Mitochondrial targeting of normal and mutant protoporphyrinogen oxidase

Journal of Biological Chemistry

Volumn 278, Issue 15, 2003, Pages 13376-13381

  Von und zu Fraunberg, Mikael ^a,c   Nyrönen, Tommi ^b   Kauppinen, Raili ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b IT Center for Science   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOSYNTHESIS; FLUORESCENCE; HYDROPHOBICITY;

MOLECULAR MODELING;

ENZYMES;

GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; ISOLEUCINE; LEUCINE; MITOCHONDRIAL PROTEIN; MUTANT PROTEIN; PROTOPORPHYRINOGEN OXIDASE; RECEPTOR PROTEIN; TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 20; UNCLASSIFIED DRUG; FLAVOPROTEIN; OXIDOREDUCTASE; PPOX PROTEIN, HUMAN; PRIMER DNA;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HEME SYNTHESIS; HYDROPHOBICITY; MITOCHONDRION; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN MOTIF; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; CERCOPITHECUS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTAGENESIS; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

ANIMALIA;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CERCOPITHECUS AETHIOPS; COS CELLS; DNA PRIMERS; FLAVOPROTEINS; HUMANS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; OXIDOREDUCTASES; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTOPORPHYRINOGEN OXIDASE; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFECTION;

EID: 0038306834     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300151200     Document Type: Article

References (36)

1. Brenner, D. A., and Bloomer, J. R. (1980) N. Engl. J. Med. 302, 765-769
2. Dailey, H. A. (1990) in Biosynthesis of Heme and Chlorophylls (Dailey, H. A., ed) pp. 123-161, McGraw-Hill, New York
3. Kappas, A., Sassa, S., Galbraith, R. A., and Nordmann, Y. (1995) in The Metabolic and Molecular Bases of Inherited Diseases (Scriver, C. R., Beaudet, A., Sly, W. S., and Valle, D., eds) 7th Ed., pp. 2116-2127, McGrawHill, New York
4. Day, R. S. (1986) Semin. Dermatol. 5, 138-154
5. Mustajoki, P. (1980) Q. J. Med. 49, 191-203
6. Deybach, J. C., da Silva, V., Grandchamp, B., and Nordmann, Y. (1985) Eur. J. Biochem. 149, 431-435
7. Ferreira, G. C., Andrew, T. L., Karr, S. W., and Dailey, H. A. (1988) J. Biol. Chem. 263, 3835-3839
8. Arnould, S., Takahashi, M., and Camadro, J. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 14825-14830
9. Pfanner, N. (2000) Curr. Biol. 10, R412-5
10. von Heijne, G. (1986) EMBO J. 5, 1335-1342
11. Roise, D., and Schatz, G. (1988) J. Biol. Chem. 263, 4509-4511
12. Ramage, L., Junne, T., Hahne, K., Lithgow, T., and Schatz, G. (1993) EMBO J. 12, 4115-4123
13. Brix, J., Dietmeier, K., and Pfanner, N. (1997) J. Biol. Chem. 272, 20730-20735
14. Voos, W., Martin, H., Krimmer, T., and Pfanner, N. (1999) Biochim. Biophys. Acta 1422, 235-254
15. Herrmann, J. M., and Neupert, W. (2000) Curr. Opin. Microbiol. 3, 210-214
16. Wierenga, R. K., Terpstra, P., and Hol, W. G. (1986) J. Mol. Biol. 187, 101-107
17. Nishimura, K., Taketani, S., and Inokuchi, H. (1995) J. Biol. Chem. 270, 8076-8080
18. Warnich, L., Kotze, M. J., Groenewald, I. M., Groenewald, J. Z., van Brakel, M. G., van Heerden, C. J., de Villiers, J. N., van de Ven, W. J., Schoenmakers, E. F., Taketani, S., and Retief, A. E. (1996) Hum. Mol. Genet. 5, 981-984
19. Whatley, S. D., Puy, H., Morgan, R. R., Robreau, A. M., Roberts, A. G., Nordmann, Y., Elder, G. H., and Deybach, J. C. (1999) Am. J. Hum. Genet. 65, 984-994
20. Frank, J., Jugert, F. K., Merk, H. F., Kalka, K., Goerz, G., Anderson, K., Bickers, D. R., Poh-Fitzpatrick, M. B., and Christiano, A. M. (2001) J. Investig. Dermatol. 116, 821-823
21. Kauppinen, R., Timonen, K., von und zu Fraunberg, M., Laitinen, E., Ahola, H., Tenhunen, R., Taketani, S., and Mustajoki, P. (2001) J. Investig. Dermatol, 116, 610-613
22. von und zu Fraunberg, M., Tenhunen, R., and Kauppinen, R. (2001) Mol. Med. 7, 320-328
23. Peitsch, M. C. (1996) Biochem. Soc. Trans. 24, 274-279
24. Koradi, R., Billeter, M., and Wüthrich, K. (1996) J. Mol. Graph. Model. 14, 52-55
25. Abe, Y., Shodai, T., Muto, T., Mihara, K., Torii, H., Nishikawa, S., Endo, T., and Kohda, D. (2000) Cell 100, 551-560
26. Johnson, M. S., and Overington, J. P. (1993) J. Mol. Biol. 233, 716-738
27. Horie, C., Suzuki, H., Sakaguchi, M., and Mihara, K. (2002) Mol. Biol. Cell 13, 1615-1625
28. Rizzutto, R., Pinton, P., Carrington, W., Fay, F. S., Fogarty, K. E., Lifshitz, L. M., Tuft, R. A., and Pozzan, T. (1998) Science 280, 1763-1766
29. Tzschoppe, K., Kohlwein, S. D., and Rodel, G. (2000) Biol. Chem. 381, 1175-1183
30. Brix, J., Rüdiger, S., Bukau, B., Scheider-Mergener, J., and Pfanner, N. (1999) J. Biol. Chem. 274, 16522-16530
31. Michaelis, U., Korte, A., and Rodel, G. (1991) Mol. Gen. Genet. 230, 177-185
32. Krause-Buchholz, U., Tzschoppe, K., Paret, C., Ostermann, K., and Rodel, G. (2000) Yeast 16, 353-363
33. DeLabre, M. L., Nett, J. H., and Trumpower, B. L. (1999) FEBS Lett. 449, 201-205
34. Folsch, H., Gaume, B., Brunner, M., Neupert, W., and Stuart, R. A. (1998) EMBO J. 17, 6508-6515
35. Zara, V., Palmieri, F., Mahlke, K., and Pfanner, N. (1992) J. Biol. Chem. 267, 12077-12081
36. Sander, C., and Schneider, R. (1991) Proteins 9, 56-68