Interstrand crosslinking reaction in transplatin-modified oligo-2'-O-methyl Ribonucleotide-RNA hybrids

Antisense and Nucleic Acid Drug Development

Volumn 7, Issue 4, 1997, Pages 397-402

  Colombier, Caroline ^a   Boudvillain, Marc ^a   Leng, Marc ^a  

^a CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

INORGANIC SALT; OLIGODEOXYRIBONUCLEOTIDE; RNA; TRANSPLATIN;

ARTICLE; DNA CROSS LINKING; DNA RNA HYBRIDIZATION; PRIORITY JOURNAL; THERMOSTABILITY;

EID: 0030763351     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1997.7.397     Document Type: Article

References (5)

1. AGRAWAL, S. (1992). Antisense oligonucleotides as antiviral agents. Trends Biotechnol. 10, 152-158.
2. ANIN, M.F., and LENG, M. (1990). Distortions induced in double-stranded oligonucleotides by the binding of cis- or trans-diamminedichloroplatinum(II) to the d(GTG) sequence. Nucleic Acids Res. 18, 4295-4400.
3. BONHAM, M.A., BROWN, S., BOYD, A.L., BROWN, P.H., BRUCKENSTEIN, D.A., HANVEY, J.C., THOMSON, S.A., PIPE, A., HASSMAN, F., BISI, J.E., FROEHLER, B.C., MATTEUCI, M.D., WAGNER, R.W., NOBLE, S.A., and BABISS, L.E. (1995). An assessment of the antisense properties of RNase H-competent and steric-blocking oligomers. Nucleic Acids Res. 23, 1197-1203.
4. BOUDVILLAIN, M., DALBIES, R., AUSSOURD, C., and LENG, M. (1995). Intrastrand cross-links are not formed in the reaction between transplatin and native DNA: Relation with the clinical inefficiency of transplatin. Nucleic Acids Res. 23, 2381-2388.
5. WOOLF, T.D. (1995). To cleave or not to cleave: Ribozymes and antisense. Antisense Res. Dev. 5, 227-232.