1,4-benzothiazine analogues and apoptosis: Structure-activity relationship

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 15, 2003, Pages 3245-3254

  Fringuelli, Renata ^a   Schiaffella, Fausto ^a   Navarro, M Pilar Utrilla ^a,b   Milanese, Lara ^a   Santini, Cristina ^a   Rapucci, Michela ^a   Marchetti, Cristina ^a   Riccardi, Carlo ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF GRANADA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 6 [2 (4 METHYLPIPERAZINYL)ACETYL] 1,2,3,4 TETRAHYDROQUINOLIN 2 ONE; 1,4 BENZOTHIAZINE; 1,4-BENZOTHIAZINE; 4 METHYL 6 [2 (3 METHYLPIPERAZINYL)ACETYL] 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; 4 METHYL 6 [2 (4 METHYLPIPERAZINYL)ACETYL] 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; 6 [1 HYDROXY 2 (1H 1 IMIDAZOLYL)ETHYL] 1 METHYL 1,2,3,4 TETRAHYDROQUINOLIN 2 ONE; 6 [1 HYDROXY 2 (1H 1 IMIDAZOLYL)ETHYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; 6 [1 HYDROXY 2 (1H 1 IMIDAZOLYL)ETHYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOXAZIN 3 ONE; 6 [1 HYDROXY 2 (3 METHYLPIPERAZINYL)ETHYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; 6 [1 HYDROXY 2 (4 METHYLPIPERAZINYL)ETHYL] 1 METHYL 1,2,3,4 TETRAHYDROQUINOLIN 2 ONE; 6 [1 HYDROXY 2 (4 METHYLPIPERAZINYL)ETHYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; 6 [1 HYDROXY 2 [4 (2 METHOXYPHENYL)PIPERAZINYL]ETHYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; 6 [1 [(4 CHLOROBENZYL)OXY] 2 (1H 1 BENZ[D]IMIDAZOLYL)ETHYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; 6 [1 [(4 CHLOROBENZYL)OXY] 2 (1H 1 IMIDAZOLYL)ETHYL] 1 METHYL 1,2,3,4 TETRAHYDROQUINOLIN 2 ONE; 6 [1 [(4 CHLOROBENZYL)OXY] 2 (1H 1 IMIDAZOLYL)ETHYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; 6 [1 [(4 CHLOROBENZYL)OXY] 2 (1H 1 IMIDAZOLYL)ETHYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOXAZIN 3 ONE; 6 [1 [(4 CHLOROBENZYL)OXY] 2 (3 METHYLPIPERAZINYL)ETHYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; 6 [1 [(4 CHLOROBENZYL)OXY] 2 (4 METHYLPIPERAZINYL)ETHYL] 1 METHYL 1,2,3,4 TETRAHYDROQUINOLIN 2 ONE; 6 [1 [(4 CHLOROBENZYL)OXY] 2 (4 METHYLPIPERAZINYL)ETHYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; 6 [1 [(4 CHLOROBENZYL)OXY] 2 (4 METHYLPIPERAZINYL)ETHYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOXAZIN 3 ONE; 6 [1 [(4 CHLOROBENZYL)OXY] 2 [4 (2 METHOXYPHENYL)PIPERAZINYL]ETHYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; 6 [2 (1H 1 BENZ[D]IMIDAZOLYL)ACETYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; 6 [2 (1H 1 IMIDAZOLYL) 1 ETHENYL] 1 METHYL 1,2,3,4 TETRAHYDROQUINOLIN 2 ONE; 6 [2 (1H 1 IMIDAZOLYL) 1 ETHYNYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; 6 [2 (1H 1 IMIDAZOLYL) 1 ETHYNYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOXAZIN 3 ONE; 6 [2 (1H 1 IMIDAZOLYL)ACETYL] 1 METHYL 1,2,3,4 TETRAHYDROQUINOLIN 2 ONE; 6 [2 (1H 1 IMIDAZOLYL)ACETYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; 6 [2 (1H 1 IMIDAZOLYL)ACETYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOXAZIN 3 ONE; 6 [2 [4 (2 METHOXYPHENYL)PIPERAZINYL]ACETYL] 4 METHYL 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 3 ONE; BENZOTHIAZINE DERIVATIVE; THIAZINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CHEMISTRY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOLOGY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; MOUSE; MOUSE STRAIN; NONHUMAN; PHYSIOLOGY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; THYMOCYTE; THYMUS;

EID: 0038354630     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(03)00296-7     Document Type: Article

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