Expression of myeloperoxidase (MPO) by neutrophils is necessary for their activation by anti-neutrophil cytoplasm autoantibodies (ANCA) against MPO

Journal of Leukocyte Biology

Volumn 73, Issue 6, 2003, Pages 841-849

  Reumaux, Dominique ^a   De Boer, Martin ^b   Meijer, Alexander B ^b   Duthilleul, Patrick ^a   Roos, Dirk ^b  

^a CENTRE HOSPITALIER DE VALENCIENNES   (France)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

H 2O2 carryover; MPO mutations; Myeloperoxidase deficiency; Neutrophil activation

Indexed keywords

AMINO ACID; GRANULOCYTE ANTIBODY; HYDROGEN PEROXIDE; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; MYELOPEROXIDASE; NEUTROPHIL CYTOPLASMIC ANTIBODY; NUCLEOTIDE; SUPEROXIDE; FLUORESCENT DYE; PEPTIDE; PEROXIDASE; RHODAMINE 123;

AMINO ACID SUBSTITUTION; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; DIFFUSION; DONOR; ENZYME ACTIVITY; ENZYME DEFICIENCY; EXON; GENE DELETION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; INTRON; LEUKOCYTE ACTIVATION; MUTATION; MUTATIONAL ANALYSIS; NORMAL HUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SPLICING; SITE DIRECTED MUTAGENESIS; CELL ADHESION; ENZYMOLOGY; GENETICS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; NEUTROPHIL; NUCLEOTIDE SEQUENCE;

ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; CELL ADHESION; DIFFUSION; DNA MUTATIONAL ANALYSIS; FLUORESCENT DYES; HUMANS; HYDROGEN PEROXIDE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; NEUTROPHIL ACTIVATION; NEUTROPHILS; PEPTIDES; PEROXIDASE; RHODAMINE 123; SUPEROXIDES;

EID: 0038341914     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1102567     Document Type: Article

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