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Volumn 114, Issue 1, 2003, Pages 65-72

Phosphorylation of the α4 subunit of human α4β2 nicotinic receptors: Role of cAMP-dependent protein kinase (PKA) and protein kinase C (PKC)

Author keywords

Cyclic AMP dependent protein kinase; Human 4 2 neuronal nicotinic receptors; Phosphorylation; Protein kinase C

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; ADENOSINE TRIPHOSPHATE; BUCLADESINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DERIVATIVE; FORSKOLIN; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NICOTINIC RECEPTOR; PHOSPHATE; PROTEIN KINASE C; PROTEIN SUBUNIT; 8 BROMO CYCLIC AMP; 8 BROMOADENOSINE 3',5' CYCLIC MONOPHOSPHOROTHIOATE; 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE; CARCINOGEN; DRUG DERIVATIVE; ENZYME INHIBITOR; INDOLE DERIVATIVE; ISOQUINOLINE DERIVATIVE; NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA4 SUBUNIT; NICOTINIC RECEPTOR ALPHA4BETA2; NUCLEOTIDE; PHORBOL 13 ACETATE 12 MYRISTATE; RO 31-8220; SULFONAMIDE;

EID: 0038356890     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(03)00138-4     Document Type: Article
Times cited : (17)

References (29)
  • 1
    • 0033579464 scopus 로고    scopus 로고
    • Sequence- and structure-based prediction of eukaryotic protein phosphorylation sites
    • Blom N., Gammeltoft S., Brunak S. Sequence- and structure-based prediction of eukaryotic protein phosphorylation sites. J. Mol. Biol. 294:1999;1351-1362.
    • (1999) J. Mol. Biol. , vol.294 , pp. 1351-1362
    • Blom, N.1    Gammeltoft, S.2    Brunak, S.3
  • 2
    • 0035869342 scopus 로고    scopus 로고
    • Chronic exposure to nicotine upregulates the human α4β2 nicotinic acetylcholine receptor function
    • Buisson B., Bertrand D. Chronic exposure to nicotine upregulates the human α4β2 nicotinic acetylcholine receptor function. J. Neurosci. 21:2001;1819-1829.
    • (2001) J. Neurosci. , vol.21 , pp. 1819-1829
    • Buisson, B.1    Bertrand, D.2
  • 3
    • 0034001046 scopus 로고    scopus 로고
    • Multiple components in the agonist concentration-response relationships of neuronal nicotinic acetylcholine receptors
    • Covernton P.J., Connolly J.G. Multiple components in the agonist concentration-response relationships of neuronal nicotinic acetylcholine receptors. J. Neurosci. Methods. 96:2000;63-70.
    • (2000) J. Neurosci. Methods , vol.96 , pp. 63-70
    • Covernton, P.J.1    Connolly, J.G.2
  • 5
    • 0031466434 scopus 로고    scopus 로고
    • Functional deactivation of the major neuronal nicotinic receptor caused by nicotine and a protein kinase C-dependent mechanism
    • Eilers H., Schaeffer E., Bickler P.E., Forsayeth J.R. Functional deactivation of the major neuronal nicotinic receptor caused by nicotine and a protein kinase C-dependent mechanism. Mol. Pharmacol. 52:1997;1105-1112.
    • (1997) Mol. Pharmacol. , vol.52 , pp. 1105-1112
    • Eilers, H.1    Schaeffer, E.2    Bickler, P.E.3    Forsayeth, J.R.4
  • 7
    • 0037215547 scopus 로고    scopus 로고
    • Effects of prolonged nicotinic ligand exposure on function of heterologously expressed human α4β2- and α4β4-nicotinic acetylcholine receptors
