The human telomeric sequence (T2AG3)n is efficiently cross-linked by AN1 binding to the platinum of a trans-Pt(NH3)2 chelate of an antisense oligo-2′-o-methylribonucleotide

European Journal of Inorganic Chemistry

Volumn , Issue 8, 2003, Pages 1641-1644

  Perrier, Sandrine ^a   Seela, Frank ^b   Schwartz, Annie ^c   Leng, Marc ^c   Chottard, Jean Claude ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b UNIVERSITY OF OSNABRÜCK   (Germany)

^c CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

Author keywords

Bioinorganic chemistry; Chelates; DNA; Platinum; RNA

Indexed keywords

BIOCHEMISTRY; CHELATION; CROSSLINKING; DNA; OLIGONUCLEOTIDES;

ANTISENSE; ANTISENSE OLIGONUCLEOTIDES; AS-LIGANDS; BIOINORGANIC CHEMISTRY; CHELATE; DNA TARGETS; HYBRID DUPLEX; NMR ANALYSIS; TELOMERIC DNA; TELOMERIC SEQUENCES;

PLATINUM;

ADENINE DERIVATIVE; ARGININE; BRIDGED COMPOUND; CHELATE; COMPLEMENTARY DNA; DEAZAADENINE; GUANINE; NUCLEOTIDE DERIVATIVE; OLIGO 2' O METHYLRIBONUCLEOTIDE; OLIGONUCLEOTIDE; PLATINUM; PURINE; THYMINE; UNCLASSIFIED DRUG; URIDINE;

AMINO ACID SEQUENCE; ARTICLE; ATOM; BINDING SITE; CHEMICAL REACTION; COMPARATIVE STUDY; CROSS LINKING; DNA STRAND; GENE TARGETING; HYBRID; KINETICS; NUCLEAR MAGNETIC RESONANCE; TELOMERE;

EID: 0038328961     PISSN: 14341948     EISSN: None     Source Type: Journal    
DOI: 10.1002/ejic.200390216     Document Type: Article

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