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Note that nonviral gene delivery techniques based electrostatic interactions have recently been developed: Polyethylenimine, a cationic polymer, has been shown to form nontoxic complexes with (anionic) DNA molecules that spontaneously enter the cells. See for instance O. Boussif, F. Lezoualc'h, M. A. Zanta, M. D. Mergny, D. Scherman, B. Demeneix, and J.P. Behr, Proc. Natl. Acad. Sci. U.S.A. 92, 7297 (1995).
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edited by W. M. Gelbart, A. Ben-Shaul, and D. Roux (Springer, New York)
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The precise value for A is still matter of debate. See H. Kleinert, Phys. Lett. A 257, 269 (1999), and references therein.
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It can be shown that in the absence of surface tension, no energy barrier is involved for the transition between the bound state and the fully wrapped state. See M. Deserno and T. Bickel, Preprint cond-mat/0212421.
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The term "proximal" has been introduced by de Gennes in the context of polymer adsorption, in order to describe the particular region where the microscopic details of the surface are relevant (Ref. 42). Here however, we use this term with the general meaning of proximity.
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52
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0038060198
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note
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Although the density is certainly nonzero for slightly negative values of z, the profiles are known only for z ≥ 0. This restriction is actually inherent to the perturbative scheme followed in this work. Note, however, that the correction to the Gibbs adsorbance takes into account the amount of chains located at z <0.
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53
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0038398555
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note
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See, for instance, Eqs. (1)-(3) in Ref. 17.
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