    • Gentry C.L., Wilkins L.H. Jr., Lukas R.J. Effects of prolonged nicotinic ligand exposure on function of heterologously expressed human α4β2- and α4β4-nicotinic acetylcholine receptors. J. Pharmacol. Exp. Ther. 304:2003;206-216.
    • (2003) J. Pharmacol. Exp. Ther. , vol.304 , pp. 206-216
    • Gentry, C.L.1    Wilkins L.H., Jr.2    Lukas, R.J.3
  • 8
    • 0030610921 scopus 로고    scopus 로고
    • Regulation of human α4β2 neuronal nicotinic acetylcholine receptors by cholinergic channel ligands and second messenger pathways
    • Gopalakrishnan M., Molinari E.J., Sullivan J.P. Regulation of human α4β2 neuronal nicotinic acetylcholine receptors by cholinergic channel ligands and second messenger pathways. Mol. Pharmacol. 52:1997;524-534.
    • (1997) Mol. Pharmacol. , vol.52 , pp. 524-534
    • Gopalakrishnan, M.1    Molinari, E.J.2    Sullivan, J.P.3
  • 9
    • 0036068573 scopus 로고    scopus 로고
    • Identification of three cAMP-dependent protein kinase (PKA) phosphorylation sites within the major intracellular domain of neuronal nicotinic receptor α4 subunits
    • Guo X., Wecker L. Identification of three cAMP-dependent protein kinase (PKA) phosphorylation sites within the major intracellular domain of neuronal nicotinic receptor α4 subunits. J. Neurochem. 82:2002;439-447.
    • (2002) J. Neurochem. , vol.82 , pp. 439-447
    • Guo, X.1    Wecker, L.2
  • 10
    • 0030068020 scopus 로고    scopus 로고
    • Sustained nicotine exposure differentially affects α3β2 and α4β2 neuronal nicotinic receptors expressed in Xenopus oocytes
    • Hsu Y.-N., Amin J., Weiss D.S., Wecker L. Sustained nicotine exposure differentially affects α3β2 and α4β2 neuronal nicotinic receptors expressed in Xenopus oocytes. J. Neurochem. 66:1996;667-675.
    • (1996) J. Neurochem. , vol.66 , pp. 667-675
    • Hsu, Y.-N.1    Amin, J.2    Weiss, D.S.3    Wecker, L.4
  • 11
    • 0030722148 scopus 로고    scopus 로고
    • Nicotine enhances the cyclic AMP-dependent protein kinase-mediated phosphorylation of α4 subunits of neuronal nicotinic receptors
    • Hsu Y.-N., Edwards S.C., Wecker L. Nicotine enhances the cyclic AMP-dependent protein kinase-mediated phosphorylation of α4 subunits of neuronal nicotinic receptors. J. Neurochem. 69:1997;2427-2431.
    • (1997) J. Neurochem. , vol.69 , pp. 2427-2431
    • Hsu, Y.-N.1    Edwards, S.C.2    Wecker, L.3
  • 12
    • 0035958852 scopus 로고    scopus 로고
    • The chaperone protein 14-3-3η interacts with the nicotinic acetylcholine receptor α4 subunit
    • Jeanclos E.M., Lin L., Treuil M.W., Rao J., DeCoster M.A., Anand R. The chaperone protein 14-3-3η interacts with the nicotinic acetylcholine receptor α4 subunit. J. Biol. Chem. 276:2001;28281-28290.
    • (2001) J. Biol. Chem. , vol.276 , pp. 28281-28290
    • Jeanclos, E.M.1    Lin, L.2    Treuil, M.W.3    Rao, J.4    DeCoster, M.A.5    Anand, R.6
  • 13
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 15
    • 0032616958 scopus 로고    scopus 로고
    • Modulation of ion channels by protein phosphorylation - How the brain works
    • Levitan I.B. Modulation of ion channels by protein phosphorylation - how the brain works. Adv. Second Messenger Phosphoprotein Res. 33:1999;3-22.
