Inhibition and alternate substrate studies on the mechanism of carbapenam synthetase from Erwinia carotovora

Biochemistry

Volumn 42, Issue 25, 2003, Pages 7836-7847

  Gerratana, Barbara ^a   Stapon, Anthony ^a   Townsend, Craig A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SEQUENCE HOMOLOGY;

ANTIBIOTICS; CATALYSTS; ENZYMES; GENES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; REACTION KINETICS;

BIOCHEMISTRY;

5 CARBOXYMETHYLPROLINE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ADIPIC ACID; CARBAPEN 2 EM CARBOXYLIC ACID; CARBAPENAM 3 CARBOXYLIC ACID; CARBAPENEM DERIVATIVE; CARBAPENEM SYNTHETASE; GLUTARIC ACID; PYROPHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; ATAXIA; BACTERIAL GENE; CARA GENE; CARB GENE; CARC GENE; CATALYSIS; DRUG SYNTHESIS; ENZYME ASSAY; ESCHERICHIA COLI; FERMENTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PECTOBACTERIUM CAROTOVORUM; PRIORITY JOURNAL; STEADY STATE;

ADENOSINE TRIPHOSPHATE; CARBAPENEMS; ENZYME INHIBITORS; KINETICS; MAGNESIUM; PECTOBACTERIUM CAROTOVORUM; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); ERWINIA; ESCHERICHIA COLI; NEGIBACTERIA; PECTOBACTERIUM CAROTOVORUM;

EID: 0038338723     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034361d     Document Type: Article

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