Positional isotope exchange analysis of the pantothenate synthetase reaction

Biochemistry

Volumn 42, Issue 17, 2003, Pages 5108-5113

  Williams, LaKenya ^a   Zheng, Renjian ^b   Blanchard, John S ^b   Raushel, Frank M ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; BINDING ENERGY; CATALYST ACTIVITY; DISSOCIATION; ENZYME INHIBITION; ISOTOPES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

POSITIONAL ISOTOPE EXCHANGE (PIX);

ENZYME KINETICS;

ADENOSINE TRIPHOSPHATE; BETA ALANINE; DEXTRO PANTOATE; OXYGEN 18; PANTOTHENATE SYNTHETASE; PANTOTHENIC ACID; PHOSPHATE; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL BINDING; CONCENTRATION (PARAMETERS); DISSOCIATION; ENZYME ACTIVE SITE; ENZYME INHIBITION; ISOTOPE LABELING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; REACTION ANALYSIS; REACTION TIME;

ADENOSINE TRIPHOSPHATE; ISOTOPE LABELING; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MYCOBACTERIUM TUBERCULOSIS; OXYGEN ISOTOPES; PEPTIDE SYNTHASES; PHOSPHATES; POTASSIUM COMPOUNDS;

MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 0038333266     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0340853     Document Type: Article

References (24)

1. Neidhardt, F. (1996) Escherichia coli and Salmonella typhimurium: cellular and molecular biology, 2nd ed., Vol. 1, pp 687-694, American Society for Microbiology, Washington, DC.
2. Abiko, Y. (1975) Metabolism of Coenzyme A, in Metabolic Pathways (Greenburg, D. M., Ed.) Academic Press, Inc., New York.
3. Mishra, P. K., and Drueckhammer, D. G. (2000) Chem. Rev. 100, 3283-3309.
4. DiRusso, C. C., Heimert, T. L., and Metzger, A. K. (1992) J. Biol. Chem. 267, 8685-8691.
5. Korchak, H. M., Kane, L. H., Rossi, M. W., and Corkey, B. E. (1994) J. Biol. Chem. 269, 30281-30287.
6. Dreier, J., Shah, A. N., and Khosla, C. (1999) J. Biol. Chem. 274, 25108-25112.
7. Lambalot, R. H., Gehring, A. M., Flugel, R. S., Zuber, P., LaCelle, M., Marahiel, M. A., Reid, R., Khosla, C., and Walsh, C. T. (1996) Chem. Biol. 3, 923-936.
8. Miyatake, K., Nakano, T., and Kitaoka, S. (1978) J. Nutr. Sci. Vitaminol. 24, 243-253.
9. Genschel, U., Powell, C. A., Abell, C., and Smith, A. G. (1999) Biochem. J. 341, 669-678.
10. von Delft, F., Lewendon, A., Dhanaraj, V., Blundell, T. L., Abell, C., and Smith, A. G. (2001) Structure 9, 439-450.
11. Zheng, R., and Blanchard, J. S. (2001) Biochemistry 40, 12904-12912.
12. Midelfort, C., and Rose, I. A. (1976) J. Biol. Chem. 251, 5881-5888.
13. Raushel, F. M., and Villafranca, J. J. (1988) Crit. Rev. Biochem. 23, 1-26.
14. Mullins, L. S., and Raushel, F. M. (1995) Methods Enzymol. 249, 398-425.
15. von der Saal, W., Chrysler, C. S., and Villafranca, J. J. (1985) Biochemistry 24, 2343-5350.
16. Healy, V. L., Mullins, L. S., Li, X., Hall, S. E., Raushel, F. M., and Walsh, C. T. (2000) Chem. Biol. 7, 505-514.
17. Mullins, L. S., Zawadzke, L. E., Walsh, C. T., and Raushel, F. M. (1990) J. Biol. Chem. 265, 8993-8998.
18. Risley, J. M., and Van Etten, R. L. (1978) J. Labeled Compd. Radiopharm. 15, 533-538.
19. Cohn, M., and Hu, A. (1980) J. Am. Chem. Soc. 102, 913-916.
20. Wimmer, M. J., Rose, I. A., Powers, S. G., and Meister, A. (1979) J. Biol. Chem. 254, 1854-1859.
21. Hilscher, L. W., Hanson, C., Russell, D. W., and Raushel, F. M. (1985) Biochemistry 24, 5888-5893.
22. Lowe, G., Sproat, B. S., and Tansley, G. (1983) Eur. J. Biochem. 130, 341-345.
23. Hester, L. S., and Raushel, F. M. (1987) Biochemistry 26, 6465-6471.
24. Cleland, W. W. (1967) Adv. Enzymol. Relat. Areas Mol. Biol. 29, 1-32.