    • (1999) Adv. Second Messenger Phosphoprotein Res. , vol.33 , pp. 3-22
    • Levitan, I.B.1
  • 16
    • 0011631320 scopus 로고
    • Regulation of nicotinic acetylcholine receptor phosphorylation in rat myotubes by forskolin and cAMP
    • Miles K., Anthony D.T., Rubin L.L., Greengard P., Huganir R.L. Regulation of nicotinic acetylcholine receptor phosphorylation in rat myotubes by forskolin and cAMP. Proc. Natl. Acad. Sci. 84:1987;6591-6595.
    • (1987) Proc. Natl. Acad. Sci. , vol.84 , pp. 6591-6595
    • Miles, K.1    Anthony, D.T.2    Rubin, L.L.3    Greengard, P.4    Huganir, R.L.5
  • 17
    • 0027304248 scopus 로고
    • Phosphorylation of rat brain nicotinic acetylcholine receptor by cAMP-dependent protein kinase in vitro
    • Nakayama H., Okuda H., Nakashima T. Phosphorylation of rat brain nicotinic acetylcholine receptor by cAMP-dependent protein kinase in vitro. Mol. Brain Res. 20:1993;171-177.
    • (1993) Mol. Brain Res. , vol.20 , pp. 171-177
    • Nakayama, H.1    Okuda, H.2    Nakashima, T.3
  • 18
    • 0027818140 scopus 로고
    • In vitro phosphorylation of rat brain nicotinic acetylcholine receptor by cAMP-dependent protein kinase
    • Nakayama H., Okuda H., Nakashima T. In vitro phosphorylation of rat brain nicotinic acetylcholine receptor by cAMP-dependent protein kinase. Ann. N. Y. Acad. Sci. 707:1993;439-442.
    • (1993) Ann. N. Y. Acad. Sci. , vol.707 , pp. 439-442
    • Nakayama, H.1    Okuda, H.2    Nakashima, T.3
  • 19
    • 0032988987 scopus 로고    scopus 로고
    • H-series protein kinase inhibitors and potential clinical applications
    • Ono-Saito N., Niki I., Hidaka H. H-series protein kinase inhibitors and potential clinical applications. Pharmacol. Ther. 82:1999;123-131.
    • (1999) Pharmacol. Ther. , vol.82 , pp. 123-131
    • Ono-Saito, N.1    Niki, I.2    Hidaka, H.3
  • 20
    • 0034741982 scopus 로고    scopus 로고
    • Characterization of human α4β2 neuronal nicotinic receptors stably transfected in SH-EP1 cells
    • Pacheco M.A., Pastoor T.E., Lukas R.J., Wecker L. Characterization of human α4β2 neuronal nicotinic receptors stably transfected in SH-EP1 cells. Neurochem. Res. 26:2001;683-693.
    • (2001) Neurochem. Res. , vol.26 , pp. 683-693
    • Pacheco, M.A.1    Pastoor, T.E.2    Lukas, R.J.3    Wecker, L.4
  • 21
    • 0031915461 scopus 로고    scopus 로고
    • Phosphorylation and regulation of antidepressant-sensitive serotonin transporters
    • Ramamoorthy S., Giovanetti E., Qian Y., Blakely R.D. Phosphorylation and regulation of antidepressant-sensitive serotonin transporters. J. Biol. Chem. 273:1998;2458-2466.
    • (1998) J. Biol. Chem. , vol.273 , pp. 2458-2466
    • Ramamoorthy, S.1    Giovanetti, E.2    Qian, Y.3    Blakely, R.D.4
  • 22
    • 0030034224 scopus 로고    scopus 로고
    • Post-translational regulation of neuronal acetylcholine receptors stably expressed in a mouse fibroblast cell line
    • Rothhut B., Romano S.J., Vijayaraghavan S., Berg D.K. Post-translational regulation of neuronal acetylcholine receptors stably expressed in a mouse fibroblast cell line. J. Neurobiol. 29:1996;115-125.
    • (1996) J. Neurobiol. , vol.29 , pp. 115-125
