Age differences in allostatic load: An index of physiological dysregulation

Experimental Gerontology

Volumn 38, Issue 7, 2003, Pages 731-734

  Crimmins, Eileen M ^a   Johnston, Melanie ^a   Hayward, Mark ^b   Seeman, Teresa ^c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Allostatic load; National Health and Nutrition Examination Survey; Physiologic dysregulation

Indexed keywords

ADULT; AGE; AGED; CONFERENCE PAPER; CONTROLLED STUDY; HEALTH STATUS; HUMAN; HYPOTHESIS; MAJOR CLINICAL STUDY; MORTALITY; PHYSIOLOGY; POPULATION; PRIORITY JOURNAL; UNITED STATES;

EID: 0038349408     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(03)00099-8     Document Type: Conference Paper

References (13)

1. Crimmins E. Mortality and human life spans. Exp. Gerontol. 36:2001;885-897.
2. Kannisto V. Frailty and survival. Genus. 47:1991;101-118.
3. Lakka H.M., Laaksonen D.E., Lakka T.A., Niskanen L.K., Kumpusalo E., Tuomilehto J., Salonen J.T. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA. 288:(21):2002;2709-2716.
4. Lipsitz L.A., Goldberger A.L. Loss of complexity of aging: potential applications to fractals and chaos theory to senescence. JAMA. 267:1992;1806-1809.
5. Manton K., Woodbury M., Stallard E. Sex differences in human mortaltiy and aging at the late ages: the effect of mortality selection and state dynamics. Gerontologist. 35:1995;597-608.
6. McEwen B.S., Stellar E. Stress and the individual: mechanisms leading to disease. Arch. Intern. Med. 153:1993;2093-2101.
7. McEwen B.S. Protective and damaging effects of stress mediators. N Engl. J. Med. 338:(3):1998;171-179.
8. Vital and Health Statistics, Series 1, No. 32. Vital and Health Statistics, Series 1, No. 32. 1994.
9. Seeman T.E., Singer B.H., Rowe J.W., Horwitz R.I., McEwen B.S. The price of adaptation - allostatic load and its health consequences: MacArthur studies of successful aging. Arch. Intern. Med. 157:1997;2259-2268.
10. Seeman T.E., McEwen B.S., Rowe J.W., Singer B.H. Allostatic load as a marker of cumulative biological risk: MacArthur studies of successful aging. Proc. Nat Acad. Sci. USA. 98:(8):2001;4770-4775.
11. Singer B., Ryff C. Hierarchies of life histories. Ann. N Y Acad. Sci. 896:1999;96-115.
12. Sterling P., Eyer J. Allostasis: a new paradigm to explain arousal pathology. Fisher S., Reason J. Handbook of Life Stress, Cognition and Health. 1988;631-651 Wiley, New York.
13. Wilson P.W.F., D'Agostino R.B., Levy D., Belanger A.M., Sibershatz H., Kannel W.B. Prediction of coronary heart disease using risk factor categories. Circulation. 97:1998;1837-1847.