An efficient method for the regioselective aminolysis of 2,3α-steroidal epoxide

Synlett

Volumn , Issue 8, 2003, Pages 1192-1194

  Thibeault, Dominic ^a   Poirier, Donald ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Amines; Amino alcohols; Epoxides; Lanthanides; Steroids

Indexed keywords

2,3ALPHA STEROIDAL EPOXIDE; AMINE; AMINOALCOHOL; EPOXIDE; LANTHANIDE; STEROID; UNCLASSIFIED DRUG;

AMINOLYSIS; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; TEMPERATURE;

EID: 0038391433     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-39901     Document Type: Article

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42. The relative configuration of the 2β-aminosteroids given in Table 1 was confirmed by X-ray crystallographic examination of a representative compound. A comparison of the NMR spectroscopic data allowed the assignment of the 2β-amino-3α-hydroxy configuration in the other compounds.