Mutants suppressing novobiocin hypersensitivity of a mukB null mutation

Journal of Bacteriology

Volumn 185, Issue 13, 2003, Pages 3690-3695

  Adachi, Shun ^a   Hiraga, Sota ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); GYRASE INHIBITOR; NOVOBIOCIN;

AMINO ACID SUBSTITUTION; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIUM ISOLATION; BACTERIUM MUTANT; BETA CHAIN; CHROMOSOME SEGREGATION; CONTROLLED STUDY; ESCHERICHIA COLI; MUKB GENE; NONHUMAN; PRIORITY JOURNAL; SISTER CHROMATID; TURBIDITY; X IRRADIATION;

BACTERIAL PROTEINS; CHROMOSOMAL PROTEINS, NON-HISTONE; CHROMOSOMES, BACTERIAL; DNA GYRASE; DRUG RESISTANCE, BACTERIAL; ENZYME INHIBITORS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; MICROBIAL SENSITIVITY TESTS; MUTATION; NOVOBIOCIN; SUPPRESSION, GENETIC; X-RAYS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0038377586     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.185.13.3690-3695.2003     Document Type: Article

References (23)

1. Ali, J. A., A. P. Lackson, A. J. Howells, and A. Maxwell. 1993. The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs. Biochemistry 32:2717-2724.
2. Friedherg, E. C., G. C. Walker, and W. Siede. 1995. DNA repair and mutagenesis. ASM Press, Washington, D.C.
3. Gellert, M., M. H. O'Dea, T. Itoh, and J. Tomozawa. 1976. Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase. Proc. Natl. Acad. Sci. USA 73:4474-4478.
4. Hiraga, S. 2000. Dynamic localization of bacterial and plasmid chromosomes. Annu. Rev. Genet. 34:21-59.
5. Hiraga, S., H. Niki, T. Ogura, C. Ichinose, H. Moll, B. Ezaki, and A. Jaffé. 1989. Chromosome partitioning in Escherichia coli: novel mutants producing anucleate cells. J. Bacteriol. 171:1496-1505.
6. Hiraga, S., C. Ichinose, T. Onogi, H. Niki, and M. Yamazoe. 2000. Bidirectional migration of SeqA-bound hemimethylated DNA clusters and pairing of oriC copies in Escherichia coli. Genes Cells 5:327-341.
7. Lewis, R. J., O. M. P. Singh, C. V. Smith, T. Skarzynski, A. Maxwell, A. J. Wonacott, and D. B. Wigley. 1996. The nature of inhibition of DNA gyrase by the coumarins and the cyclothialidines revealed by X-ray crystallography. EMBO J. 15:1412-1420.
8. Li, Y., K. Sergueev, and S. Austin. 2002. The segregation of the Escherichia coli origin and terminus of replication. Mol. Microbiol. 46:985-995.
9. Melby, T. E., C. N. Ciampaglio, G. Briscore, and H. P. Erickson. 1998. The symmetrical structure maintenance of chromosomes (SMC) and MukB proteins: long, antiparallel coiled coils, folded at a flexible hinge. J. Cell Biol. 142:1595-1604.
10. Niki, H., R. Imamura, M. Kitaoka, K. Yamanaka, T. Ogura, and S. Hiraga. 1992. E. coli MukB protein involved in chromosome partition forms a homodimer with a rod-and-hinge structure having DNA binding and ATP/GTP binding activities. EMBO J. 11:5101-5109.
11. Niki, H., A. Jaffé, R. Imamura, T. Ogura, and S. Hiraga. 1991. The new gene mukB codes for a 177 kd protein with coiled-coil domains involved in chromosome partitioning of E. coli. EMBO J. 10:183-193.
12. Ohsumi, K., M. Yamazoe, and S. Hiraga. 2001. Different localization of SeqA-bound nasceni DNA clusters and MukF-MukE-MukB complex in Escherichia coli cells. Mol. Mirobiol. 40;835-845.
13. Onogi, T., K. Ohsumi, T. Katayama, and S. Hiraga. 2002. Replication-dependent recruitment of the β-subunit of DNA polymerase III from cytosolic spaces to replication forks in Escherichia coli. J. Bacteriol. 184:867-870.
14. Onogi, T., M. Yamazoe, C. Ichinose, H. Niki, and S. Hiraga. 2000. Null mutation of the dam or seqA gene suppresses temperature-sensitive lethality but not hypersensitivity to novobiocin of muk null mutants. J. Bacteriol. 182:5898-5901.
15. Ream, L. W., L. Margossian, and J. C. Alvin. 1980. Genetic and physical mapping of recF in Escherichia coli K-12. Mol. Gen. Genet. 180:115-121.
16. Sawitzke, J. A., and S. Austin. 2000. Suppression of chromosome segregation defects of Escherichia coli muk mutants by mutations in topoisomerase I. Proc. Natl. Acad. Sci. USA 97:1671-1676.
17. Sugino, A., C. L. Peehles, K. N. K. Kreuzer, and N. R. Cozzarelli. 1977. Mechanism of action of nalidixic acid: purification of Escherichia coli naIA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme. Proc. Natl. Acad. Sci. USA 74:4767-4771.
18. Sunako, Y., T. Onogi, and S. Hiraga. 2001. Sister chromosome cohesion of Escherichia coli. Mol. Microbiol. 42:1233-1241.
19. Weilao, T., S. Dasgupta, and K. Nordström. 2000. Role of the mukB gene in chromosome and plasmid partition in Escherichia coli. Mol. Microbiol. 38:392-400.
20. Weitao, T., K. Nordström, and S. Dasgupta. 1999. Mutual suppression of mukB and seqA phenotypes might arise from their opposing influences on the Escherichia coli nucleoid structure. Mol. Microbiol. 34:157-168.
21. Weitao, T., K. Nordström, and S. Dasgupta. 2000. Escherichia coli cell cycle control genes affect chromosome superhelicity. EMBO Rep. 1:494-499.
22. Yamanaka, K., T. Ogura, H. Niki, and S. Hiraga. 1996. Identification of two new genes, mukE and mukF, involved in chromosome partitioning in Escherichia coli. Mol. Gen. Genet. 250:241-251.
23. Yamazoe, M., T. Onogi, Y. Sunako, H. Niki, K. Yamanaka, T. Ichimura, and S. Hiraga. 1999. Complex formation of MukB, MukE and MukF proteins involved in chromosome partitioning in Escherichia coli. EMBO J. 18:5873-5884.