., Sardas O.S. An immunological study on workers occupationally exposed to cadmium. Hum. Exp. Toxicol. 13:1994;73-75.
27. Kayama F., Yoshida T., Elwell M.R., Luster M.I. Cadmium-induced renal damage and proinflammatory cytokines: possible role of IL-6 in tubular epithelial cell regeneration. Toxicol. Appl. Pharmacol. 134:1995;26-34.
28. Koller L.D., Exon J.H., Roan J.G. Humoral antibody response in mice after single dose exposure to lead or cadmium. Proc. Soc. Exp. Biol. Med. 151:1976;339-342.
29. Korzeniewsky C., Callewaert D.M. An enzyme-release assay for natural cytotoxicity. J. Immunol. Methods. 64:1983;313-320.
30. Lawrence D.A., McCabe M.J. Immune modulation by toxic metals. Goyer R.A., Klaassen C.D., Waalkes M.P. Metal Toxicology. 1995;305-337 Academic Press, San Diego, CA.
31. Lee C.-E., Yoon S.-R., Pyun K.-H. Interleukin-4 signals regulating CD23 gene expression in human B cells: protein kinase C-independent signaling pathways. Cell. Immunol. 146:1993;171-185.
32. Lundgren M., Persson U., Larsson P., Magnusson C., Smith C.I., Hammarstrom L., Severinson E. Interleukin 4 induces synthesis of IgE and IgG4 in human B cells. Eur. J. Immunol. 19:(7):1989;1311-1315.
33. Lutz P.M., Wilson T.J., Ireland J., Jones A.L., Gorman J.S., Gale N.L., Johnson J.C., Hewett J.E. Elevated immunoglobulin E (IgE) levels in children with exposure to environmental lead. Toxicology. 134:1999;63-78.
34. Martinotti S., Toniato E., Colagrande A., Alesse E., Alleva C., Screpanti I., Morrone S., Scarpa S., Frati L., Hayday A.C., Piovella F., Gulino A. Heavy-metal modulation of the human intercellular adhesion molecule (ICAM-1) gene expression. Biochim. Biophys. Acta. 1261:1995;107-114.
35. Ritz B., Heinrich J., Wjst M., Wichmann E., Krause C. Effect of cadmium body burden on immune response of school children. Arch. Environ. Health. 53:(4):1998;272-280.
36. Saeland S., Duvert V., Moreau I., Banchereau J. Human B cell precursors proliferate and express CD23 after CD40 ligation. J. Exp. Med. 178:1993;113-120.
37. Sarasua S.M. Serum immunoglobulins and lymphocyte subset distributions in children and adults living in communities assessed for lead and cadmium exposure. J. Toxicol. Environ. Health A. 60:2000;1-15.
38. Schulte S., Mengel K., Gätke U., Friedberg K.D. No influence of cadmium on the production of specific antibodies in mice. Toxicology. 93:1994;263-268.
39. Shen H.-M., Dong S.-Y., Ong C.-N. Critical role of calcium overloading in cadmium-induced apoptosis in mouse thymocytes. Toxicol. Appl. Pharmacol. 171:2001;12-19. doi:10.1006/taap.2000.9092.
40. Smith J.B., Dwyer S.D., Smith L. Cadmium evokes inositol polyphosphate formation and calcium mobilization. J. Biol. Chem. 264:(13):1989;7115-7118.
41. Steffensen I.-L., Mesna O.J., Andruchow E., Namork E., Hylland K., Andersen R.A. Cytotoxicity and accumulation of Hg, Ag, Cd, Cu, Pb and Zn in human peripheral T and B lymphocytes and monocytes in vitro. Gen. Pharmacol. 25:(8):1994;1621-1633.
42. Takenaka H., Zhang K., Diaz-Sanchez D., Tsien A., Saxon A. Enhanced human IgE production results from exposure to the aromatic hydrocarbons from diesel exhaust: direct effects on B-cell IgE production. J. Allergy Clin. Immunol. 95:1995;103-115.
43. Testi R., D'Ambrosio D., De Maria R., Santoni A. The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells. Immunol. Today. 15:(10):1994;479-483.
44. Theocharis S.E., Souliotis V.L., Panayiotidis P.G. Suppression of interleukin-1β and tumour necrosis factor-α biosynthesis by cadmium in in vitro activated human peripheral blood mononuclear cells. Arch. Toxicol. 69:1994;132-136.
45. Tsangaris G.T., Tzortzatou-Stathopoulou F. Cadmium induces apoptosis differentially on immune system cell lines. Toxicology. 128:1998;143-150.
46. Turner K.J., Holt P.G., Holt B.J., Cameron K.J. In vitro synthesis of IgE by human peripheral blood leucocytes. III. Release of pre-formed antibody. Clin. Exp. Immunol. 51:1983;387-394.
47. Worm M., Henz B.M. Molecular regulation of human IgE synthesis. J. Mol. Med. 75:1997;440-447.
48. Zhang K., Clark E.A., Saxon A. CD40 stimulation provides an IFN-γ-independent and IL-4-dependent differentiation signal directly to human B cells for IgE production. J. Immunol. 146:(6):1991;1836-1842.