    • Rothhut, B.1    Romano, S.J.2    Vijayaraghavan, S.3    Berg, D.K.4
  • 23
    • 0027942378 scopus 로고
    • Membrane-permeant derivatives of cyclic AMP optimized for high potency, prolonged activity, or rapid reversibility
    • Schultz C., Vajanaphanich M., Genieser H.-G., Jastorff B., Barrett K.E., Tsien R.Y. Membrane-permeant derivatives of cyclic AMP optimized for high potency, prolonged activity, or rapid reversibility. Mol. Pharmacol. 46:1994;702-708.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 702-708
    • Schultz, C.1    Vajanaphanich, M.2    Genieser, H.-G.3    Jastorff, B.4    Barrett, K.E.5    Tsien, R.Y.6
  • 25
    • 0036479325 scopus 로고    scopus 로고
    • 14-3-3 proteins: Active cofactors in cellular regulation by serine/threonine phosphorylation
    • Tzivion G., Avruch J. 14-3-3 proteins: active cofactors in cellular regulation by serine/threonine phosphorylation. J. Biol. Chem. 277:2002;3061-3064.
    • (2002) J. Biol. Chem. , vol.277 , pp. 3061-3064
    • Tzivion, G.1    Avruch, J.2
  • 26
    • 0025499657 scopus 로고
    • Cyclic AMP-dependent phosphorylation of a neuronal acetylcholine receptor α-type subunit
    • Vijayaraghavan S., Schmid H.A., Halvorsen S.W., Berg D.K. Cyclic AMP-dependent phosphorylation of a neuronal acetylcholine receptor α-type subunit. J. Neurosci. 10:1990;3255-3262.
    • (1990) J. Neurosci. , vol.10 , pp. 3255-3262
    • Vijayaraghavan, S.1    Schmid, H.A.2    Halvorsen, S.W.3    Berg, D.K.4
  • 27
    • 0032528973 scopus 로고    scopus 로고
    • The α4 subunit of rat α4β2 nicotinic receptors is phosphorylated in vivo
    • Viseshakul N., Figl A., Lytle C., Cohen B.N. The α4 subunit of rat α4β2 nicotinic receptors is phosphorylated in vivo. Mol. Brain Res. 59:1998;100-104.
    • (1998) Mol. Brain Res. , vol.59 , pp. 100-104
    • Viseshakul, N.1    Figl, A.2    Lytle, C.3    Cohen, B.N.4
  • 28
    • 0035150853 scopus 로고    scopus 로고
    • Cyclic AMP-dependent protein kinase A (PKA) and protein kinase C phosphorylate sites in the amino acid sequence corresponding to the M3/M4 cytoplasmic domain of α4 neuronal nicotinic receptor subunits
    • Wecker L., Guo X., Rycerz A.M., Edwards S.C. Cyclic AMP-dependent protein kinase A (PKA) and protein kinase C phosphorylate sites in the amino acid sequence corresponding to the M3/M4 cytoplasmic domain of α4 neuronal nicotinic receptor subunits. J. Neurochem. 76:2001;711-720.
    • (2001) J. Neurochem. , vol.76 , pp. 711-720
    • Wecker, L.1    Guo, X.2    Rycerz, A.M.3    Edwards, S.C.4
  • 29
    • 0037375682 scopus 로고    scopus 로고
    • Phosphorylation sites within α4 subunits of α4β2 neuronal nicotinic receptors: A comparison of substrate specificities for cAMP-dependent protein kinase (PKA) and protein kinase C (PKC)
    • Wecker L., Rogers C.Q. Phosphorylation sites within α4 subunits of α4β2 neuronal nicotinic receptors: a comparison of substrate specificities for cAMP-dependent protein kinase (PKA) and protein kinase C (PKC). Neurochem. Res. 28:2003;431-436.
    • (2003) Neurochem. Res. , vol.28 , pp. 431-436
    • Wecker, L.1    Rogers, C.Q.2


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